Lactate clearance as a predictor of mortality in trauma patients

Journal of Trauma and Acute Care Surgery

Volumn 74, Issue 4, 2013, Pages 999-1004

  Odom, Stephen R ^a   Howell, Michael D ^b   Silva, George S ^c   Nielsen, Victoria M ^c   Gupta, Alok ^a   Shapiro, Nathan I ^c   Talmor, Daniel ^c  

^a Trauma and Surgical Critical Care   (United States)

^b Division of Pulmonary   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

lactate; lactate clearance; Trauma

Indexed keywords

LACTIC ACID;

ADULT; ARTICLE; BLOOD PRESSURE; CLEARANCE; COHORT ANALYSIS; CORRELATION ANALYSIS; FEMALE; GLASGOW COMA SCALE; HEART RATE; HUMAN; INJURY; INJURY SCALE; INJURY SEVERITY; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MORTALITY; PREDICTIVE VALUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK;

AGED; BIOLOGICAL MARKERS; FEMALE; FOLLOW-UP STUDIES; GLASGOW COMA SCALE; HUMANS; LACTIC ACID; MALE; MASSACHUSETTS; MIDDLE AGED; ODDS RATIO; PROGNOSIS; REGISTRIES; RETROSPECTIVE STUDIES; SURVIVAL RATE; TRAUMA CENTERS; WOUNDS AND INJURIES;

EID: 84876194825     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e3182858a3e     Document Type: Article

References (23)

1. Mizock BA, Falk JL. Lactic acidosis in critical illness. Crit Care Med. 1992;20:80-93.
2. Callaway DW, Shapiro NI, Donnino MW, Baker C, Rosen CL. Serum lactate and base deficit as predictors of mortality in normotensive elderly blunt trauma patients. J Trauma. 2009;66:1040-1044.
3. Vandromme MJ, Griffin RL, Weinberg JA, Rue LW 3rd, Kerby JD. Lac-tate is a better predictor than systolic blood pressure for determining blood requirement and mortality: could prehospital measures improve trauma triage? J Am Coll Surg. 2010;210:861-867, 867-869.
4. Paladino L, Sinert R, Wallace D, Anderson T, Yadav K, Zehtabchi S. The utility of base deficit and arterial lactate in differentiating major from minor injury in trauma patients with normal vital signs. Resuscitation. 2008;77:363-368.
5. Nguyen HB, Rivers EP, Knoblich BP, et al. Early lactate clearance is associated with improved outcome in severe sepsis and septic shock. Crit Care Med. 2004;32:1637-1642.
6. Jansen TC, van Bommel J, Woodward R, Mulder PG, Bakker J. Association between blood lactate levels, Sequential Organ Failure Assessment subscores, and 28-day mortality during early and late intensive care unit stay: a retrospective observational study. Crit Care Med. 2009;37: 2369-2374.
7. Husain FA, Martin MJ, Mullenix PS, Steele SR, Elliott DC. Serum lactate and base deficit as predictors of mortality and morbidity. Am J Surg. 2003;185:485-491.
8. McNelis J, Marini CP, Jurkiewicz A, et al. Prolonged lactate clearance is associated with increased mortality in the surgical intensive care unit. Am J Surg. 2001;182:481-485.
9. Claridge JA, Crabtree TD, Pelletier SJ, Butler K, Sawyer RG, Young JS. Persistent occult hypoperfusion is associated with a significant increase in infection rate and mortality in major trauma patients. J Trauma. 2000; 48:8-14; discussion 14-15.
10. Crowl AC, Young JS, Kahler DM, Claridge JA, Chrzanowski DS, Pomphrey M. Occult hypoperfusion is associated with increased morbidity in patients undergoing early femur fracture fixation. J Trauma. 2000; 48:260-267.
11. Jansen TC, van Bommel J, Schoonderbeek FJ, et al. Early lactate-guided therapy in intensive care unit patients: a multicenter, open-label, randomized controlled trial. Am J Respir Crit Care Med. 2010;182:752-761.
12. Lavery RF, Livingston DH, Tortella BJ, Sambol JT, Slomovitz BM, Siegel JH. The utility of venous lactate to triage injured patients in the trauma center. J Am Coll Surg. 2000;190:656-664.
13. Shapiro NI, Howell MD, Talmor D, et al. Serum lactate as a predictor of mortality in emergency department patients with infection. Ann Emerg Med. 2005;45:524-528.
14. Howell MD, Donnino M, Clardy P, Talmor D, Shapiro NI. Occult hypo-perfusion and mortality in patients with suspected infection. Intensive Care Med. 2007;33:1892-1899.
15. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13:818-829.
16. Butcher I, Maas AI, Lu J, et al. Prognostic value of admission blood pressure in traumatic brain injury: results from the IMPACT study. J Neurotrauma. 2007;24:294-302.
17. Okumiya K, Matsubayashi K, Wada T, et al. A U-shaped association between home systolic blood pressure and four-year mortality in community-dwelling older men. J Am Geriatr Soc. 1999;47:1415-1421.
18. Mikkelsen ME, Miltiades AN, Gaieski DF, et al. Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock. Crit Care Med. 2009;37:1670-1677.
19. Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J. Lactate clearance and survival following injury. J Trauma. 1993;35:584-588; discussion 8-9.
20. Tuchschmidt J, Oblitas D, Fried JC. Oxygen consumption in sepsis and septic shock. Crit Care Med. 1991;19:664-671
21. Boyd O, Grounds RM, Bennett ED. A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. JAMA. 1993;270:2699-2707.
22. Groeneveld AB, Kester AD, Nauta JJ, Thijs LG. Relation of arterial blood lactate to oxygen delivery and hemodynamic variables in human shock states. Circ Shock. 1987;22:35-53.
23. Levraut J, Ciebiera JP, Chave S, et al. Mild hyperlactatemia in stable septic patients is due to impaired lactate clearance rather than overproduction. Am J Respir Crit Care Med. 1998;157:1021-1026.