Synthesis and inhibitory activities against colon cancer cell growth and proteasome of alkylresorcinols

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 35, 2012, Pages 8624-8631

  Zhu, Yingdong ^a   Soroka, Dominique N ^a   Sang, Shengmin ^a  

^a NORTH CAROLINA A AND T STATE UNIVERSITY   (United States)

Author keywords

5 alkylresorcinol analogues; colon cancer cells; growth inhibition; proteasome; synthesis

Indexed keywords

5-ALKYLRESORCINOL ANALOGUES; ACTIVE COMPONENTS; ANTI-TUMOR ACTIVITIES; AQUEOUS MEDIA; AROMATIC RINGS; COLON CANCER CELLS; GRIGNARD REACTION; GROWTH INHIBITION; HUMAN COLON CANCER CELLS; HYDROXYL GROUPS; INHIBITORY ACTIVITY; INHIBITORY EFFECT; PROTEASOMES; SIDE CHAIN LENGTHS; STRUCTURE ACTIVITY RELATIONSHIPS; WHEAT BRAN; WITTIG REACTION;

AROMATIC COMPOUNDS; BIOASSAY; CELLS; REACTION INTERMEDIATES;

SYNTHESIS (CHEMICAL);

ANTINEOPLASTIC AGENT; CHYMOTRYPSIN; PROTEASOME; PYROGALLOL; RESORCINOL DERIVATIVE; SERINE PROTEINASE INHIBITOR;

ALKYLATION; ARTICLE; CELL DIVISION; CELL STRAIN HCT116; CELL STRAIN HT29; CHEMISTRY; COLON TUMOR; DIETARY FIBER; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALKYLATION; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL DIVISION; CHYMOTRYPSIN; COLONIC NEOPLASMS; DIETARY FIBER; HCT116 CELLS; HT29 CELLS; HUMANS; PROTEASOME ENDOPEPTIDASE COMPLEX; PYROGALLOL; RESORCINOLS; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

TRITICUM AESTIVUM;

EID: 84865858688     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf302872a     Document Type: Article

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