Early lactate-guided therapy in intensive care unit patients: A multicenter, open-label, randomized controlled trial

American Journal of Respiratory and Critical Care Medicine

Volumn 182, Issue 6, 2010, Pages 752-761

  Jansen, Tim C ^a   Van Bommel, Jasper ^a   Schoonderbeek, F Jeanette ^b   Sleeswijk Visser, Steven J ^c   Van Der Klooster, Johan M ^d   Lima, Alex P ^a   Willemsen, Sten P ^a   Bakker, Jan ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b IKAZIA HOSPITAL   (Netherlands)

^c REINIER DE GRAAF HOSPITAL   (Netherlands)

^d SINT FRANCISCUS GASTHUIS   (Netherlands)

Author keywords

Central venous oxygenation; Early goal directed therapy; Lactate; Oxygen delivery; Shock

Indexed keywords

INOTROPIC AGENT; LACTIC ACID; VASODILATOR AGENT; BIOLOGICAL MARKER;

ADULT; ARTICLE; ARTIFICIAL VENTILATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICAL ILLNESS; FEMALE; FLUID INTAKE; HOSPITAL ADMISSION; HOSPITAL DISCHARGE; HUMAN; HYPERLACTATEMIA; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; MONITORING; MORTALITY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESUSCITATION; RISK FACTOR; SCORING SYSTEM; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; WEANING; AGED; BLOOD; INTENSIVE CARE; KAPLAN MEIER METHOD; LENGTH OF STAY; METHODOLOGY; MIDDLE AGED; PROPORTIONAL HAZARDS MODEL; STATISTICS; TIME; TREATMENT OUTCOME;

AGED; BIOLOGICAL MARKERS; CRITICAL ILLNESS; FEMALE; HOSPITAL MORTALITY; HUMANS; INTENSIVE CARE; INTENSIVE CARE UNITS; KAPLAN-MEIERS ESTIMATE; LACTIC ACID; LENGTH OF STAY; MALE; MIDDLE AGED; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; TIME FACTORS; TREATMENT OUTCOME;

EID: 77954930936     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200912-1918OC     Document Type: Article

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