Hypothermic anticoagulation: Testing individual responses to graded severe hypothermia with thromboelastography

Blood Coagulation and Fibrinolysis

Volumn 23, Issue 4, 2012, Pages 285-289

  Ruzicka, Jiri ^a   Stengl, Milan ^a   Bolek, Lukas ^a   Benes, Jiri ^a   Matejovic, Martin ^a   Krouzecky, Ales ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

coagulation; extracorporeal circulation; temperature; thromboelastography

Indexed keywords

ARTICLE; BLOOD CLOTTING; BLOOD TEMPERATURE; HEMATOLOGICAL PROCEDURE; HYPOTHERMIA; MATHEMATICAL MODEL; PRIORITY JOURNAL; TEMPERATURE; TEMPERATURE DEPENDENCE; THROMBOELASTOGRAPHY; TREATMENT RESPONSE;

ADULT; BLOOD COAGULATION; FEMALE; HUMANS; HYPOTHERMIA; HYPOTHERMIA, INDUCED; MALE; MIDDLE AGED; MODELS, BIOLOGICAL; THROMBELASTOGRAPHY; YOUNG ADULT;

EID: 84861094244     PISSN: 09575235     EISSN: 14735733     Source Type: Journal    
DOI: 10.1097/MBC.0b013e328351885a     Document Type: Article

References (9)

1. Wolberg AS, Meng ZH, Monroe DM, Hoffman M. A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function. J Trauma 2004;56:1221-1228.
2. Martini WZ. The effects of hypothermia on fibrinogen metabolism and coagulation function in swine. Metabolism 2007;56:214-221.
3. Rohrer MJ, Natale AM. Effect of hypothermia on the coagulation cascade. Crit Care Med 1992;20:1402-1414.
4. Nielsen VG, George SJ. Carbon monoxide releasing molecule-2 attenuates the anticoagulant and amplifies the hypofibrinolytic effects of hypothermia in human plasma in vitro. Blood Coagul Fibrinolysis 2011;22:67-72.
5. Watts DD, Trask A, Soeken K, Perdue P, Dols S, Kaufmann C. Hypothermic coagulopathy in trauma: effect of varying levels of hypothermia on enzyme speed, platelet function, and fibrinolytic activity. J Trauma 1998;44:846-854.
6. DeLoughery TG. Coagulation defects in trauma patients: etiology, recognition and therapy. Crit Care Clin 2004;20:13-24.
7. Rundgren M, Engstrom M. A thomboelastometric evaluation of the effects of hypothermia and the coagulation system. Anesth Analg 2008;107:1465-1468.
8. Krouzecky A, Chvojka J, Sykora R, et al. Regional cooling of the extracorporeal blood circuit: a novel anticoagulation approach for renal replacement therapy? Intensive Care Med 2009;35:364-370.
9. Krouzecky A, Chvojka J, Sykora R, Radej J, Karvunidis T, Novak I, et al. The safety and efficacy of a new anticoagulation strategy using selective in-circuit blood cooling during haemofiltration: an experimental study. Nephrol Dial Transplant 2011;26:1622-1627.