The p73 G4C14-to-A4T14 polymorphism is associated with risk of lung cancer in the Han nationality of North China

Molecular Carcinogenesis

Volumn 52, Issue 5, 2013, Pages 387-391

  Zhang, Xiaoai ^a   Li, Xu ^b   Wu, Zhihao ^c   Lin, Fangcai ^b   Zhou, Hong ^b  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b BEIJING ELECTRIC POWER HOSPITAL   (China)

^c Gansu Center for Disease Control and Prevention   (China)

Author keywords

Lung cancer; p73 G4C14 to A4T14; Polymorphism; Susceptibility

Indexed keywords

PROTEIN P73;

ADULT; AGED; ARTICLE; CANCER PATIENT; CANCER SUSCEPTIBILITY; CASE CONTROL STUDY; CHINESE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HISTOPATHOLOGY; HUMAN; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SMOKING;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CHINA; DNA-BINDING PROTEINS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LOGISTIC MODELS; LOSS OF HETEROZYGOSITY; LUNG NEOPLASMS; MALE; MIDDLE AGED; NUCLEAR PROTEINS; ODDS RATIO; POLYMORPHISM, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 84876117642     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.21869     Document Type: Article

References (22)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
2. Kaghad M, Bonnet H, Yang A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997; 90: 809-819.
3. Liu JH, Liu CC, Yen CC, Gau JP, Wang WS, Tzeng CH. Pml and TAp73 interacting at nuclear body mediate imatinib-induced p53-independent apoptosis of chronic myeloid leukemia cells. Int J Cancer 2009; 125: 71-77.
4. Tomasini R, Tsuchihara K, Tsuda C, et al. TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity. Proc Natl Acad Sci USA 2009; 106: 797-802.
5. Holcakova J, Ceskova P, Hrstka R, et al. The cell type-specific effect of TAp73 isoforms on the cell cycle and apoptosis. Cell Mol Biol Lett 2008; 13: 404-420.
6. Uramoto H, Sugio K, Oyama T, et al. Expression of the p53 family in lung cancer. Anticancer Res 2006; 26: 1785-1790.
7. Liu K, Zhan M, Zheng P. Loss of p73 expression in six non-small cell lung cancer cell lines is associated with 5'CpG island methylation. Exp Mol Pathol 2008; 84: 59-63.
8. Iacono ML, Monica V, Saviozzi S, et al. p63 and p73 isoform expression in non-small cell lung cancer and corresponding morphological normal lung tissue. J Thorac Oncol 2011; 6: 473-481.
9. Nyman U, Sobczak-Pluta A, Vlachos P, Perlmann T, Zhivotovsky B, Joseph B. Full-length p73alpha represses drug-induced apoptosis in small cell lung carcinoma cells. J Biol Chem 2005; 280: 34159-34169.
10. Shibukawa K, Miyokawa N, Tokusashi Y, Sasaki T, Osanai S, Ohsaki Y. High incidence of chromosomal abnormalities at 1p36 and 9p21 in early-stage central type squamous cell carcinoma and squamous dysplasia of bronchus detected by autofluorescence bronchoscopy. Oncol Rep 2009; 22: 81-87.
11. Li G, Sturgis EM, Wang LE, et al. Association of a p73 exon 2 G4C14-to-A4T14 polymorphism with risk of squamous cell carcinoma of the head and neck. Carcinogenesis 2004; 25: 1911-1916.
12. Niwa Y, Hamajima N, Atsuta Y, et al. Genetic polymorphisms of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro and the risk of cervical cancer in Japanese. Cancer Lett 2004; 205: 55-60.
13. Pfeifer D, Arbman G, Sun XF. Polymorphism of the p73 gene in relation to colorectal cancer risk and survival. Carcinogenesis 2005; 26: 103-107.
14. Misra C, Majumder M, Bajaj S, Ghosh S, Roy B, Roychoudhury S. Polymorphisms at p53, p73, and MDM2 loci modulate the risk of tobacco associated leukoplakia and oral cancer. Mol Carcinog 2009; 48: 790-800.
15. De Feo E, Persiani R, La Greca A, et al. A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression. Mutat Res 2009; 675: 60-65.
16. Chen X, Sturgis EM, Etzel CJ, Wei Q, Li G. p73 G4C14-to-A4T14 polymorphism and risk of human papillomavirus-associated squamous cell carcinoma of the oropharynx in never smokers and never drinkers. Cancer 2008; 113: 3307-3314.
17. Li G, Wang LE, Chamberlain RM, Amos CI, Spitz MR, Wei Q. p73 G4C14-to-A4T14 polymorphism and risk of lung cancer. Cancer Res 2004; 64: 6863-6866.
18. Hu Z, Miao X, Ma H, et al. Dinucleotide polymorphism of p73 gene is associated with a reduced risk of lung cancer in a Chinese population. Int J Cancer 2005; 114: 455-460.
19. Choi JE, Kang HG, Chae MH, et al. No association between p73 G4C14-to-A4T14 polymorphism and the risk of lung cancer in a Korean population. Biochem Genet 2006; 44: 543-550.
20. Hiraki A, Matsuo K, Hamajima N, et al. Different risk relations with smoking for non-small-cell lung cancer: Comparison of TP53 and TP73 genotypes. Asian Pac J Cancer Prev 2003; 4: 107-112.
21. Tomasini R, Tsuchihara K, Wilhelm M, et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev 2008; 22: 2677-2691.
22. Concin N, Becker K, Slade N, et al. Transdominant DeltaTAp73 isoforms are frequently up-regulated in ovarian cancer. Evidence for their role as epigenetic p53 inhibitors in vivo. Cancer Res 2004; 64: 2449-2460.