Lack of cross-protection against invasive pneumonia caused by heterologous strains following murine Streptococcus pneumoniae nasopharyngeal colonisation despite whole cell ELISAs showing significant cross-reactive IgG

Vaccine

Volumn 31, Issue 19, 2013, Pages 2328-2332

  Cohen, Jonathan M ^a,b   Wilson, Robert ^a   Shah, Pranali ^a   Baxendale, Helen E ^b,c   Brown, Jeremy S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c PAPWORTH HOSPITAL   (United Kingdom)

Author keywords

Antibody; Colonisation; Cross protection; Streptococcus pneumoniae

Indexed keywords

BACTERIAL ANTIGEN; CD1 ANTIGEN; IMMUNOGLOBULIN G ANTIBODY;

ANIMAL EXPERIMENT; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ANTIBODY TITER; ANTIGEN BINDING; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIUM CULTURE; CONTROLLED STUDY; CROSS PROTECTION; CROSS REACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; MOUSE; NASOPHARYNX; NONHUMAN; PRIORITY JOURNAL; SEROTYPE; STREPTOCOCCUS PNEUMONIA; WHOLE CELL;

ANIMALS; ANTIBODIES; ANTIBODIES, BACTERIAL; CROSS REACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; IMMUNOGLOBULIN G; MICE; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; PNEUMONIA; STREPTOCOCCUS PNEUMONIAE; VACCINATION; VACCINES;

EID: 84876085740     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.03.013     Document Type: Article

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