Infection with conditionally virulent Streptococcus pneumoniae Δpab strains induces antibody to conserved protein antigens but does not protect against systemic infection with heterologous strains

Infection and Immunity

Volumn 79, Issue 12, 2011, Pages 4965-4976

  Chimalapati, Suneeta ^a   Cohen, Jonathan ^a   Camberlein, Emilie ^a   Durmort, Claire ^b   Baxendale, Helen ^c   de Vogel, Corné ^d   van Belkum, Alex ^d   Brown, Jeremy S ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b CEA GRENOBLE   (France)

^c PAPWORTH HOSPITAL   (United Kingdom)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBENZOIC ACID; BACTERIAL ANTIGEN; BACTERIUM ANTIBODY; DRINKING WATER; IMMUNOGLOBULIN G; BACTERIAL PROTEIN; BACTERIAL VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BACTERIAL VIRULENCE; FEMALE; GENE DELETION; MOUSE; NASOPHARYNX; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; SEPSIS; SEROTYPE; STREPTOCOCCUS PNEUMONIAE; VACCINATION; ANIMAL; BIOSYNTHESIS; GENETICS; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PATHOGENICITY; TIME; VIRULENCE;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; FEMALE; MICE; PNEUMOCOCCAL INFECTIONS; STREPTOCOCCUS PNEUMONIAE; TIME FACTORS; VACCINATION; VIRULENCE;

EID: 84862908090     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.05923-11     Document Type: Article

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