A comparison of 4β-hydroxycholesterol: Cholesterol and 6β-hydroxycortisol: Cortisol as markers of CYP3A4 induction

British Journal of Clinical Pharmacology

Volumn 75, Issue 6, 2013, Pages 1536-1540

  Mårde Arrhén, Yvonne ^a   Nylén, Hanna ^b   Lövgren Sandblom, Anita ^b   Kanebratt, Kajsa P ^c   Wide, Katarina ^b   Diczfalusy, Ulf ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

CYP3A4; Endogenous markers; Induction; LC MS MS; Rifampicin

Indexed keywords

4BETA HYDROXYCHOLESTEROL; 6BETA HYDROXYHYDROCORTISONE; CHOLESTEROL; CHOLESTEROL DERIVATIVE; CYTOCHROME P450 3A4; HYDROCORTISONE; RIFAMPICIN; UNCLASSIFIED DRUG;

ARTICLE; BLOOD CHEMISTRY; BLOOD SAMPLING; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; MALE; MASS FRAGMENTOGRAPHY; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; TANDEM MASS SPECTROMETRY; URINALYSIS;

ANTIBIOTICS, ANTITUBERCULAR; BIOLOGICAL MARKERS; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP3A; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROCORTISONE; HYDROXYCHOLESTEROLS; MALE; RIFAMPIN;

EID: 84875825678     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/bcp.12016     Document Type: Article

References (7)

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