Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage

Chemico-Biological Interactions

Volumn 203, Issue 1, 2013, Pages 208-211

  Gao, Yang ^a   Geng, Liyi ^a   Orson, Frank ^b,c,d   Kinsey, Berma ^b,d   Kosten, Thomas R ^b,c,d   Shen, Xiaoyun ^b,d   Brimijoin, Stephen ^a  

^a MAYO GRADUATE SCHOOL   (United States)

^b Department of Medicine ^*  (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Alanine transaminase; Anti cocaine vaccine; Cocaine toxicity; Grip strength; Histopathology; Mouse

Indexed keywords

CARBOXYLESTERASE; COCAINE; COCAINE ANTIBODY; DRUG ANTIBODY; PARVOVIRUS VECTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; COCAINE TOXICITY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG INTOXICATION; DRUG POTENTIATION; GENETIC TRANSDUCTION; IN VIVO STUDY; LIVER PROTECTION; LIVER TOXICITY; MALE; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; MOUSE; MUSCLE WEAKNESS; NONHUMAN; RAT; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BUTYRYLCHOLINESTERASE; COCAINE; COCAINE-RELATED DISORDERS; DEPENDOVIRUS; DRUG-INDUCED LIVER INJURY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; HYDROLASES; MALE; MICE; MICE, INBRED BALB C; MUSCLE STRENGTH; RATS; VACCINES;

MUS; RATTUS;

EID: 84875803205     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.08.006     Document Type: Conference Paper

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