메뉴 건너뛰기




Volumn 3, Issue 2, 2013, Pages 245-259

Current state and future prospects of pharmacological interventions for autism

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ARIPIPRAZOLE; CITALOPRAM; CLOMIPRAMINE; CLOZAPINE; CYCLOSERINE; DESIPRAMINE; DONEPEZIL; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; GALANTAMINE; HALOPERIDOL; LAMOTRIGINE; LITHIUM; MEMANTINE; MIRTAZAPINE; OLANZAPINE; PALIPERIDONE; PAROXETINE; PLACEBO; QUETIAPINE; RISPERIDONE; RIVASTIGMINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; UNINDEXED DRUG; VALPROATE SEMISODIUM; VENLAFAXINE; ZIPRASIDONE;

EID: 84876110481     PISSN: 17582008     EISSN: 17582016     Source Type: Journal    
DOI: 10.2217/npy.13.22     Document Type: Review
Times cited : (3)

References (97)
  • 1
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association. Task Force on DSM-IV (4th Edition). American Psychiatric Association, DC, USA
    • American Psychiatric Association. Task Force on DSM-IV. In: Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR (4th Edition). American Psychiatric Association, DC, USA (2000).
    • (2000) Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR
  • 2
    • 35048859960 scopus 로고    scopus 로고
    • Risperidone approved for the treatment of serious behavioral problems in children with autism
    • Scahill L, Koenig K, Carroll DH, Pachler M. Risperidone approved for the treatment of serious behavioral problems in children with autism. J. Child Adolesc. Psychiatr Nurs. 20(3), 188-190 (2007).
    • (2007) J. Child Adolesc. Psychiatr Nurs. , vol.20 , Issue.3 , pp. 188-190
    • Scahill, L.1    Koenig, K.2    Carroll, D.H.3    Pachler, M.4
  • 3
    • 71949121464 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder
    • Owen R, Sikich L, Marcus RN, et al. Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder. Pediatrics 124(6), 1533-1540 (2009).
    • (2009) Pediatrics , vol.124 , Issue.6 , pp. 1533-1540
    • Owen, R.1    Sikich, L.2    Marcus, R.N.3
  • 4
    • 40949152478 scopus 로고    scopus 로고
    • Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders
    • Mandell DS, Morales KH, Marcus SC, Stahmer AC, Doshi J, Polsky DE. Psychotropic medication use among Medicaid-enrolled children with autism spectrum disorders. Pediatrics 121(3), e441-e448 (2008).
    • (2008) Pediatrics , vol.121 , Issue.3
    • Mandell, D.S.1    Morales, K.H.2    Marcus, S.C.3    Stahmer, A.C.4    Doshi, J.5    Polsky, D.E.6
  • 5
    • 69049086568 scopus 로고    scopus 로고
    • A longitudinal investigation of psychotropic and non-psychotropic medication use among adolescents and adults with autism spectrum disorders
    • Esbensen AJ, Greenberg JS, Seltzer MM, Aman MG. A longitudinal investigation of psychotropic and non-psychotropic medication use among adolescents and adults with autism spectrum disorders. J. Autism Dev. Disord. 39(9), 1339-1349 (2009).
    • (2009) J. Autism Dev. Disord. , vol.39 , Issue.9 , pp. 1339-1349
    • Esbensen, A.J.1    Greenberg, J.S.2    Seltzer, M.M.3    Aman, M.G.4
  • 6
    • 0028793248 scopus 로고
    • The Aberrant Behavior Checklist -Community: Factor validity and effect of subject variables for adults in group homes
    • Aman MG, Burrow WH, Wolford PL. The Aberrant Behavior Checklist -Community: factor validity and effect of subject variables for adults in group homes. Am. J. Ment. Retard. 100(3), 283-292 (1995).
    • (1995) Am. J. Ment. Retard. , vol.100 , Issue.3 , pp. 283-292
    • Aman, M.G.1    Burrow, W.H.2    Wolford, P.L.3
  • 9
    • 0036682267 scopus 로고    scopus 로고
    • Risperidone in children with autism and serious behavioral problems
    • Mccracken JT, Mcgough J, Shah B, et al. Risperidone in children with autism and serious behavioral problems. N. Engl. J. Med. 347(5), 314-321 (2002).
    • (2002) N. Engl. J. Med. , vol.347 , Issue.5 , pp. 314-321
    • McCracken, J.T.1    McGough, J.2    Shah, B.3
  • 10
    • 16644370679 scopus 로고    scopus 로고
    • Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders
    • Shea S, Turgay A, Carroll A, et al. Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders. Pediatrics 114(5), e634-e641 (2004).
    • (2004) Pediatrics , vol.114 , Issue.5
    • Shea, S.1    Turgay, A.2    Carroll, A.3
  • 11
    • 20044374710 scopus 로고    scopus 로고
    • Risperidone for the core symptom domains of autism: Results from the study by the autism network of the research units on pediatric psychopharmacology
    • McDougle CJ, Scahill L, Aman MG, et al. Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. Am. J. Psychiatry 162(6), 1142-1148 (2005).
    • (2005) Am. J. Psychiatry , vol.162 , Issue.6 , pp. 1142-1148
    • McDougle, C.J.1    Scahill, L.2    Aman, M.G.3
  • 12
    • 0031855086 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders
    • McDougle CJ, Holmes JP, Carlson DC, Pelton GH, Cohen DJ, Price LH. A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders. Arch. Gen. Psychiatry 55(7), 633-641 (1998).
    • (1998) Arch. Gen. Psychiatry , vol.55 , Issue.7 , pp. 633-641
    • McDougle, C.J.1    Holmes, J.P.2    Carlson, D.C.3    Pelton, G.H.4    Cohen, D.J.5    Price, L.H.6
  • 13
    • 29944444165 scopus 로고    scopus 로고
    • Acute and long-term safety and tolerability of risperidone in children with autism
    • Aman MG, Arnold LE, McDougle CJ, et al. Acute and long-term safety and tolerability of risperidone in children with autism. J. Child Adolesc. Psychopharmacol. 15(6), 869-884 (2005).
    • (2005) J. Child Adolesc. Psychopharmacol. , vol.15 , Issue.6 , pp. 869-884
    • Aman, M.G.1    Arnold, L.E.2    McDougle, C.J.3
  • 14
    • 71449095638 scopus 로고    scopus 로고
    • A placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder
    • Marcus RN, Owen R, Kamen L, et al. A placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder. J. Am. Acad. Child Adolesc. Psychiatry 48(11), 1110-1119 (2009).
    • (2009) J. Am. Acad. Child Adolesc. Psychiatry , vol.48 , Issue.11 , pp. 1110-1119
    • Marcus, R.N.1    Owen, R.2    Kamen, L.3
  • 15
    • 8144220313 scopus 로고    scopus 로고
    • Aripiprazole for maladaptive behavior in pervasive developmental disorders
    • Stigler K A, Posey DJ, McDougle CJ. Aripiprazole for maladaptive behavior in pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 14(3), 455-463 (2004).
    • (2004) J. Child Adolesc. Psychopharmacol. , vol.14 , Issue.3 , pp. 455-463
    • Stigler, K.A.1    Posey, D.J.2    McDougle, C.J.3
  • 16
    • 67650895041 scopus 로고    scopus 로고
    • Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: A 14-week, prospective, open-label study
    • Stigler KA, Diener JT, Kohn AE, et al. Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: a 14-week, prospective, open-label study. J. Child Adolesc. Psychopharmacol. 19(3), 265-274 (2009).
    • (2009) J. Child Adolesc. Psychopharmacol. , vol.19 , Issue.3 , pp. 265-274
    • Stigler, K.A.1    Diener, J.T.2    Kohn, A.E.3
  • 17
    • 79958786682 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of irritability in pediatric patients (aged 6-17 years) with autistic disorder: Results from a 52-week, open-label study
    • Marcus RN, Owen R, Manos G, et al. Aripiprazole in the treatment of irritability in pediatric patients (aged 6-17 years) with autistic disorder: results from a 52-week, open-label study. J. Child Adolesc. Psychopharmacol. 21(3), 229-236 (2011).
    • (2011) J. Child Adolesc. Psychopharmacol. , vol.21 , Issue.3 , pp. 229-236
    • Marcus, R.N.1    Owen, R.2    Manos, G.3
  • 18
    • 80052989828 scopus 로고    scopus 로고
    • Safety and tolerability of aripiprazole for irritability in pediatric patients with autistic disorder: A 52-week, open-label, multicenter study
    • Marcus RN, Owen R, Manos G, et al. Safety and tolerability of aripiprazole for irritability in pediatric patients with autistic disorder: a 52-week, open-label, multicenter study. J. Clin. Psychiatry 72(9), 1270-1276 (2011).
    • (2011) J. Clin. Psychiatry , vol.72 , Issue.9 , pp. 1270-1276
    • Marcus, R.N.1    Owen, R.2    Manos, G.3
  • 19
    • 84866738145 scopus 로고    scopus 로고
    • Aripiprazole in the treatment of challenging behaviour in adults with autism spectrum disorder
    • Jordan I, Robertson D, Catani M, Craig M, Murphy D. Aripiprazole in the treatment of challenging behaviour in adults with autism spectrum disorder. Psychopharmacology 223(3), 357-360 (2012).
    • (2012) Psychopharmacology , vol.223 , Issue.3 , pp. 357-360
    • Jordan, I.1    Robertson, D.2    Catani, M.3    Craig, M.4    Murphy, D.5
  • 21
  • 23
    • 81955164235 scopus 로고    scopus 로고
    • Low-dose quetiapine for adolescents with autistic spectrum disorder and aggressive behavior: Open-label trial
    • Golubchik P, Sever J, Weizman A. Low-dose quetiapine for adolescents with autistic spectrum disorder and aggressive behavior: open-label trial. Clin. Neuropharmacol. 34(6), 216-219 (2011).
    • (2011) Clin. Neuropharmacol. , vol.34 , Issue.6 , pp. 216-219
    • Golubchik, P.1    Sever, J.2    Weizman, A.3
  • 24
    • 23744480565 scopus 로고    scopus 로고
    • Retrospective study of quetiapine in children and adolescents with pervasive developmental disorders
    • Hardan AY, Jou RJ, Handen BL. Retrospective study of quetiapine in children and adolescents with pervasive developmental disorders. J. Autism Dev. Disord. 35(3), 387-391 (2005).
    • (2005) J. Autism Dev. Disord. , vol.35 , Issue.3 , pp. 387-391
    • Hardan, A.Y.1    Jou, R.J.2    Handen, B.L.3
  • 25
    • 33750952522 scopus 로고    scopus 로고
    • A double-blind placebo-controlled pilot study of olanzapine in childhood/adolescent pervasive developmental disorder
    • Hollander E, Wasserman S, Swanson EN, et al. A double-blind placebo-controlled pilot study of olanzapine in childhood/adolescent pervasive developmental disorder. J. Child Adolesc. Psychopharmacol. 16(5), 541-548 (2006).
    • (2006) J. Child Adolesc. Psychopharmacol. , vol.16 , Issue.5 , pp. 541-548
    • Hollander, E.1    Wasserman, S.2    Swanson, E.N.3
  • 26
    • 49449095339 scopus 로고    scopus 로고
    • Olanzapine in the treatment of behavioral problems associated with autism: An open-label trial in Kuwait
    • Fido A, Al-Saad S. Olanzapine in the treatment of behavioral problems associated with autism: an open-label trial in Kuwait. Med. Princ. Pract. 17(5), 415-418 (2008).
    • (2008) Med. Princ. Pract. , vol.17 , Issue.5 , pp. 415-418
    • Fido, A.1    Al-Saad, S.2
  • 27
    • 0033071543 scopus 로고    scopus 로고
    • Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: An open-label pilot study
    • Potenza MN, Holmes JP, Kanes SJ, McDougle CJ. Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: an open-label pilot study. J. Clin. Psychopharmacol. 19(1), 37-44 (1999).
    • (1999) J. Clin. Psychopharmacol. , vol.19 , Issue.1 , pp. 37-44
    • Potenza, M.N.1    Holmes, J.P.2    Kanes, S.J.3    McDougle, C.J.4
  • 28
    • 1442284523 scopus 로고    scopus 로고
    • The effect of a switch to ziprasidone in an adult population with autistic disorder: Chart review of naturalistic, open-label treatment
    • Cohen SA, Fitzgerald BJ, Khan SR, Khan A. The effect of a switch to ziprasidone in an adult population with autistic disorder: chart review of naturalistic, open-label treatment. J. Clin. Psychiatry 65(1), 110-113 (2004).
    • (2004) J. Clin. Psychiatry , vol.65 , Issue.1 , pp. 110-113
    • Cohen, S.A.1    Fitzgerald, B.J.2    Khan, S.R.3    Khan, A.4
  • 30
    • 0036674389 scopus 로고    scopus 로고
    • Case series: Use of ziprasidone for maladaptive symptoms in youths with autism
    • McDougle CJ, Kem DL, Posey DJ. Case series: use of ziprasidone for maladaptive symptoms in youths with autism. J. Am. Acad. Child Adolesc. Psychiatry 41(8), 921-927 (2002).
    • (2002) J. Am. Acad. Child Adolesc. Psychiatry , vol.41 , Issue.8 , pp. 921-927
    • McDougle, C.J.1    Kem, D.L.2    Posey, D.J.3
  • 31
    • 79955600656 scopus 로고    scopus 로고
    • Retrospective review of clozapine in the treatment of patients with autism spectrum disorder and severe disruptive behaviors
    • Beherec L, Lambrey S, Quilici G, Rosier A, Falissard B, Guillin O. Retrospective review of clozapine in the treatment of patients with autism spectrum disorder and severe disruptive behaviors. J. Clin. Psychopharmacol. 31(3), 341-344 (2011).
    • (2011) J. Clin. Psychopharmacol. , vol.31 , Issue.3 , pp. 341-344
    • Beherec, L.1    Lambrey, S.2    Quilici, G.3    Rosier, A.4    Falissard, B.5    Guillin, O.6
  • 32
    • 80054803302 scopus 로고    scopus 로고
    • Epilepsy and autism: Neurodevelopmental perspective
    • Tuchman R, Cuccaro M. Epilepsy and autism: neurodevelopmental perspective. Curr. Neurol. Neurosci. Rep. 11(4), 428-434 (2011).
    • (2011) Curr. Neurol. Neurosci. Rep. , vol.11 , Issue.4 , pp. 428-434
    • Tuchman, R.1    Cuccaro, M.2
  • 33
    • 80052469389 scopus 로고    scopus 로고
    • A pilot study to improve venipuncture compliance in children and adolescents with autism spectrum disorders
    • Davit CJ, Hundley RJ, Bacic JD, Hanson EM. A pilot study to improve venipuncture compliance in children and adolescents with autism spectrum disorders. J. Dev. Behav. Pediatr. 32(7), 521-525 (2011).
    • (2011) J. Dev. Behav. Pediatr. , vol.32 , Issue.7 , pp. 521-525
    • Davit, C.J.1    Hundley, R.J.2    Bacic, J.D.3    Hanson, E.M.4
  • 34
    • 0018045453 scopus 로고
    • A comparison of haloperidol and behavior therapy and their interaction in autistic children
    • Campbell M, Anderson LT, Meier M, et al. A comparison of haloperidol and behavior therapy and their interaction in autistic children. J. Am. Acad. Child Psychiatry 17(4), 640-655 (1978).
    • (1978) J. Am. Acad. Child Psychiatry , vol.17 , Issue.4 , pp. 640-655
    • Campbell, M.1    Anderson, L.T.2    Meier, M.3
  • 35
    • 0034916963 scopus 로고    scopus 로고
    • Clomipramine versus haloperidol in the treatment of autistic disorder: A double-blind, placebo-controlled, crossover study
    • Remington G, Sloman L, Konstantareas M, Parker K, Gow R. Clomipramine versus haloperidol in the treatment of autistic disorder: a double-blind, placebo-controlled, crossover study. J. Clin. Psychopharmacol. 21(4), 440-444 (2001).
    • (2001) J. Clin. Psychopharmacol. , vol.21 , Issue.4 , pp. 440-444
    • Remington, G.1    Sloman, L.2    Konstantareas, M.3    Parker, K.4    Gow, R.5
  • 37
    • 65849434082 scopus 로고    scopus 로고
    • Executive function deficits and neural discordance in children with autism spectrum disorders
    • Chan AS, Cheung MC, Han YM, et al. Executive function deficits and neural discordance in children with autism spectrum disorders. Clin. Neurophysiol. 120(6), 1107-1115 (2009).
    • (2009) Clin. Neurophysiol. , vol.120 , Issue.6 , pp. 1107-1115
    • Chan, A.S.1    Cheung, M.C.2    Han, Y.M.3
  • 38
    • 0034946403 scopus 로고    scopus 로고
    • Cholinergic activity in autism: Abnormalities in the cerebral cortex and basal forebrain
    • Perry EK, Lee ML, Martin-Ruiz CM, et al. Cholinergic activity in autism: abnormalities in the cerebral cortex and basal forebrain. Am. J. Psychiatry 158(7), 1058-1066 (2001).
    • (2001) Am. J. Psychiatry , vol.158 , Issue.7 , pp. 1058-1066
    • Perry, E.K.1    Lee, M.L.2    Martin-Ruiz, C.M.3
  • 39
    • 0001655596 scopus 로고    scopus 로고
    • Donepezil use in children with autistic spectrum disorders
    • Chez MG, Nowinski CV, Buchanan CP. Donepezil use in children with autistic spectrum disorders. Ann. Neurol. 48, 541 (2000).
    • (2000) Ann. Neurol. , vol.48 , pp. 541
    • Chez, M.G.1    Nowinski, C.V.2    Buchanan, C.P.3
  • 41
    • 2342436849 scopus 로고    scopus 로고
    • Treating autistic spectrum disorders in children: Utility of the cholinesterase inhibitor rivastigmine tartrate
    • Chez MG, Aimonovitch M, Buchanan T, Mrazek S, Tremb RJ. Treating autistic spectrum disorders in children: utility of the cholinesterase inhibitor rivastigmine tartrate. J. Child Neurol. 19(3), 165-169 (2004).
    • (2004) J. Child Neurol. , vol.19 , Issue.3 , pp. 165-169
    • Chez, M.G.1    Aimonovitch, M.2    Buchanan, T.3    Mrazek, S.4    Tremb, R.J.5
  • 42
  • 43
    • 85047699588 scopus 로고    scopus 로고
    • Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: An in vivo SPECT study
    • Murphy DG, Daly E, Schmitz N, et al. Cortical serotonin 5-HT2A receptor binding and social communication in adults with Asperger's syndrome: an in vivo SPECT study. Am. J. Psychiatry 163(5), 934-936 (2006).
    • (2006) Am. J. Psychiatry , vol.163 , Issue.5 , pp. 934-936
    • Murphy, D.G.1    Daly, E.2    Schmitz, N.3
  • 44
    • 0032987647 scopus 로고    scopus 로고
    • Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children
    • Chugani DC, Muzik O, Behen M, et al. Developmental changes in brain serotonin synthesis capacity in autistic and nonautistic children. Ann. Neurol. 45(3), 287-295 (1999).
    • (1999) Ann. Neurol. , vol.45 , Issue.3 , pp. 287-295
    • Chugani, D.C.1    Muzik, O.2    Behen, M.3
  • 45
    • 0000526929 scopus 로고
    • Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children
    • Schain RJ, Freedman DX. Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children. J. Pediatr. 58, 315-320 (1961).
    • (1961) J. Pediatr. , vol.58 , pp. 315-320
    • Schain, R.J.1    Freedman, D.X.2
  • 47
    • 0031565115 scopus 로고    scopus 로고
    • Pharmacological profile of antidepressants and related compounds at human monoamine transporters
    • Tatsumi M, Groshan K, Blakely RD, Richelson E. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur. J. Pharmacol. 340(2-3), 249-258 (1997).
    • (1997) Eur. J. Pharmacol. , vol.340 , Issue.2-3 , pp. 249-258
    • Tatsumi, M.1    Groshan, K.2    Blakely, R.D.3    Richelson, E.4
  • 48
    • 0027158571 scopus 로고
    • A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder
    • Gordon CT, State RC, Nelson JE, Hamburger SD, Rapoport JL. A double-blind comparison of clomipramine, desipramine, and placebo in the treatment of autistic disorder. Arch. Gen. Psychiatry 50(6), 441-447 (1993).
    • (1993) Arch. Gen. Psychiatry , vol.50 , Issue.6 , pp. 441-447
    • Gordon, C.T.1    State, R.C.2    Nelson, J.E.3    Hamburger, S.D.4    Rapoport, J.L.5
  • 51
    • 0036751586 scopus 로고    scopus 로고
    • A retrospective assessment of citalopram in children and adolescents with pervasive developmental disorders
    • Couturier JL, Nicolson R. A retrospective assessment of citalopram in children and adolescents with pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 12(3), 243-248 (2002).
    • (2002) J. Child Adolesc. Psychopharmacol. , vol.12 , Issue.3 , pp. 243-248
    • Couturier, J.L.1    Nicolson, R.2
  • 52
    • 66449098701 scopus 로고    scopus 로고
    • Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: Citalopram ineffective in children with autism
    • STAART Psychopharmacology Network
    • King BH, Hollander E, Sikich L, et al.; STAART Psychopharmacology Network. Lack of efficacy of citalopram in children with autism spectrum disorders and high levels of repetitive behavior: citalopram ineffective in children with autism. Arch. Gen. Psychiatry. 66(6), 583-590 (2009).
    • (2009) Arch. Gen. Psychiatry. , vol.66 , Issue.6 , pp. 583-590
    • King, B.H.1    Hollander, E.2    Sikich, L.3
  • 53
    • 15344341046 scopus 로고    scopus 로고
    • An open-label trial of escitalopram in pervasive developmental disorders
    • Owley T, Walton L, Salt J, et al. An open-label trial of escitalopram in pervasive developmental disorders. J. Am. Acad. Child Adolesc. Psychiatry 44(4), 343-348 (2005).
    • (2005) J. Am. Acad. Child Adolesc. Psychiatry , vol.44 , Issue.4 , pp. 343-348
    • Owley, T.1    Walton, L.2    Salt, J.3
  • 54
    • 13944264748 scopus 로고    scopus 로고
    • A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism
    • Hollander E, Phillips A, Chaplin W, et al. A placebo controlled crossover trial of liquid fluoxetine on repetitive behaviors in childhood and adolescent autism. Neuropsychopharmacology 30(3), 582-589 (2005).
    • (2005) Neuropsychopharmacology , vol.30 , Issue.3 , pp. 582-589
    • Hollander, E.1    Phillips, A.2    Chaplin, W.3
  • 55
    • 84858971972 scopus 로고    scopus 로고
    • A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders
    • Hollander E, Soorya L, Chaplin W, et al. A double-blind placebo-controlled trial of fluoxetine for repetitive behaviors and global severity in adult autism spectrum disorders. Am. J. Psychiatry 169(3), 292-299 (2012).
    • (2012) Am. J. Psychiatry , vol.169 , Issue.3 , pp. 292-299
    • Hollander, E.1    Soorya, L.2    Chaplin, W.3
  • 58
    • 23744453194 scopus 로고    scopus 로고
    • Clinical efficacy of fluvoxamine and functional polymorphism in a serotonin transporter gene on childhood autism
    • Sugie Y, Sugie H, Fukuda T, et al. Clinical efficacy of fluvoxamine and functional polymorphism in a serotonin transporter gene on childhood autism. J. Autism Dev. Disord. 35(3), 377-385 (2005).
    • (2005) J. Autism Dev. Disord. , vol.35 , Issue.3 , pp. 377-385
    • Sugie, Y.1    Sugie, H.2    Fukuda, T.3
  • 59
    • 0033746434 scopus 로고    scopus 로고
    • Repetitive thoughts and behavior in pervasive developmental disorders: Treatment with serotonin reuptake inhibitors
    • McDougle CJ, Kresch LE, Posey DJ. Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors. J. Autism Dev. Disord. 30(5), 427-435 (2000).
    • (2000) J. Autism Dev. Disord. , vol.30 , Issue.5 , pp. 427-435
    • McDougle, C.J.1    Kresch, L.E.2    Posey, D.J.3
  • 60
    • 0037298453 scopus 로고    scopus 로고
    • Low-dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: A prospective, open-label study
    • Martin A, Koenig K, Anderson GM, Scahill L. Low-dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: a prospective, open-label study. J. Autism Dev. Disord. 33(1), 77-85 (2003).
    • (2003) J. Autism Dev. Disord. , vol.33 , Issue.1 , pp. 77-85
    • Martin, A.1    Koenig, K.2    Anderson, G.M.3    Scahill, L.4
  • 63
    • 0031938137 scopus 로고    scopus 로고
    • Paroxetine treatment of aggression and self-injury in persons with mental retardation
    • Davanzo PA, Belin TR, Widawski MH, King BH. Paroxetine treatment of aggression and self-injury in persons with mental retardation. Am. J. Ment. Retard. 102(5), 427-437 (1998).
    • (1998) Am. J. Ment. Retard. , vol.102 , Issue.5 , pp. 427-437
    • Davanzo, P.A.1    Belin, T.R.2    Widawski, M.H.3    King, B.H.4
  • 64
    • 65249176803 scopus 로고    scopus 로고
    • Effectiveness of mirtazapine in the treatment of inappropriate sexual behaviors in individuals with autistic disorder
    • Coskun M, Karakoc S, Kircelli F, Mukaddes NM. Effectiveness of mirtazapine in the treatment of inappropriate sexual behaviors in individuals with autistic disorder. J. Child Adolesc. Psychopharmacol. 19(2), 203-206 (2009).
    • (2009) J. Child Adolesc. Psychopharmacol. , vol.19 , Issue.2 , pp. 203-206
    • Coskun, M.1    Karakoc, S.2    Kircelli, F.3    Mukaddes, N.M.4
  • 65
    • 0034797067 scopus 로고    scopus 로고
    • A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders
    • Posey DJ, Guenin KD, Kohn AE, Swiezy NB, McDougle CJ. A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 11(3), 267-277 (2001).
    • (2001) J. Child Adolesc. Psychopharmacol. , vol.11 , Issue.3 , pp. 267-277
    • Posey, D.J.1    Guenin, K.D.2    Kohn, A.E.3    Swiezy, N.B.4    McDougle, C.J.5
  • 66
    • 33344472157 scopus 로고    scopus 로고
    • Low-dose venlafaxine in three adolescents and young adults with autistic disorder improves self-injurious behavior and attention deficit/ hyperactivity disorders (ADHD)-like symptoms
    • Carminati GG, Deriaz N, Bertschy G. Low-dose venlafaxine in three adolescents and young adults with autistic disorder improves self-injurious behavior and attention deficit/ hyperactivity disorders (ADHD)-like symptoms. Prog. Neuropsychopharmacol. Biol. Psychiatry 30(2), 312-315 (2006).
    • (2006) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.30 , Issue.2 , pp. 312-315
    • Carminati, G.G.1    Deriaz, N.2    Bertschy, G.3
  • 68
    • 0034053491 scopus 로고    scopus 로고
    • Venlafaxine in children, adolescents, and young adults with autism spectrum disorders: An open retrospective clinical report
    • Hollander E, Kaplan A, Cartwright C, Reichman D. Venlafaxine in children, adolescents, and young adults with autism spectrum disorders: an open retrospective clinical report. J. Child Neurol. 15(2), 132-135 (2000).
    • (2000) J. Child Neurol. , vol.15 , Issue.2 , pp. 132-135
    • Hollander, E.1    Kaplan, A.2    Cartwright, C.3    Reichman, D.4
  • 69
    • 76749085678 scopus 로고    scopus 로고
    • Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders
    • Hollander E, Chaplin W, Soorya L, et al. Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders. Neuropsychopharmacology 35(4), 990-998 (2010).
    • (2010) Neuropsychopharmacology , vol.35 , Issue.4 , pp. 990-998
    • Hollander, E.1    Chaplin, W.2    Soorya, L.3
  • 71
    • 26444497982 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of valproate for aggression in youth with pervasive developmental disorders
    • Hellings JA, Weckbaugh M, Nickel EJ, et al. A double-blind, placebo-controlled study of valproate for aggression in youth with pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 15(4), 682-692 (2005).
    • (2005) J. Child Adolesc. Psychopharmacol. , vol.15 , Issue.4 , pp. 682-692
    • Hellings, J.A.1    Weckbaugh, M.2    Nickel, E.J.3
  • 72
    • 0028126802 scopus 로고
    • Lithium augmentation of fluvoxamine in autistic disorder: A case report
    • Epperson CN, McDougle CJ, Anand A, et al. Lithium augmentation of fluvoxamine in autistic disorder: a case report. J. Child Adolesc. Psychopharmacol. 4(3), 201-207 (1994).
    • (1994) J. Child Adolesc. Psychopharmacol. , vol.4 , Issue.3 , pp. 201-207
    • Epperson, C.N.1    McDougle, C.J.2    Anand, A.3
  • 73
    • 0023522731 scopus 로고
    • Lithium responsive manic-like symptoms in two individuals with autism and mental retardation
    • Steingard R, Biederman J. Lithium responsive manic-like symptoms in two individuals with autism and mental retardation. J. Am. Acad. Child Adolesc. Psychiatry 26(6), 932-935 (1987).
    • (1987) J. Am. Acad. Child Adolesc. Psychiatry , vol.26 , Issue.6 , pp. 932-935
    • Steingard, R.1    Biederman, J.2
  • 74
    • 0035321893 scopus 로고    scopus 로고
    • Lamotrigine therapy for autistic disorder: A randomized, double-blind, placebo-controlled trial
    • Belsito KM, Law PA, Kirk KS, Landa RJ, Zimmerman AW. Lamotrigine therapy for autistic disorder: a randomized, double-blind, placebo-controlled trial. J. Autism Dev. Disord. 31(2), 175-181 (2001).
    • (2001) J. Autism Dev. Disord. , vol.31 , Issue.2 , pp. 175-181
    • Belsito, K.M.1    Law, P.A.2    Kirk, K.S.3    Landa, R.J.4    Zimmerman, A.W.5
  • 75
    • 0028598399 scopus 로고
    • Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits
    • Uvebrant P, Bauziene R. Intractable epilepsy in children. The efficacy of lamotrigine treatment, including non-seizure-related benefits. Neuropediatrics 25(6), 284-289 (1994).
    • (1994) Neuropediatrics , vol.25 , Issue.6 , pp. 284-289
    • Uvebrant, P.1    Bauziene, R.2
  • 76
    • 84861096785 scopus 로고    scopus 로고
    • A randomized placebo-controlled trial of d-cycloserine to enhance exposure therapy for posttraumatic stress disorder
    • De Kleine R A, Hendriks GJ, Kusters WJ, Broekman TG, Van Minnen A. A randomized placebo-controlled trial of d-cycloserine to enhance exposure therapy for posttraumatic stress disorder. Biol. Psychiatry 71(11), 962-968 (2012).
    • (2012) Biol. Psychiatry , vol.71 , Issue.11 , pp. 962-968
    • De Kleine, R.A.1    Hendriks, G.J.2    Kusters, W.J.3    Broekman, T.G.4    Van Minnen, A.5
  • 77
    • 33644755641 scopus 로고    scopus 로고
    • Augmentation of exposure therapy with d-cycloserine for social anxiety disorder
    • Hofmann SG, Meuret AE, Smits JA, et al. Augmentation of exposure therapy with d-cycloserine for social anxiety disorder. Arch. Gen. Psychiatry 63(3), 298-304 (2006).
    • (2006) Arch. Gen. Psychiatry , vol.63 , Issue.3 , pp. 298-304
    • Hofmann, S.G.1    Meuret, A.E.2    Smits, J.A.3
  • 78
    • 42449140233 scopus 로고    scopus 로고
    • Augmentation of behavior therapy with d-cycloserine for obsessive-compulsive disorder
    • quiz 409
    • Wilhelm S, Buhlmann U, Tolin DF, et al. Augmentation of behavior therapy with d-cycloserine for obsessive-compulsive disorder. Am. J. Psychiatry 165(3), 335-341; quiz 409 (2008).
    • (2008) Am. J. Psychiatry , vol.165 , Issue.3 , pp. 335-341
    • Wilhelm, S.1    Buhlmann, U.2    Tolin, D.F.3
  • 80
  • 81
    • 33750950870 scopus 로고    scopus 로고
    • A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders
    • Owley T, Salt J, Guter S, et al. A prospective, open-label trial of memantine in the treatment of cognitive, behavioral, and memory dysfunction in pervasive developmental disorders. J. Child Adolesc. Psychopharmacol. 16(5), 517-524 (2006).
    • (2006) J. Child Adolesc. Psychopharmacol. , vol.16 , Issue.5 , pp. 517-524
    • Owley, T.1    Salt, J.2    Guter, S.3
  • 82
    • 0036832316 scopus 로고    scopus 로고
    • Genetics of childhood disorders: XLIV. autism, part 3: Psychopharmacology of autism
    • McDougle CJ, Posey D. Genetics of childhood disorders: XLIV. autism, part 3: psychopharmacology of autism. J. Am. Acad. Child Adolesc. Psychiatry 41(11), 1380-1383 (2002).
    • (2002) J. Am. Acad. Child Adolesc. Psychiatry , vol.41 , Issue.11 , pp. 1380-1383
    • McDougle, C.J.1    Posey, D.2
  • 83
    • 3342976049 scopus 로고    scopus 로고
    • Methylphenidate for pervasive developmental disorders: Safety and efficacy of acute single dose test and ongoing therapy: An open-pilot study
    • Di Martino A, Melis G, Cianchetti C, Zuddas A. Methylphenidate for pervasive developmental disorders: safety and efficacy of acute single dose test and ongoing therapy: an open-pilot study. J. Child Adolesc. Psychopharmacol. 14(2), 207-218 (2004).
    • (2004) J. Child Adolesc. Psychopharmacol. , vol.14 , Issue.2 , pp. 207-218
    • Di Martino, A.1    Melis, G.2    Cianchetti, C.3    Zuddas, A.4
  • 84
    • 3042858920 scopus 로고    scopus 로고
    • Autism spectrum disorders in children with normal intellectual levels: Associated impairments and subgroups
    • Sturm H, Fernell E, Gillberg C. Autism spectrum disorders in children with normal intellectual levels: associated impairments and subgroups. Dev. Med. Child Neurol. 46(7), 444-447 (2004).
    • (2004) Dev. Med. Child Neurol. , vol.46 , Issue.7 , pp. 444-447
    • Sturm, H.1    Fernell, E.2    Gillberg, C.3
  • 85
    • 3042704670 scopus 로고    scopus 로고
    • The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: Results of a retrospective chart review
    • Goldstein S, Schwebach AJ. The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: results of a retrospective chart review. J. Autism Dev. Disord. 34(3), 329-339 (2004).
    • (2004) J. Autism Dev. Disord. , vol.34 , Issue.3 , pp. 329-339
    • Goldstein, S.1    Schwebach, A.J.2
  • 86
    • 0028998160 scopus 로고
    • Use of methylphenidate in the treatment of children with autistic disorder
    • Quintana H, Birmaher B, Stedge D, et al. Use of methylphenidate in the treatment of children with autistic disorder. J. Autism Dev. Disord. 25(3), 283-294 (1995).
    • (1995) J. Autism Dev. Disord. , vol.25 , Issue.3 , pp. 283-294
    • Quintana, H.1    Birmaher, B.2    Stedge, D.3
  • 87
    • 0033798312 scopus 로고    scopus 로고
    • Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder
    • Handen BL, Johnson CR, Lubetsky M. Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder. J. Autism Dev. Disord. 30(3), 245-255 (2000).
    • (2000) J. Autism Dev. Disord. , vol.30 , Issue.3 , pp. 245-255
    • Handen, B.L.1    Johnson, C.R.2    Lubetsky, M.3
  • 91
    • 0032519523 scopus 로고    scopus 로고
    • Plasma oxytocin levels in autistic children
    • Modahl C, Green L, Fein D, et al. Plasma oxytocin levels in autistic children. Biol. Psychiatry 43(4), 270-277 (1998).
    • (1998) Biol. Psychiatry , vol.43 , Issue.4 , pp. 270-277
    • Modahl, C.1    Green, L.2    Fein, D.3
  • 92
    • 77949486670 scopus 로고    scopus 로고
    • Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders
    • Guastella AJ, Einfeld SL, Gray KM, et al. Intranasal oxytocin improves emotion recognition for youth with autism spectrum disorders. Biol. Psychiatry 67(7), 692-694 (2010).
    • (2010) Biol. Psychiatry , vol.67 , Issue.7 , pp. 692-694
    • Guastella, A.J.1    Einfeld, S.L.2    Gray, K.M.3
  • 93
    • 79551594543 scopus 로고    scopus 로고
    • Toward fulfilling the promise of molecular medicine in fragile X syndrome
    • Krueger DD, Bear MF. Toward fulfilling the promise of molecular medicine in fragile X syndrome. Ann. Rev. Med. 62, 411-429 (2011).
    • (2011) Ann. Rev. Med. , vol.62 , pp. 411-429
    • Krueger, D.D.1    Bear, M.F.2
  • 94
    • 73849147822 scopus 로고    scopus 로고
    • Double-blind placebo-controlled trial of pentoxifylline added to risperidone: Effects on aberrant behavior in children with autism
    • Akhondzadeh S, Fallah J, Mohammadi MR, et al. Double-blind placebo-controlled trial of pentoxifylline added to risperidone: effects on aberrant behavior in children with autism. Prog. Neuropsychopharmacol. Biol. Psychiatry 34(1), 32-36 (2010).
    • (2010) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.34 , Issue.1 , pp. 32-36
    • Akhondzadeh, S.1    Fallah, J.2    Mohammadi, M.R.3
  • 95
    • 77956326352 scopus 로고    scopus 로고
    • Autism Speaks First industry-sponsored trial for the Autism Clinical Trials Network (ACTN) (Accessed 4 February 2013)
    • Autism Speaks. Autism Speaks announces results reported for the study of fluoxetine in autism (SOFIA). First industry-sponsored trial for the Autism Clinical Trials Network (ACTN) (2009). www.autismspeaks.org/about-us/press- releases/autism-speaks-announces-results-reported-study-fluoxetine-autism-sofia (Accessed 4 February 2013)
    • (2009) Autism Speaks Announces Results Reported for the Study of Fluoxetine in Autism (SOFIA)
  • 96
    • 84876143124 scopus 로고    scopus 로고
    • ClinicalTrials.gov (Accessed 2 March 2013)
    • ClinicalTrials.gov. A trial of memantine versus placebo in children with autism (2013). www.clinicaltrials.gov/ct2/show/NCT01372 449?term= A+trial+of+memantine+versus+pla cebo+in+children+with+autism.&rank=1 (Accessed 2 March 2013)
    • (2013) A Trial of Memantine Versus Placebo in Children with Autism


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.