Impact of VEGF-C Gene Polymorphisms and Environmental Factors on Oral Cancer Susceptibility in Taiwan

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Chien, Ming Hsien ^a,b   Liu, Yu Fan ^c   Hsin, Chung Han ^c,d   Lin, Chien Huang ^a   Shih, Chun Han ^b   Yang, Shun Fa ^c,d   Cheng, Chao Wen ^a   Lin, Chiao Wen ^c,d  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; VASCULOTROPIN C;

ADULT; ALCOHOL CONSUMPTION; ARTICLE; BETEL NUT; CANCER RISK; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; GENETIC ASSOCIATION; GENOTYPE ENVIRONMENT INTERACTION; HAPLOTYPE; HETEROZYGOTE; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MOUTH CANCER; MOUTH SQUAMOUS CELL CARCINOMA; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKELESS TOBACCO; SMOKING; TAIWAN; VEGF C GENE; WILD TYPE;

ADULT; AGED; ALLELES; CASE-CONTROL STUDIES; DATABASES, NUCLEIC ACID; ENVIRONMENT; GENE FREQUENCY; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; MOUTH NEOPLASMS; ODDS RATIO; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; TAIWAN; VASCULAR ENDOTHELIAL GROWTH FACTOR C;

PIPER BETEL;

EID: 84875934137     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060283     Document Type: Article

References (49)

1. Chung TT, Pan MS, Kuo CL, Wong RH, Lin CW, et al. (2011) Impact of RECK gene polymorphisms and environmental factors on oral cancer susceptibility and clinicopathologic characteristics in Taiwan. Carcinogenesis 32: 1063-1068.
2. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, et al. (1996) Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 56: 2488-2492.
3. Biolchini F, Pollastri G, Figurelli S, Chiarini L, (2005) Carcinogen metabolism, DNA damage repair and oral head and neck squamocellular carcinoma (HNSCC). A review. Minerva Stomatol 54: 405-414.
4. Nagaraj NS, Beckers S, Mensah JK, Waigel S, Vigneswaran N, et al. (2006) Cigarette smoke condensate induces cytochromes P450 and aldo-keto reductases in oral cancer cells. Toxicol Lett 165: 182-194.
5. Chien MH, Lin CW, Cheng CW, Wen YC, Yang SF, (2013) Matrix metalloproteinase-2 as a target for head and neck cancer therapy. Expert Opin Ther Targets 17: 203-216.
6. Chen MK, Su SC, Lin CW, Tsai CM, Yang SF, et al. (2012) Cathepsin B SNPs elevate the pathological development of oral cancer and raise the susceptibility to carcinogen-mediated oral cancer. Hum Genet 131: 1861-1868.
7. Shastry BS, (2002) SNP alleles in human disease and evolution. J Hum Genet 47: 561-566.
8. Folkman J, (1971) Tumor angiogenesis: therapeutic implications. N Engl J Med 285: 1182-1186.
9. Folkman J, (2002) Role of angiogenesis in tumor growth and metastasis. Semin Oncol 29: 15-18.
10. He Y, Karpanen T, Alitalo K, (2004) Role of lymphangiogenic factors in tumor metastasis. Biochim Biophys Acta 1654: 3-12.
11. Olsson AK, Dimberg A, Kreuger J, Claesson-Welsh L, (2006) VEGF receptor signalling- in control of vascular function. Nat Rev Mol Cell Biol 7: 359-371.
12. Ferrara N, Gerber HP, LeCouter J, (2003) The biology of VEGF and its receptors. Nat Med 9: 669-76.
13. Jeltsch M, Kaipainen A, Joukov V, Meng X, Lakso M, et al. (1997) Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science 276: 1423-1425.
14. Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, et al. (2001) Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med 7: 192-198.
15. Su JL, Yen CJ, Chen PS, Chuang SE, Hong CC, et al. (2007) The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer 96: 541-545.
16. Makinen T, Veikkola T, Mustjoki S, Karpanen T, Catimel B, et al. (2001) Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3. EMBO J 20: 4762-4773.
17. Laakkonen P, Waltari M, Holopainen T, Takahashi T, Pytowski B, et al. (2007) Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res 67: 593-599.
18. Tammela T, Zarkada G, Wallgard E, Murtomäki A, Suchting S, et al. (2008) Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454: 656-660.
19. Li R, Younes M, Wheeler TM, Scardino P, Ohori M, et al. (2004) Expression of vascular endothelial growth factor receptor-3 (VEGFR-3) in human prostate. Prostate 58: 193-199.
20. Su JL, Yang PC, Shih JY, Yang CY, Wei LH, et al. (2006) The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell 9: 209-223.
21. Van Trappen PO, Steele D, Lowe DG, Lowe DG, Baithun S, et al. (2003) Expression of vascular endothelial growth factor (VEGF)-C and VEGF-D, and their receptor VEGFR-3, during different stages of cervical carcinogenesis. J Pathol 201: 544-554.
22. Kodama M, Kitadai Y, Tanaka M, Shinagawa K, Sumida T, et al. (2011) Vascular endothelial growth factor C stimulates progression of human gastric cancer via both autocrine and paracrine mechanisms. Clin Cancer Res 14: 7205-7214.
23. Jennbacken K, Vallbo C, Wang W, Damber JE, (2005) Expression of vascular endothelial growth factor C (VEGF-C) and VEGF receptor-3 in human prostate cancer is associated with regional lymph node metastasis. Prostate 65: 110-116.
24. Warburton G, Nikitakis NG, Roberson P, Marinos NJ, Wu T, et al. (2007) Histopathological and lymphangiogenic parameters in relation to lymph node metastasis in early stage oral squamous cell carcinoma. J Oral Maxillofac Surg 65: 475-484.
25. Yokoyama Y, Charnock-Jones DS, Licence D, Yanaihara A, Hastings JM, et al. (2003) Expression of vascular endothelial growth factor (VEGF)-D and its receptor, VEGF receptor 3, as a prognostic factor in endometrial carcinoma. Clin Cancer Res 9: 1361-1369.
26. Dias S, Choy M, Alitalo K, Rafii S, (2002) Vascular endothelial growth factor (VEGF)-C signaling through FLT-4 (VEGFR-3) mediates leukemic cell proliferation, survival, and resistance to chemotherapy. Blood 99: 2179-2184.
27. Marchio S, Primo L, Pagano M, Palestro G, Albini A, et al. (1999) Vascular endothelial growth factor-C stimulates the migration and proliferation of Kaposi's sarcoma cells. J Biol Chem 274: 27617-27622.
28. Masood R, Kundra A, Zhu S, Xia G, Scalia P, et al. (2003) Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops. Int J Cancer 104: 603-610.
29. Timoshenko AV, Rastogi S, Lala PK, (2007) Migration-promoting role of VEGF-C and VEGF-C binding receptors in human breast cancer cells. Br J Cancer 97: 1090-1098.
30. Cheng CY, Chang CS, Liu CJ, Kao SY, (2008) Vascular endothelial growth factor 936 C/T polymorphism is associated with vascular invasion in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106: 79-84.
31. Schultheis AM, Lurje G, Rhodes KE, Zhang W, Yang D, et al. (2008) Polymorphisms and clinical outcome in recurrent ovarian cancer treated with cyclophosphamide and bevacizumab. Clin Cancer Res 14: 7554-7563.
32. Lurje G, Zhang W, Schultheis AM, Yang D, Groshen S, et al. (2008) Polymorphisms in VEGF and IL-8 predict tumor recurrence in stage III colon cancer. Ann Oncol 19: 1734-1741.
33. Jakubowska A, Gronwald J, Menkiszak J, Górski B, Huzarski T, et al. (2008) The VEGF_936_C>T 3'UTR polymorphism reduces BRCA1-associated breast cancer risk in Polish women. Cancer Lett 262: 71-76.
34. Srinivas SK, Morrison AC, Andrela CM, Elovitz MA (2010) Allelic variations in angiogenic pathway genes are associated with preeclampsia. Am J Obstet Gynecol. 202: 445 e1-11.
35. Hong JM, Kim TH, Kim HJ, Park EK, Yang EK, et al. (2010) Genetic association of angiogenesis- and hypoxia-related gene polymorphisms with osteonecrosis of the femoral head. Exp Mol Med 42: 376-385.
36. Goode EL, Maurer MJ, Sellers TA, Phelan CM, Kalli KR, et al. (2010) Inherited determinants of ovarian cancer survival. Clin Cancer Res 16: 995-1007.
37. Lin MH, Wang CJ, Huang HP, Chou MY, Chou FP, (2004) The tumorigenic characteristics of lime-piper betel quid-transformed JB6 cells. Arch Toxicol 78: 167-173.
38. Lin PY, Yu CH, Wang JT, Chen HH, Cheng SJ, et al. (2008) Expression of hypoxia-inducible factor-1 alpha is significantly associated with the progression and prognosis of oral squamous cell carcinomas in Taiwan. J Oral Pathol Med. 37: 18-25.
39. Inamine M, Nagai Y, Mitsuhashi A, Nagase S, Yaegashi N, et al. (2012) Cigarette smoke stimulates VEGF-C expression in cervical intraepithelial neoplasia (CIN) 1 and 2 lesions. Int J Clin Oncol 17: 498-504.
40. Thorgeirsson SS, Grisham JW, (2002) Molecular pathogenesis of human hepatocellular carcinoma. Nat Genet 31: 339-346.
41. Huang SF, Chen IH, Liao CT, Wang HM, Liou SH, et al. (2009) Combined effects of MDM2 SNP 309 and p53 mutation on oral squamous cell carcinomas associated with areca quid chewing. Oral Oncol 45: 16-22.
42. Lin SC, Liu CJ, Yeh WI, Lui MT, Chang KW, et al. (2006) Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on older male areca (betel) chewers. Cancer Lett 243: 47-54.
43. Chang KW, Lee TC, Yeh WI, Chung MY, Liu CJ, et al. (2004) Polymorphism in heme oxygenase-1 (HO-1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers. Br J Cancer 91: 1551-1555.
44. Weng CJ, Chien MH, Lin CW, Chung TT, Zavras AI, et al. (2010) Effect of CC chemokine ligand 5 and CC chemokine receptor 5 genes polymorphisms on the risk and clinicopathological development of oral cancer. Oral Oncol 46: 767-772.
45. Weng CJ, Lin CW, Chung TT, Tsai CM, Chen MK, et al. (2011) Impact of uPA system gene polymorphisms on the susceptibility of environmental factors to carcinogenesis and the development of clinicopathology of oral cancer. Ann Surg Oncol 18: 805-812.
46. Neuchrist C, Erovic BM, Handisurya A, Fischer MB, Steiner GE, et al. (2003) Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 expression in squamous cell carcinomas of the head and neck. Head Neck 25: 464-474.
47. Fairbrother WG, Chasin LA, (2000) Human genomic sequences that inhibit splicing. Mol Cell Biol 20: 6816-6825.
48. Wang Z, Rolish ME, Yeo G, Tung V, Mawson M, et al. (2004) Systematic identification and analysis of exonic splicing silencers. Cell 119: 831-845.
49. Wagner EJ, Garcia-Blanco MA, (2001) Polypyrimidine tract binding protein antagonizes exon definition. Mol Cell Biol 21: 3281-3288.