Variable contributions of basic residues forming an APC exosite in the binding and inactivation of factor VIIIa

Biochemistry

Volumn 52, Issue 13, 2013, Pages 2228-2235

  Takeyama, Masahiro ^a   Wintermute, Jennifer M ^a   Manithody, Chandrashekhara ^b   Rezaie, Alireza R ^b   Fay, Philip J ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; AFFINITY VALUES; BINDING AFFINITIES; BINDING INTERACTION; KINETIC ANALYSIS; RATE REDUCTION; SUBSTRATE CONCENTRATIONS; WESTERN BLOTTING;

BINDING ENERGY; SUBSTRATES;

SURFACE PLASMON RESONANCE;

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10A; RECOMBINANT BLOOD CLOTTING FACTOR 8;

ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; SURFACE PLASMON RESONANCE;

AMINO ACID SUBSTITUTION; BINDING SITES; FACTOR VIIIA; GENE EXPRESSION; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN C; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS;

EID: 84875797787     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301632g     Document Type: Article

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