메뉴 건너뛰기




Volumn 13, Issue 5, 2013, Pages 643-656

Cancer stem cell antigen-based vaccines: The preferred strategy for active specific immunotherapy of metastatic melanoma?

Author keywords

Active specific immunotherapy; Cancer stem cells; Melanoma; Therapeutic cancer vaccines

Indexed keywords

2,4 DINITROPHENOL; ALPHA INTERFERON; BACTERIAL ANTIGEN; BCG VACCINE; CANCER VACCINE; CYCLOPHOSPHAMIDE; DACARBAZINE; GANGLIOSIDE; INTERLEUKIN 2; IPILIMUMAB; TEMOZOLOMIDE; VEMURAFENIB; VIRUS ANTIGEN;

EID: 84876029350     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2013.759556     Document Type: Review
Times cited : (20)

References (85)
  • 2
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong S-J, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009;27:6199-206
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.-J.3
  • 3
    • 84864040339 scopus 로고    scopus 로고
    • Should high-dose interleukin-2 still be the preferred treatment for patients with metastatic melanoma?
    • Dillman RO, Barth NM, VanderMolen LA, et al. Should high-dose interleukin-2 still be the preferred treatment for patients with metastatic melanoma? Cancer Biother Radiopharm 2012;27:337-43
    • (2012) Cancer Biother Radiopharm , vol.27 , pp. 337-343
    • Dillman, R.O.1    Barth, N.M.2    Vandermolen, L.A.3
  • 4
    • 79959795786 scopus 로고    scopus 로고
    • Improved survival with vemurafenib in melanoma with BRAF V600E mutation
    • Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011;364:2507-16
    • (2011) N Engl J Med , vol.364 , pp. 2507-2516
    • Chapman, P.B.1    Hauschild, A.2    Robert, C.3
  • 5
    • 84863116743 scopus 로고    scopus 로고
    • Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib
    • Sosman JA, Kim KB, Schuchter L, et al. Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib. N Engl J Med 2012;366:707-14
    • (2012) N Engl J Med , vol.366 , pp. 707-714
    • Sosman, J.A.1    Kim, K.B.2    Schuchter, L.3
  • 6
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010;363:711-23
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 7
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated melanoma
    • Robert C, Thomas LO, Bondarenko I, et al. Ipilimumab plus dacarbazine for previously untreated melanoma. N Engl J Med 2011;364:17-26
    • (2011) N Engl J Med , vol.364 , pp. 17-26
    • Robert, C.1    Thomas, L.O.2    Bondarenko, I.3
  • 8
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • Finn OJ. Cancer immunology. N Engl J Med 2008;358:2704-15
    • (2008) N Engl J Med , vol.358 , pp. 2704-2715
    • Finn, O.J.1
  • 10
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 11
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity anti-PD-L1 antibody inpatients with advanced cancer
    • Brahmer JR, Tykodi SS, Chow LQM, et al. Safety and activity anti-PD-L1 antibody inpatients with advanced cancer. N Engl J Med 2012;366:2455-65
    • (2012) N Engl J Med , vol.366 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Lqm, C.3
  • 12
    • 79960299888 scopus 로고    scopus 로고
    • Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immuotherapy
    • Rosenberg SA, Yang JC, Sherry RM, et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immuotherapy. Clin Cancer Res 2011;17:4550-7
    • (2011) Clin Cancer Res , vol.17 , pp. 4550-4557
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 13
    • 0028205790 scopus 로고
    • Improved survival in stage III melanoma patients with GM2 antibodies: A randomized trial of adjuvant vaccination with GM2 ganglioside
    • Livingston PO, Wong GY, Adluri S, et al. Improved survival in stage III melanoma patients with GM2 antibodies: a randomized trial of adjuvant vaccination with GM2 ganglioside. J Clin Oncol 1994;12:1036-44
    • (1994) J Clin Oncol , vol.12 , pp. 1036-1044
    • Livingston, P.O.1    Wong, G.Y.2    Adluri, S.3
  • 14
    • 0035339880 scopus 로고    scopus 로고
    • High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2- KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: Results of intergroup trial E1694/S9512/ C509801
    • Kirkwood JM, Ibrahim JG, Sosman JA, et al. High-dose interferon alfa-2b significantly prolongs relapse-free and overall survival compared with the GM2- KLH/QS-21 vaccine in patients with resected stage IIB-III melanoma: results of intergroup trial E1694/S9512/ C509801. J Clin Oncol 2001;19:2370-80
    • (2001) J Clin Oncol , vol.19 , pp. 2370-2380
    • Kirkwood, J.M.1    Ibrahim, J.G.2    Sosman, J.A.3
  • 15
    • 78449242173 scopus 로고    scopus 로고
    • E4697: Phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage II-IV melanoma [abstract 8504]
    • Lawson DH, Lee SJ, Tarhini AA, et al. E4697: phase III cooperative group study of yeast-derived granulocyte macrophage colony-stimulating factor (GM-CSF) versus placebo as adjuvant treatment of patients with completely resected stage II-IV melanoma [abstract 8504]. J Clin Oncol 2010;28(Suppl):15s
    • (2010) J Clin Oncol , vol.28 , Issue.SUPPL.
    • Lawson, D.H.1    Lee, S.J.2    Tarhini, A.A.3
  • 16
    • 79957831345 scopus 로고    scopus 로고
    • Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
    • Schwartzentruber DJ, Lawson DH, Richards JM, et al. Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med 2011;364:2119-27
    • (2011) N Engl J Med , vol.364 , pp. 2119-2127
    • Schwartzentruber, D.J.1    Lawson, D.H.2    Richards, J.M.3
  • 17
    • 0028860311 scopus 로고
    • A phase III randomized, double-blind multiinstitutional trial of vaccinia melanomaoncolysate-active specific immunotherapy for patients with stage II melanoma
    • Wallack MK, Sivanandham M, Balch CM, et al. A phase III randomized, double-blind multiinstitutional trial of vaccinia melanomaoncolysate-active specific immunotherapy for patients with stage II melanoma. Cancer 1995;75:34-42
    • (1995) Cancer , vol.75 , pp. 34-42
    • Wallack, M.K.1    Sivanandham, M.2    Balch, C.M.3
  • 18
    • 13144275236 scopus 로고    scopus 로고
    • Surgical adjuvant active specific immunotherapy for patients with stage III melanoma: The final analysis of data from a phase III, randomized, double-blind, multicenter vaccinia melanoma oncolysate trial
    • Wallack MK, Sivanandham M, Balch CM, et al. Surgical adjuvant active specific immunotherapy for patients with stage III melanoma: the final analysis of data from a phase III, randomized, double-blind, multicenter vaccinia melanoma oncolysate trial. J Am Coll Surg 1998;187:69-77
    • (1998) J Am Coll Surg , vol.187 , pp. 69-77
    • Wallack, M.K.1    Sivanandham, M.2    Balch, C.M.3
  • 19
    • 0034772102 scopus 로고    scopus 로고
    • Double-blind trial of a polyvalent, shed-antigen, melanoma vaccine
    • Bystryn JC, Zeleniuch-Jacquotte A, Oratz R, et al. Double-blind trial of a polyvalent, shed-antigen, melanoma vaccine. Clin Cancer Res 2001;7:1882-7
    • (2001) Clin Cancer Res , vol.7 , pp. 1882-1887
    • Bystryn, J.C.1    Zeleniuch-Jacquotte, A.2    Oratz, R.3
  • 20
    • 0037089687 scopus 로고    scopus 로고
    • Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: Overall results of a randomized trial of the Southwest Oncology Group
    • Sondak VK, Liu PY, Tuthill RJ, et al. Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group. J Clin Oncol 2002;20:2058-66
    • (2002) J Clin Oncol , vol.20 , pp. 2058-2066
    • Sondak, V.K.1    Liu, P.Y.2    Tuthill, R.J.3
  • 21
    • 0037108861 scopus 로고    scopus 로고
    • Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: Results of a randomized trial
    • Hersey P, Coates AS, McCarthy WH, et al. Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trial. J Clin Oncol 2002;20:4181-90
    • (2002) J Clin Oncol , vol.20 , pp. 4181-4190
    • Hersey, P.1    Coates, A.S.2    McCarthy, W.H.3
  • 22
    • 34249941065 scopus 로고    scopus 로고
    • Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon alfa-2b compared with high-dose interferon alfa-2b for resected stage III cutaneous melanoma
    • Mitchell MS, Abrams J, Thompson JA, et al. Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon alfa-2b compared with high-dose interferon alfa-2b for resected stage III cutaneous melanoma. J Clin Oncol 2007;25:2078-85
    • (2007) J Clin Oncol , vol.25 , pp. 2078-2085
    • Mitchell, M.S.1    Abrams, J.2    Thompson, J.A.3
  • 23
    • 34548249596 scopus 로고    scopus 로고
    • An international, randomized, phase III trial of bacillus Calmette-Guerin (BCG) plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional or distant sites [abstract 8508]
    • Morton DL, Mozzillo N, Thompson JF, et al. An international, randomized, phase III trial of bacillus Calmette-Guerin (BCG) plus allogeneic melanoma vaccine (MCV) or placebo after complete resection of melanoma metastatic to regional or distant sites [abstract 8508]. J Clin Oncol 2007;25:474s
    • (2007) J Clin Oncol , vol.25
    • Morton, D.L.1    Mozzillo, N.2    Thompson, J.F.3
  • 24
    • 84864008345 scopus 로고    scopus 로고
    • Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis
    • Weide B, Zelba H, Derhovanessian E, et al. Functional T cells targeting NY-ESO-1 or Melan-A are predictive for survival of patients with distant melanoma metastasis. J Clin Oncol 2012;1835-41
    • (2012) J Clin Oncol , pp. 1835-1841
    • Weide, B.1    Zelba, H.2    Derhovanessian, E.3
  • 25
    • 73349133717 scopus 로고    scopus 로고
    • Phase II clinical trial of a grnaulocyte-macrophage colonystimulating factor-endoding, second-generation oncyloytic Herpesvirus in patients with unresectable metastatic melanoma
    • Senzer NN, Kaufman HL, Amatruda T, et al. Phase II clinical trial of a grnaulocyte-macrophage colonystimulating factor-endoding, second-generation oncyloytic Herpesvirus in patients with unresectable metastatic melanoma. J Clin Oncol 2009;27:5763-71
    • (2009) J Clin Oncol , vol.27 , pp. 5763-5771
    • Senzer, N.N.1    Kaufman, H.L.2    Amatruda, T.3
  • 26
    • 77952125524 scopus 로고    scopus 로고
    • Use of GM-CSF as an adjuvant with cancer vaccines: Beneficial or detrimental?
    • Clive KS, Tyler Ja, Clifton GT, et al. Use of GM-CSF as an adjuvant with cancer vaccines: beneficial or detrimental? Expert Rev Vaccines 2010;9:519-25
    • (2010) Expert Rev Vaccines , vol.9 , pp. 519-525
    • Clive, K.S.1    Tyler, J.A.2    Clifton, G.T.3
  • 27
    • 0033998594 scopus 로고    scopus 로고
    • Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colonystimulating factor
    • Spitler LE, Grossbard ML, Ernstoff MS, et al. Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colonystimulating factor. J Clin Oncol 2000;18:1614-21
    • (2000) J Clin Oncol , vol.18 , pp. 1614-1621
    • Spitler, L.E.1    Grossbard, M.L.2    Ernstoff, M.S.3
  • 28
    • 67651151520 scopus 로고    scopus 로고
    • Recombinant human granulocyte-macrophage colonystimulating factor (GM-CSF, sargramostim) administered for 3 years as adjuvant therapy of stages II (T4), III, and IV melanoma
    • Spitler LE, Weber RW, Allen RE, et al. Recombinant human granulocyte-macrophage colonystimulating factor (GM-CSF, sargramostim) administered for 3 years as adjuvant therapy of stages II(T4), III, and IV melanoma. J Immunother 2009;32:632-7
    • (2009) J Immunother , vol.32 , pp. 632-637
    • Spitler, L.E.1    Weber, R.W.2    Allen, R.E.3
  • 29
    • 0642311904 scopus 로고    scopus 로고
    • Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colonystimulating factor in adjuvant or pulsed on dendritic cells
    • Slingluff CL Jr, Petroni GR, Yamshchikov GV, et al. Clinical and immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colonystimulating factor in adjuvant or pulsed on dendritic cells. J Clin Oncol 2003;21:4016-26
    • (2003) J Clin Oncol , vol.21 , pp. 4016-4026
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Yamshchikov, G.V.3
  • 30
    • 0037217054 scopus 로고    scopus 로고
    • Granulocyte-macrophage-colonystimulating factor added to a multipeptide vaccine for resected stage II melanoma
    • Weber J, Sondak VK, Scotland R, et al. Granulocyte-macrophage- colonystimulating factor added to a multipeptide vaccine for resected stage II melanoma. Cancer 2003;97:186-200
    • (2003) Cancer , vol.97 , pp. 186-200
    • Weber, J.1    Sondak, V.K.2    Scotland, R.3
  • 31
    • 0025735629 scopus 로고
    • The dendritic cell system and its role in immunogenicity
    • Steinman R. The dendritic cell system and its role in immunogenicity. Ann Rev Immunol 1991;9:271-96
    • (1991) Ann Rev Immunol , vol.9 , pp. 271-296
    • Steinman, R.1
  • 32
    • 0030781916 scopus 로고    scopus 로고
    • Dendritic cells: Unique leukocyte populations which control the primary immune response
    • Hart DNJ. Dendritic cells: unique leukocyte populations which control the primary immune response. Blood 1997;90:3245-87
    • (1997) Blood , vol.90 , pp. 3245-3287
    • Hart, D.N.J.1
  • 34
    • 71949123992 scopus 로고    scopus 로고
    • Dendritic cell vaccination as a treatment modality for melanoma
    • Eubel J, Enk A. Dendritic cell vaccination as a treatment modality for melanoma. Expert Rev Anticancer Ther 2009;9:1631-42
    • (2009) Expert Rev Anticancer Ther , vol.9 , pp. 1631-1642
    • Eubel, J.1    Enk, A.2
  • 35
    • 24144459856 scopus 로고    scopus 로고
    • Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type 1 interferon
    • Banchereau J, Ueno H, Dhodapkar M, et al. Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells derived from CD34+ progenitors and activated with type 1 interferon. J Immunother 2005;28:505-16
    • (2005) J Immunother , vol.28 , pp. 505-516
    • Banchereau, J.1    Ueno, H.2    Dhodapkar, M.3
  • 36
    • 33645325115 scopus 로고    scopus 로고
    • Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: A randomized phase II trial of the DC study group of the DeCOG
    • Schadendorf D, Ugurel S, Schuler-Thurner B, et al. Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase II trial of the DC study group of the DeCOG. Annal Oncol 2006;17:563-70
    • (2006) Annal Oncol , vol.17 , pp. 563-570
    • Schadendorf, D.1    Ugurel, S.2    Schuler-Thurner, B.3
  • 37
    • 79151468702 scopus 로고    scopus 로고
    • Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used
    • Lesterhuis WJ, Schreibelt G, Scharenborg NM, et al. Wild-type and modified gp100 peptide-pulsed dendritic cell vaccination of advanced melanoma patients can lead to long-term clinical responses independent of the peptide used. Cancer Immunol Immunother 2011;60:249-60
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 249-260
    • Lesterhuis, W.J.1    Schreibelt, G.2    Scharenborg, N.M.3
  • 38
    • 79957904174 scopus 로고    scopus 로고
    • Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma
    • Wilgenhof S, Van Nuffel AM, Corthals J, et al. Therapeutic vaccination with an autologous mRNA electroporated dendritic cell vaccine in patients with advanced melanoma. J Immunother 2011;34:448-56
    • (2011) J Immunother , vol.34 , pp. 448-456
    • Wilgenhof, S.1    Van Nuffel, A.M.2    Corthals, J.3
  • 39
    • 60849084473 scopus 로고    scopus 로고
    • Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing cells
    • Lopez MN, Pereda C, Segal G, et al. Prolonged survival of dendritic cell-vaccinated melanoma patients correlates with tumor-specific delayed type IV hypersensitivity response and reduction of tumor growth factor beta-expressing cells. J Clin Oncol 2009;27:945-52
    • (2009) J Clin Oncol , vol.27 , pp. 945-952
    • Lopez, M.N.1    Pereda, C.2    Segal, G.3
  • 40
    • 77957139474 scopus 로고    scopus 로고
    • Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma
    • Ribas A, Camacho LH, Lee SM, et al. Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma. J Transl Med 2010;8:89
    • (2010) J Transl Med , vol.8 , pp. 89
    • Ribas, A.1    Camacho, L.H.2    Lee, S.M.3
  • 41
    • 77957319524 scopus 로고    scopus 로고
    • Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: Results from a phase I/II trial
    • Trepiakas R, Berntsen A, Hadrup SR, et al. Vaccination with autologous dendritic cells pulsed with multiple tumor antigens for treatment of patients with malignant melanoma: results from a phase I/II trial. Cytother 2010;12:721-34
    • (2010) Cytother , vol.12 , pp. 721-734
    • Trepiakas, R.1    Berntsen, A.2    Hadrup, S.R.3
  • 42
    • 0742269426 scopus 로고    scopus 로고
    • Phase I/II study of treatment with dendritic cell vaccines in patients with disseminated melanoma
    • Hersey P, Menzies SW, Halliday GM, et al. Phase I/II study of treatment with dendritic cell vaccines in patients with disseminated melanoma. Cancer Immunol Immunother 2004;53:125-34
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 125-134
    • Hersey, P.1    Menzies, S.W.2    Halliday, G.M.3
  • 43
    • 42649091526 scopus 로고    scopus 로고
    • Phase I/II study of treatment with matured dendritic cells with or without low dose IL-2 in patients with disseminated melanoma
    • Hersey P, Halliday GM, Farrelly ML, et al. Phase I/II study of treatment with matured dendritic cells with or without low dose IL-2 in patients with disseminated melanoma. Cancer Immunol Immunother 2008;57:1039-51
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1039-1051
    • Hersey, P.1    Halliday, G.M.2    Farrelly, M.L.3
  • 44
    • 0037943937 scopus 로고    scopus 로고
    • Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendrtitic cell vaccine
    • O'Rourke MG, Johnson M, Lanagan C, et al. Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendrtitic cell vaccine. Cancer Immunol Immunother 2003;52:387-95
    • (2003) Cancer Immunol Immunother , vol.52 , pp. 387-395
    • O'Rourke, M.G.1    Johnson, M.2    Lanagan, C.3
  • 45
    • 34648860544 scopus 로고    scopus 로고
    • Dendritic cell immunotherapy for stage IV melanoma
    • O'Rourke MG, Johnson MK, Lanagan CM, et al. Dendritic cell immunotherapy for stage IV melanoma. Melanoma Res 2007;17:316-22
    • (2007) Melanoma Res , vol.17 , pp. 316-322
    • O'Rourke, M.G.1    Johnson, M.K.2    Lanagan, C.M.3
  • 46
    • 48549095277 scopus 로고    scopus 로고
    • Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma
    • Redman BG, Chang AE, Whitfield J, et al. Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma. J Immunother 2008;31:591-8
    • (2008) J Immunother , vol.31 , pp. 591-598
    • Redman, B.G.1    Chang, A.E.2    Whitfield, J.3
  • 47
    • 80955158500 scopus 로고    scopus 로고
    • Dendritic cell-based vaccine in advanced melanoma: Update of clinical outcome
    • Ridolfi L, Petrini M, Fiammenghi L, et al. Dendritic cell-based vaccine in advanced melanoma: update of clinical outcome. Melanoma Res 2011;21:524-9
    • (2011) Melanoma Res , vol.21 , pp. 524-529
    • Ridolfi, L.1    Petrini, M.2    Fiammenghi, L.3
  • 48
    • 0037024461 scopus 로고    scopus 로고
    • Cancer immunotherapy with peptide-based vaccines what have we achieved? Where are we going?
    • Parmiani G, Castelli C, Dalerba P, et al. Cancer immunotherapy with peptide-based vaccines: what have we achieved? Where are we going? J Natl Cancer Inst 2002;94:805-18
    • (2002) J Natl Cancer Inst , vol.94 , pp. 805-818
    • Parmiani, G.1    Castelli, C.2    Dalerba, P.3
  • 49
    • 0033949981 scopus 로고    scopus 로고
    • Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma
    • Kawakami Y, Dang N, Wang X, et al. Recognition of shared melanoma antigens in association with major HLA-A alleles by tumor infiltrating T lymphocytes from 123 patients with melanoma. J Immunother 2000;23:17-27
    • (2000) J Immunother , vol.23 , pp. 17-27
    • Kawakami, Y.1    Dang, N.2    Wang, X.3
  • 51
    • 7444242049 scopus 로고    scopus 로고
    • M-Vax: An autologous, hapten-modified vaccine for human cancer
    • Berd D. M-Vax: an autologous, hapten-modified vaccine for human cancer. Expert Rev Vaccines 2004;3:521-7
    • (2004) Expert Rev Vaccines , vol.3 , pp. 521-527
    • Berd, D.1
  • 52
    • 0025147441 scopus 로고
    • Treatment of metastatic melanoma with an autologous tumor-cell vaccine: Clinical and immunologic results in 64 patients
    • Berd D, Maguire HC Jr, McCue P, et al. treatment of metastatic melanoma with an autologous tumor-cell vaccine: clinical and immunologic results in 64 patients. J Clin Oncol 1990;8:1858-67
    • (1990) J Clin Oncol , vol.8 , pp. 1858-1867
    • Berd, D.1    Maguire Jr., H.C.2    McCue, P.3
  • 53
    • 0030986643 scopus 로고    scopus 로고
    • Autologous hapten-modified melanoma vaccine as postsurgical adjuvant treatment after resection of nodal metastases
    • Berd D, Maguire HC Jr, Schuchter LM, et al. Autologous hapten-modified melanoma vaccine as postsurgical adjuvant treatment after resection of nodal metastases. J Clin Oncol 1997;15:2359-70
    • (1997) J Clin Oncol , vol.15 , pp. 2359-2370
    • Berd, D.1    Maguire Jr., H.C.2    Schuchter, L.M.3
  • 54
    • 39749186213 scopus 로고    scopus 로고
    • Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: The C-100-21 Study Group
    • Testori A, Richards J, Whitman E, et al. Phase III comparison of vitespen, an autologous tumor-derived heat shock protein gp96 peptide complex vaccine, with physician's choice of treatment for stage IV melanoma: the C-100-21 Study Group. J Clin Oncol 2008;26:955-62
    • (2008) J Clin Oncol , vol.26 , pp. 955-962
    • Testori, A.1    Richards, J.2    Whitman, E.3
  • 55
    • 77956609259 scopus 로고    scopus 로고
    • Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications
    • Kyrgidis A, Tzellos T-G, Triaridis S. Melanoma: stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications. J Carcinogen 2010;9:3
    • (2010) J Carcinogen , vol.9 , pp. 3
    • Kyrgidis, A.1    Tzellos, T.-G.2    Triaridis, S.3
  • 57
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: Two faces of eve
    • Clarke MF, Fuller M. Stem cells and cancer: two faces of eve. Cell 2006;124:1111-15
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 58
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature 1994;367:645-8
    • (1994) Nature , vol.367 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3
  • 59
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008;8:755-68
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 61
  • 62
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature 2006;444:756-60
    • (2006) Nature , vol.444 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3
  • 63
    • 79955543814 scopus 로고    scopus 로고
    • Melanoma stem cells: Not rare, but well done
    • Girouard SD, Murphy GF. Melanoma stem cells: not rare, but well done. Lab Invest 2011;91:647-64
    • (2011) Lab Invest , vol.91 , pp. 647-664
    • Girouard, S.D.1    Murphy, G.F.2
  • 64
    • 0036812659 scopus 로고    scopus 로고
    • Analysis of the B-cell repertoire against antigens expressed by human neoplasms
    • Preuss KD, Zwick C, Bormann C, et al. Analysis of the B-cell repertoire against antigens expressed by human neoplasms. Immunol Rev 2002;188:43-50
    • (2002) Immunol Rev , vol.188 , pp. 43-50
    • Preuss, K.D.1    Zwick, C.2    Bormann, C.3
  • 65
    • 33645510439 scopus 로고    scopus 로고
    • New concepts in tumor antigens: Their significance in future immunotherapies for tumors
    • Yang F, Yang XF. New concepts in tumor antigens: their significance in future immunotherapies for tumors. Cell Mol Immunol 2005;2:331-41
    • (2005) Cell Mol Immunol , vol.2 , pp. 331-341
    • Yang, F.1    Yang, X.F.2
  • 66
    • 34548075271 scopus 로고    scopus 로고
    • Immunology of stem cells and cancer stem cells
    • Yang XF. Immunology of stem cells and cancer stem cells. Cell Mol Immunol 2007;4:161-71
    • (2007) Cell Mol Immunol , vol.4 , pp. 161-171
    • Yang, X.F.1
  • 67
    • 0036852241 scopus 로고    scopus 로고
    • Cancer immunoediting: From immunosurveillance to tumor escape
    • Dunn GP, Bruce AT, Ikeda H, et al. Cancer immunoediting: from immunosurveillance to tumor escape. Nat Immunol 2002;3:991-8
    • (2002) Nat Immunol , vol.3 , pp. 991-998
    • Dunn, G.P.1    Bruce, A.T.2    Ikeda, H.3
  • 68
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn GP, Old LJ, Schreiber RD. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 2004;21:137-48
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 69
    • 21844459726 scopus 로고    scopus 로고
    • Cancer vaccines 2004 opening address: The molecular and cellular basis of cancer immunosurveillance and immunoediting
    • Schreiber RD. Cancer vaccines 2004 opening address: the molecular and cellular basis of cancer immunosurveillance and immunoediting. Cancer Immun 2005;5(Suppl 1):1
    • (2005) Cancer Immun , vol.5 , Issue.SUPPL. 1 , pp. 1
    • Schreiber, R.D.1
  • 70
    • 79955791267 scopus 로고    scopus 로고
    • Immunological properties of embryonic and adult stem cells
    • Bifari F, Pacelli L, Krampera M. Immunological properties of embryonic and adult stem cells. World J Stem Cells 2010;2:50-60
    • (2010) World J Stem Cells , vol.2 , pp. 50-60
    • Bifari, F.1    Pacelli, L.2    Krampera, M.3
  • 71
    • 79954998528 scopus 로고    scopus 로고
    • Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function
    • Ramgolam K, Lauriol J, Lalou C, et al. Melanoma spheroids grown under neural crest cell conditions are highly plastic migratory/invasive tumor cells endowed with immunomodulator function. PLoS One 2011;6:e18784
    • (2011) PLoS One , vol.6
    • Ramgolam, K.1    Lauriol, J.2    Lalou, C.3
  • 72
    • 0027220719 scopus 로고
    • Establishing in vitro cultures of autologous tumor cells for use in active specific immunotherapy
    • Dillman RO, Nayak SK, Beutel L. Establishing in vitro cultures of autologous tumor cells for use in active specific immunotherapy. J Immunother 1993;14:65-9
    • (1993) J Immunother , vol.14 , pp. 65-69
    • Dillman, R.O.1    Nayak, S.K.2    Beutel, L.3
  • 73
    • 0000374096 scopus 로고
    • Establishment of multiple tumor cell lines from a patient with melanoma: A simple method to control fibroblast growth
    • Nayak SK, Dillman RO. Establishment of multiple tumor cell lines from a patient with melanoma: a simple method to control fibroblast growth. Clin Biotechnol 1991;3:237-42
    • (1991) Clin Biotechnol , vol.3 , pp. 237-242
    • Nayak, S.K.1    Dillman, R.O.2
  • 74
    • 77954657541 scopus 로고    scopus 로고
    • Establishment of stable cell lines for personalized melanoma cell vaccine
    • Selvan SR, Carbonell DJ, Fowler AW, et al. Establishment of stable cell lines for personalized melanoma cell vaccine. Melanoma Res 2010;20:280-92
    • (2010) Melanoma Res , vol.20 , pp. 280-292
    • Selvan, S.R.1    Carbonell, D.J.2    Fowler, A.W.3
  • 75
    • 79960031452 scopus 로고    scopus 로고
    • Characterization of interferon-gamma-treated melanoma tumor cells for use in dendritic cell-based immunotherapy
    • Cornforth AN, Fowler AW, Carbonell DJ, et al. Characterization of interferon-gamma-treated melanoma tumor cells for use in dendritic cell-based immunotherapy. Cancer Biother Radiopharm 2011;26:345-51
    • (2011) Cancer Biother Radiopharm , vol.26 , pp. 345-351
    • Cornforth, A.N.1    Fowler, A.W.2    Carbonell, D.J.3
  • 76
    • 79954617310 scopus 로고    scopus 로고
    • Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth
    • Civenni G, Walter A, Kobert N, et al. Human CD271-positive melanoma stem cells associated with metastasis establish tumor heterogeneity and long-term growth. Cancer Res 2011;71:3098-109
    • (2011) Cancer Res , vol.71 , pp. 3098-3109
    • Civenni, G.1    Walter, A.2    Kobert, N.3
  • 77
    • 0032969463 scopus 로고    scopus 로고
    • Influence of MUC18/ MCAM/CD146 expression on human melanoma growth and metastasis in SCID mice
    • Schlagbauer-Wadl H, Jansen B, Muller M, et al. Influence of MUC18/ MCAM/CD146 expression on human melanoma growth and metastasis in SCID mice. Int J Cancer 1999;81:951-5
    • (1999) Int J Cancer , vol.81 , pp. 951-955
    • Schlagbauer-Wadl, H.1    Jansen, B.2    Muller, M.3
  • 78
    • 38449109644 scopus 로고    scopus 로고
    • Stem cell-like cancer cells in cancer cell lines
    • Kondo T. Stem cell-like cancer cells in cancer cell lines. Cancer Biomark 2007;3:245-50
    • (2007) Cancer Biomark , vol.3 , pp. 245-250
    • Kondo, T.1
  • 79
    • 34447519095 scopus 로고    scopus 로고
    • Patient-specific vaccines derived from autologous tumor cell lines as active specific immunotherapy: Results of exploratory phase I/II trials in patients with metastatic melanoma
    • Dillman RO, DePriest C, de Leon C, et al. Patient-specific vaccines derived from autologous tumor cell lines as active specific immunotherapy: results of exploratory phase I/II trials in patients with metastatic melanoma. Cancer Biother Radiopharm 2007;22:309-21
    • (2007) Cancer Biother Radiopharm , vol.22 , pp. 309-321
    • Dillman, R.O.1    Depriest, C.2    De Leon, C.3
  • 80
    • 67650826075 scopus 로고    scopus 로고
    • Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific anti-tumor vaccines in patients with metastatic melanoma: Final Report
    • Dillman RO, Selvan SR, Schiltz PM, et al. Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific anti-tumor vaccines in patients with metastatic melanoma: final Report. Cancer Biother Radiopharm 2009;24:311-19
    • (2009) Cancer Biother Radiopharm , vol.24 , pp. 311-319
    • Dillman, R.O.1    Selvan, S.R.2    Schiltz, P.M.3
  • 81
    • 33748684598 scopus 로고    scopus 로고
    • Patient-specific dendritic cell vaccines for metastatic melanoma
    • Dillman RO, Selvan SR, Schlitz PM. Patient-specific dendritic cell vaccines for metastatic melanoma. N Engl J Med 2006;355:1179-81
    • (2006) N Engl J Med , vol.355 , pp. 1179-1181
    • Dillman, R.O.1    Selvan, S.R.2    Schlitz, P.M.3
  • 82
    • 79953744706 scopus 로고    scopus 로고
    • Resistance to the proapoptotic effects of interferon-gamma on melanoma cells used in patient-specific dendritic cell immunotherapy is associated with improved overall survival
    • Cornforth AN, Fowler AW, Carbonell DJ, et al. Resistance to the proapoptotic effects of interferon-gamma on melanoma cells used in patient-specific dendritic cell immunotherapy is associated with improved overall survival. Cancer Immunol Immunother 2011;60:123-31
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 123-131
    • Cornforth, A.N.1    Fowler, A.W.2    Carbonell, D.J.3
  • 83
    • 80051734669 scopus 로고    scopus 로고
    • Features associated with survival in metastatic melanoma patients treated with patient-specific vaccines consisting of proliferating autologous tumor cells and autologous dendritic cells
    • Dillman RO, Fogel GB, Cornforth AN, et al. Features associated with survival in metastatic melanoma patients treated with patient-specific vaccines consisting of proliferating autologous tumor cells and autologous dendritic cells. Cancer Biother Radiopharm 2011;26:407-15
    • (2011) Cancer Biother Radiopharm , vol.26 , pp. 407-415
    • Dillman, R.O.1    Fogel, G.B.2    Cornforth, A.N.3
  • 84
    • 84866665586 scopus 로고    scopus 로고
    • Tumor stem cell antigens as consolidative active specific immunotherapy: A randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma
    • Dillman RO, Cornforth AN, DePriest C, et al. Tumor stem cell antigens as consolidative active specific immunotherapy: a randomized phase II trial of dendritic cells versus tumor cells in patients with metastatic melanoma. J Immunother 2012;35:641-9
    • (2012) J Immunother , vol.35 , pp. 641-649
    • Dillman, R.O.1    Cornforth, A.N.2    Depriest, C.3
  • 85
    • 77958183517 scopus 로고    scopus 로고
    • Durable complete response of refractory, progressing metastatic melanoma after treatment with a patient-specific vaccine
    • Dillman RO, Nanci AA, Williams ST, et al. Durable complete response of refractory, progressing metastatic melanoma after treatment with a patient-specific vaccine. Cancer Biother Radiopharm 2010;25:553-7
    • (2010) Cancer Biother Radiopharm , vol.25 , pp. 553-557
    • Dillman, R.O.1    Nanci, A.A.2    Williams, S.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.