Haemoglobin glycation may partly explain the discordance between HbA1c measurement and oral glucose tolerance test to diagnose dysglycaemia in overweight/obese subjects

Diabetes and Metabolism

Volumn 39, Issue 2, 2013, Pages 118-125

  Cosson, E ^a,b   Chiheb, S ^a   Cussac Pillegand, C ^a   Banu, I ^a   Hamo Tchatchouang, E ^a   Nguyen, M T ^a,b   Aout, M ^c   Charnaux, N ^a   Valensi, P ^a  

^a UNIVERSITÉ PARIS 13   (France)

^b Unité de recherche épidémiologique nutritionnelle ^*  (France)

^c HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Diabetes diagnosis; Dysglycaemia diagnosis; Haemoglobin glycation; HbA1c; Obesity; Oral glucose tolerance test

Indexed keywords

FRUCTOSAMINE; HEMOGLOBIN; HEMOGLOBIN A1C;

ARTICLE; COHORT ANALYSIS; DIABETES MELLITUS; DYSGLYCEMIA; GLYCATION; HEMOGLOBIN GLYCATION; HUMAN; HYPERGLYCEMIA; OBESITY; ORAL GLUCOSE TOLERANCE TEST;

ADULT; ANALYSIS OF VARIANCE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; FASTING; FEMALE; FRUCTOSAMINE; GLUCOSE TOLERANCE TEST; HEMOGLOBIN A, GLYCOSYLATED; HEMOGLOBINS; HUMANS; HYPERGLYCEMIA; MALE; MIDDLE AGED; OBESITY; RISK FACTORS;

EID: 84875940015     PISSN: 12623636     EISSN: 18781780     Source Type: Journal    
DOI: 10.1016/j.diabet.2012.08.013     Document Type: Article

References (27)

1. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 1997;20:1183-97.
2. International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes. Diabetes Care 2009;32:1327-34.
3. Sabanayagam C., Liew G., Tai E.S., Shankar A., Lim S.C., Subramaniam T., et al. Relationship between glycated haemoglobin and microvascular complications: is there a natural cut-off point for the diagnosis of diabetes?. Diabetologia 2009, 52:1279-1289.
4. Edelman D., Olsen M.K., Dudley T.K., Harris A.C., Oddone E.Z. Utility of hemoglobin A1c in predicting diabetes risk. J Gen Intern Med 2004, 19:1175-1180.
5. 1c in predicting progression to diabetes in French men and women: data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR). Diabetes Care 2006, 29:1619-1625.
6. Selvin E., Steffes M.W., Zhu H., Matsushita K., Wagenknecht L., Pankow J., et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med 2010, 362:800-811.
7. Diagnosis and classification of diabetes mellitus. Diabetes Care 2011, 34(Suppl. 1):S62-S69. American Diabetes Association.
8. Paulweber B., Valensi P., Lindstrom J., Lalic N.M., Greaves C.J., McKee M., et al. A European evidence-based guideline for the prevention of type 2 diabetes. Horm Metab Res 2010, 42(Suppl. 1):S3-S36.
9. Cosson E., Nguyen M.T., Hamo-Tchatchouang E., Banu I., Chiheb S., Charnaux N., et al. What would be the outcome if the American Diabetes Association recommendations of 2010 had been followed in our practice in 1998-2006?. Diabet Med 2011, 28:567-574.
10. James C., Bullard K.M., Rolka D.B., Geiss L.S., Williams D.E., Cowie C.C., et al. Implications of alternative definitions of prediabetes for prevalence in U.S. adults. Diabetes Care 2011, 34:387-391.
11. Sacks D.B. A1C versus glucose testing: a comparison. Diabetes Care 2011, 34:518-523.
12. Hanas R., John G. 2010 consensus statement on the worldwide standardization of the hemoglobin A1C measurement. Diabetes Care 2010, 33:1903-1904.
13. Roberts W.L., Safar-Pour S., De B.K., Rohlfing C.L., Weykamp C.W., Little R.R. Effects of hemoglobin C and S traits on glycohemoglobin measurements by eleven methods. Clin Chem 2005, 51:776-778.
14. Selvin E., Steffes M.W., Ballantyne C.M., Hoogeveen R.C., Coresh J., Brancati F.L. Racial differences in glycemic markers: a cross-sectional analysis of community-based data. Ann Intern Med 2011, 154:303-309.
15. 1c. Blood 2008, 112:4284-4291.
16. Yudkin J.S., Forrest R.D., Jackson C.A., Ryle A.J., Davie S., Gould B.J. Unexplained variability of glycated haemoglobin in non-diabetic subjects not related to glycaemia. Diabetologia 1990, 33:208-225.
17. Kilpatrick E.S., Maylor P.W., Keevil B.G. Biological variation of glycated hemoglobin. Implications for diabetes screening and monitoring. Diabetes Care 1998, 21:261-264.
18. Mittman N., Desiraju B., Fazil I., Kapupara H., Chattopadhyay J., Jani C.M., et al. Serum fructosamine versus glycosylated hemoglobin as an index of glycemic control, hospitalization, and infection in diabetic hemodialysis patients. Kidney Int Suppl 2010, 117:S41-S45.
19. Cefalu W.T., Bell-Farrow A.D., Petty M., Izlar C., Smith J.A. Clinical validation of a second-generation fructosamine assay. Clin Chem 1991, 37:1252-1256.
20. Van Dieijen-Visser M.P., Seynaeve C., Brombacher P.J. Influence of variations in albumin or total-protein concentration on serum fructosamine concentration. Clin Chem 1986, 32:1610.
21. Lamb E., Venton T.R., Cattell W.R., Dawnay A. Serum glycated albumin and fructosamine in renal dialysis patients. Nephron 1993, 64:82-88.
22. Levey A.S., Bosch J.P., Lewis J.B., Greene T., Rogers N., Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med 1999, 130:461-470. Modification of Diet in Renal Disease Study Group.
23. 1c and fructosamine: evidence for a glycosylation gap and its relation to diabetic nephropathy. Diabetes Care 2003, 26:163-167.
24. 1c in nondiabetic twins. Diabetes Care 2006, 29:1739-1743.
25. Gould B.J., Davie S.J., Yudkin J.S. Investigation of the mechanism underlying the variability of glycated haemoglobin in non-diabetic subjects not related to glycaemia. Clin Chim Acta 1997, 260:49-64.
26. Khera P.K., Joiner C.H., Carruthers A., Lindsell C.J., Smith E.P., Franco R.S., et al. Evidence for interindividual heterogeneity in the glucose gradient across the human red blood cell membrane and its relationship to hemoglobin glycation. Diabetes 2008, 57:2445-2452.
27. Abdul-Ghani M.A., Abdul-Ghani T., Muller G., Bergmann A., Fischer S., Bornstein S., et al. Role of glycated hemoglobin in the prediction of future risk of T2DM. J Clin Endocrinol Metab 2011, 96:2596-2600.