Gelsolin activity controls efficient early HIV-1 infection

Retrovirology

Volumn 10, Issue 1, 2013, Pages

  García Expósito, Laura ^a   Ziglio, Serena ^a,b   Barroso González, Jonathan ^a   de Armas Rillo, Laura ^a   Valera, María Soledad ^a   Zipeto, Donato ^b   Machado, José David ^a   Valenzuela Fernández, Agustín ^a  

^a UNIVERSIDAD DE LA LAGUNA   (Spain)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Actin severing activity; Gelsolin; Inhibition of early HIV 1 infection; Perturbed actin dynamics and receptors clustering

Indexed keywords

F ACTIN; GELSOLIN; GLYCOPROTEIN GP 120; VIRUS RECEPTOR;

ARTICLE; CD4+ T LYMPHOCYTE; CELL FUSION; CONTROLLED STUDY; CYTOPLASM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; INFECTION CONTROL; LYMPHOCYTE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PSEUDOPODIUM; SIGNAL TRANSDUCTION; VIRAL TROPISM; VIRUS ENTRY;

ACTINS; ANTIVIRAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE; GELSOLIN; HIV-1; HUMANS; RECEPTORS, HIV; SIGNAL TRANSDUCTION; VIRUS INTERNALIZATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84875929318     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-39     Document Type: Article

References (49)

1. Liu Y, Belkina NV, Shaw S. HIV infection of T cells: actin-in and actin-out. Sci Signal 2009, 2:pe23.
2. Lehmann M, Nikolic DS, Piguet V. How HIV-1 takes advantage of the cytoskeleton during replication and cell-to-cell transmission. Viruses 2011, 3:1757-1776.
3. Blumenthal R, Durell S, Viard M. HIV entry and envelope glycoprotein-mediated fusion. J Biol Chem 2012, 287:40841-40849.
4. Doms RW, Trono D. The plasma membrane as a combat zone in the HIV battlefield. Genes Dev 2000, 14:2677-2688.
5. Kuhmann SE, Platt EJ, Kozak SL, Kabat D. Cooperation of multiple CCR5 coreceptors is required for infections by human immunodeficiency virus type 1. J Virol 2000, 74:7005-7015.
6. Barrero-Villar M, Cabrero JR, Gordon-Alonso M, Barroso-Gonzalez J, Alvarez-Losada S, Munoz-Fernandez MA, Sanchez-Madrid F, Valenzuela-Fernandez A. Moesin is required for HIV-1-induced CD4-CXCR4 interaction, F-actin redistribution, membrane fusion and viral infection in lymphocytes. J Cell Sci 2009, 122:103-113.
7. Jimenez-Baranda S, Gomez-Mouton C, Rojas A, Martinez-Prats L, Mira E, Ana Lacalle R, Valencia A, Dimitrov DS, Viola A, Delgado R. Filamin-A regulates actin-dependent clustering of HIV receptors. Nat Cell Biol 2007, 9:838-846.
8. Yoder A, Yu D, Dong L, Iyer SR, Xu X, Kelly J, Liu J, Wang W, Vorster PJ, Agulto L. HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells. Cell 2008, 134:782-792.
9. Vorster PJ, Guo J, Yoder A, Wang W, Zheng Y, Xu X, Yu D, Spear M, Wu Y. LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection. J Biol Chem 2011, 286:12554-12564.
10. Gordon-Alonso M, Rocha-Perugini V, Alvarez S, Moreno-Gonzalo O, Ursa A, Lopez-Martin S, Izquierdo-Useros N, Martinez-Picado J, Munoz-Fernandez MA, Yanez-Mo M, Sanchez-Madrid F. The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry. Mol Biol Cell 2012, 23:2253-2263.
11. Pontow SE, Heyden NV, Wei S, Ratner L. Actin cytoskeletal reorganizations and coreceptor-mediated activation of rac during human immunodeficiency virus-induced cell fusion. J Virol 2004, 78:7138-7147.
12. Komano J, Miyauchi K, Matsuda Z, Yamamoto N. Inhibiting the Arp2/3 complex limits infection of both intracellular mature vaccinia virus and primate lentiviruses. Mol Biol Cell 2004, 15:5197-5207.
13. Harmon B, Campbell N, Ratner L. Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step. PLoS Pathog 2010, 6:e1000956.
14. dos Remedios CG, Chhabra D, Kekic M, Dedova IV, Tsubakihara M, Berry DA, Nosworthy NJ. Actin binding proteins: regulation of cytoskeletal microfilaments. Physiol Rev 2003, 83:433-473.
15. Kwiatkowski DJ, Stossel TP, Orkin SH, Mole JE, Colten HR, Yin HL. Plasma and cytoplasmic gelsolins are encoded by a single gene and contain a duplicated actin-binding domain. Nature 1986, 323:455-458.
16. Burtnick LD, Koepf EK, Grimes J, Jones EY, Stuart DI, McLaughlin PJ, Robinson RC. The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation. Cell 1997, 90:661-670.
17. Lu M, Witke W, Kwiatkowski DJ, Kosik KS. Delayed retraction of filopodia in gelsolin null mice. J Cell Biol 1997, 138:1279-1287.
18. Safiejko-Mroczka B, Bell PB. Reorganization of the actin cytoskeleton in the protruding lamellae of human fibroblasts. Cell Motil Cytoskeleton 2001, 50:13-32.
19. Mazur AJ, Gremm D, Dansranjavin T, Litwin M, Jockusch BM, Wegner A, Weeds AG, Mannherz HG. Modulation of actin filament dynamics by actin-binding proteins residing in lamellipodia. Eur J Cell Biol 2010, 89:402-413.
20. Selden LA, Kinosian HJ, Newman J, Lincoln B, Hurwitz C, Gershman LC, Estes JE. Severing of F-actin by the amino-terminal half of gelsolin suggests internal cooperativity in gelsolin. Biophys J 1998, 75:3092-3100.
21. Reichert A, Heintz D, Echner H, Voelter W, Faulstich H. The ternary complex of DNase I, actin and thymosin beta4. FEBS Lett 1996, 387:132-136.
22. Barrero-Villar M, Barroso-Gonzalez J, Cabrero JR, Gordon-Alonso M, Alvarez-Losada S, Munoz-Fernandez MA, Sanchez-Madrid F, Valenzuela-Fernandez A. PI4P5-kinase Ialpha is required for efficient HIV-1 entry and infection of T cells. J Immunol 2008, 181:6882-6888.
23. Barroso-Gonzalez J, El Jaber-Vazdekis N, Garcia-Exposito L, Machado JD, Zarate R, Ravelo AG, Estevez-Braun A, Valenzuela-Fernandez A. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. J Biol Chem 2009, 284:16609-16620.
24. Garcia-Exposito L, Barroso-Gonzalez J, Puigdomenech I, Machado JD, Blanco J, Valenzuela-Fernandez A. HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes. Mol Biol Cell 2011, 22:1148-1166.
25. Matlin KS, Reggio H, Helenius A, Simons K. Pathway of vesicular stomatitis virus entry leading to infection. J Mol Biol 1982, 156:609-631.
26. Campbell EM, Nunez R, Hope TJ. Disruption of the actin cytoskeleton can complement the ability of Nef to enhance human immunodeficiency virus type 1 infectivity. J Virol 2004, 78:5745-5755.
27. Qiao H, McMillan JR. Gelsolin segment 5 inhibits HIV-induced T-cell apoptosis via Vpr-binding to VDAC. FEBS Lett 2007, 581:535-540.
28. Cameron PU, Saleh S, Sallmann G, Solomon A, Wightman F, Evans VA, Boucher G, Haddad EK, Sekaly RP, Harman AN. Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton. Proc Natl Acad Sci USA 2010, 107:16934-16939.
29. Burtnick LD, Robinson RC, Choe S. Structure and function of gelsolin. Results Probl Cell Differ 2001, 32:201-211.
30. Yin HL, Albrecht JH, Fattoum A. Identification of gelsolin, a Ca2 + -dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues. J Cell Biol 1981, 91:901-906.
31. Azuma T, Witke W, Stossel TP, Hartwig JH, Kwiatkowski DJ. Gelsolin is a downstream effector of rac for fibroblast motility. EMBO J 1998, 17:1362-1370.
32. Chou J, Stolz DB, Burke NA, Watkins SC, Wells A. Distribution of gelsolin and phosphoinositol 4,5-bisphosphate in lamellipodia during EGF-induced motility. Int J Biochem Cell Biol 2002, 34:776-790.
33. Lindberg U, Schutt CE, Goldman RD, Nyakern-Meazza M, Hillberg L, Rathje LS, Grenklo S. Tropomyosins regulate the impact of actin binding proteins on actin filaments. Adv Exp Med Biol 2008, 644:223-231.
34. Crowley JL, Smith TC, Fang Z, Takizawa N, Luna EJ. Supervillin reorganizes the actin cytoskeleton and increases invadopodial efficiency. Mol Biol Cell 2009, 20:948-962.
35. Wang W, Guo J, Yu D, Vorster PJ, Chen W, Wu Y. A Dichotomy in Cortical Actin and Chemotactic Actin Activity between Human Memory and Naive T Cells Contributes to Their Differential Susceptibility to HIV-1 Infection. J Biol Chem 2012, 287:35455-35469.
36. Barroso-Gonzalez J, Garcia-Exposito L, Puigdomenech I, de Armas-Rillo L, Machado JD, Blanco J, Valenzuela-Fernandez A. Viral infection: moving through complex and dynamic cell-membrane structures. Commun Integr Biol 2011, 4:398-408.
37. Jones KL, Smyth RP, Pereira CF, Cameron PU, Lewin SR, Jaworowski A, Mak J. Early events of HIV-1 infection: can signaling be the next therapeutic target?. J Neuroimmune Pharmacol 2011, 6:269-283.
38. Dimitrov DS, Broder CC, Berger EA, Blumenthal R. Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction. J Virol 1993, 67:1647-1652.
39. Wonderlich ER, Leonard JA, Kulpa DA, Leopold KE, Norman JM, Collins KL. ADP Ribosylation Factor 1 Activity Is Required To Recruit AP-1 to the Major Histocompatibility Complex Class I (MHC-I) Cytoplasmic Tail and Disrupt MHC-I Trafficking in HIV-1-Infected Primary T Cells. J Virol 2011, 85:12216-12226.
40. Southwick FS. Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proc Natl Acad Sci USA 2000, 97:6936-6938.
41. Yin HL, Stossel TP. Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent regulatory protein. Nature 1979, 281:583-586.
42. Janmey PA, Stossel TP. Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate. Nature 1987, 325:362-364.
43. Kiselar JG, Janmey PA, Almo SC, Chance MR. Visualizing the Ca2 + -dependent activation of gelsolin by using synchrotron footprinting. Proc Natl Acad Sci USA 2003, 100:3942-3947.
44. Eitzen G. Actin remodeling to facilitate membrane fusion. Biochim Biophys Acta 2003, 1641:175-181.
45. Valenzuela-Fernandez A, Palanche T, Amara A, Magerus A, Altmeyer R, Delaunay T, Virelizier JL, Baleux F, Galzi JL, Arenzana-Seisdedos F. Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfate proteoglycans. J Biol Chem 2001, 276:26550-26558.
46. Valenzuela-Fernandez A, Planchenault T, Baleux F, Staropoli I, Le-Barillec K, Leduc D, Delaunay T, Lazarini F, Virelizier JL, Chignard M. Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem 2002, 277:15677-15689.
47. Valenzuela-Fernandez A, Alvarez S, Gordon-Alonso M, Barrero M, Ursa A, Cabrero JR, Fernandez G, Naranjo-Suarez S, Yanez-Mo M, Serrador JM. Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection. Mol Biol Cell 2005, 16:5445-5454.
48. Barroso-Gonzalez J, Machado JD, Garcia-Exposito L, Valenzuela-Fernandez A. Moesin regulates the trafficking of nascent clathrin-coated vesicles. J Biol Chem 2009, 284:2419-2434.
49. Gordon-Alonso M, Yanez-Mo M, Barreiro O, Alvarez S, Munoz-Fernandez MA, Valenzuela-Fernandez A, Sanchez-Madrid F. Tetraspanins CD9 and CD81 modulate HIV-1-induced membrane fusion. J Immunol 2006, 177:5129-5137.