Synthesis and biological evaluation of prodrugs of 2-fluoro-2-deoxyribose- 1-phosphate and 2,2-difluoro-2-deoxyribose-1-phosphate

Bioorganic and Medicinal Chemistry Letters

Volumn 23, Issue 9, 2013, Pages 2555-2559

  Hamon, Nadege ^a   Quintiliani, Maurizio ^a   Balzarini, Jan ^b   McGuigan, Christopher ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Deoxyribose; Fluorination; Phosphorylation; Prodrugs; Sugars

Indexed keywords

2 DEOXYRIBOSE; 2 FLUORO 2 DEOXYRIBOSE 1 PHOSPHATE; 2,2 DIFLUORO 2 DEOXYRIBOSE 1 PHOSPHATE; ANTIVIRUS AGENT; CYTOTOXIC AGENT; FLUORINE; PRODRUG; UNCLASSIFIED DRUG;

ARTICLE; DRUG SCREENING; DRUG STABILITY; FLUORINATION; HUMAN; HUMAN CELL; PHOSPHORYLATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL PROLIFERATION; DEOXYRIBONUCLEOTIDES; HIV-1; HIV-2; HUMANS; MICE; PRODRUGS; RIBOSEMONOPHOSPHATES; SIMPLEXVIRUS; VACCINIA VIRUS; VESICULOVIRUS;

EID: 84876105783     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2013.02.117     Document Type: Article

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