메뉴 건너뛰기




Volumn 80, Issue 2, 2013, Pages 131-139

Continuous infusion of dexmedetomidine improves renal ischemia-reperfusion injury in rat kidney

Author keywords

Dexmedetomidine; Ischemia reperfusion injury; Kidney

Indexed keywords

CREATININE; DEXMEDETOMIDINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; MESSENGER RNA; NEURONAL NITRIC OXIDE SYNTHASE; PENTOBARBITAL; TUMOR NECROSIS FACTOR ALPHA;

EID: 84876092700     PISSN: 13454676     EISSN: 13473409     Source Type: Journal    
DOI: 10.1272/jnms.80.131     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 0037302813 scopus 로고    scopus 로고
    • The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats
    • Engelhard K, Werner C, Eberspächer E, et al.: The effect of the alpha 2-agonist dexmedetomidine and the N-methyl-D-aspartate antagonist S(+)-ketamine on the expression of apoptosis-regulating proteins after incomplete cerebral ischemia and reperfusion in rats. Anesth Analg 2003; 96: 524-531.
    • (2003) Anesth Analg , vol.96 , pp. 524-531
    • Engelhard, K.1    Werner, C.2    Eberspächer, E.3
  • 2
    • 34547455307 scopus 로고    scopus 로고
    • The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat hearts
    • Okada H, Kurita T, Mochizuki T, Morita K, Sato S.: The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat hearts. Resuscitation 2007; 74: 538-545.
    • (2007) Resuscitation , vol.74 , pp. 538-545
    • Okada, H.1    Kurita, T.2    Mochizuki, T.3    Morita, K.4    Sato, S.5
  • 3
    • 77649098609 scopus 로고    scopus 로고
    • Effect of dexmedetomidine on testicular torsion/detorsion damage in rats
    • Hanci V, Erol B, Bektaş S, et al.: Effect of dexmedetomidine on testicular torsion/detorsion damage in rats. Urol Int 2010; 84: 105-111.
    • (2010) Urol Int , vol.84 , pp. 105-111
    • Hanci, V.1    Erol, B.2    Bektaş, S.3
  • 4
    • 67349257928 scopus 로고    scopus 로고
    • Effects of dexmedetomidine on regulating endotoxin-induced up-regulation of inflammatory molecules in murine macrophages
    • Lai YC, Tsai PS, Huang CJ.: Effects of dexmedetomidine on regulating endotoxin-induced up-regulation of inflammatory molecules in murine macrophages. J Surg Res 2009; 154: 212-219.
    • (2009) J Surg Res , vol.154 , pp. 212-219
    • Lai, Y.C.1    Tsai, P.S.2    Huang, C.J.3
  • 5
    • 80054016568 scopus 로고    scopus 로고
    • Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice
    • Gu J, Chen J, Xia P, Tao G, Zhao H, Ma D.: Dexmedetomidine attenuates remote lung injury induced by renal ischemia-reperfusion in mice. Acta Anaesthesiol Scand 2011; 55: 1272-1278.
    • (2011) Acta Anaesthesiol Scand , vol.55 , pp. 1272-1278
    • Gu, J.1    Chen, J.2    Xia, P.3    Tao, G.4    Zhao, H.5    Ma, D.6
  • 7
    • 77954471082 scopus 로고    scopus 로고
    • Perioperative acute kidney injury: Risk factors, recognition, management, and outcomes
    • Borthwick E, Ferguson A.: Perioperative acute kidney injury: risk factors, recognition, management, and outcomes. BMJ 2010; 341: c3365.
    • (2010) BMJ , vol.341 c3365
    • Borthwick, E.1    Ferguson, A.2
  • 8
    • 0027156739 scopus 로고
    • Mechanisms of ischemic acute renal failure
    • Bonventre JV.: Mechanisms of ischemic acute renal failure. Kidney Int 1993; 43: 1160-1178.
    • (1993) Kidney Int , vol.43 , pp. 1160-1178
    • Bonventre, J.V.1
  • 9
    • 77953890977 scopus 로고    scopus 로고
    • Macrophages, dendritic cells, and kidney ischemia-reperfusion injury
    • Li L, Okusa MD.: Macrophages, dendritic cells, and kidney ischemia-reperfusion injury. Semin Nephrol 2010; 30: 268-277.
    • (2010) Semin Nephrol , vol.30 , pp. 268-277
    • Li, L.1    Okusa, M.D.2
  • 11
    • 84867032429 scopus 로고    scopus 로고
    • Acute kidney injury: A conspiracy of toll-like receptor 4 on endothelia, leukocytes, and tubules
    • Lu CY, Winterberg PD, Chen J, Hartono JR: Acute kidney injury: a conspiracy of toll-like receptor 4 on endothelia, leukocytes, and tubules. Pediatr Nephrol 2011; 10: 1847-1854.
    • (2011) Pediatr Nephrol , vol.10 , pp. 1847-1854
    • Lu, C.Y.1    Winterberg, P.D.2    Chen, J.3    Hartono, J.R.4
  • 12
    • 61649103976 scopus 로고    scopus 로고
    • Effect of dexmedetomidine on ischemia-reperfusion injury in rat kidney: A histopathologic study
    • Kocoglu H, Ozturk H, Ozturk H, Yilmaz F, Gulcu N.: Effect of dexmedetomidine on ischemia-reperfusion injury in rat kidney: a histopathologic study. Ren Fail 2009; 31: 70-74.
    • (2009) Ren Fail , vol.31 , pp. 70-74
    • Kocoglu, H.1    Ozturk, H.2    Ozturk, H.3    Yilmaz, F.4    Gulcu, N.5
  • 13
    • 79959410406 scopus 로고    scopus 로고
    • Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice
    • Gu J, Sun P, Zhao HR, et al.: Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice. Crit Care 2011; 15: R153.
    • (2011) Crit Care , vol.15 R153
    • Gu, J.1    Sun, P.2    Zhao, H.R.3
  • 14
    • 38049059187 scopus 로고    scopus 로고
    • Propofol attenuates ischaemia-reperfusion injury in the rat heart in vivo
    • Kobayashi I, Kokita N, Namiki A.: Propofol attenuates ischaemia-reperfusion injury in the rat heart in vivo. Eur J Anaesthesiol 2008; 25: 144-151.
    • (2008) Eur J Anaesthesiol , vol.25 , pp. 144-151
    • Kobayashi, I.1    Kokita, N.2    Namiki, A.3
  • 15
    • 0029926911 scopus 로고    scopus 로고
    • Auto- and crossspectral analysis of cardiovascular flucruarions during pentobarbital anesthesia in the rat
    • Yang CC, Kuo TB, Chan SH.: Auto- and crossspectral analysis of cardiovascular flucruarions during pentobarbital anesthesia in the rat. Arn J Physiol 1996; 270: H575-582.
    • (1996) Arn J Physiol , vol.270
    • Yang, C.C.1    Kuo, T.B.2    Chan, S.H.3
  • 16
    • 34247100304 scopus 로고    scopus 로고
    • Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis
    • Lee HT, Emala CW, Joo JD, Kim M.: Isoflurane improves survival and protects against renal and hepatic injury in murine septic peritonitis. Shock 2007; 27: 373-379.
    • (2007) Shock , vol.27 , pp. 373-379
    • Lee, H.T.1    Emala, C.W.2    Joo, J.D.3    Kim, M.4
  • 17
    • 0031473311 scopus 로고    scopus 로고
    • Pharmacokinetic-Pharmacodynamic Characterization of the Cardiovascular, Hypnotic, EEG and Ventilatory Responses to Dexmedetomidine in the Rat
    • Bol CJJG, Danhof M, Stanski DR, Mandema JW.: Pharmacokinetic-Pharmacodynamic Characterization of the Cardiovascular, Hypnotic, EEG and Ventilatory Responses to Dexmedetomidine in the Rat. J Pharmacol Exp Ther 1997; 283: 1051-1058.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1051-1058
    • Bol, C.J.J.G.1    Danhof, M.2    Stanski, D.R.3    Mandema, J.W.4
  • 18
    • 0032842402 scopus 로고    scopus 로고
    • Anesthetic Profile of Dexmedetomidine Identified by Stimulus-Response and Continuous Measurements in Rats
    • Bol CJJG, Vogelaar JP, Mandema JW.: Anesthetic Profile of Dexmedetomidine Identified by Stimulus-Response and Continuous Measurements in Rats. J Pharmacol Exp Ther 1999; 291: 153-160.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 153-160
    • Bol, C.J.J.G.1    Vogelaar, J.P.2    Mandema, J.W.3
  • 19
    • 49549108506 scopus 로고    scopus 로고
    • Evaluation of analgesic and sedative effects of continuous infusion of dexmedetomidine by measuring somatosensoryand auditory-evoked potentials in the rat
    • Franken ND, van Oostrom H, Stienen PJ, Doornenbal A, Hellebrekers LJ.: Evaluation of analgesic and sedative effects of continuous infusion of dexmedetomidine by measuring somatosensoryand auditory-evoked potentials in the rat. Vet Anaesth Analg 2008; 35: 424-431.
    • (2008) Vet Anaesth Analg , vol.35 , pp. 424-431
    • Franken, N.D.1    van Oostrom, H.2    Stienen, P.J.3    Doornenbal, A.4    Hellebrekers, L.J.5
  • 20
    • 0034045034 scopus 로고    scopus 로고
    • Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo
    • Chatterjee PK, Zacharowski K, Cuzzocrea S, Otto M, Thiemermann C.: Inhibitors of poly (ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo. FASEB J 2000; 14: 641-651.
    • (2000) FASEB J , vol.14 , pp. 641-651
    • Chatterjee, P.K.1    Zacharowski, K.2    Cuzzocrea, S.3    Otto, M.4    Thiemermann, C.5
  • 22
    • 33646201785 scopus 로고    scopus 로고
    • Macrophages contribute to the initiation of ischaemic acute renal failure in rats
    • Jo SK, Sung SA, Cho WY, Go KJ, Kim HK.: Macrophages contribute to the initiation of ischaemic acute renal failure in rats. Nephrol Dial Transplant 2006; 21: 1231-1239.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1231-1239
    • Jo, S.K.1    Sung, S.A.2    Cho, W.Y.3    Go, K.J.4    Kim, H.K.5
  • 23
    • 0035129634 scopus 로고    scopus 로고
    • Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia
    • Donnahoo KK, Meng X, Ao L, et al.: Differential cellular immunolocalization of renal tumour necrosis factor-alpha production during ischaemia versus endotoxaemia. Immunology 2001; 102: 53-58.
    • (2001) Immunology , vol.102 , pp. 53-58
    • Donnahoo, K.K.1    Meng, X.2    Ao, L.3
  • 24
    • 0027304756 scopus 로고
    • Expression of interleukin 6 and major histocompatibility complex molecules in tubular epithelial cells of diseased human kidneys
    • Fukatsu A, Matsuo S, Yuzawa Y, Miyai H, Futenma A, Kato K.: Expression of interleukin 6 and major histocompatibility complex molecules in tubular epithelial cells of diseased human kidneys. Lab Investig 1993; 69: 58-67.
    • (1993) Lab Investig , vol.69 , pp. 58-67
    • Fukatsu, A.1    Matsuo, S.2    Yuzawa, Y.3    Miyai, H.4    Futenma, A.5    Kato, K.6
  • 25
    • 33644874979 scopus 로고    scopus 로고
    • Maladaptive role of IL-6 in ischemic acute renal failure
    • Kielar ML, John R, Bennett M, et al.: Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol 2005; 16: 3315-3325.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3315-3325
    • Kielar, M.L.1    John, R.2    Bennett, M.3
  • 26
    • 84862991350 scopus 로고    scopus 로고
    • Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4
    • Chen J, Hartono JR, John R, et al.: Early interleukin 6 production by leukocytes during ischemic acute kidney injury is regulated by TLR4. Kidney Int 2011; 80: 504-515.
    • (2011) Kidney Int , vol.80 , pp. 504-515
    • Chen, J.1    Hartono, J.R.2    John, R.3
  • 27
    • 14344261020 scopus 로고    scopus 로고
    • Thiemermann C. Endogenous Interleukin-6 Enhances the Renal Injury, Dysfunction, and Inflammation Caused by Ischemia/Reperfusion
    • Patel NS, Chatterjee PK, Di Paola R, et al.: Thiemermann C. Endogenous Interleukin-6 Enhances the Renal Injury, Dysfunction, and Inflammation Caused by Ischemia/Reperfusion. J Pharmacol Exp Ther 2005; 312: 1170-1178.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1170-1178
    • Patel, N.S.1    Chatterjee, P.K.2    Di Paola, R.3
  • 28
    • 0033736388 scopus 로고    scopus 로고
    • Ischemiareperfusion injury in renal transplantation is independent of the immunologic background
    • Dragun D, Hoff U, Park JK, et al.: Ischemiareperfusion injury in renal transplantation is independent of the immunologic background. Kidney Int 2000; 58: 2166-2177.
    • (2000) Kidney Int , vol.58 , pp. 2166-2177
    • Dragun, D.1    Hoff, U.2    Park, J.K.3
  • 29
    • 0028332056 scopus 로고
    • Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions
    • Forstermann U, Closs EI, Pollock JS.: Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. Hypertension 1994; 23: 1121-1131.
    • (1994) Hypertension , vol.23 , pp. 1121-1131
    • Forstermann, U.1    Closs, E.I.2    Pollock, J.S.3
  • 30
    • 33745699168 scopus 로고    scopus 로고
    • Nitric oxide in the kidney: Functions and regulation of synthesis
    • Mount PF, Power DA.: Nitric oxide in the kidney: functions and regulation of synthesis. Acta Physiol 2006; 187: 433-446.
    • (2006) Acta Physiol , vol.187 , pp. 433-446
    • Mount, P.F.1    Power, D.A.2
  • 31
    • 58849099597 scopus 로고    scopus 로고
    • Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion
    • Kwon O, Hong SM, Ramesh G.: Diminished NO generation by injured endothelium and loss of macula densa nNOS may contribute to sustained acute kidney injury after ischemia-reperfusion. Am J Physiol Renal Physiol 2009; 296: F25-33.
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Kwon, O.1    Hong, S.M.2    Ramesh, G.3
  • 32
    • 0033984221 scopus 로고    scopus 로고
    • Nitric Oxide Synthase Activity and Isoforms in Rat Renal Vasculature
    • Mattson DL, Wu F.: Nitric Oxide Synthase Activity and Isoforms in Rat Renal Vasculature. Hypertension 2000; 35: 337-341.
    • (2000) Hypertension , vol.35 , pp. 337-341
    • Mattson, D.L.1    Wu, F.2
  • 33
    • 0036380998 scopus 로고    scopus 로고
    • Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury
    • Chatterjee PK, Zacharowski K, Cuzzocrea S, et al.: Lipoteichoic acid from Staphylococcus aureus reduces renal ischemia/reperfusion injury. Kidney Int 2002; 62: 1249-1263.
    • (2002) Kidney Int , vol.62 , pp. 1249-1263
    • Chatterjee, P.K.1    Zacharowski, K.2    Cuzzocrea, S.3
  • 34
    • 57349105852 scopus 로고    scopus 로고
    • Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers
    • Snapir A, Talke P, Posti J, Huiku M, Kentala E, Scheinin M.: Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers. Br J Anaesth 2009; 102: 38-46.
    • (2009) Br J Anaesth , vol.102 , pp. 38-46
    • Snapir, A.1    Talke, P.2    Posti, J.3    Huiku, M.4    Kentala, E.5    Scheinin, M.6
  • 35
    • 0027217287 scopus 로고
    • Computer-controlled infusion of intravenous dexmedetomidine hydrochloride in adult human volunteers
    • Dyck JB, Maze M, Haack C, Azarnoff DL, Vuorilehto L, Shafer SL.: Computer-controlled infusion of intravenous dexmedetomidine hydrochloride in adult human volunteers. Anesthesiology 1993; 78: 821-828.
    • (1993) Anesthesiology , vol.78 , pp. 821-828
    • Dyck, J.B.1    Maze, M.2    Haack, C.3    Azarnoff, D.L.4    Vuorilehto, L.5    Shafer, S.L.6
  • 36
    • 0030862290 scopus 로고    scopus 로고
    • Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine
    • Talke P, Richardson CA, Scheinin M, Fisher DM.: Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg 1997; 85: 1136-1142.
    • (1997) Anesth Analg , vol.85 , pp. 1136-1142
    • Talke, P.1    Richardson, C.A.2    Scheinin, M.3    Fisher, D.M.4
  • 37
    • 0032905215 scopus 로고    scopus 로고
    • Alpha-2 and imidazoline receptor agonists. Their pharmacology and the rapeutic role
    • Khan ZP, Ferguson CN, Jones RM.: alpha-2 and imidazoline receptor agonists. Their pharmacology and the rapeutic role. Anaesthesia 1999; 54: 146-165.
    • (1999) Anaesthesia , vol.54 , pp. 146-165
    • Khan, Z.P.1    Ferguson, C.N.2    Jones, R.M.3
  • 38
    • 59149086184 scopus 로고    scopus 로고
    • Effects of Dexmedetomidine on Regulating Pulmonary Inflammation in a Rat Model of Ventilator-induced Lung Injury
    • Yang CL, Tsai PS, Huang CJ.: Effects of Dexmedetomidine on Regulating Pulmonary Inflammation in a Rat Model of Ventilator-induced Lung Injury. Acta Anaesthesiol Taiwan 2008; 46: 151-159.
    • (2008) Acta Anaesthesiol Taiwan , vol.46 , pp. 151-159
    • Yang, C.L.1    Tsai, P.S.2    Huang, C.J.3
  • 39
    • 77953014696 scopus 로고    scopus 로고
    • Protective effects of propofol against ischemia/ reperfusion injury in rat kidneys
    • Yuzbasioglu MF, Aykas A, Kurutas EB, Sahinkanat T.: Protective effects of propofol against ischemia/ reperfusion injury in rat kidneys. Ren Fail 2010; 32: 578-583.
    • (2010) Ren Fail , vol.32 , pp. 578-583
    • Yuzbasioglu, M.F.1    Aykas, A.2    Kurutas, E.B.3    Sahinkanat, T.4
  • 40
    • 9444221391 scopus 로고    scopus 로고
    • Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo
    • Lee HT, Ota-Setlik A, Fu Y, Nasr SH, Emala CW.: Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo. Anesthesiology 2004; 101: 1313-1324.
    • (2004) Anesthesiology , vol.101 , pp. 1313-1324
    • Lee, H.T.1    Ota-Setlik, A.2    Fu, Y.3    Nasr, S.H.4    Emala, C.W.5
  • 43
    • 34247155806 scopus 로고    scopus 로고
    • Involvement of central alpha 1- and alpha 2-adrenoceptors on cardiovascular responses to moxonidine
    • Moreira TS, Takakura AC, Menani JV, Colombari E.: Involvement of central alpha 1- and alpha 2-adrenoceptors on cardiovascular responses to moxonidine. Eur J Pharmacol 2007; 563: 164-171.
    • (2007) Eur J Pharmacol , vol.563 , pp. 164-171
    • Moreira, T.S.1    Takakura, A.C.2    Menani, J.V.3    Colombari, E.4
  • 44
    • 3242803483 scopus 로고    scopus 로고
    • Central blockade of nitric oxide synthesis reduces moxonidine-induced hypotension
    • Moreira TS, Takakura AC, Menani JV, Sato MA, Colombari E.: Central blockade of nitric oxide synthesis reduces moxonidine-induced hypotension. Br J Pharmacol 2004; 142: 765-771.
    • (2004) Br J Pharmacol , vol.142 , pp. 765-771
    • Moreira, T.S.1    Takakura, A.C.2    Menani, J.V.3    Sato, M.A.4    Colombari, E.5
  • 45
    • 2942565800 scopus 로고    scopus 로고
    • Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats
    • Taniguchi T, Kidani Y, Kanakura H, Takemoto Y, Yamamoto K.: Effects of dexmedetomidine on mortality rate and inflammatory responses to endotoxin-induced shock in rats. Crit Care Med 2004; 32: 1322-1326.
    • (2004) Crit Care Med , vol.32 , pp. 1322-1326
    • Taniguchi, T.1    Kidani, Y.2    Kanakura, H.3    Takemoto, Y.4    Yamamoto, K.5
  • 46
    • 0026519531 scopus 로고
    • Subtypes of alpha 1- and alpha 2- adrenergic receptors
    • Bylund DB.: Subtypes of alpha 1- and alpha 2- adrenergic receptors. FASEB J 1992; 6: 832-839.
    • (1992) FASEB J , vol.6 , pp. 832-839
    • Bylund, D.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.