Are the common genetic variants associated with colorectal cancer risk for DNA mismatch repair gene mutation carriers?

European Journal of Cancer

Volumn 49, Issue 7, 2013, Pages 1578-1587

  Win, Aung Ko ^a   Hopper, John L ^a   Buchanan, Daniel D ^b   Young, Joanne P ^b   Tenesa, Albert ^c,d   Dowty, James G ^a   Giles, Graham G ^e   Goldblatt, Jack ^f   Winship, Ingrid ^g,h   Boussioutas, Alex ^g,i   Young, Graeme P ^j   Parry, Susan ^k,l   Baron, John A ^m   Duggan, David ⁿ   Gallinger, Steven ^o,p   Newcomb, Polly A ^q   Haile, Robert W ^r   Marchand, Loïc Le ^s   Lindor, Noralane M ^t   Jenkins, Mark A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e CANCER EPIDEMIOLOGY CENTRE   (Australia)

^f UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

^h ROYAL MELBOURNE HOSPITAL   (Australia)

ⁱ PETER MACCALLUM CANCER CENTRE   (Australia)

^j FLINDERS UNIVERSITY   (Australia)

^k AUCKLAND CITY HOSPITAL   (New Zealand)

^l MIDDLEMORE HOSPITAL   (New Zealand)

^m UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

ⁿ TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^o MOUNT SINAI HOSPITAL   (Canada)

^p CANCER CARE ONTARIO   (Canada)

^q Fred Hutchinson Cancer Research Center   (United States)

^r UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^s UNIVERSITY OF HAWAII   (United States)

^t MAYO CLINIC   (United States)

more..

Author keywords

Colorectal cancer; Genetic variant; Lynch syndrome; Mismatch repair

Indexed keywords

MISMATCH REPAIR PROTEIN PMS2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER RISK; COLORECTAL CANCER; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ADULT; ALLELES; COLORECTAL NEOPLASMS; DNA MISMATCH REPAIR; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; FAMILY HEALTH; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GERM-LINE MUTATION; HETEROZYGOTE; HUMANS; MALE; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; RISK FACTORS;

EID: 84876116506     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2013.01.029     Document Type: Article

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