Orally disintegrating tablets prepared by a co-processed mixture of micronized crospovidone and mannitol using a ball mill to improve compactibility and tablet stability

Powder Technology

Volumn 241, Issue , 2013, Pages 60-66

  Katsuno, Eri ^a   Tahara, Kohei ^a   Takeuchi, Yoshiko ^a   Takeuchi, Hirofumi ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Cogrinding; Crospovidone; Direct compression; Mannitol; Rapidly disintegrating tablets

Indexed keywords

CO-GRINDING; CROSPOVIDONE; DIRECT COMPRESSION; MANNITOL; RAPIDLY DISINTEGRATING TABLETS;

BALL MILLING; BALL MILLS; DRUG PRODUCTS; POLYOLS; STABILITY; TENSILE STRENGTH;

MIXTURES;

CROSPOVIDONE; MANNITOL; PARACETAMOL;

ARTICLE; BALL MILLING; CONTROLLED STUDY; DRUG STABILITY; DRUG STORAGE; MORPHOLOGY; ORALLY DISINTEGRATING TABLET; PARTICLE SIZE; PHARMACOLOGICAL PROCEDURES; PHYSICAL CHEMISTRY; POWDER; TABLET; TABLET DISINTEGRATION; TABLET HARDNESS; TENSILE STRENGTH; WETTABILITY;

EID: 84875797576     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2013.03.008     Document Type: Article

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