Evaluation of the performance of the reduced local lymph node assay for skin sensitization testing

Regulatory Toxicology and Pharmacology

Volumn 66, Issue 1, 2013, Pages 66-71

  Ezendam, Janine ^a   Muller, Andre ^a   Hakkert, Betty C ^a   van Loveren, Henk ^a,b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Predictivity; REACH; Reduced local lymph node assay; Skin sensitization

Indexed keywords

2 ANISIDE; 2 METHYLOCTANE 1,8 DIAMINE; 2,3,5,6 TETRACHLOROPYRIDINE; CHEMICAL COMPOUND; CLOQUINTOCET MEXYL; FLUORONICOMETHANOL; IRRITANT AGENT; UNCLASSIFIED DRUG; VINYLENE CARBONATE;

ACCURACY; ANALYTIC METHOD; ANALYTICAL ERROR; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL STRUCTURE; CLASSIFICATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; DATA ANALYSIS; DATA BASE; EVALUATION RESEARCH; EXPERIMENTAL MOUSE; FALSE NEGATIVE RESULT; INTERMETHOD COMPARISON; LIMIT OF DETECTION; LOCAL LYMPH NODE ASSAY; PERFORMANCE MEASUREMENT SYSTEM; PRIORITY JOURNAL; REDUCED LOCAL LYMPH NODE ASSAY; SENSITIVITY AND SPECIFICITY; SKIN SENSITIZATION; SYSTEMATIC ERROR;

ANIMALS; DATABASES, FACTUAL; DOSE-RESPONSE RELATIONSHIP, DRUG; IRRITANTS; LOCAL LYMPH NODE ASSAY; MICE; SKIN;

ANIMALIA; MUS;

EID: 84875801895     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2013.02.006     Document Type: Article

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