메뉴 건너뛰기




Volumn 143, Issue 4, 2013, Pages 971-977

Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; MESSENGER RNA;

EID: 84876008413     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1378/chest.12-2026     Document Type: Article
Times cited : (66)

References (39)
  • 1
    • 60649108824 scopus 로고    scopus 로고
    • Cardiovascular complications of obstructive sleep apnea syndrome: Evidence from children
    • Bhattacharjee R, Kheirandish-Gozal L, Pillar G, Gozal D. Cardiovascular complications of obstructive sleep apnea syndrome: evidence from children. Prog Cardiovasc Dis. 2009; 51 (5): 416 - 433.
    • (2009) Prog Cardiovasc Dis , vol.51 , Issue.5 , pp. 416-433
    • Bhattacharjee, R.1    Kheirandish-Gozal, L.2    Pillar, G.3    Gozal, D.4
  • 2
    • 43849101079 scopus 로고    scopus 로고
    • Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children
    • Gozal D, Capdevila OS, Kheirandish-Gozal L. Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children. Am J Respir Crit Care Med. 2008; 177 (10): 1142 - 1149.
    • (2008) Am J Respir Crit Care Med. , vol.177 , Issue.10 , pp. 1142-1149
    • Gozal, D.1    Capdevila, O.S.2    Kheirandish-Gozal, L.3
  • 3
    • 52149086125 scopus 로고    scopus 로고
    • Sleep apnea and cardiovascular disease: An American Heart Association
    • Somers VK, White DP, Amin R, et al American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology; American Heart Association Stroke Council; American Heart Association Council on Cardiovascular Nursing; American College of Cardiology Foundation. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation scientific statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. In Collaboration with the National Heart, Lung, and Blood Institute National Center on Sleep Disorders Research (National Institutes of Health). Circulation. 2008; 118 (10): 1080 - 1111.
    • (2008) Circulation. , vol.118 , Issue.10 , pp. 1080-1111
    • Somers, V.K.1    White, D.P.2    Amin, R.3
  • 4
    • 0034700285 scopus 로고    scopus 로고
    • Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea
    • Kato M, Roberts-Thomson P, Phillips BG, et al. Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea. Circulation. 2000; 102 (21): 2607 - 2610.
    • (2000) Circulation , vol.102 , Issue.21 , pp. 2607-2610
    • Kato, M.1    Roberts-Thomson, P.2    Phillips, B.G.3
  • 5
    • 36049051681 scopus 로고    scopus 로고
    • Obstructive sleep apnea and endothelial function in school-aged nonobese children: Effect of adenotonsillectomy
    • Gozal D, Kheirandish-Gozal L, Serpero LD, Sans Capdevila O, Dayyat E. Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy. Circulation. 2007; 116 (20): 2307 - 2314.
    • (2007) Circulation. , vol.116 , Issue.20 , pp. 2307-2314
    • Gozal, D.1    Kheirandish-Gozal, L.2    Serpero, L.D.3    Sans Capdevila, O.4    Dayyat, E.5
  • 6
    • 77649135513 scopus 로고    scopus 로고
    • Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing
    • Bhattacharjee R, Alotaibi WH, Kheirandish-Gozal L, Capdevila OS, Gozal D. Endothelial dysfunction in obese non-hypertensive children without evidence of sleep disordered breathing. BMC Pediatr. 2010; 10 : 8.
    • (2010) BMC Pediatr , vol.10 , pp. 8
    • Bhattacharjee, R.1    Alotaibi, W.H.2    Kheirandish-Gozal, L.3    Capdevila, O.S.4    Gozal, D.5
  • 7
    • 84863229469 scopus 로고    scopus 로고
    • Endothelial dysfunction in children without hypertension: Potential contributions of obesity and obstructive sleep apnea
    • Bhattacharjee R, Kim J, Alotaibi WH, Kheirandish-Gozal L, Capdevila OS, Gozal D. Endothelial dysfunction in children without hypertension: potential contributions of obesity and obstructive sleep apnea. Chest. 2012; 141 (3): 682 - 691.
    • (2012) Chest , vol.141 , Issue.3 , pp. 682-691
    • Bhattacharjee, R.1    Kim, J.2    Alotaibi, W.H.3    Kheirandish-Gozal, L.4    Capdevila, O.S.5    Gozal, D.6
  • 8
    • 80051500579 scopus 로고    scopus 로고
    • Circulating microparticles in children with sleep disordered breathing
    • Kim J, Bhattacharjee R, Kheirandish-Gozal L, Spruyt K, Gozal D. Circulating microparticles in children with sleep disordered breathing. Chest. 2011; 140 (2): 408 - 417.
    • (2011) Chest , vol.140 , Issue.2 , pp. 408-417
    • Kim, J.1    Bhattacharjee, R.2    Kheirandish-Gozal, L.3    Spruyt, K.4    Gozal, D.5
  • 9
    • 27644445989 scopus 로고    scopus 로고
    • The relationship between shear stress and flow-mediated dilatation: Implications for the assessment of endothelial function
    • Pyke KE, Tschakovsky ME. The relationship between shear stress and flow-mediated dilatation: implications for the assessment of endothelial function. J Physiol. 2005; 568 (Pt 2): 357 - 369.
    • (2005) J Physiol , vol.568 , Issue.PART 2 , pp. 357-369
    • Pyke, K.E.1    Tschakovsky, M.E.2
  • 10
    • 78651308651 scopus 로고    scopus 로고
    • Assessment of flow-mediated dilation in humans: A methodological and physiolog-ical guideline
    • Thijssen DH, Black MA, Pyke KE, et al. Assessment of flow-mediated dilation in humans: a methodological and physiolog-ical guideline. Am J Physiol Heart Circ Physiol. 2011; 300 (1): H2 - H12.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , Issue.1
    • Thijssen, D.H.1    Black, M.A.2    Pyke, K.E.3
  • 11
    • 30744458814 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase: Insight into cell-specific gene regulation in the vascular endothelium
    • Fish JE, Marsden PA. Endothelial nitric oxide synthase: insight into cell-specific gene regulation in the vascular endothelium. Cell Mol Life Sci. 2006; 63 (2): 144 - 162.
    • (2006) Cell Mol Life Sci , vol.63 , Issue.2 , pp. 144-162
    • Fish, J.E.1    Marsden, P.A.2
  • 12
    • 74049085411 scopus 로고    scopus 로고
    • Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones
    • Fish JE, Yan MS, Matouk CC, et al. Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones. J Biol Chem. 2010; 285 (2): 810 - 826.
    • (2010) J Biol Chem , vol.285 , Issue.2 , pp. 810-826
    • Fish, J.E.1    Yan, M.S.2    Matouk, C.C.3
  • 13
    • 4544225646 scopus 로고    scopus 로고
    • The cell-specific expression of endothelial nitric-oxide synthase: A role for DNA methylation
    • Chan Y, Fish JE, D'Abreo C, et al. The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation. J Biol Chem. 2004; 279 (33): 35087 - 35100.
    • (2004) J Biol Chem , vol.279 , Issue.33 , pp. 35087-35100
    • Chan, Y.1    Fish, J.E.2    D'Abreo, C.3
  • 14
    • 21644485961 scopus 로고    scopus 로고
    • The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code
    • Fish JE, Matouk CC, Rachlis A, et al. The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code. J Biol Chem. 2005; 280 (26): 24824 - 24838.
    • (2005) J Biol Chem , vol.280 , Issue.26 , pp. 24824-24838
    • Fish, J.E.1    Matouk, C.C.2    Rachlis, A.3
  • 15
    • 18144416929 scopus 로고    scopus 로고
    • Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase
    • Gan Y, Shen YH, Wang J, et al. Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase. J Biol Chem. 2005; 280 (16): 16467 - 16475.
    • (2005) J Biol Chem , vol.280 , Issue.16 , pp. 16467-16475
    • Gan, Y.1    Shen, Y.H.2    Wang, J.3
  • 16
    • 51849162882 scopus 로고    scopus 로고
    • Efficient differentiation of hESCs into endothelial cells in vitro is secured by epigenetic changes
    • Lagarkova MA, Volchkov PY, Philonenko ES, Kiselev SL. Efficient differentiation of hESCs into endothelial cells in vitro is secured by epigenetic changes. Cell Cycle. 2008; 7 (18): 2929 - 2935.
    • (2008) Cell Cycle , vol.7 , Issue.18 , pp. 2929-2935
    • Lagarkova, M.A.1    Volchkov, P.Y.2    Philonenko, E.S.3    Kiselev, S.L.4
  • 17
    • 81355160424 scopus 로고    scopus 로고
    • Epigenetic regulation of endothelial lineage committed genes in proangiogenic hematopoietic and endothelial progenitor cells
    • Ohtani K, Vlachojannis GJ, Koyanagi M, et al. Epigenetic regulation of endothelial lineage committed genes in proangiogenic hematopoietic and endothelial progenitor cells. Circ Res. 2011; 109 (11): 1219 - 1229.
    • (2011) Circ Res , vol.109 , Issue.11 , pp. 1219-1229
    • Ohtani, K.1    Vlachojannis, G.J.2    Koyanagi, M.3
  • 18
    • 22344439276 scopus 로고    scopus 로고
    • Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells
    • Rössig L, Urbich C, Brühl T, et al. Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells. J Exp Med. 2005; 201 (11): 1825 - 1835.
    • (2005) J Exp Med , vol.201 , Issue.11 , pp. 1825-1835
    • Rössig, L.1    Urbich, C.2    Brühl, T.3
  • 20
    • 79957834770 scopus 로고    scopus 로고
    • Epigenetic gene promoter methylation at birth is associated with child's later adiposity
    • Godfrey KM, Sheppard A, Gluckman PD, et al. Epigenetic gene promoter methylation at birth is associated with child's later adiposity. Diabetes. 2011; 60 (5): 1528 - 1534.
    • (2011) Diabetes , vol.60 , Issue.5 , pp. 1528-1534
    • Godfrey, K.M.1    Sheppard, A.2    Gluckman, P.D.3
  • 21
    • 84857047342 scopus 로고    scopus 로고
    • Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content
    • Harvey NC, Lillycrop KA, Garratt E, et al. Evaluation of methylation status of the eNOS promoter at birth in relation to childhood bone mineral content. Calcif Tissue Int. 2012; 90 (2): 120 - 127.
    • (2012) Calcif Tissue Int , vol.90 , Issue.2 , pp. 120-127
    • Harvey, N.C.1    Lillycrop, K.A.2    Garratt, E.3
  • 22
    • 84863012875 scopus 로고    scopus 로고
    • DNA methylation in inflammatory genes among children with obstructive sleep apnea
    • Kim J, Bhattacharjee R, Khalyfa A, et al. DNA methylation in inflammatory genes among children with obstructive sleep apnea. Am J Respir Crit Care Med. 2012; 185 (3): 330 - 338.
    • (2012) Am J Respir Crit Care Med , vol.185 , Issue.3 , pp. 330-338
    • Kim, J.1    Bhattacharjee, R.2    Khalyfa, A.3
  • 23
    • 0003408849 scopus 로고    scopus 로고
    • US Centers For Disease Control And Prevention Website. Accessed July 2, 2012.
    • US Centers for Disease Control and Prevention, National Health Center for Statistics. Growth charts. US Centers for Disease Control and Prevention website. www.cdc.gov/growthcharts. Accessed July 2, 2012.
    • Growth Charts
  • 24
    • 33645021995 scopus 로고    scopus 로고
    • Polysomnographic characteristics in normal preschool and early school-aged children
    • Montgomery-Downs HE, O'Brien LM, Gulliver TE, Gozal D. Polysomnographic characteristics in normal preschool and early school-aged children. Pediatrics. 2006; 117 (3): 741 - 753.
    • (2006) Pediatrics , vol.117 , Issue.3 , pp. 741-753
    • Montgomery-Downs, H.E.1    O'Brien, L.M.2    Gulliver, T.E.3    Gozal, D.4
  • 25
    • 0028930988 scopus 로고
    • Changes in postocclusive reactive hyperaemic values as measured with laser Doppler fluxmetry after infrainguinal arterial reconstructions
    • Wahlberg E, Olofsson P, Swedenborg J, Fagrell B. Changes in postocclusive reactive hyperaemic values as measured with laser Doppler fluxmetry after infrainguinal arterial reconstructions. Eur J Vasc Endovasc. 1995; 9 (2): 197 - 203.
    • (1995) Eur J Vasc Endovasc. , vol.9 , Issue.2 , pp. 197-203
    • Wahlberg, E.1    Olofsson, P.2    Swedenborg, J.3    Fagrell, B.4
  • 26
    • 0033613842 scopus 로고    scopus 로고
    • Characterization of the human endothelial nitric-oxide synthase promoter
    • Karantzoulis-Fegaras F, Antoniou H, Lai SL, et al. Characterization of the human endothelial nitric-oxide synthase promoter. J Biol Chem. 1999; 274 (5): 3076 - 3093.
    • (1999) J Biol Chem , vol.274 , Issue.5 , pp. 3076-3093
    • Karantzoulis-Fegaras, F.1    Antoniou, H.2    Lai, S.L.3
  • 27
    • 0027183208 scopus 로고
    • Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene
    • Marsden PA, Heng HH, Scherer SW, et al. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem. 1993; 268(23): 17478 - 17488.
    • (1993) J Biol Chem. , vol.268 , Issue.23 , pp. 17478-17488
    • Marsden, P.A.1    Heng, H.H.2    Scherer, S.W.3
  • 28
    • 34547111797 scopus 로고    scopus 로고
    • Cyclooxygenase and nitric oxide synthase dependence of cutaneous reactive hyperemia in humans
    • Medow MS, Taneja I, Stewart JM. Cyclooxygenase and nitric oxide synthase dependence of cutaneous reactive hyperemia in humans. Am J Physiol Heart Circ Physiol. 2007; 293 (1): H425 - H432.
    • (2007) Am J Physiol Heart Circ Physiol. , vol.293 , Issue.1
    • Medow, M.S.1    Taneja, I.2    Stewart, J.M.3
  • 29
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol. 1986; 250 (6 Pt 2): H1145 - H1149.
    • (1986) Am J Physiol. , vol.250 , Issue.6 PART 2
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 30
    • 36248958752 scopus 로고    scopus 로고
    • Human cutaneous reactive hyperaemia: Role of BKCa channels and sensory nerves
    • Lorenzo S, Minson CT. Human cutaneous reactive hyperaemia: role of BKCa channels and sensory nerves. J Physiol. 2007; 585 (Pt 1): 295 - 303.
    • (2007) J Physiol , vol.585 , Issue.PART 1 , pp. 295-303
    • Lorenzo, S.1    Minson, C.T.2
  • 31
    • 34247608135 scopus 로고    scopus 로고
    • Endothelial dysfunction is related to insulin resistance and inflammatory biomarker levels in obese prepubertal children
    • Valle Jiménez M, Estepa RM, Camacho RMM, Estrada RC, Luna FG, Guitarte FB. Endothelial dysfunction is related to insulin resistance and inflammatory biomarker levels in obese prepubertal children. Eur J Endocrinol. 2007; 156(4): 497- 502.
    • (2007) Eur J Endocrinol. , vol.156 , Issue.4 , pp. 497-502
    • Valle Jiménez, M.1    Estepa, R.M.2    Camacho, R.M.M.3    Estrada, R.C.4    Luna, F.G.5    Guitarte, F.B.6
  • 33
    • 84862095131 scopus 로고    scopus 로고
    • Gene regulation in the vascular endothelium: Why epigenetics is important for the kidney
    • Jamal A, Man HSJ, Marsden PA. Gene regulation in the vascular endothelium: why epigenetics is important for the kidney. Semin Nephrol. 2012; 32 (2): 176 - 184.
    • (2012) Semin Nephrol. , vol.32 , Issue.2 , pp. 176-184
    • Jamal, A.1    Man, H.S.J.2    Marsden, P.A.3
  • 34
    • 79959209876 scopus 로고    scopus 로고
    • Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism
    • Advani A, Huang QL, Thai K, et al. Long-term administration of the histone deacetylase inhibitor vorinostat attenuates renal injury in experimental diabetes through an endothelial nitric oxide synthase-dependent mechanism. Am J Pathol. 2011; 178 (5): 2205 - 2214.
    • (2011) Am J Pathol , vol.178 , Issue.5 , pp. 2205-2214
    • Advani, A.1    Huang, Q.L.2    Thai, K.3
  • 35
    • 79955055958 scopus 로고    scopus 로고
    • Epigenetics in cardiovascular disease
    • Shirodkar AV, Marsden PA. Epigenetics in cardiovascular disease. Curr Opin Cardiol. 2011; 26 (3): 209 - 215.
    • (2011) Curr Opin Cardiol , vol.26 , Issue.3 , pp. 209-215
    • Shirodkar, A.V.1    Marsden, P.A.2
  • 36
    • 77954325682 scopus 로고    scopus 로고
    • Epigenetics of the vascular endothelium
    • Yan MSC, Matouk CC, Marsden PA. Epigenetics of the vascular endothelium. J Appl Physiol. 2010; 109 (3): 916 - 926.
    • (2010) J Appl Physiol. , vol.109 , Issue.3 , pp. 916-926
    • Yan, M.S.C.1    Matouk, C.C.2    Marsden, P.A.3
  • 37
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev. 2011; 25 (10): 1010 - 1022.
    • (2011) Genes Dev. , vol.25 , Issue.10 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 38
    • 69249220176 scopus 로고    scopus 로고
    • DNA methylation and methyl-CpG binding proteins: Developmental requirements and function
    • Bogdanović O, Veenstra GJ. DNA methylation and methyl-CpG binding proteins: developmental requirements and function. Chromosoma. 2009; 118 (5): 549 - 565.
    • (2009) Chromosoma. , vol.118 , Issue.5 , pp. 549-565
    • Bogdanović, O.1    Veenstra, G.J.2
  • 39
    • 79959521749 scopus 로고    scopus 로고
    • The redox basis of epigenetic modifications: From mechanisms to functional consequences
    • Cyr AR, Domann FE. The redox basis of epigenetic modifications: from mechanisms to functional consequences. Antioxid Redox Signal. 2011; 15 (2): 551 - 589.
    • (2011) Antioxid Redox Signal , vol.15 , Issue.2 , pp. 551-589
    • Cyr, A.R.1    Domann, F.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.