Comparative study of active and inactive hepatocarcinogens using a QSAR-based prediction model

Molecular and Cellular Toxicology

Volumn 8, Issue 4, 2012, Pages 383-391

  Kang, Jin Seok ^a   Kang, Sukmo ^b   Ryu, Doug Young ^b   Lee, Yun Seok ^a   Lee, Jong Kwon ^c   Kang, Tae Seok ^c   Park, Han Jin ^d   Yoon, Seokjoo ^d  

^a Namseoul University   (South Korea)

^b Seoul National University   (South Korea)

^c National Institute of Food and Drug Safety Evaluation   (South Korea)

^d Korea Institute of Toxicology   (South Korea)

Author keywords

Gene set enrichment analysis (GSEA); Hepatocarcinogen; In vitro assay; Microarray; Principal component analysis (PCA)

Indexed keywords

CARCINOGEN; GLYCYRRHETINIC ACID; GRISEOFULVIN; HEPATOCARCINOGEN; HYDROCORTISONE; LITHOCHOLIC ACID; MONOCROTALINE; PRASTERONE; PREDNISOLONE; PREDNISONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; CYTOTOXICITY; GENE EXPRESSION; LIVER CARCINOGENESIS; LIVER CELL; MICROARRAY ANALYSIS; NONHUMAN; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RNA EXTRACTION;

EID: 84876211794     PISSN: 1738642X     EISSN: 20928467     Source Type: Journal    
DOI: 10.1007/s13273-012-0047-z     Document Type: Article

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