메뉴 건너뛰기




Volumn 35, Issue 5, 2008, Pages 424-431

Evaluation of analgesic and sedative effects of continuous infusion of dexmedetomidine by measuring somatosensory- and auditory-evoked potentials in the rat

Author keywords

AEP; Neurophysiology; Nociception; Pain; Sedation; SEP

Indexed keywords

ANIMALIA; RATTUS; RATTUS NORVEGICUS;

EID: 49549108506     PISSN: 14672987     EISSN: 14672995     Source Type: Journal    
DOI: 10.1111/j.1467-2995.2008.00404.x     Document Type: Article
Times cited : (20)

References (27)
  • 1
    • 0034106127 scopus 로고    scopus 로고
    • Dexmedetomidine
    • discussion 269-270.
    • Bhana N, Goa KL, McClellan KJ (2000) Dexmedetomidine. Drugs 59, 263 268 discussion 269-270.
    • (2000) Drugs , vol.59 , pp. 263-268
    • Bhana, N.1    Goa, K.L.2    McClellan, K.J.3
  • 2
    • 0032842402 scopus 로고    scopus 로고
    • Anesthetic Profile of dexmedetomidine identified by stimulus-respons and continuous measurements in rats
    • Bol CJJG, Vogelaar JPW, Mandema JW (1999) Anesthetic Profile of dexmedetomidine identified by stimulus-respons and continuous measurements in rats. J Pharm Exp Ther 291, 153 160.
    • (1999) J Pharm Exp Ther , vol.291 , pp. 153-160
    • Cjjg, B.1    Vogelaar, J.P.W.2    Mandema, J.W.3
  • 3
    • 0024393339 scopus 로고
    • Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine
    • Doze V, Chen BX, Li Z et al. (1989) Pharmacologic characterization of the receptor mediating the hypnotic action of dexmedetomidine. Acta Vet Scand Suppl 85, 61 64.
    • (1989) Acta Vet Scand Suppl , vol.85 , pp. 61-64
    • Doze, V.1    Chen, B.X.2    Li, Z.3
  • 4
    • 0033860761 scopus 로고    scopus 로고
    • The effects of increasing plasma concentrations of dexmedetomidine in humans
    • Ebert TJ, Hall JE, Barney JA et al. (2000) The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 93, 382 394.
    • (2000) Anesthesiology , vol.93 , pp. 382-394
    • Ebert, T.J.1    Hall, J.E.2    Barney, J.A.3
  • 5
    • 33745399101 scopus 로고    scopus 로고
    • Evaluation of the clinical efficacy and safety of dexmedetomidine or medetomidine in cats and their reversal with atipamezole
    • Granholm M, McKusick BC, Westerholm FC et al. (2006) Evaluation of the clinical efficacy and safety of dexmedetomidine or medetomidine in cats and their reversal with atipamezole. Vet Anaesth Analg 33, 214 223.
    • (2006) Vet Anaesth Analg , vol.33 , pp. 214-223
    • Granholm, M.1    McKusick, B.C.2    Westerholm, F.C.3
  • 6
    • 0034637238 scopus 로고    scopus 로고
    • The rat vertex-middle latency auditory-evoked potential as indicator of anaesthetic depth: A comparison with evoked-reflex testing
    • Haberham ZL, van den Brom WE, Venker-Van Haagen AJ et al. (2000) The rat vertex-middle latency auditory-evoked potential as indicator of anaesthetic depth: a comparison with evoked-reflex testing. Brain Res 873, 287 290.
    • (2000) Brain Res , vol.873 , pp. 287-290
    • Haberham, Z.L.1    Van Den Brom, W.E.2    Venker-Van Haagen, A.J.3
  • 7
    • 0034049613 scopus 로고    scopus 로고
    • Sedative, amnestic, and analgesic properties of small-dose dexmedetomdine infusions
    • Hall JE, Uhrich TD, Barney JA et al. (2000) Sedative, amnestic, and analgesic properties of small-dose dexmedetomdine infusions. Anesth Analg 90, 699 705.
    • (2000) Anesth Analg , vol.90 , pp. 699-705
    • Hall, J.E.1    Uhrich, T.D.2    Barney, J.A.3
  • 8
    • 0038721962 scopus 로고    scopus 로고
    • Propofol surpresses the sleep state-dependent P13 midlatency auditory evoked potential in the rat
    • Homma Y, Teneud L, Skinner RD et al. (2003) Propofol surpresses the sleep state-dependent P13 midlatency auditory evoked potential in the rat. Brain Res Bull 61, 189 196.
    • (2003) Brain Res Bull , vol.61 , pp. 189-196
    • Homma, Y.1    Teneud, L.2    Skinner, R.D.3
  • 9
    • 0030609171 scopus 로고    scopus 로고
    • Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice
    • Hunter JC, Fontana DJ, Hedley LR et al. (1997) Assessment of the role of alpha2-adrenoceptor subtypes in the antinociceptive, sedative and hypothermic action of dexmedetomidine in transgenic mice. Br J Pharmacol 122, 1339 1344.
    • (1997) Br J Pharmacol , vol.122 , pp. 1339-1344
    • Hunter, J.C.1    Fontana, D.J.2    Hedley, L.R.3
  • 10
    • 0345435954 scopus 로고    scopus 로고
    • On-line analysis of middle latency auditory evoked potentials (MLAEP) for monitoring depth of anaesthesia in laboratory rats
    • Jensen EW, Nygaard M, Henneberg SW (1998) On-line analysis of middle latency auditory evoked potentials (MLAEP) for monitoring depth of anaesthesia in laboratory rats. Med Eng Phys 20, 722 728.
    • (1998) Med Eng Phys , vol.20 , pp. 722-728
    • Jensen, E.W.1    Nygaard, M.2    Henneberg, S.W.3
  • 11
    • 0030662399 scopus 로고    scopus 로고
    • Auditory evoked potential index: A quantitative measure of changes in auditory evoked potentials during general anaesthesia
    • Mantzaridis H, Kenny GN (1997) Auditory evoked potential index: a quantitative measure of changes in auditory evoked potentials during general anaesthesia. Anaesthesia 52, 1030 1036.
    • (1997) Anaesthesia , vol.52 , pp. 1030-1036
    • Mantzaridis, H.1    Kenny, G.N.2
  • 12
    • 0028938012 scopus 로고
    • A middle latency auditory-evoked potential in the rat
    • Miyazato H, Skinner RD, Reese NB et al. (1995) A middle latency auditory-evoked potential in the rat. Brain Res 37, 247 255.
    • (1995) Brain Res , vol.37 , pp. 247-255
    • Miyazato, H.1    Skinner, R.D.2    Reese, N.B.3
  • 13
    • 0033559769 scopus 로고    scopus 로고
    • Midlatency auditory evoked potentials in the rat: Effects of interventions that modulate arousal
    • Miyazato H, Skinner RD, Cobb M et al. (1999) Midlatency auditory evoked potentials in the rat: effects of interventions that modulate arousal. Brain Res Bull 48, 545 553.
    • (1999) Brain Res Bull , vol.48 , pp. 545-553
    • Miyazato, H.1    Skinner, R.D.2    Cobb, M.3
  • 14
    • 0034456892 scopus 로고    scopus 로고
    • Locus coeruleus involvement in the effects of immobilization stress on the P13 midlatency auditory evoked potential in the rat
    • Miyazato H, Skinner RD, Garcia-Rill E (2000) Locus coeruleus involvement in the effects of immobilization stress on the P13 midlatency auditory evoked potential in the rat. Prog Neuro-Psychopharmacol & Biol Psychiat 24, 1177 1201.
    • (2000) Prog Neuro-Psychopharmacol & Biol Psychiat , vol.24 , pp. 1177-1201
    • Miyazato, H.1    Skinner, R.D.2    Garcia-Rill, E.3
  • 15
    • 32544446544 scopus 로고    scopus 로고
    • Rapid brain discrimination of sounds of objects
    • Murray MM, Camen C, Gonzalez Andino SL et al. (2006) Rapid brain discrimination of sounds of objects. J Neurosci 26, 1293 1302.
    • (2006) J Neurosci , vol.26 , pp. 1293-1302
    • Murray, M.M.1    Camen, C.2    Gonzalez Andino, S.L.3
  • 16
    • 0034710886 scopus 로고    scopus 로고
    • Mechanisms and streams for processing of "what" and "where" in auditory cortex
    • Rauschecker JP, Tian B (2000) Mechanisms and streams for processing of "what" and "where" in auditory cortex. Proc Natl Acad Sci U S A 97, 11800 11806.
    • (2000) Proc Natl Acad Sci U S a , vol.97 , pp. 11800-11806
    • Rauschecker, J.P.1    Tian, B.2
  • 17
    • 0025981022 scopus 로고
    • Central alpha 2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine
    • Savola JM, Virtanen R (1991) Central alpha 2-adrenoceptors are highly stereoselective for dexmedetomidine, the dextro enantiomer of medetomidine. Eur J Pharmacol 195, 193 199.
    • (1991) Eur J Pharmacol , vol.195 , pp. 193-199
    • Savola, J.M.1    Virtanen, R.2
  • 18
    • 0028178222 scopus 로고
    • Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain
    • Scheinin M, Lomasney JW, Hayden-Hixson DM et al. (1994) Distribution of alpha 2-adrenergic receptor subtype gene expression in rat brain. Brain Res Mol Brain Res 21, 133 149.
    • (1994) Brain Res Mol Brain Res , vol.21 , pp. 133-149
    • Scheinin, M.1    Lomasney, J.W.2    Hayden-Hixson, D.M.3
  • 19
    • 0033870604 scopus 로고    scopus 로고
    • Alpha2-Adrenoceptor agonists in anaesthesia: A new paradigm
    • Scholz J, Tonner PH (2000) Alpha2-Adrenoceptor agonists in anaesthesia: a new paradigm. Curr Opin Anaesthesiol 13, 437 442.
    • (2000) Curr Opin Anaesthesiol , vol.13 , pp. 437-442
    • Scholz, J.1    Tonner, P.H.2
  • 20
    • 0027416955 scopus 로고
    • Multiple brain systems generating the rat auditory evoked potential. I. Characterization of the auditory cortex response
    • Simpson GV, Knight RT (1993a) Multiple brain systems generating the rat auditory evoked potential. I. Characterization of the auditory cortex response. Brain Res 602, 240 250.
    • (1993) Brain Res , vol.602 , pp. 240-250
    • Simpson, G.V.1    Knight, R.T.2
  • 21
    • 0027522461 scopus 로고
    • Multiple brain systems generating the rat auditory evoked potential. II. Dissociation of auditory cortex and non-lemniscal generator systems
    • Simpson GV, Knight RT (1993b) Multiple brain systems generating the rat auditory evoked potential. II. Dissociation of auditory cortex and non-lemniscal generator systems. Brain Res 602, 251 263.
    • (1993) Brain Res , vol.602 , pp. 251-263
    • Simpson, G.V.1    Knight, R.T.2
  • 22
    • 0037841527 scopus 로고    scopus 로고
    • Evaluation of methods for eliciting somatosensory evoked potentials in the awake, freely moving rat
    • Stienen PJ, Haberham ZL, van den Brom WE et al. (2003) Evaluation of methods for eliciting somatosensory evoked potentials in the awake, freely moving rat. J Neurosci Methods 126, 79 90.
    • (2003) J Neurosci Methods , vol.126 , pp. 79-90
    • Stienen, P.J.1    Haberham, Z.L.2    Van Den Brom, W.E.3
  • 23
    • 9644302412 scopus 로고    scopus 로고
    • Differences between primary somatosensory cortex- and vertex-derived somatosensory-evoked potentials in the rat
    • Stienen PJ, van den Brom WE, de Groot HNM et al. (2004) Differences between primary somatosensory cortex- and vertex-derived somatosensory-evoked potentials in the rat. Brain Res 1030, 256 266.
    • (2004) Brain Res , vol.1030 , pp. 256-266
    • Stienen, P.J.1    Van Den Brom, W.E.2    De Groot, H.N.M.3
  • 24
    • 25144448256 scopus 로고    scopus 로고
    • Differences between somatosensory-evoked potentials recorded from the ventral posterolateral thalamic nucleus, primary somatosensory cortex and vertex in the rat
    • Stienen PJ, van den Brom WE, de Groot HNM et al. (2005) Differences between somatosensory-evoked potentials recorded from the ventral posterolateral thalamic nucleus, primary somatosensory cortex and vertex in the rat. Brain Res Bull 67, 269 280.
    • (2005) Brain Res Bull , vol.67 , pp. 269-280
    • Stienen, P.J.1    Van Den Brom, W.E.2    De Groot, H.N.M.3
  • 25
    • 33746210124 scopus 로고    scopus 로고
    • Vertex-recorded, rather than primary somatosensory cortex-recorded, somatosensory-evoked potentials signal unpleasantness of noxious stimuli in the rat
    • Stienen PJ, van Oostrom H, van den Bos R et al. (2006) Vertex-recorded, rather than primary somatosensory cortex-recorded, somatosensory-evoked potentials signal unpleasantness of noxious stimuli in the rat. Brain Res Bull 70, 203 212.
    • (2006) Brain Res Bull , vol.70 , pp. 203-212
    • Stienen, P.J.1    Van Oostrom, H.2    Van Den Bos, R.3
  • 26
    • 33846021957 scopus 로고    scopus 로고
    • Somatosensory-evoked potentials indicate increased unpleasantness of noxious stimuli in response to increasing stimulus intensities in the rat
    • van Oostrom H, Stienen PJ, van den Bos R et al. (2007) Somatosensory-evoked potentials indicate increased unpleasantness of noxious stimuli in response to increasing stimulus intensities in the rat. Brain Res Bull 71, 404 409.
    • (2007) Brain Res Bull , vol.71 , pp. 404-409
    • Van Oostrom, H.1    Stienen, P.J.2    Van Den Bos, R.3
  • 27
    • 0030908440 scopus 로고    scopus 로고
    • Neuroanatomy of the pain system and of the pathways that modulate pain
    • Willis WD, Westlund KN (1997) Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neurophysiol 14, 2 31.
    • (1997) J Clin Neurophysiol , vol.14 , pp. 2-31
    • Willis, W.D.1    Westlund, K.N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.