A quantitative approach for understanding small-scale human mesenchymal stem cell culture - implications for large-scale bioprocess development

Biotechnology Journal

Volumn 8, Issue 4, 2013, Pages 459-471

  Rafiq, Qasim A ^a   Coopman, Karen ^a   Nienow, Alvin W ^a,b   Hewitt, Christopher J ^a  

^a LOUGHBOROUGH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Bioprocessing; Human mesenchymal stem cells; Hypoxia; Normoxia; Regenerative medicine

Indexed keywords

BIOPROCESSING; HUMAN MESENCHYMAL STEM CELLS; HYPOXIA; NORMOXIA; REGENERATIVE MEDICINE;

BOTTLES; CELL CULTURE; GLUCOSE; HEALTH CARE; MONOLAYERS;

STEM CELLS;

AMMONIA; DISSOLVED OXYGEN; GLUCOSE; LACTIC ACID;

ADIPOGENESIS; ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ARTICLE; BIOPROCESS; BONE DEVELOPMENT; BURST FORMING UNIT E; CELL COUNT; CELL CULTURE; CELL DENSITY; CELL DIFFERENTIATION; CELL GROWTH; CELL POPULATION; CHONDROGENESIS; COLONY FORMING UNIT E; CONTROLLED STUDY; COST CONTROL; CULTURE MEDIUM; GROWTH RATE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL; MONOLAYER CULTURE; NONHUMAN; OXYGEN CONCENTRATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REGENERATIVE MEDICINE; TARGET CELL;

BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELLS, CULTURED; CULTURE MEDIA; GLUCOSE; HUMANS; IMMUNOPHENOTYPING; KINETICS; LACTIC ACID; MESENCHYMAL STROMAL CELLS; OXYGEN; QUATERNARY AMMONIUM COMPOUNDS;

EID: 84875807378     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.201200197     Document Type: Article

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