Synthesis and anticancer evaluation of 4'-C-methyl-2'-fluoro arabino nucleosides

Nucleosides, Nucleotides and Nucleic Acids

Volumn 28, Issue 5-7, 2009, Pages 657-677

  Tiwari, Kamal N ^a   Shortnacy Fowler, Anita T ^a   Parker, William B ^a   Waud, William R ^a   Secrist III, John A ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

2' fluoroarabino purine and pyrimidine; 4' c methylnucleosides; Anticancer activity; Nucleosides

Indexed keywords

1 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)CYTOSINE; 1 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)THYMINE; 1 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)URACIL; 2 CHLORO 6 METHOXY 9 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)PURINE; 2 CHLORO 9 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)ADENINE; 2,6 DIAMINO 9 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)PURINE; 2,6 DIAMINO 9 (3, 5 DI O BENZOYL 2 DEOXY 2 FLUORO 4 C METHYL BETA DARABINOFURANOSYL)PURINE; 2,6 DIAZIDO 9 (3, 5 DI O BENZOYL 2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)PURINE; 2,6 DICHLORO 9 (3,5 DI O BENZOYL 2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)PURINE; 6 CHLORO 9 (3,5 DI O BENZOYL 2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)PURINE; 9 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)ADENINE; 9 (2 DEOXY 2 FLUORO 4 C METHYL BETA DEXTRO ARABINOFURANOSYL)GUANINE; ANTINEOPLASTIC AGENT; NUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER SURVIVAL; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IC 50; KIDNEY CANCER; KIDNEY TUMOR; LEUKEMIA CELL; LUNG NON SMALL CELL CANCER; MALE; MELANOMA; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; PROSTATE CANCER; TUMOR VOLUME; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; ARABINONUCLEOSIDES; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; HALOGENATION; HUMANS; MICE; NEOPLASMS; PYRIMIDINE NUCLEOSIDES; PYRIMIDINE NUCLEOTIDES;

MUS;

EID: 75749153622     PISSN: 15257770     EISSN: 15322335     Source Type: Journal    
DOI: 10.1080/15257770903091946     Document Type: Article

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