Immune-mediated inflammatory diseases: Progress in molecular pathogenesis and therapeutic strategies

Expert Review of Clinical Immunology

Volumn 9, Issue 4, 2013, Pages 297-299

  Bayry, Jagadeesh ^a   Radstake, Timothy R ^b  

^a INSERM   (France)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; GAMMA INTERFERON; INFLUENZA VACCINE; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 22; INTERLEUKIN 6; OSTEOGENIC PROTEIN 1; TRANSCRIPTOME; TRANSFORMING GROWTH FACTOR BETA;

ANTISENSE THERAPY; APOPTOSIS; AUTOINFLAMMATORY DISEASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONFERENCE PAPER; CPG ISLAND; DIABETES MELLITUS; DNA METHYLATION; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROSING ALVEOLITIS; FIBROSIS; GENE EXPRESSION; GENE MUTATION; GENE REPLACEMENT THERAPY; GENETIC POLYMORPHISM; HUMAN; IMMUNE MEDIATED INJURY; INNATE IMMUNITY; KIDNEY FIBROSIS; KIDNEY INJURY; LIVER CELL CARCINOMA; LYMPHOID CELL; MOLECULAR INTERACTION; MOLECULAR PATHOLOGY; MULTIPLE SCLEROSIS; MYOFIBROBLAST; PHYSICIAN; PROMOTER REGION; PROTEIN FUNCTION; RETINA DYSTROPHY; RETINA MACULA AGE RELATED DEGENERATION; SCIENTIST; SINGLE NUCLEOTIDE POLYMORPHISM; T LYMPHOCYTE; TH17 CELL; WORKSHOP;

ANIMALS; DIABETES COMPLICATIONS; EYE DISEASES; GENETIC THERAPY; GENOMICS; HUMANS; IMMUNE SYSTEM DISEASES; IMMUNITY, INNATE; INFORMATION DISSEMINATION; INTERDISCIPLINARY COMMUNICATION; MOLECULAR TARGETED THERAPY; MULTIPLE SCLEROSIS; TH17 CELLS;

EID: 84875966316     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/eci.13.10     Document Type: Conference Paper

References (19)

1. Youinou P, Pers JO, Gershwin ME, Shoenfeld Y. Geo-epidemiology and autoimmunity. J. Autoimmun. 34(3), J163-J167 (2010
2. Alzabin S, Venables PJ. Etiology of autoimmune disease: Past, present and future. Expert Rev. Clin. Immunol. 8(2), 111-113 (2012
3. Broen JC, Coenen MJ, Radstake TR. Deciphering the genetic background of systemic sclerosis. Expert Rev. Clin. Immunol. 7(4), 449-462 (2011
4. Diaz-Gallo LM, Martin J. Common genes in autoimmune diseases: A link between immune-mediated diseases. Expert Rev. Clin. Immunol. 8(2), 107-109 (2012
5. Jungel A, Distler JH, Gay S, Distler O. Epigenetic modifications: Novel therapeutic strategies for systemic sclerosis? Expert Rev. Clin. Immunol. 7(4), 475-480 (2011
6. Maddur MS, Vani J, Lacroix-Desmazes S, Kaveri S, Bayry J. Autoimmunity as a predisposition for infectious diseases. PLoS Pathog. 6(11), e1001077 (2010
7. Ibrahim I, Owen SA, Barton A. Genetics and the impact on treatment protocols in patients with rheumatoid arthritis. Expert Rev. Clin. Immunol. 8(6), 509-511 (2012
8. Raza A, Yousaf W, Giannella R, Shata MT. Th17 cells: Interactions with predisposing factors in the immunopathogenesis of inflammatory bowel disease. Expert Rev. Clin. Immunol. 8(2), 161-168 (2012
9. Maddur MS, Miossec P, Kaveri SV, Bayry J. Th17 cells: Biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies. Am. J. Pathol. 181(1), 8-18 (2012
10. Lehmann B, Schwab I, Bohm S, Lux A, Biburger M, Nimmerjahn F. Fc RIIB: A modulator of cell activation and humoral tolerance. Expert Rev. Clin. Immunol. 8(3), 243-254 (2012
11. Herlin T. Tocilizumab for the treatment of systemic juvenile idiopathic arthritis. Expert Rev. Clin. Immunol. 8(6), 517-525 (2012
12. Bayry J. Chemokine axis as a therapeutic target to enhance the recruitment of Tregs and treat organ-specific autoimmune and inflammatory diseases. Immunotherapy 4(1), 9-12 (2012
13. Michels-van Amelsfort JM, Walter GJ, Taams LS. CD4+CD25+ regulatory T cells in systemic sclerosis and other rheumatic diseases. Expert Rev. Clin. Immunol. 7(4), 499-514 (2011
14. Sugimoto H, LeBleu VS, Bosukonda D et al. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat. Med. 18(3), 396-404 (2012
15. Wei L, Liu B, Tuo J et al. Hypomethylation of the IL17RC promoter associates with age-related macular degeneration. Cell Rep. 2(5), 1151-1158 (2012
16. den Hollander AI, Koenekoop RK, Yzer S et al Mutations in the CEP290 (NPHP6 gene are a frequent cause of Leber congenital amaurosis. Am. J. Hum. Genet. 79(3), 556-561 (2006
17. Hayday AC, Peakman M. The habitual, diverse and surmountable obstacles to human immunology research. Nat. Immunol. 9(6), 575-580 (2008
18. Veldhoen M, Hirota K, Westendorf AM et al. The aryl hydrocarbon receptor links Th17-cell-mediated autoimmunity to environmental toxins. Nature 453(7191), 106-109 (2008
19. Li Y, Innocentin S, Withers DR et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell 147(3), 629-640 (2011