Impaired bioavailability and antiplatelet effect of high-dose clopidogrel in patients after cardiopulmonary resuscitation (CPR)

European Journal of Clinical Pharmacology

Volumn 69, Issue 3, 2013, Pages 309-317

  Souckova L ^a   Opatrilova R ^c   Suk, P ^a,b   Cundrle Jr I ^a,b   Pavlik M ^a,b   Zvonicek V ^a,b   Hlinomaz, O ^a,b   Sramek V ^a,b  

^a ST ANNE S UNIVERSITY HOSPITAL   (Czech Republic)

^b MASARYK UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

Author keywords

Clopidogrel; HPLC; Pharmacokinetics; Thrombelastography

Indexed keywords

CLOPIDOGREL;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTIFICIAL VENTILATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY STENT; CRITICALLY ILL PATIENT; DRUG BIOAVAILABILITY; DRUG MEGADOSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INDUCED HYPOTHERMIA; LOADING DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; NASOGASTRIC TUBE; PHARMACODYNAMICS; PRIORITY JOURNAL; RESUSCITATION; REVIEW; THROMBOCYTE AGGREGATION INHIBITION; THROMBOELASTOGRAPH; THROMBOELASTOGRAPHY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; BIOLOGICAL AVAILABILITY; BLOOD PLATELETS; CARDIOPULMONARY RESUSCITATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRITICAL ILLNESS; FEMALE; HUMANS; HYPOTHERMIA, INDUCED; INTUBATION, GASTROINTESTINAL; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PLATELET AGGREGATION INHIBITORS; PURINERGIC P2 RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2; RESPIRATION, ARTIFICIAL; STENTS; TABLETS; THROMBELASTOGRAPHY; TICLOPIDINE;

EID: 84875790111     PISSN: 00316970     EISSN: 14321041     Source Type: Journal    
DOI: 10.1007/s00228-012-1360-0     Document Type: Review

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