Inflammatory gene expression patterns revealed by DNA microarray analysis in TNF-α-treated SGBS human adipocytes

Yonsei Medical Journal

Volumn 47, Issue 5, 2006, Pages 729-736

  Do, Myoung Sool ^a   Jeong, Hun Soon ^a   Choi, Bong Hyuk ^a   Hunter, Leif ^b   Langley, Stuart ^c   Pazmany, Laszlo ^c   Trayhurn, Paul ^b  

^a Handong University   (South Korea)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

Author keywords

Adipose tissue; Cytokine; DNA microarray; Inflammation; SGBS; TNF

Indexed keywords

A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1 PREPROTEIN; DYE; EOTAXIN; FIBRONECTIN; FIBRONECTIN 1 ISOFORM 1 PREPROTEIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 1; MATRIX METALLOPROTEINASE 15 PREPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PROSTAGLANDIN SYNTHASE; PROTEIN ADAMTS1; PROTEIN PRECURSOR; RGS2 PROTEIN; RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ADIPOCYTE; ARTICLE; ATHEROSCLEROSIS; CELL CULTURE; CELL DIFFERENTIATION; CELL HYBRIDIZATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE FUNCTION; HUMAN; HUMAN CELL; INFLAMMATION; OBESITY; PATHOGENESIS; PROADIPOCYTE; PROTEIN FAMILY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIMPSON GOLABI BEHMEL SYNDROME; UPREGULATION;

ADIPOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION MEDIATORS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33750734344     PISSN: 05135796     EISSN: 05135796     Source Type: Journal    
DOI: 10.3349/ymj.2006.47.5.729     Document Type: Article

References (22)

1. Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004;89:2548-56.
2. Trayhurn P, Wood IS. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans 2005;33:1078-81.
3. Fautuzzi G. Adipose tissue, adipokines, and inflammation. J Allergy Clin Immunol 2005;15:911-20.
4. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 2002;105:804-9.
5. Yudkin JS. Adipose tissue, insulin action and vascular disease: inflammatory signals. Int J Obes Relat Metab Disord 2003;27 (Suppl 3):S25-8.
6. Sethi JK, Hotamisligil GS. The role of TNFα in adipocyte metabolism. Semin Cell Dev Biol 1999;10:19-29.
7. Grunfeld C, Feingold KR. Regulation of lipid metabolism by cytokines during host defense. Nutrition 1996; 12(1 Suppl):S24-6.
8. Wabitsch M, Brenner RE, Melzner I, Braun M, Moller P, Heinze E, et al. Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation. Int J Obes Relat Metab Disord 2001;25: 8-15.
9. Sartipy P, Loskutoff DJ. Monocyte chemoattractant protein 1 in obesity and insulin resistance. Proc Natl Acad Sci USA 2003;100:7265-70.
10. Takahashi K, Mizuarai S, Araki H, Mashiko S, Ishihara A, Kanatani A, et al. Adiposity elevates plasma MCP-1 levels leading to the increased CD11b-positive monocytes in mice. J Biol Chem 2003;278:46654-60.
11. Kodali RB, Kim WJ, Galaria II, Miller C, Schecter AD, Lira SA, et al. CCL11 (Eotaxin) inducess CCR3-dependent smooth muscle cell migration. Arterioscler Thromb Vasc Biol 2004;24:1211-6.
12. De Caterina R, Bernini W, Carluccio MA, Liao JK, Libby P. Structural requirements for inhibition of cytokine-induced endothelial activation by unsaturated fatty acids. J Lipid Res 1998;39:1062-70.
13. Lyon CJ, Law RE, Hsueh WA. Minireview: adiposity, inflammation, and atherogenesis. Endocrinology 2003; 144:2195-200.
14. Stetler-Stevenson WG, Liotta LA, Kleiner DE Jr. Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. FASEB J 1993;7:1434-41.
15. Hynes RO. The dynamic dialogue between cells and matrices: implications of fibronectin's elasticity. Proc Natl Acad Sci USA 1999;96:2588-90.
16. Caterson B, Flannery CR, Hughes CE, Little CB. Mechanisms involved in cartilage proteoglycan catabolism. Matrix Biol 2000;19:333-44.
17. Stanton H, Ung L, Fosang AJ. The 45 kDa collagen-binding fragment of fibronectin induces matrix metallo-proteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases. Biochem, J 2002,364: 181-90.
18. Okada Y. Proteinase and matrix degradation, In: Ruddy S, Harris ED Jr, Sledge CB, editors. Kelly's Textbook of Rheumatology. Philadelphia: WB Saunders Company; 2001. p.55-72.
19. Tetlow LC, Adlam DJ, Woolley DE. Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: associations with degenerative changes. Arthritis Rheum 2001;44:585-94.
20. Voros G, Maquoi E, Collen D, Lijnen HR. Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-alpha, TNF-alpha converting enzyme and ADAMTS family members in murine fat territories. Biochim Biophys Acta 2003;1625:36-42.
21. Boeuf S, Klingenspor M, Van Hal NL, Schneider T, Keijer J, Klaus S. Differential gene expression in white and brown preadipocytes. Physiol Genomics 2001;7:15-25.
22. Debets R, Timans JC, Homey B, Zurawski S, Sana TR, Lo S, et al. Two novel IL-1 family members, IL-1delta and IL-1epsilon function as an antagonist and agonist of NF-κB activation through the orphan IL-1 receptor-related protein 2. J Immunol 2001;167:1440-6.