메뉴 건너뛰기




Volumn 64, Issue 1, 2012, Pages 44-54

A short history of anti-rheumatic therapy VIII. The immunosuppressants

Author keywords

Azathioprine; Cyclophosphamide; Cyclosporin A; History of rheumatology; Immunosuppressive drugs; Methotrexate; Mycophenolate mofetil; Thalidomide

Indexed keywords

ALLOPURINOL; AMINOPTERIN; ANTIRHEUMATIC AGENT; AZATHIOPRINE; CHLORAMBUCIL; CYCLOPHOSPHAMIDE; CYCLOSPORIN; DAPSONE; FOLIC ACID; IMIDAZOLE; IMMUNOSUPPRESSIVE AGENT; LEFLUNOMIDE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SMALLPOX VACCINE; THALIDOMIDE; ALKYLATING AGENT; ANTIMETABOLITE; FOLIC ACID ANTAGONIST; MYCOPHENOLIC ACID;

EID: 84875910818     PISSN: 00487449     EISSN: None     Source Type: Journal    
DOI: 10.4081/reumatismo.2012.44     Document Type: Article
Times cited : (3)

References (97)
  • 1
    • 84875878265 scopus 로고
    • Der Rheumatismus: Patologischeanatomische und experimentellpatologische Tatsachen und ihre Auswertung für das ärztliche Rheumaproblem
    • Klinge F. Der Rheumatismus: patologischeanatomische und experimentellpatologische Tatsachen und ihre Auswertung für das ärztliche Rheumaproblem. Ergebn Allg Path path Anat. 1933; 27: 1-336.
    • (1933) Ergebn Allg Path path Anat , vol.27 , pp. 1-336
    • Klinge, F.1
  • 2
    • 84979107869 scopus 로고
    • On the occurrence of a factor in human serum activating the specific agglutination of sheep blood corpuscles
    • Waaler E. On the occurrence of a factor in human serum activating the specific agglutination of sheep blood corpuscles. Acta Pathol Microbiol Scand. 1940; 17: 172-88.
    • (1940) Acta Pathol Microbiol Scand , vol.17 , pp. 172-188
    • Waaler, E.1
  • 3
    • 84925021146 scopus 로고
    • Differential agglutination of normal and sensitized sheep erythrocytes by sera of patients with rheumatoid arthritis
    • Rose HM, Ragan C, Pearce C, Lipman MO. Differential agglutination of normal and sensitized sheep erythrocytes by sera of patients with rheumatoid arthritis. Proc Soc Exp Biol Med. 1948; 68:1-6.
    • (1948) Proc Soc Exp Biol Med. , vol.68 , pp. 1-6
    • Rose, H.M.1    Ragan, C.2    Pearce, C.3    Lipman, M.O.4
  • 4
  • 5
    • 33846816853 scopus 로고    scopus 로고
    • Edward Jenner and the history of smallpox and vaccination
    • Riedel S. Edward Jenner and the history of smallpox and vaccination. Proc Bayl Univ Med Cent. 2005; 18: 21-5.
    • (2005) Proc Bayl Univ Med Cent , vol.18 , pp. 21-25
    • Riedel, S.1
  • 7
    • 0009971838 scopus 로고
    • Nitrogen mustard therapy in cutaneous blastomatous disease
    • Osborne ED, Jordan JW, Hoak FC, Pschierer FJ. Nitrogen mustard therapy in cutaneous blastomatous disease. JAMA. 1947; 135: 1123-8.
    • (1947) JAMA , vol.135 , pp. 1123-1128
    • Osborne, E.D.1    Jordan, J.W.2    Hoak, F.C.3    Pschierer, F.J.4
  • 8
    • 76549239323 scopus 로고
    • Therapeutic suppression of tissue reactivity. II. Effect of aminopterin in rheumatoid arthritis and psoriasis
    • Gubner R, August S, Ginsburg V. Therapeutic suppression of tissue reactivity. II. Effect of aminopterin in rheumatoid arthritis and psoriasis. Am J Med Sci. 1951; 221: 176-82.
    • (1951) Am J Med Sci , vol.221 , pp. 176-182
    • Gubner, R.1    August, S.2    Ginsburg, V.3
  • 9
    • 0345577486 scopus 로고
    • Treatment of dysreaction diseases with nitrogen mustards
    • Jimenez-Diaz C. Treatment of dysreaction diseases with nitrogen mustards. Ann Rheum Dis. 1951; 10: 144-52.
    • (1951) Ann Rheum Dis , vol.10 , pp. 144-152
    • Jimenez-Diaz, C.1
  • 11
    • 18844469830 scopus 로고
    • Guidelines for the use of cytotoxic drugs in rheumatic diseases
    • Schwartz RS, Gowans JD. Guidelines for the use of cytotoxic drugs in rheumatic diseases. Arthritis Rheum. 1971; 14: 134-7.
    • (1971) Arthritis Rheum , vol.14 , pp. 134-137
    • Schwartz, R.S.1    Gowans, J.D.2
  • 12
    • 0036338754 scopus 로고    scopus 로고
    • The schizofrenic career of a "monster drug"
    • Silverman WA. The schizofrenic career of a "monster drug". Pediatrics 2002; 110: 404-6.
    • (2002) Pediatrics , vol.110 , pp. 404-406
    • Silverman, W.A.1
  • 13
    • 79960568661 scopus 로고    scopus 로고
    • Piccola storia della terapia antireumatica-VI. I farmaci dell'artrite reumatoide
    • Pasero G, Marson P. Piccola storia della terapia antireumatica-VI. I farmaci dell'artrite reumatoide. Reumatismo. 2011; 63: 111-23.
    • (2011) Reumatismo , vol.63 , pp. 111-123
    • Pasero, G.1    Marson, P.2
  • 14
    • 0020962068 scopus 로고
    • Clinical pharmacology and toxicology of cyclophosphamide. Emphasis on use in rheumatic diseases
    • Kovarsky J. Clinical pharmacology and toxicology of cyclophosphamide. Emphasis on use in rheumatic diseases. Semin Arthritis Rheum. 1983; 12: 359-68.
    • (1983) Semin Arthritis Rheum , vol.12 , pp. 359-368
    • Kovarsky, J.1
  • 15
    • 79955545949 scopus 로고
    • Dizionario di chimica generale e industriale
    • Giua M, Giua-Lollini C. Dizionario di chimica generale e industriale. Torino, UTET. 1948; 1: 326.
    • (1948) Torino, UTET , vol.1 , pp. 326
    • Giua, M.1    Giua-Lollini, C.2
  • 16
    • 0001412401 scopus 로고
    • The blood and the bone marrow in yellow cross gas (mustard gas) poisoning: Changes produced in the bone marrow of fatal cases
    • Krumbhaar EB, Krumbhaar HD. The blood and the bone marrow in yellow cross gas (mustard gas) poisoning: changes produced in the bone marrow of fatal cases. J Med Res. 1919; 40: 497-508.
    • (1919) J Med Res , vol.40 , pp. 497-508
    • Krumbhaar, E.B.1    Krumbhaar, H.D.2
  • 17
    • 0001501849 scopus 로고
    • The modifying influence of dichloroethyl sulphide on the induction of tumours in mice by tar
    • Berenblum I. The modifying influence of dichloroethyl sulphide on the induction of tumours in mice by tar. J Pathol Bacteriol. 1929; 32: 425-34.
    • (1929) J Pathol Bacteriol , vol.32 , pp. 425-434
    • Berenblum, I.1
  • 18
    • 0035720354 scopus 로고    scopus 로고
    • Origins of cancer therapy
    • Papac RJ. Origins of cancer therapy. Yale J Biol Med. 2001; 74: 391-8.
    • (2001) Yale J Biol Med , vol.74 , pp. 391-398
    • Papac, R.J.1
  • 19
    • 0000636701 scopus 로고
    • The initial clinical trial of nitrogen mustard
    • Gilman A. The initial clinical trial of nitrogen mustard. Am J Surg. 1963; 105: 574-8.
    • (1963) Am J Surg , vol.105 , pp. 574-578
    • Gilman, A.1
  • 21
    • 14744269420 scopus 로고
    • Nitrogen mustard therapy
    • use of methyl-bis(betachloroethyl(amine hydrochloride and tris(betachloroethylamine hydrochloride in the treatment of Hodgkin's disease, lymphosarcoma, leukemia, and certain allied and miscellaneous disorders (riprodotto anche in JAMA. 1984; 251: 2255-61)
    • Goodman LS, Wintrobe MM, Dameshek W, Goodman MJ, Gilman A, McLennan. Nitrogen mustard therapy. Use of methyl-bis(betachloroethyl(amine hydrochloride and tris(betachloroethylamine hydrochloride in the treatment of Hodgkin's disease, lymphosarcoma, leukemia, and certain allied and miscellaneous disorders. JAMA. 1946; 105: 475-6 (riprodotto anche in JAMA. 1984; 251: 2255-61).
    • (1946) JAMA , vol.105 , pp. 475-476
    • Goodman, L.S.1    Wintrobe, M.M.2    Dameshek, W.3    Goodman, M.J.4    McLennan, G.A.5
  • 22
    • 0030213253 scopus 로고    scopus 로고
    • The history of oxazaphosphorine cytostatics
    • Brock N. The history of oxazaphosphorine cytostatics. Cancer. 1996; 78: 542-7.
    • (1996) Cancer , vol.78 , pp. 542-547
    • Brock, N.1
  • 23
    • 0000957859 scopus 로고
    • Chemotherapeutic action of a cyclic nitrogen mustard phosphamide ester (B 518 ASTA)
    • Arnold H, Bourseaux F, Brock N. Chemotherapeutic action of a cyclic nitrogen mustard phosphamide ester (B 518 ASTA). Nature. 1958; 181: 931.
    • (1958) Nature , vol.181 , pp. 931
    • Arnold, H.1    Bourseaux, F.2    Brock, N.3
  • 24
    • 84965059977 scopus 로고
    • Die Beinflussding der Antikörper-Bildung durch Zytostatika und Röntgenbestrahlung
    • Stender HS, Ringleb D, Strauch D, Winter H. Die Beinflussding der Antikörper-Bildung durch Zytostatika und Röntgenbestrahlung. Strahlentherapie. 1959; (Suppl. 43): 392-9.
    • (1959) Strahlentherapie , Issue.SUPPL. 43 , pp. 392-399
    • Stender, H.S.1    Ringleb, D.2    Strauch, D.3    Winter, H.4
  • 25
    • 0014274816 scopus 로고
    • Long-term cyclophosphamide therapy in rheumatoid arthritis
    • Fosdick WM, Parsons JL, Hill DF. Long-term cyclophosphamide therapy in rheumatoid arthritis. Arthritis Rheum. 1968; 11: 151-61.
    • (1968) Arthritis Rheum , vol.11 , pp. 151-161
    • Fosdick, W.M.1    Parsons, J.L.2    Hill, D.F.3
  • 26
    • 84982056793 scopus 로고
    • Treatment of discoid and subacute lupus erythematosus with cyclophosphamide
    • Schultz EJ, Menter MA. Treatment of discoid and subacute lupus erythematosus with cyclophosphamide. Br J Dermatol. 1971; (Suppl. 7): 60-5.
    • (1971) Br J Dermatol. , Issue.SUPPL. 7 , pp. 60-65
    • Schultz, E.J.1    Menter, M.A.2
  • 27
    • 0015764397 scopus 로고
    • Wegener's granulomatosis
    • Studies in eighteen patients and review of the literature, (riprodotto anche in Medicine. 1994; 73: 315-24)
    • Fauci AS, Wolff SM. Wegener's granulomatosis. Studies in eighteen patients and review of the literature. Medicine (Baltimore) 1973; 52: 535-61 (riprodotto anche in Medicine. 1994; 73: 315-24).
    • (1973) Medicine (Baltimore) , vol.52 , pp. 535-561
    • Fauci, A.S.1    Wolff, S.M.2
  • 29
    • 0018121571 scopus 로고
    • Effect of pulse dose cyclophosphamide on the anamnestic immune response in NZB/W mice
    • Levy L, Chia D, Barnett EV. Effect of pulse dose cyclophosphamide on the anamnestic immune response in NZB/W mice. Agent Actions. 1978; 8: 644-51.
    • (1978) Agent Actions , vol.8 , pp. 644-651
    • Levy, L.1    Chia, D.2    Barnett, E.V.3
  • 31
    • 84965244622 scopus 로고
    • Treatment of 'pernicious anaemia of pregnancy' and 'tropical anemia', with special reference to yeast extract as a curative agent
    • Wills L. Treatment of 'pernicious anaemia of pregnancy' and 'tropical anemia', with special reference to yeast extract as a curative agent. Br Med J. 1931; i: 1059-64.
    • (1931) Br Med J. , vol.1 , pp. 059-1064
    • Wills, L.1
  • 32
  • 33
    • 0001135467 scopus 로고
    • The concentration of 'folic acid'
    • (riprodotto anche in Nutr Rev. 1988; 46: 324-5)
    • Mitchell HK, Snell EE, Williams RJ. The concentration of 'folic acid'. J Am Chem Soc. 1941; 63: 2284-7 (riprodotto anche in Nutr Rev. 1988; 46: 324-5).
    • (1941) J Am Chem Soc. , vol.63 , pp. 2284-2287
    • Mitchell, H.K.1    Snell, E.E.2    Williams, R.J.3
  • 34
    • 0004902960 scopus 로고
    • Anaemia in chicks caused by a vitamin deficiency
    • Hogan AG, Parrot EM. Anaemia in chicks caused by a vitamin deficiency. J Biol Chem. 1940; 132: 507-17.
    • (1940) J Biol Chem , vol.132 , pp. 507-517
    • Hogan, A.G.1    Parrot, E.M.2
  • 35
    • 0004891108 scopus 로고
    • Growth factors for bacteria. X. Additional factors required by certain lactic acid bacteria
    • Snell EE, Peterson WH. Growth factors for bacteria. X. Additional factors required by certain lactic acid bacteria. J Bacteriol. 1940; 39: 273-85.
    • (1940) J Bacteriol , vol.39 , pp. 273-285
    • Snell, E.E.1    Peterson, W.H.2
  • 36
  • 38
    • 0004883678 scopus 로고
    • Further studies on folic acid in the treatment of macrocytic anemia
    • Spies TD, Vilter CF, Koch MB, Caldwell MH. Further studies on folic acid in the treatment of macrocytic anemia. South Med J. 1945; 38: 781-5.
    • (1945) South Med J , vol.38 , pp. 781-785
    • Spies, T.D.1    Vilter, C.F.2    Koch, M.B.3    Caldwell, M.H.4
  • 41
    • 78651010566 scopus 로고
    • Temporary remission in acute leukemia in children produced by folic antagonist 4-amethopteroylglutamic acid (aminopterin)
    • Farber S, Diamond LK, Mercer RD, Sylvester RF, Wolff JA. Temporary remission in acute leukemia in children produced by folic antagonist 4-amethopteroylglutamic acid (aminopterin). N Engl J Med. 1948; 238: 787-93.
    • (1948) N Engl J Med , vol.238 , pp. 787-793
    • Farber, S.1    Diamond, L.K.2    Mercer, R.D.3    Sylvester, R.F.4    Wolff, J.A.5
  • 42
    • 84875900604 scopus 로고
    • Comparative effects of aminopterin, cortisone and ACTH in experimental formaldehyde arthritis and psoriatic arthritis
    • Gubner R, Cote L, Hughes J, Oleson JJ, Ruegsegger JM, Williams JH. Comparative effects of aminopterin, cortisone and ACTH in experimental formaldehyde arthritis and psoriatic arthritis. J Invest Dermatol. 1952; 19: 297-305.
    • (1952) J Invest Dermatol , vol.19 , pp. 297-305
    • Gubner, R.1    Cote, L.2    Hughes, J.3    Oleson, J.J.4    Ruegsegger, J.M.5    Williams, J.H.6
  • 43
    • 0014233443 scopus 로고
    • Amethopterin (methotrexate) in connective tissue disease-psoriasis and polyarthritis
    • Kersley GD. Amethopterin (methotrexate) in connective tissue disease-psoriasis and polyarthritis. Ann Rheum Dis. 1968; 27: 64-6.
    • (1968) Ann Rheum Dis , vol.27 , pp. 64-66
    • Kersley, G.D.1
  • 45
    • 11144234188 scopus 로고
    • Therapy of choriocarcinoma and related trophoblastic tumors with folic acid and purine antagonists
    • Li MC, Hertz R, Bergenstal DM. Therapy of choriocarcinoma and related trophoblastic tumors with folic acid and purine antagonists. N Engl J Med 1958, 259: 66-74.
    • (1958) N Engl J Med , vol.259 , pp. 66-74
    • Li, M.C.1    Hertz, R.2    Bergenstal, D.M.3
  • 46
    • 0342963005 scopus 로고
    • Clinical trial of amethopterin (methotrexate) in psoriatic and rheumatoid arthritis (preliminary report)
    • (Abstr)
    • O'Brien WM, Van Scott EJ, Black RL, Eisen AZ, Bunim JJ. Clinical trial of amethopterin (methotrexate) in psoriatic and rheumatoid arthritis (preliminary report). Arthritis Rheum. 1962; 5: 312 (Abstr).
    • (1962) Arthritis Rheum , vol.5 , pp. 312
    • O'Brien, W.M.1    van Scott, E.J.2    Black, R.L.3    Eisen, A.Z.4    Bunim, J.J.5
  • 47
    • 0000685404 scopus 로고
    • Methotrexate in rheumatoid arthritis
    • (Abstr)
    • Hoffmeister RT. Methotrexate in rheumatoid arthritis. Arthritis Rheum. 1972; 15: 114 (Abstr).
    • (1972) Arthritis Rheum , vol.15 , pp. 114
    • Hoffmeister, R.T.1
  • 49
    • 78650540723 scopus 로고    scopus 로고
    • Methotrexate: From its introduction to non-oncologic therapeutics to anti-TNF-T
    • Benedek TG. Methotrexate: from its introduction to non-oncologic therapeutics to anti-TNF-T. Clin Exp Rheumatol. 2010; 28 (Suppl 61): S3-8.
    • (2010) Clin Exp Rheumatol. , vol.28 , Issue.SUPPL. 61
    • Benedek, T.G.1
  • 50
    • 0015337190 scopus 로고
    • Therapy of rheumatoid arthritis: A pyramidal plan
    • Smythe CJ. Therapy of rheumatoid arthritis: a pyramidal plan. Postgrad Med. 1972; 51: 31-9.
    • (1972) Postgrad Med , vol.51 , pp. 31-39
    • Smythe, C.J.1
  • 51
    • 0024673211 scopus 로고
    • Remodeling the pyramid-a concept whose time has come
    • Wilske KR, Healey LA. Remodeling the pyramid-a concept whose time has come. J Rheumatol. 1989; 16: 565-7.
    • (1989) J Rheumatol , vol.16 , pp. 565-567
    • Wilske, K.R.1    Healey, L.A.2
  • 53
    • 0024554561 scopus 로고
    • The purine path to chemotherapy
    • Elion GB. The purine path to chemotherapy. Science. 1989; 244: 41-7.
    • (1989) Science , vol.244 , pp. 41-47
    • Elion, G.B.1
  • 54
    • 76549217546 scopus 로고
    • Preliminary studies on the clinical toxicity of 5-amino-7hydroxy-1-vtriazolo(d)pyrimidine (guanazolo)
    • Armistead GC Jr, Burchenal JH, Karnofsky D, Southam CM. Preliminary studies on the clinical toxicity of 5-amino-7hydroxy-1-vtriazolo(d)pyrimidine (guanazolo). Cancer N.Y. 1949; 2: 1087-8.
    • (1949) Cancer N. Y , vol.2 , pp. 1087-1088
    • Armistead Jr., G.C.1    Burchenal, J.H.2    Karnofsky, D.3    Southam, C.M.4
  • 56
    • 0000345568 scopus 로고
    • Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines
    • Elion GB, Burgi E, Hitchings GH. Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines. J Am Chem Ass. 1952; 74: 411-4.
    • (1952) J Am Chem Ass , vol.74 , pp. 411-414
    • Elion, G.B.1    Burgi, E.2    Hitchings, G.H.3
  • 57
    • 0000993057 scopus 로고
    • Treatment of certain "autoimmune" diseases with antimetabolites: A preliminary report
    • Damashek W, Schwartz R. Treatment of certain "autoimmune" diseases with antimetabolites: a preliminary report. Trans Assoc Am Physicians. 1960; 73: 113-27.
    • (1960) Trans Assoc Am Physicians , vol.73 , pp. 113-127
    • Damashek, W.1    Schwartz, R.2
  • 58
    • 0015501552 scopus 로고
    • Immunosuppressive therapy
    • Skinner MD, Schwartz RS. Immunosuppressive therapy. 1. N Engl J Med. 1972; 287: 221-7.
    • (1972) N Engl J Med , vol.287 , Issue.1 , pp. 221-227
    • Skinner, M.D.1    Schwartz, R.S.2
  • 60
    • 0344353552 scopus 로고
    • Chemical suppression of the immune response
    • Hitchings GH, Elion GB. Chemical suppression of the immune response. Pharmacol Rev. 1963; 15: 365-405.
    • (1963) Pharmacol Rev , vol.15 , pp. 365-405
    • Hitchings, G.H.1    Elion, G.B.2
  • 61
    • 50449120039 scopus 로고
    • Daraprim as an antagonist of folic and folinic acids
    • Hitchings GH. Daraprim as an antagonist of folic and folinic acids. Trans R Soc Trop Med Hyg. 1952; 46: 467-73.
    • (1952) Trans R Soc Trop Med Hyg , vol.46 , pp. 467-473
    • Hitchings, G.H.1
  • 62
    • 33947476062 scopus 로고
    • 5-benzyl-2,4-diaminopirymidines as antibacterial agents. I. Synthesis and antibacterial activity in vitro
    • Roth B, Falco EA, Hitchings GH, Bushby SR. 5-benzyl-2,4-diaminopirymidines as antibacterial agents. I. Synthesis and antibacterial activity in vitro. J Med Pharm Chem. 1962; 91: 1103-23.
    • (1962) J Med Pharm Chem , vol.91 , pp. 1103-1123
    • Roth, B.1    Falco, E.A.2    Hitchings, G.H.3    Bushby, S.R.4
  • 64
    • 0001707601 scopus 로고
    • 3′-azido-3′deoxythymidine (BW A509U): An antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
    • Mitsuya H, Weinhold KJ, Furman PA, StClair MH, Lehrman SN, Gallo RC, Bolognesi D, Barry DW, Broder S. 3′-azido-3′deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro. Proc Natl Acad Sci USA 1985; 82: 7096-100.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 7096-7100
    • Mitsuya, H.1    Weinhold, K.J.2    Furman, P.A.3    StClair, M.H.4    Lehrman, S.N.5    Gallo, R.C.6    Bolognesi, D.7    Barry, D.W.8    Broder, S.9
  • 65
    • 0021808688 scopus 로고
    • The development of allopurinol
    • Rundles RW. The development of allopurinol. Arch Intern Med. 1985; 145: 1492-503.
    • (1985) Arch Intern Med , vol.145 , pp. 1492-1503
    • Rundles, R.W.1
  • 66
    • 0034681683 scopus 로고    scopus 로고
    • The Nobel chronicles 1988: James Whyte Black (b 1924), Gertrude Elion (1918-99) and George H Hitchings (1905-98)
    • Raju TN. The Nobel chronicles. 1988: James Whyte Black (b 1924), Gertrude Elion (1918-99) and George H. Hitchings (1905-98). Lancet. 2000; 355: 1022.
    • (2000) Lancet , vol.355 , pp. 1022
    • Raju, T.N.1
  • 67
    • 76949110861 scopus 로고
    • Bifunctional sulphonic acid esters with radiomimetic activity
    • Haddow A, Timmis GM. Bifunctional sulphonic acid esters with radiomimetic activity. Acta Unio Int Contra Cancrum. 1951; 7: 469-71.
    • (1951) Acta Unio Int Contra Cancrum , vol.7 , pp. 469-471
    • Haddow, A.1    Timmis, G.M.2
  • 68
    • 84873363702 scopus 로고
    • On influence of stilbamidine upon multiple myeloma
    • Snapper I. On influence of stilbamidine upon multiple myeloma. J Mt Sinai Hosp. 1946; 13: 119-27.
    • (1946) J Mt Sinai Hosp , vol.13 , pp. 119-127
    • Snapper, I.1
  • 69
    • 0025828581 scopus 로고
    • The discovery and development of cyclosporine (Sandimmun®)
    • Borel JF, Kis ZL. The discovery and development of cyclosporine (Sandimmun®). Transplant Proc. 1991; 23: 1867-74
    • (1991) Transplant Proc , vol.23 , pp. 1867-1874
    • Borel, J.F.1    Kis, Z.L.2
  • 70
    • 0029671145 scopus 로고    scopus 로고
    • The history of cyclosporine (Sandimmun®) revisited: Another point of view
    • Stähelin HF. The history of cyclosporine (Sandimmun®) revisited: another point of view. Experientia. 1996; 52: 5-13.
    • (1996) Experientia , vol.52 , pp. 5-13
    • Stähelin, H.F.1
  • 71
    • 0035795893 scopus 로고    scopus 로고
    • The controversial early history of cyclosporin
    • Heusler K, Pletscher A. The controversial early history of cyclosporin. Swiss Med Wkly. 2001; 131: 299-302.
    • (2001) Swiss Med Wkly , vol.131 , pp. 299-302
    • Heusler, K.1    Pletscher, A.2
  • 72
    • 0035795893 scopus 로고    scopus 로고
    • The controversial early history of cyclosporine
    • Heusler K Pletscher A. The controversial early history of cyclosporine. Swiss Med Wkly. 2001; 131: 299-302.
    • (2001) Swiss Med Wkly , vol.131 , pp. 299-302
    • Heusler, K.1    Pletscher, A.2
  • 73
    • 0017157814 scopus 로고
    • Biological effects of cyclosporin A: A new anti-lymphocytic agent
    • (riprodotto anche in Agent Actions 1994; 43: 179-86)
    • Borel JF, Feurer C, Gubler HU, Stähelin HF. Biological effects of cyclosporin A: a new anti-lymphocytic agent. Agents Actions. 1976; 6: 468-75 (riprodotto anche in Agent Actions 1994; 43: 179-86).
    • (1976) Agents Actions , vol.6 , pp. 468-475
    • Borel, J.F.1    Feurer, C.2    Gubler, H.U.3    Stähelin, H.F.4
  • 75
    • 0002171117 scopus 로고
    • Combined cyclosporin-steroid treatment of systemic lupus erythematosus
    • In: (Schindler R, ed). Berlin, Springer
    • Miescher PA, Miescher A. Combined cyclosporin-steroid treatment of systemic lupus erythematosus. In: Cyclosporin in autoimmune diseases (Schindler R, ed). Berlin, Springer, 1985: 337-45.
    • (1985) Cyclosporin in autoimmune diseases , pp. 337-345
    • Miescher, P.A.1    Miescher, A.2
  • 76
    • 0023137311 scopus 로고
    • An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: A preliminary report
    • Førre O, Bjerkhoel F, Salvesen CF, Berg KJ, Rugstad HE, Saelid G, Mellbye OJ, Kåss E. An open, controlled, randomized comparison of cyclosporine and azathioprine in the treatment of rheumatoid arthritis: a preliminary report. Arthritis Rheum. 1987; 30: 88-92.
    • (1987) Arthritis Rheum , vol.30 , pp. 88-92
    • Førre, O.1    Bjerkhoel, F.2    Salvesen, C.F.3    Berg, K.J.4    Rugstad, H.E.5    Saelid, G.6    Mellbye, O.J.7    Kåss, E.8
  • 77
    • 0024565498 scopus 로고
    • Double-masked trial of cyclosporin versus colchicine and longterm open study of cyclosporin in Behçet's disease
    • Masuda K, Nakajima A, Urayama A, Nakae K, Kogure M, Inaba G. Double-masked trial of cyclosporin versus colchicine and longterm open study of cyclosporin in Behçet's disease. Lancet. 1989; i: 1093-6.
    • (1989) Lancet. , vol.1 , pp. 093-1096
    • Masuda, K.1    Nakajima, A.2    Urayama, A.3    Nakae, K.4    Kogure, M.5    Inaba, G.6
  • 78
    • 0018321051 scopus 로고
    • Cyclosporin A for psoriasis
    • Mueller W, Herrmann B. Cyclosporin A for psoriasis. N Engl J Med. 1979; 301: 555.
    • (1979) N Engl J Med , vol.301 , pp. 555
    • Mueller, W.1    Herrmann, B.2
  • 79
    • 0000395398 scopus 로고
    • Ricerche batteriologiche e cliniche sulle alterazioni del mais
    • Citato da: Bentley R. Bartolomeo Gosio, 1863-1944: an appreciation. Adv Appl Microbiol. 2001; 48: 229-50
    • Gosio B. Ricerche batteriologiche e cliniche sulle alterazioni del mais. Riv Igiene Sanità Pubblica 1896; 7: 825-68. Citato da: Bentley R. Bartolomeo Gosio, 1863-1944: an appreciation. Adv Appl Microbiol. 2001; 48: 229-50.
    • (1896) Riv Igiene Sanità Pubblica , vol.7 , pp. 825-868
    • Gosio, B.1
  • 80
    • 0014546166 scopus 로고
    • The inhibition of nucleic acid synthesis by mycophenolic acid
    • Franklin TJ, Cook JM. The inhibition of nucleic acid synthesis by mycophenolic acid. Biochem J. 1969; 113: 515-24.
    • (1969) Biochem J , vol.113 , pp. 515-524
    • Franklin, T.J.1    Cook, J.M.2
  • 82
    • 0025087579 scopus 로고
    • Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T-and Bcell purine synthesis
    • Morris RE, Hoyt EG, Murphy MP, Eugui EM, Allison AC. Mycophenolic acid morpholinoethylester (RS-61443) is a new immunosuppressant that prevents and halts heart allograft rejection by selective inhibition of T-and Bcell purine synthesis. Transplant Proc. 1990; 22: 1659-62.
    • (1990) Transplant Proc , vol.22 , pp. 1659-1662
    • Morris, R.E.1    Hoyt, E.G.2    Murphy, M.P.3    Eugui, E.M.4    Allison, A.C.5
  • 83
    • 0030590745 scopus 로고    scopus 로고
    • Mycophenolate mofetil
    • Lipsky JJ. Mycophenolate mofetil. Lancet. 1996; 348: 1357-9.
    • (1996) Lancet , vol.348 , pp. 1357-1359
    • Lipsky, J.J.1
  • 84
    • 0034045586 scopus 로고    scopus 로고
    • Mycophenolate mofetil and its mechanisms of action
    • Allison AC, Eugui EM. Mycophenolate mofetil and its mechanisms of action. Immunopharmacology. 2000; 46: 85-118.
    • (2000) Immunopharmacology , vol.46 , pp. 85-118
    • Allison, A.C.1    Eugui, E.M.2
  • 85
    • 0022569531 scopus 로고
    • Domagk and the development of the sulphonamides
    • Otten H. Domagk and the development of the sulphonamides. J Antimicrob Chemother. 1986; 17: 689-90.
    • (1986) J Antimicrob Chemother , vol.17 , pp. 689-690
    • Otten, H.1
  • 87
    • 0019984271 scopus 로고
    • Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy
    • Hall RP, Lawley TJ, Smith HR, Katz SI. Bullous eruption of systemic lupus erythematosus. Dramatic response to dapsone therapy. Ann Intern Med. 1982; 97: 165-70.
    • (1982) Ann Intern Med , vol.97 , pp. 165-170
    • Hall, R.P.1    Lawley, T.J.2    Smith, H.R.3    Katz, S.I.4
  • 89
    • 47349113508 scopus 로고
    • Thalidomide and congenital abnormalities
    • McBride WG. Thalidomide and congenital abnormalities. Lancet. 1961; ii: 1358.
    • (1961) Lancet. , vol.2 , pp. 1358
    • McBride, W.G.1
  • 90
    • 0000962444 scopus 로고
    • Kindliche Missbildungen nach Medikament-Einnahme während der Gravidat
    • Lenz W. Kindliche Missbildungen nach Medikament-Einnahme während der Gravidat. Dtsch Med Wschr. 1961; 86: 2555-6.
    • (1961) Dtsch Med Wschr , vol.86 , pp. 2555-2556
    • Lenz, W.1
  • 91
    • 0013996778 scopus 로고
    • Therapie der Lepra-Reaktion mit Thalidomid (Eine Doppel-blind-Studie). Vorläufige Mitteilung
    • Sheskin J. Therapie der Lepra-Reaktion mit Thalidomid (Eine Doppel-blind-Studie). Vorläufige Mitteilung. Hautarzt. 1966; 17: 548-9.
    • (1966) Hautarzt , vol.17 , pp. 548-549
    • Sheskin, J.1
  • 92
    • 0027230553 scopus 로고
    • Thalidomide exerts ist inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation
    • Moreira AL, Sampaio EP, Zmuidzinas A, Frindt P, Smith KA, Kaplan G. Thalidomide exerts ist inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation. J Exp Med. 1993; 177: 1675-80.
    • (1993) J Exp Med , vol.177 , pp. 1675-1680
    • Moreira, A.L.1    Sampaio, E.P.2    Zmuidzinas, A.3    Frindt, P.4    Smith, K.A.5    Kaplan, G.6
  • 94
    • 0021163612 scopus 로고
    • Thalidomide. A promising new treatment for rheumatoid arthritis
    • Gutiérrez-Rodríguez O. Thalidomide. A promising new treatment for rheumatoid arthritis. Arthritis Rheum. 1984; 27: 1118-21.
    • (1984) Arthritis Rheum , vol.27 , pp. 1118-1121
    • Gutiérrez-Rodríguez, O.1
  • 96
    • 0032520803 scopus 로고    scopus 로고
    • Thalidomide in the treatment of mucocutaneous lesions of the Behçet's syndrome. A randomized, double-blind, placebo-controlled trial
    • Hamuryudan V, Mat C, Saip S, Ozyazgan Y, Siva A, Yurdakul S, Zwingenberger K, Yazici H. Thalidomide in the treatment of mucocutaneous lesions of the Behçet's syndrome. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998; 128: 443-50.
    • (1998) Ann Intern Med , vol.128 , pp. 443-450
    • Hamuryudan, V.1    Mat, C.2    Saip, S.3    Ozyazgan, Y.4    Siva, A.5    Yurdakul, S.6    Zwingenberger, K.7    Yazici, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.