Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques

Chemico-Biological Interactions

Volumn 203, Issue 1, 2013, Pages 167-171

  Rosenberg, Yvonne J ^a   Laube, Beth ^b   Mao, Lingjun ^a   Jiang, Xiaoming ^a   Hernandez Abanto, Segundo ^a   Lee, Keunmyoung D ^c   Adams, Robert ^b  

^a PlantVax Corporation   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Human Biostar   (United States)

Author keywords

Aerosol delivery; Butyrylcholinesterase; Monkey model; Paraoxon; Protection

Indexed keywords

CHOLINESTERASE; MACROGOL; PARAOXON; RECOMBINANT BUTYRYLCHOLINESTERASE; UNCLASSIFIED DRUG;

AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CHO CELL; CHOLINERGIC SYNAPSE; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG RETENTION; DRUG STABILITY; ENZYME ACTIVITY; ERYTHROCYTE; GAMMA SCINTIGRAPHY; LUNG; MACACA; NONHUMAN; ORGANOPHOSPHATE POISONING; PROTEIN PROCESSING; RAT;

ACETYLCHOLINESTERASE; ADMINISTRATION, INHALATION; AEROSOLS; ANIMALS; ANTIDOTES; BUTYRYLCHOLINESTERASE; HUMANS; INSECTICIDES; LUNG; MACACA; MICE; PARAOXON; RECOMBINANT PROTEINS;

CRICETULUS GRISEUS; MACACA; MUS;

EID: 84875812479     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.11.004     Document Type: Conference Paper

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