Evaluation of antidiabetic phytochemicals in syzygium cumini (L.) skeels (Family: Myrtaceae)

Journal of Applied Pharmaceutical Science

Volumn 2, Issue 10, 2012, Pages 094-098

  Alam, Md Rashedul ^a   Rahman, Akib Bin ^b   Moniruzzaman, Md ^a   Kadir, Mohammad Fahim ^c   Haque, Md Ahsanul ^c   Alvi, Mohammad Razi Ul Hasan ^a   Ratan, Md ^a  

^a UNIVERSITY OF DHAKA   (Bangladesh)

^b JAHANGIRNAGAR UNIVERSITY   (Bangladesh)

^c UNIVERSITY OF ASIA PACIFIC   (Bangladesh)

Author keywords

NMR; Phytochemical constituents; Plant extracts; Syzygium cumini leaves

Indexed keywords

EID: 84876067995     PISSN: None     EISSN: 22313354     Source Type: Journal    
DOI: 10.7324/JAPS.2012.21019     Document Type: Article

References (33)

1. Aratanechemuge Y., Hibasami H., Sanpin K., Katsuzaki H., Imail K., Komiya T. Induction of apoptosis by lupeol isolated from mokumen (Gossampinus malabarica L. Merr) in human promyelotic leukemia HL-60 cells. J. Oncol, Rep. 2004; 11: 289-292.
2. Ayyanar M., Subash-Babu P. Syzygium cumini (L.) Skeels: A review of its phytochemical constituents and traditional uses. Asian Pacific Journal of Tropical Biomedicine. 2012;(2): 240-246.
3. Batta AK., Xuab G., Honda A., Miyazaki T., Salen G. Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat. Journal of Pharmaceutical Sciences. 2006; 55(3): 292-299.
4. Bhargava KK., Dayar R. Seshadri TR. Chemical components of Eugenia jambolona stem bark. Current Science. 1974; 43(20): 645-646.
5. Bhuyan MA., Mia MY. Rashid MA. Antibacterial principles of the seed of Eugenia jambolana. Bangladesh J. Botany. 1996; 25: 239-241.
6. Bopp A., Bona KS., Bellé LP., Moresco RN., Moretto MB. Syzygium cumini inhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients. Fundamental & Clinical Pharmacology. 2009; 23: 501-507.
7. Chase MW., Reveal JL. A phytogenetic classification of land plants to accompany APG III. Botanical Journal of Linnean Society. 2009; 161: 122-127.
8. Chaudhary B., Mukhopadhyay K. Syzygium cumini (L.) skeels: a potential source of nutraceuticals. Intrnational J. of Pharm. and Bio. Sci. 2012; 2(1): 46-53
9. Chaudhuei AKN., Pal S., Gomes A., Bhattacharya S. Antiinflammatory and related actions of Syzygium cumini seed extract. Phytotherphy Research. 1990; 4: 5-10.
10. Chiu HL., Wu JH., Tung YT., Lee TH., Chien SC., Kuo YH. Triterpenoids and Aromatics from Derris laxiflora. J. Nat. Prod. 2008; 71 (11): 1829-1832.
11. Farswana M., Mazumder P., Parcha V. Modulatory effect of an isolated compound from Syzygium cumini seeds on biochemical parameters of diabetes in rats. International Journal of Green Pharmacy. 2009; 3: 128-133.
12. Gowri SS. Vasantha K. Phytochemical Screening and Antibacterial Activity of Syzygium cumini (L.) (Myrtaceae) Leaves Extracts. International Journal of PharmTech Research. 2010; 2:1569- 1573.
13. Gupta R., Sharma AK., Dobhal MP., Sharma MC., Gupta RS. Antidiabetic and antioxidant potential of β-sitosterol in streptozotocin- induced experimental hyperglycemia. Journal of Diabetes. 2011; 3(1):29- 37.
14. Gupta R., Sharma AK., Sharma MC., Dobhal MP., Gupta RS. Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycaemia. Nat Prod Res. 2012; 26(12):1125-1129.
15. Indira G., Mohan RM. National Institute of Nutrition, Indian Council of Medical Research, Hyderabad, India. 1992; 34-37.
16. Jamaluddin F., Mohamed S., Lajis MN. Hypoglycaemic effect of Parkia speciosa seeds due to the synergistic action of β-sitosterol and stigmasterol. Food Chemistry 1994; 49(4): 339-345.
17. Kolak U., Topcu G., Birteksoz S., Otuk G., Ulubelen A. Terpenoids and steroids from the roots of Salvia blepharochlaena, Turk. J. Chem. 2005; 29: 177-186.
18. Krishnaswamy NR., Prasanna S., Seshandri TR., Vedantham TNC. α- and β-Amyrin esters and sitosterol glucoside from Spilanthes acmella. Phytochemistry. 1975; 14: 1666-1667.
19. Kumar A., Ilavarasan R., Jayachandran T., Deecaraman M., Aravindhan P., Padmanabhan N., Krishan MRV. Anti-diabetic activity of Syzygium cumini and its isolated compound against streptozotocin-induced diabetic rats. Journal of Medicinal Plants Research. 2008; 2: 246-249.
20. Kuncha J., Ayyachamy M., Mariappan M. In-vitro evaluation of nitric oxide scavenging activity of methanolic and aqueous extract of syzygium cumini Linn. Bark (Myrtaceae). Int. J Pharm Sci Res. 2012; 3(2): 615-619.
21. Leelavinothan P., Saravanan G. Effects of Syzygium Cumini bark on blood glucose, plasma insulin and C-peptide in streptozotocininduced diabetic rats. International Journal of Endocrinology and Metabolism 2006; 4: 96-105.
22. Li WL., Zheng HC., Bukuru J., De Kimpe N., Natural medicines used in the traditional Chines medical system for therapy of diabetes mellitus. J Ethnopharmacol. 2004; 92: 1-21.
23. Martinez SB. Del Valle MJ. Storage stability and sensory quality of duhat Syzygium cumini Linn. anthocyanins as food colorant. UP Home Economic Journal. 1981; 9(1).
24. Morales G., Sierra P., Mancilla A., Paredes A, Loyola LA., Gallardo O., Borquez J. Secondary metabolites from four medicinal plants from northern Chile antimicrobial activity and biotoxicity against Artemia salina, J Chile Chem. Soc. 2003; 48: 13-18.
25. Panda S., Jafri M., Kara A., Meheta BK. Thyroid inhibitory, antiperoxidative and hypoglycemic effects of stigmasterol isolated from Butea monosperma. Fitoterapia. 2009; 80 (2): 123-126.
26. Ravi K., Rajasekaran S., Subramanian S. Antihyperlipidemic effect of Eugenia jambolana seed kernel on streptozotocin-induced diabetes in rats. Food Chem. Toxicol. 2005; 43: 1433-1439.
27. Sagrawat H, Mann AS, Kharya MD. Pharmacological potential of Eugenia jambolana: A review. Pharmaco. Mag. 2006; 2: 96-105.
28. Saravanan G., Pari L. Hypoglycaemic and Antihyperglycaemic Effect of Syzygium cumini Bark in Streptozotocin-Induced Diabetic Rats. Journal of Pharmacology and Toxicology. 2008; 3: 1-10.
29. Sengupta P. Das PB. Terpenoids and related compounds IV, Triterpenoids in the stem bark of Syzygium cumini bark. Indin journal of Chemical Science. 1965; 42(4): 255-258.
30. Sharma P., Mehta PM. In Dravyaguna vignyan. (The Chowkhamba Vidyabhawan), Part II & III, Varansi. 1969; 586.
31. Wealth of India. Ed. 10, CSIR, New Delhi. 1982; 100-104.
32. Wealth of India. Raw materials, New Delhi: CSIR. 1976; 10: 100-104.
33. Williamsen EM. Major Herbs in Ayurveda. Churchill Livingstone. 2002; 279-282.