Insular cortex abnormalities in psychotic major depression: Relationship to gender and psychotic symptoms

Neuroscience Research

Volumn 75, Issue 4, 2013, Pages 331-339

  Cohen, Jeremy D ^a,c   Nichols, Taylor ^a   Keller, Jennifer ^a   Gomez, Rowena G ^a,b   Schatzberg, Alan F ^a   Reiss, Allan L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PALO ALTO UNIVERSITY   (United States)

^c XAVIER UNIVERSITY OF LOUISIANA   (United States)

Author keywords

Cortex; Insula; Major depression; Morphometry; Psychosis

Indexed keywords

ADULT; AFFECTIVE PSYCHOSIS; ARTICLE; BRAIN SIZE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION COEFFICIENT; DEPRESSIVE PSYCHOSIS; DISEASE SEVERITY; FEMALE; GENDER; HUMAN; INSULA; MAJOR DEPRESSION; MALE; MORPHOMETRICS; NUCLEAR MAGNETIC RESONANCE; OUTPATIENT; PRIORITY JOURNAL; SCHIZOPHRENIA;

ADULT; ANALYSIS OF VARIANCE; CASE-CONTROL STUDIES; CEREBRAL CORTEX; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; PSYCHOMETRICS; PSYCHOTIC DISORDERS; SEX CHARACTERISTICS;

EID: 84876122427     PISSN: 01680102     EISSN: 18728111     Source Type: Journal    
DOI: 10.1016/j.neures.2013.02.005     Document Type: Article

References (39)

1. Brebion G., Smith M.J., Amador X., Malaspina D., Gorman J.M. Word recognition, discrimination accuracy, and decision bias in schizophrenia: association with positive symptomatology and depressive symptomatology. J. Nerv. Ment. Dis. 1998, 186:604-609.
2. Bushara K.O., Grafman J., Hallett M. Neural correlates of auditory-visual stimulus onset asynchrony detection. J. Neurosci. 2001, 21:300-304.
3. Calvert G.A. Crossmodal processing in the human brain: insights from functional neuroimaging studies. Cereb. Cortex 2001, 11:1110-1123.
4. Chen S., Li L., Xu B., Liu J. Insular cortex involvement in declarative memory deficits in patients with post-traumatic stress disorder. BMC Psychiatry 2009, 9:39.
5. Cohen J.D., Mock J.R., Nichols T., Zadina J., Corey D.M., Lemen L., Bellugi U., Gallaburda A., Reiss A.L., Foundas A.L. Morphometry of human insular cortex and insular volume reduction in Williams syndrome. J. Psychiatr. Res. 2009, 44:81-89.
6. Cohen J.D., Nichols T., Brignone L., Hall S.S., Reiss A.L. Insular volume reduction in fragile X syndrome. Int. J. Dev. Neurosci. 2011, 29:489-494.
7. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr. Opin. Neurobiol. 2003, 13:500-505.
8. Crespo-Facorro B., Kim J., Andreasen N.C., O'Leary D.S., Bockholt H.J., Magnotta V. Insular cortex abnormalities in schizophrenia: a structural magnetic resonance imaging study of first-episode patients. Schizophr. Res. 2000, 46:35-43.
9. Farrer C., Franck N., Georgieff N., Frith C.D., Decety J., Jeannerod M. Modulating the experience of agency: a positron emission tomography study. Neuroimage 2003, 18:324-333.
10. First, M.B., Spitzer, R.L., Gibbon, M., Williams, J.B.W., 1997. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Patient Edition (SCID-I/P). New York State Psychiatric Institute, Biometrics Research, New York.
11. Foundas A.L., Eure K.F., Seltzer B. Conventional MRI volumetric measures of parietal and insular cortex in Alzheimer's disease. Prog. Neuropsychopharmacol. Biol. Psychiatry 1996, 20:1131-1144.
12. Frith C., Dolan R.J. Brain mechanisms associated with top-down processes in perception. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 1997, 352:1221-1230.
13. Goldstein J.M., Goodman J.M., Seidman L.J., Kennedy D.N., Makris N., Lee H., et al. Cortical abnormalities in schizophrenia identified by structural magnetic resonance imaging. Arch. Gen. Psychiatry 1999, 56:537-547.
14. Gomez R.G., Fleming S.H., Keller J., Flores B., Kenna H., DeBattista C., Solvason B., Schatzberg A.F. The neuropsychological profile of psychotic major depression and its relation to cortisol. Biol. Psychiatry 2006, 60:472-478.
15. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 1960, 23:56-62.
16. Jeste D.V., Heaton S.C., Paulsen J.S., Ercoli L., Harris J., Heaton R.K. Clinical and neuropsychological comparison of psychotic depression with nonpsychotic depression and schizophrenia. Am. J. Psychiatry 1996, 153:490-496.
17. Karnath H.O., Baier B., Nagele T. Awareness of the functioning of one's own limbs mediated by the insular cortex?. J. Neurosci. 2005, 25(31):7134-7138.
18. Kasai K., Shenton M.E., Salisbury D.F., Onitsuka T., Toner S.K., Yurgelin-Todd D., et al. Differences and similarities in insular and temporal pole MRI gray matter volume abnormalities in first-episode schizophrenia and affective psychosis. Arch. Gen. Psychiatry 2003, 60:1069-1077.
19. Kates W.R., Warsofsky I.S., Patwardhan A., Abrams M.T., Liu A.M., Naidu S., et al. Automated Talairach atlas-based parcellation and measurement of cerebral lobes in children. Psychiatry Res. 1999, 91:11-30.
20. Keller J., Shen L., Gomez R.G., Garrett A., Solvason H.B., Reiss A.L., Schatzberg A.F. Hippocampal and amygdalar volumes in psychotic and nonpsychotic unipolar depression. Am. J. Psychiatry 2008, 165:872-880.
21. Keller J., Flores B., Gomez R.G., Solvason H.B., Kenna H., Williams G.H., Schatzberg A.F. Cortisol circadian rhythm alterations in psychotic major depression. Biol. Psychiatry 2006, 60:275-281.
22. Kim D.K., Kim B.L., Sohn S.E., Lim S.W., Na D.G., Paik C.H., et al. Candidate neuroanatomic substrates of psychosis in old-aged depression. Prog. Neuropsychopharmacol. Biol. Psychiatry 1999, 23:793-807.
23. Kubicki M., Shenton M.E., Salisbury D.F., Hirayasu Y., Kasai K., Kikinis R., et al. Voxel-based morphometric analysis of gray matter in first episode schizophrenia. Neuroimage 2002, 17:1711-1719.
24. Lewis D.A. Antipsychotic medications and brain volume do we have cause for concern?. Arch. Gen. Psychiatry 2011, 68(2):126-127.
25. Lieberman J.A., Tollefson G.D., Charles C., Zipursky R., Sharma T., Kahn R.S., Keefe R.S.E., Green A.I., Gur R.E., McEvoy J., Perkins D., Hamer R.M., Gu H., Tohen M. Antipsychotic drug effects on brain morphology in first-episode psychosis. Arch. Gen. Psychiatry 2005, 62(4):361-370.
26. Menon V., Uddin L.Q. Saliency, switching, attention and control: a network model of insula function. Brain Struct. Funct. 2010, 214:655-667.
27. Mesulam M.M., Mufson E.J. Insula of the old world monkey. III: efferent cortical output and comments on function. J. Comp. Neurol. 1982, 212:38-52.
28. Moncrieff J., Leo J. A systematic review of the effects of antipsychotic drugs on brain volume. Psychol. Med. 2010, 40(9):1409-1422.
29. Morgan K.D., Dazzan P., Orr K.G., Hutchinson G., Chitnis X., Suckling J., et al. Grey matter abnormalities in first-episode schizophrenia and affective psychosis. Br. J. Psychiatry Suppl. 2007, 51:s111-s116.
30. Nelson E.B., Sax K.W., Strakowski S.M. Attentional performance in patients with psychotic and nonpsychotic major depression and schizophrenia. Am. J. Psychiatry 1998, 155:137-139.
31. Overall J.E., Gorham D.E. The brief psychiatric rating scale. Psychol. Rep. 1962, 10:799-812.
32. Pressler M., Nopoulos P., Ho B.C., Andreasen N.C. Insular cortex abnormalities in schizophrenia: relationship to symptoms and typical neuroleptic exposure. Biol. Psychiatry 2005, 57:394-398.
33. Reiss A.L., Hennessey J.G., Rubin M., Beach L., Abrams M.T., Warsofsky I.S., et al. Reliability and validity of an algorithm for fuzzy tissue segmentation of MRI. J. Comput. Assist. Tomogr. 1998, 22:471-479.
34. Schatzberg A.F., Posener J.A., DeBattista C., Kalehzan B.M., Rothschild A.J., Shear P.K. Neuropsychological deficits in psychotic versus nonpsychotic major depression and no mental illness. Am. J. Psychiatry 2000, 157:1095-1100.
35. Schatzberg A.F., Rothschild A.J. Psychotic (delusional) major depression: should it be included as a distinct syndrome in DSM-IV?. Am. J. Psychiatry 1992, 149:733-745.
36. Skaf C.R., Yamada A., Garrido G.E., Buchpiguel C.A., Akamine S., Castro C.C., et al. Psychotic symptoms in major depressive disorder are associated with reduced regional cerebral blood flow in the subgenual anterior cingulate cortex: a voxel-based single photon emission computed tomography (SPECT) study. J. Affect. Disord. 2002, 68:295-305.
37. Sokal R.R., Rohlf F.J. Biometry 1995, WH Freeman and Company, New York. 3rd Ed.
38. Sommer I.E., Diederen K.M., Blom J.D., Willems A., Kushan L., Slotema K., et al. Auditory verbal hallucinations predominantly activate the right inferior frontal area. Brain 2008, 13(12):3169-3177.
39. Takahashi T., Yucel M., Lorenzetti V., Tanino R., Whittle S., Suzuki M., Walterfang M., Pantelis C., Allen N.B. Volumetric MRI study of the insular cortex in individuals with current and past major depression. J. Affect. Disord. 2010, 121(3):231-238.