Rapid chemical profiling of saponins in the flower buds of Panax notoginseng by integrating MCI gel column chromatography and liquid chromatography/mass spectrometry analysis

Food Chemistry

Volumn 139, Issue 1-4, 2013, Pages 762-769

  Yang, Wen Zhi ^a   Bo, Tao ^b   Ji, Shuai ^a   Qiao, Xue ^a   Guo, De An ^a   Ye, Min ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b AGILENT TECHNOLOGIES   (China)

Author keywords

Chemical profiling; Flower buds of Panax notoginseng; Liquid chromatography mass spectrometry; Notoginseng saponins

Indexed keywords

CHEMICAL PROFILING; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; GEL COLUMN CHROMATOGRAPHIES; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; NOTOGINSENG SAPONINS; PANAX NOTOGINSENG; STRUCTURAL INFORMATION; TRADITIONAL CHINESE MEDICINE;

ELECTROSPRAY IONIZATION; LIQUIDS; MASS SPECTROMETRY; METABOLITES;

CHROMATOGRAPHY;

GINSENOSIDE; SAPONIN DERIVATIVE;

ARTICLE; BUD; COLUMN CHROMATOGRAPHY; ELECTROSPRAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PANAX; PANAX NOTOGINSENG;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; FLOWERS; GINSENOSIDES; MOLECULAR STRUCTURE; PANAX NOTOGINSENG; SAPONINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

PANAX; PANAX NOTOGINSENG;

EID: 84875966479     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2013.01.051     Document Type: Article

References (25)

1. M. Dan, M.M. Su, X.F. Gao, T. Zhao, A.H. Zhao, and G.X. Xie Metabolite profiling of Panax notoginseng using UPLC-ESI-MS Phytochemistry 69 2010 2237 2244
2. N. Fuzzati, B. Gatetta, K. Jayakar, R. Pace, and F. Peterlongo Liquid chromatography electrospray mass spectrometric identification of ginsenosides in Panax ginseng roots Journal of Chromatography A 854 1999 69 79
3. X.F. Gao, M. Dan, A.H. Zhao, G.X. Xie, and W. Jia Simultaneous determination of saponins in flower buds of Panax notoginseng using high performance liquid chromatography Biomedical Chromatography 22 2008 244 249
4. J. Guan, C.M. Lai, and S.P. Li A rapid method for the simultaneous determination of 11 saponins in Panax notoginseng using ultra performance liquid chromatography Journal of Pharmaceutical and Biomedical Analysis 44 2007 996 1000
5. 2, Rc, and Rd, four new malonylated dammarane-type triterpene oligoglycosides from Ginseng Radix Chemical & Pharmaceutical Bulletin 31 1983 3353 3356
6. G.C. Kite, M.J.R. Howes, C.J. Leon, and M.S.J. Simmonds Liquid chromatography mass spectrometry of malonyl-ginsenosides in the authentication of ginseng Rapid Communications in Mass Spectrometry 17 2003 238 244
7. L. Li, R. Tsao, J.P. Dou, F.R. Song, Z.Q. Liu, and S.Y. Liu Detection of saponins in extract of Panax notoginseng by liquid chromatography electrospray ionization mass spectrometry Analytica Chimica Acta 536 2005 21 28
8. Y.J. Li, H.L. Wei, L.W. Qi, J. Chen, M.T. Ren, and P. Li Characterization and identification of saponins in Achyranthes bidentata by rapid-resolution liquid chromatography with electrospray ionization quadrupole time-of-flight tandem mass spectrometry Rapid Communications in Mass Spectrometry 24 2010 2975 2985
9. S.Y. Liu, M. Cui, Z.Q. Liu, F.R. Song, and W.J. Mo Structural analysis of saponins from medicinal herbs using electrospray ionization tandem mass spectrometry Journal of the American Society for Mass Spectrometry 15 2004 133 141
10. Y.Y. Liu, J.B. Li, J.M. He, Z. Abliz, J. Qu, and S.S. Yu Identification of new trace triterpenoid saponins from the roots of Panax notoginseng by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry Rapid Communications in Mass Spectrometry 23 2009 667 679
11. J.H. Liu, X. Wang, S.Q. Cai, K. Komatsu, and T. Namba Analysis of the constituents in the Chinese drug Notoginseng by liquid chromatography- electrospray mass spectrometry Journal of Chinese Pharmaceutical Sciences 13 2004 224 237
12. L.W. Qi, C.Z. Wang, and C.S. Yuan Isolation and analysis of ginseng: Advances and challenges Natural Product Reports 28 2011 467 495
13. X. Qiao, X. Zhang, M. Ye, Y.F. Su, J. Dong, and J. Han Rapid characterization of triterpene saponins from Conyza blinii by liquid chromatography coupled with mass spectrometry Rapid Communications in Mass Spectrometry 24 2010 3340 3350
14. C.C. Ruan, Z. Liu, X. Li, X. Liu, L.J. Wang, and H.Y. Pan Isolation and characterization of a new ginsenoside from the fresh root of Panax ginseng Molecules 15 2010 2319 2325
15. X.D. Su, N.K. Jacob, R. Amunugama, P.H. Hsu, R. Fishel, and M.A. Freitas Enrichment and characterization of histones by two-dimensional hydroxyapatite/reversed-phase liquid chromatography-mass spectrometry Analytical Biochemistry 388 2009 47 55
16. Y. Wang, X. Lu, and G.W. Xu Development of a comprehensive two-dimensional hydrophilic interaction chromatography/quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria Journal of Chromatography A 1181 2008 51 59
17. J.R. Wang, Y. Yamasaki, T. Tanaka, I. Kouno, and Z.H. Jiang Dammarane-type triterpene saponins from the flowers of Panax notoginseng Molecules 14 2009 2087 2094
18. M. Yang, X.M. Wang, S.H. Guan, J.M. Xia, J.H. Sun, and H. Guo Analysis of triterpenoids in Ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry Journal of the American Society for Mass Spectrometry 18 2007 927 939
19. W.Z. Yang, M. Ye, X. Qiao, C.F. Liu, W.J. Miao, and T. Bo A strategy for efficient discovery of new natural compounds by integrating orthogonal column chromatography and liquid chromatography/mass spectrometry analysis: Its application in Panax ginseng, Panax quinquefolium and Panax notoginseng to characterize 437 potential new ginsenosides Analytica Chimica Acta 739 2012 56 66
20. Q.H. Yin, Y.Q. Zhu, H. Yu, W.B. Zeng, and F.Y. Zhao Advances of chemical constituents from flower buds of Panax notoginseng (Burk) F.H. Chen and its pharmacological effects Chinese Journal of Spectroscopy Laboratory 28 2011 1194 1197
21. M. Yoshikawa, T. Morikawa, Y. Kashima, K. Ninomiya, and H. Matsuda Structures of new dammarane-type triterpene saponins from the flower buds of Panax notoginseng and hepatoprotective effects of principal ginseng saponins Journal of Natural Products 66 2003 922 927
22. M. Yoshikawa, T. Murakami, T. Ueno, N. Hirokawa, K. Yashiro, and N. Murakami Bioactive saponins and glycosides. 9. Notoginseng. 2. Structures of five new dammarane-type triterpene oligoglycosides, notoginsenosides-E, -G, -H, -I, and -J, and a novel acetylenic fatty acid glycoside, notoginsenic acid beta-sophoroside, from the dried root of Panax notoginseng (Burk) F.H. Chen Chemical & Pharmaceutical Bulletin 45 1997 1056 1062
23. M. Yoshikawa, T. Murakami, T. Ueno, K. Yashiro, N. Hirokawa, and N. Murakami Bioactive saponins and glycosides. 8. Notoginseng. 1. New dammarane-type triterpene oligoglycosides, notoginsenosides-A, -B, -C, and -D, from the dried root of Panax notoginseng (Burk) F.H. Chen Chemical & Pharmaceutical Bulletin 45 1997 1039 1045
24. Y.L. Zhang, and D.D. Zuo Progress in the modern research of flower buds of Panax notoginseng Information on Traditional Chinese Medicine 28 2011 116 118
25. G.Y. Zuo, J.X. Wei, Y.C. Du, S.M. Cao, and Y.G. Chen Studies on saponins from flower-buds of Sanchi (Panax notoginseng (Burk) F.H. Chen) Natural Product Research and Development 3 1991 24 30