Hematopoietic progenitors express myelin basic protein and ensheath axons in Shiverer brain

Journal of Neuroimmunology

Volumn 257, Issue 1-2, 2013, Pages 13-20

  Goolsby, James ^a,c   Makar, Tapas ^a,b,c   Dhib Jalbut, Suhayl ^d   Bever, Christopher T ^a,b,c   Pessac, Bernard ^e   Trisler, David ^a,b,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Multiple Sclerosis Center of Excellence   (United States)

^c VAMHCS   (United States)

^d ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^e CNRS   (France)

Author keywords

Bone marrow; Cell therapy; Oligodendroglia; Stem cells; Tissue repair

Indexed keywords

CD34 ANTIGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA; MYELIN BASIC PROTEIN; NEUROFILAMENT H PROTEIN; NEUROFILAMENT PROTEIN; NEURON SPECIFIC NUCLEAR PROTEIN; UNCLASSIFIED DRUG;

ADULT STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MIGRATION; CELL STRUCTURE; CELL TRACKING; CONTROLLED STUDY; EMBRYO; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MOLECULAR IMAGING; MOUSE; MULTIPOTENT STEM CELL; MYELIN SHEATH; NERVE DEGENERATION; NERVE FIBER; NEUROFILAMENT; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; AXONS; BRAIN; CELLS, CULTURED; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE; MICE, INBRED C3H; MICE, NEUROLOGIC MUTANTS; MYELIN BASIC PROTEIN; MYELIN SHEATH;

EID: 84875805144     PISSN: 01655728     EISSN: 18728421     Source Type: Journal    
DOI: 10.1016/j.jneuroim.2013.01.004     Document Type: Article

References (23)

1. Brüstle O., Jones K.N., Learish R.D., Karram K., Choudhary K., Wiestler O.D., Duncan I.D., McKay R.D.G. Embryonic stem cell-derived glial precursors: a source of myelinating transplants. Science 1999, 285:754-756.
2. Cogle C.R., Yachnis A.T., Laywell E.D., Zander D.S., Wingard J.R., Steindler D.A., Scott E.W. Bone marrow transdifferentiation in brain after transplantation: a retrospective study. Lancet 2004, 363:1432-1437.
3. Goolsby J., Marty M.C., Heletz D., Chiapelli J., Fishman P.S., Bever C.T., Pessac B., Trisler D. Haematopoietic progenitors express neural genes. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:14926-14931.
4. Grima B., Zelenika D., Pessac B. A novel transcript overlapping the myelin basic protein gene. J. Neurochem. 1992, 59:2318-2323.
5. Harper J., Krishnan C., Darman J.S., Deshpande D.M., Peck S., Shats I., Backovic S., Rothstein J.D., Kerr D.A. Axonal growth of embryonic stem cell-derived motorneurons in vitro and in motorneuron-injured adult rats. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:7123-7128.
6. Hofstetter C., Schwartz E.J., Hess D., Widenfalk J., El Manira A., Prockop D.J., Olson L. Marrow stromal cells form guiding strands in the injured spinal cord and promote recovery. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:2199-2204.
7. Makar T., Trisler D., Bever C.T., Goolsby J., Sura K., Balasubramanian S., Sultana S., Patel N., Ford D., Singh I., Gupta A., Valenzuela R., Dhib- Jalbut S. Stem cell based delivery of IFN-β reduces relapses in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 2008, 196:67-81.
8. Makar T., Trisler D., Sura K., Sultana S., Patel N., Bever C.T. Brain derived neurotrophic factor treatment reduces apoptosis in experimental allergic encephalomyelitis. J. Neurol. Sci. 2008, 270:70-76.
9. Makar T.K., Bever C.T., Singh I.S., Royal W., Sahu S.N., Sura T.P., Sultana S., Sura K.T., Patel N., Dhib-Jalbut S., Trisler D. Brain-derived neurotrophic factor gene delivery in an animal model of multiple sclerosis using bone marrow stem cells as a vehicle. J. Neuroimmunol. 2009, 210(1-2):40-51.
10. Marty M., Alliot F., Rutin J., Fritz R., Trisler D., Pessac B. The myelin basic protein gene is expressed in differentiated blood cell lineages and in hematopoietic progenitors. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:8856-8861.
11. Mezey E., Key S., Vogelsang G., Szalayova I., Lange G.D., Crain B. Transplanted bone marrow generates new neurons in human brains. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:1364-1369.
12. Mitome M., Low H.P., Van Den Pol A., Nunnari J.J., Wolf M.K., Billings- Gagliardi S., Schwartz W.J. Towards the reconstruction of central nervous system white matter using neural precursor cells. Brain 2001, 124:2147-2161.
13. Pessac B., Bara M.A., Ford D., Patibandla G.K., Trisler D. Hematopoietic progenitors express embryonic stem cell and germ layer genes. Compt. Rendus Biol. 2011, 334:300-306.
14. Pessac B., Nimmagadda V.K., Makar T., Fishman P.S., Bever C.T., Trisler D. Adult hematopoietic progenitors are pluripotent in chimeric mice. Compt. Rendus Biol. 2012, 335:454-462.
15. Pluchino S., Quattrini A., Brambilla E., Gritti A., Salani G., Dina G., Galli R., Del Carro U., Amadio S., Bergami A., Furlan R., Comi G., Vescovi A.l, Martino G. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 2003, 422:688-694.
16. Sigurjonsson O., Perreault M.-C., Egeland T., Glover J. Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:5227-5232.
17. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
18. Trisler D., Rutin J., Pessac B. Retinal engineering: engrafted neural cell lines locate in appropriate layers. Proc. Natl. Acad. Sci. U.S.A. 1996, 93:6269-6274.
19. Vignais L., Nait Oumesmar B., Mellouk F., Gout O., Labourdette G., Baron- Van Evercooren A., Gumpel M. Transplantation of oligodendrocyte precursors in the adult demyelinated spinal cord: migration and remyelination. Int. J. Dev. Neurosci. 1993, 11:603-612.
20. Wernig M., Meissner A., Cassady J.P., Jaenisch R. c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2008, 2:10-12.
21. Wichterle H., Lieberam I., Porter J.A., Jessell T.M. Directed differentiation of embryonic stem into motorneurons. Cell 2002, 110:385-397.
22. Yandava B., Billingshurst L., Snyder E. "Global" cell replacement is feasible via neural stem cell transplantation: evidence from dysmyelinated Shiverer mouse brain. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:7029-7034.
23. Zelenika D., Grima B., Pessac B. A new family of transcripts of the myelin basic protein gene: expression in brain and in immune system. J. Neurochem. 1993, 60:1574-1577.