B-cell-activating factor is a regulator of adipokines and a possible mediator between adipocytes and macrophages

Experimental and Molecular Medicine

Volumn 45, Issue 1, 2013, Pages

  Kim, Mi Young ^a   Kim, Do Hwan ^a   Do, Myoung Sool ^a  

^a Handong University   (South Korea)

Author keywords

3T3 L1 adipocytes; B cell activating factor; Coculture; Diet induced obesity; Inflammation

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; B CELL ACTIVATING FACTOR; B CELL ACTIVATING FACTOR RECEPTOR; BETA ACTIN; CYCLOOXYGENASE 2; HAPTOGLOBIN; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE SYNTHASE; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WHITE ADIPOSE TISSUE;

EID: 84876197332     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.4     Document Type: Article

References (32)

1. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005; 115: 911-919.
2. Arner P. Insulin resistance in type 2 diabetes - role of the adipokines. Curr Mol Med 2005; 5: 333-339.
3. Lau DC, Dhillon B, Yan H, Szmitko PE, Verma S. Adipokines: molecular links between obesity and atherosclerosis. Am J Physiol Heart Circ Physiol 2005; 288: H2031-H2041.
4. Beuther DA, Weiss ST, Sutherland ER. Obesity and asthma. Am J Respir Crit Care Med 2006; 174: 112-119.
5. Mackay F, Woodcock SA, Lawton P, Ambrose C, Baetscher M, Schneider P et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 1999; 190: 1697-1710.
6. Woo YJ, Yoon BY, Jhun JY, Oh HJ, Min SW, Cho ML et al. Regulation of B cell activating factor(BAFF) receptor expression by NF-kB signaling in rheumatoid arthritis B cells. Exp Mol Med 2011; 43: 350-357.
7. Craxton A, Magaletti D, Ryan EJ, Clark EA. Macrophage- and dendritic celldependent regulation of human B-cell proliferation requires the TNF family ligand BAFF. Blood 2003; 101: 4464-4471.
8. Schneider P, MacKay F, Steiner V, Hofmann K, Bodmer JL, Holler N et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999; 189: 1747-1756.
9. Moore PA, Belvedere O, Orr A, Pieri K, LaFleur DW, Feng P et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 1999; 285: 260-263.
10. Mackay F, Pascal S. Cracking the BAFF code. Nat Rev Immunol 2009; 9: 491-502.
11. Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML et al. B cell-activation factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells. J Immunol 2004; 173: 807-817.
12. Huard B, Schneider P, Mauri D, Tschopp J, French LE. T cell costimulation by the TNF ligand BAFF. J Immunol 2001; 167: 6225-6231.
13. von Bulow GU, Bram RJ. NF-AT activation induced by a CAML interacting member of the tumor necrosis factor receptor superfamily. Science 1997; 278: 138-141.
14. Thompson JS, Bixler SA, Qian F, Vora K, Scott ML, Cachero TG et al. BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF. Science 2001; 293: 2108-2111.
15. Mackay F, Ambrose C. The TNF family members BAFF and APRIL: the growing complexity. Cytokine Growth Factor Rev 2003; 14: 311-324.
16. Brennan AM, Mantzoros CS. Drug insight: the role of leptin in human physiology and pathophysiology emerging clinical applications. Nat Clin Pract Endocrinol Metab 2006; 2: 318-327.
17. Wellen KE, Hotamisligil GS. Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 2003; 112: 1785-1788.
18. Diez JJ, Iglesias P. The role of the novel adipocyte-derived hormone adiponectin in human disease. Eur J Endocrinol 2003; 148: 293-300.
19. Xia M, Sui Z. Recent developments in CCR2 antagonists. Expert Opin Ther Patents 2009; 19: 295-303.
20. Gabay C. Interleukin-6 and chronic inflammation. Arthritis Res Ther 2006; 8(Suppl 2): S3.
21. Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92: 347-355.
22. Christopher SW, Moss M, Raymond ND. The role of cyclooxygenases in inflammation, cancer, and development. Oncogene 1999; 18: 7908-7916.
23. Quaye IK. Haptoglobin, inflammation, and disease. Trans R Soc Trop Med Hyg 2008; 102: 735-742.
24. Do MS, Jeong HS, Choi BH, Hunter L, Langley S, Pazmany L et al. Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-alpha-treated SGBS human adipocytes. Yonsei Med J 2006; 47: 729-736.
25. Pelekanou V, Kampa M, Kafousi M, Darivianaki K, Sanidas E, Tsiftsis DD et al. Expression of TNF-superfamily members BAFF and APRIL in breast cancer: Immunohistochemical study in 52 invasive ductal breast carcinomas. BMC Cancer 2008; 20: 76.
26. Alexaki VI, Notas G, Pelekanou V, Kampa M, Valkanou M, Theodoropoulos P et al. Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development. J Immunol 2009; 183: 5948-5956.
27. Hamada M, Abe M, Miyake T, Kawasaki K, Tada F, Furukawa S et al. B cellactivating factor controls the production of adipokines and induces insulin resistance. Obesity 2011; 19: 1915-1922.
28. Kim YH, Choi BH, Cheon HG, Do MS. B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation. Exp Mol Med 2009; 41: 208-216.
29. Takayoshi S, Junko N, Yoshihiro OA. Paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor a. Arterioscler Thromb Vasc Biol 2005; 25: 2062-2068.
30. Whitehead JP, Richards AA, Hickman IJ, Macdonald GA, Prins JB. Adiponectin - a key adipokine in the metabolic syndrome. Diabetes Obes Metab 2006; 8: 264-280.
31. Patel SB, Reams GP, Spear RM, Freeman RH, Villarreal D. Leptin: linking obesity, the metabolic syndrome, and cardiovascular disease. Curr Hypertens Rep 2008; 10: 131-137.
32. Takahashi K, Mizuarai S, Araki H, Mashiko S, Ishihara A, Kanatani A et al. Adiposity elevates plasma MCP-1 levels leading to the increased CD11bpositive monocytes in mice. J Biol Chem 2003; 278: 46654-46660.