SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 8, 2013, Pages 2250-2261

Design and synthesis of novel pyrimido[4,5-b]azepine derivatives as HER2/EGFR dual inhibitors

(12) Kawakita, Youichi a Seto, Masaki a Ohashi, Tomohiro a Tamura, Toshiya a Yusa, Tadashi a Miki, Hiroshi a Iwata, Hidehisa a Kamiguchi, Hidenori a Tanaka, Toshimasa a Sogabe, Satoshi a Ohta, Yoshikazu a Ishikawa, Tomoyasu a

a TAKEDA PHARMACEUTICAL COMPANY LIMITED (Japan)

Author keywords

EGFR; HER2; Pyrimido 4,5 b azepine

Indexed keywords

1 BENZOTHIOPHEN 4 YLOXY GROUP; 4 [[3 CHLORO 4 [3 (TRIFLUOROMETHYL)PHENOXY]PHENYL]AMINO] N [2 (METHYLSULFONYL)ETHYL] 8,9 DIHYDRO 7H PYRIMIDO[4,5 B]AZEPINE 6 CARBOXAMIDE; 4 [[4 (1 BENZOTHIOPHEN 4 YLOXY) 3 CHLOROPHENYL]AMINO] N (2-HYDROXYETHYL) 8,9 DIHYDRO 7H PYRIMIDO[4,5 B]AZEPINE 6 CARBOXAMIDE; 4 ANILO GROUP; AMIDE; CARBONYL DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MOLECULAR SCAFFOLD; NITROGEN; PROTON; PYRIMIDO[4,5 B]AZEPINE DERIVATIVE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN INHIBITOR;

ARTICLE; CLAISEN CONDENSATION; CONTROLLED STUDY; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; MELTING POINT; STRUCTURE ACTIVITY RELATION;

AZEPINES; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CRYSTALLOGRAPHY, X-RAY; FEMALE; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84875754212 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2013.02.014 Document Type: Article

Times cited : (57)

References (37)

1
- 0021055658
- T. Yamamoto, T. Nishida, N. Miyajima, S. Kawai, T. Ooi, and K. Toyoshima Cell 35 1983 71
- (1983) Cell , vol.35 , pp. 71
- Yamamoto, T.¹ Nishida, T.² Miyajima, N.³ Kawai, S.⁴ Ooi, T.⁵ Toyoshima, K.⁶

2
- 0037399412
- P. Traxler Expert Opin. Ther. Targets 7 2003 215
- (2003) Expert Opin. Ther. Targets , vol.7 , pp. 215
- Traxler, P.¹

3
- 0036682301
- B. Nagar, W.G. Bornmann, P. Pellicena, T. Schindler, D.R. Veach, W.T. Miller, B. Clarkson, and J. Kuriyan Cancer Res. 62 2002 4236
- (2002) Cancer Res. , vol.62 , pp. 4236
- Nagar, B.¹ Bornmann, W.G.² Pellicena, P.³ Schindler, T.⁴ Veach, D.R.⁵ Miller, W.T.⁶ Clarkson, B.⁷ Kuriyan, J.⁸

4
- 33746196584
- K.G. Petrov, Y.M. Zhang, M. Carter, G.S. Cockerill, S. Dickerson, C.A. Gauthier, Y. Guo, R.A. Mook Jr., D.W. Rusnak, A.L. Walker, E.R. Wood, and K.E. Lackey Bioorg. Med. Chem. Lett. 16 2006 4686
- (2006) Bioorg. Med. Chem. Lett. , vol.16 , pp. 4686
- Petrov, K.G.¹ Zhang, Y.M.² Carter, M.³ Cockerill, G.S.⁴ Dickerson, S.⁵ Gauthier, C.A.⁶ Guo, Y.⁷ Mook, Jr.R.A.⁸ Rusnak, D.W.⁹ Walker, A.L.¹⁰ Wood, E.R.¹¹ Lackey, K.E.¹²

5
- 0013297123
- Tykerb (Lapatinib); GlaxoSmithKline: Research Triangle Park, NC 27709, USA
- Package Insert. Tykerb (Lapatinib); GlaxoSmithKline: Research Triangle Park, NC 27709, USA, 2010.
- (2010) Package Insert

6
- 80054057131
- 10.1093/annonc/mdr021 Epub ahead of print
- S. Iqbal, B. Goldman, C.M. Fenoglio-Preiser, H.J. Lenz, W. Zhang, K.D. Danenberg, S.I. Shibata, and C.D. Blanke Ann. Oncol. 2011 10.1093/annonc/mdr021 Epub ahead of print
- (2011) Ann. Oncol.
- Iqbal, S.¹ Goldman, B.² Fenoglio-Preiser, C.M.³ Lenz, H.J.⁴ Zhang, W.⁵ Danenberg, K.D.⁶ Shibata, S.I.⁷ Blanke, C.D.⁸

7
- 84866906718
- 10.1016/j.urolonc.2010.09.018 Epub ahead of print
- Y.E. Whang, A.J. Armstrong, W.K. Rathmell, P.A. Godley, W.Y. Kim, R.S. Pruthi, E.M. Wallen, J.M. Crane, D.T. Moore, G. Grigson, K. Morris, C.P. Watkins, and D.J. George Urol. Oncol. 2011 10.1016/j.urolonc.2010.09.018 Epub ahead of print
- (2011) Urol. Oncol.
- Whang, Y.E.¹ Armstrong, A.J.² Rathmell, W.K.³ Godley, P.A.⁴ Kim, W.Y.⁵ Pruthi, R.S.⁶ Wallen, E.M.⁷ Crane, J.M.⁸ Moore, D.T.⁹ Grigson, G.¹⁰ Morris, K.¹¹ Watkins, C.P.¹² George, D.J.¹³

8
- 79958856696
- 10.1002/ijc.25896 Epub ahead of print
- K. Mimura, K. Kono, T. Maruyama, M. Watanabe, S. Izawa, S. Shiba, Y. Mizukami, Y. Kawaguchi, M. Inoue, T. Kono, A. Choudhury, R. Kiessling, and H. Fujii Int. J. Cancer 2011 10.1002/ijc.25896 Epub ahead of print
- (2011) Int. J. Cancer
- Mimura, K.¹ Kono, K.² Maruyama, T.³ Watanabe, M.⁴ Izawa, S.⁵ Shiba, S.⁶ Mizukami, Y.⁷ Kawaguchi, Y.⁸ Inoue, M.⁹ Kono, T.¹⁰ Choudhury, A.¹¹ Kiessling, R.¹² Fujii, H.¹³

9
- 77949694139
- H.J. Ross, G.R. Blumenschein Jr., J. Aisner, N. Damjanov, A. Dowlati, J. Garst, J.R. Rigas, M. Smylie, H. Hassani, K.E. Allen, L. Leopold, T.Z. Zaks, and F.A. Shepherd Clin. Cancer Res. 16 2010 1938
- (2010) Clin. Cancer Res. , vol.16 , pp. 1938
- Ross, H.J.¹ Blumenschein, Jr.G.R.² Aisner, J.³ Damjanov, N.⁴ Dowlati, A.⁵ Garst, J.⁶ Rigas, J.R.⁷ Smylie, M.⁸ Hassani, H.⁹ Allen, K.E.¹⁰ Leopold, L.¹¹ Zaks, T.Z.¹² Shepherd, F.A.¹³

10
- 3343024502
- A. Ooi, T. Takehana, X. Li, S. Suzuki, K. Kunitomo, H. Iino, H. Fujii, Y. Takeda, and Y. Dobashi Mod. Pathol. 17 2004 895
- (2004) Mod. Pathol. , vol.17 , pp. 895
- Ooi, A.¹ Takehana, T.² Li, X.³ Suzuki, S.⁴ Kunitomo, K.⁵ Iino, H.⁶ Fujii, H.⁷ Takeda, Y.⁸ Dobashi, Y.⁹

11
- 13944262091
- H.-R. Tsou, E.G. Overbeek-Klumpers, W.A. Hallett, M.F. Reich, M.B. Floyd, B.D. Johnson, R.S. Michalak, R. Nilakantan, C. Discafani, J. Golas, S.K. Rabindran, R. Shen, X. Shi, Y.-F. Wang, J. Upeslacis, and A. Wissner J. Med. Chem. 48 2005 1107
- (2005) J. Med. Chem. , vol.48 , pp. 1107
- Tsou, H.-R.¹ Overbeek-Klumpers, E.G.² Hallett, W.A.³ Reich, M.F.⁴ Floyd, M.B.⁵ Johnson, B.D.⁶ Michalak, R.S.⁷ Nilakantan, R.⁸ Discafani, C.⁹ Golas, J.¹⁰ Rabindran, S.K.¹¹ Shen, R.¹² Shi, X.¹³ Wang, Y.-F.¹⁴ Upeslacis, J.¹⁵ Wissner, A.¹⁶

12
- 34347208648
- D. Li, T. Shimamura, H. Ji, L. Chen, H.J. Haringsma, K. McNamara, M.-C. Liang, S.A. Perera, S. Zaghlul, C.L. Borgman, S. Kubo, M. Takahashi, Y. Sun, L.R. Chirieac, R.F. Padera, N.I. Lindeman, P.A. Jänne, R.K. Thomas, M.L. Meyerson, M.J. Eck, J.A. Engelman, G.I. Shapiro, and K.-K. Wong Cancer Cell. 12 2007 81
- (2007) Cancer Cell. , vol.12 , pp. 81
- Li, D.¹ Shimamura, T.² Ji, H.³ Chen, L.⁴ Haringsma, H.J.⁵ McNamara, K.⁶ Liang, M.-C.⁷ Perera, S.A.⁸ Zaghlul, S.⁹ Borgman, C.L.¹⁰ Kubo, S.¹¹ Takahashi, M.¹² Sun, Y.¹³ Chirieac, L.R.¹⁴ Padera, R.F.¹⁵ Lindeman, N.I.¹⁶ Jänne, P.A.¹⁷ Thomas, R.K.¹⁸ Meyerson, M.L.¹⁹ Eck, M.J.²⁰ more..

13
- 38049038935
- F.A.L.M. Eskens, C.H. Mom, A.S.T. Planting, J.A. Gietema, A. Amelsberg, H. Huisman, L. van Doorn, H. Burger, P. Stopfer, J. Verweij, and E.G. de Vries Br. J. Cancer 98 2008 80
- (2008) Br. J. Cancer , vol.98 , pp. 80
- Eskens, F.A.L.M.¹ Mom, C.H.² Planting, A.S.T.³ Gietema, J.A.⁴ Amelsberg, A.⁵ Huisman, H.⁶ Van Doorn, L.⁷ Burger, H.⁸ Stopfer, P.⁹ Verweij, J.¹⁰ De Vries, E.G.¹¹

14
- 20944433324
- K. Yokoi, P.H. Thaker, S. Yazici, R.R. Rebhun, D.-H. Nam, J. He, S.-J. Kim, J.L. Abbruzzese, S.R. Hamilton, and I.J. Fidler Cancer Res. 65 2005 3716
- (2005) Cancer Res. , vol.65 , pp. 3716
- Yokoi, K.¹ Thaker, P.H.² Yazici, S.³ Rebhun, R.R.⁴ Nam, D.-H.⁵ He, J.⁶ Kim, S.-J.⁷ Abbruzzese, J.L.⁸ Hamilton, S.R.⁹ Fidler, I.J.¹⁰

15
- 33750708563
- T.W. Wong, F.Y. Lee, C. Yu, F.R. Luo, S. Oppenheimer, H. Zhang, R.A. Smykla, H. Mastalerz, B.E. Fink, J.T. Hunt, A.V. Gavai, and G.D. Vite Clin. Cancer Res. 12 2006 6186
- (2006) Clin. Cancer Res. , vol.12 , pp. 6186
- Wong, T.W.¹ Lee, F.Y.² Yu, C.³ Luo, F.R.⁴ Oppenheimer, S.⁵ Zhang, H.⁶ Smykla, R.A.⁷ Mastalerz, H.⁸ Fink, B.E.⁹ Hunt, J.T.¹⁰ Gavai, A.V.¹¹ Vite, G.D.¹²

16
- 33847792225
- H. Mastalerz, M. Chang, P. Chen, P. Dextraze, B.E. Fink, A. Gavai, B. Goyal, W.-C. Han, W. Johnson, D. Langley, F.Y. Lee, P. Marathe, A. Mathur, S. Oppenheimer, E. Ruediger, J. Tarrant, J.S. Tokarski, G.D. Vite, D.M. Vyas, H. Wong, T.W. Wong, H. Zhang, and G. Zhang Bioorg. Med. Chem. Lett. 17 2007 2036
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 2036
- Mastalerz, H.¹ Chang, M.² Chen, P.³ Dextraze, P.⁴ Fink, B.E.⁵ Gavai, A.⁶ Goyal, B.⁷ Han, W.-C.⁸ Johnson, W.⁹ Langley, D.¹⁰ Lee, F.Y.¹¹ Marathe, P.¹² Mathur, A.¹³ Oppenheimer, S.¹⁴ Ruediger, E.¹⁵ Tarrant, J.¹⁶ Tokarski, J.S.¹⁷ Vite, G.D.¹⁸ Vyas, D.M.¹⁹ Wong, H.²⁰ more..

17
- 34247507263
- H. Mastalerz, M. Chang, A. Gavai, W. Johnson, D. Langley, F.Y. Lee, P. Marathe, A. Mathur, S. Oppenheimer, J. Tarrant, J.S. Tokarski, G.D. Vite, D.M. Vyas, H. Wong, T.W. Wong, H. Zhang, and G. Zhang Bioorg. Med. Chem. Lett. 17 2007 2828
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 2828
- Mastalerz, H.¹ Chang, M.² Gavai, A.³ Johnson, W.⁴ Langley, D.⁵ Lee, F.Y.⁶ Marathe, P.⁷ Mathur, A.⁸ Oppenheimer, S.⁹ Tarrant, J.¹⁰ Tokarski, J.S.¹¹ Vite, G.D.¹² Vyas, D.M.¹³ Wong, H.¹⁴ Wong, T.W.¹⁵ Zhang, H.¹⁶ Zhang, G.¹⁷

18
- 34547611405
- H. Mastalerz, M. Chang, P. Chen, B.E. Fink, A. Gavai, W.C. Han, W. Johnson, D. Langley, F.Y. Lee, K. Leavitt, P. Marathe, D. Norris, S. Oppenheimer, B. Sleczka, J. Tarrant, J.S. Tokarski, G.D. Vite, D.M. Vyas, H. Wong, T.W. Wong, H. Zhang, and G. Zhang Bioorg. Med. Chem. Lett. 17 2007 4947
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 4947
- Mastalerz, H.¹ Chang, M.² Chen, P.³ Fink, B.E.⁴ Gavai, A.⁵ Han, W.C.⁶ Johnson, W.⁷ Langley, D.⁸ Lee, F.Y.⁹ Leavitt, K.¹⁰ Marathe, P.¹¹ Norris, D.¹² Oppenheimer, S.¹³ Sleczka, B.¹⁴ Tarrant, J.¹⁵ Tokarski, J.S.¹⁶ Vite, G.D.¹⁷ Vyas, D.M.¹⁸ Wong, H.¹⁹ Wong, T.W.²⁰ Zhang, H.²¹ Zhang, G.²² more..

19
- 0037676025
- S.K. Bhattacharya, E.D. Cox, J.C. Kath, A.M. Mathiowetz, J. Morris, J.D. Moyer, L.R. Pustilnik, K. Rafidi, D.T. Richter, C. Su, and M.D. Wessel Biochem. Biophys. Res. Commun. 307 2003 267
- (2003) Biochem. Biophys. Res. Commun. , vol.307 , pp. 267
- Bhattacharya, S.K.¹ Cox, E.D.² Kath, J.C.³ Mathiowetz, A.M.⁴ Morris, J.⁵ Moyer, J.D.⁶ Pustilnik, L.R.⁷ Rafidi, K.⁸ Richter, D.T.⁹ Su, C.¹⁰ Wessel, M.D.¹¹

20
- 35448955219
- J.P. Jani, R.S. Finn, M. Campbell, K.G. Coleman, R.D. Connell, N. Currier, E.O. Emerson, E. Floyd, S. Harriman, J.C. Kath, J. Morris, J.D. Moyer, L.R. Pustilnik, K. Rafidi, S. Ralston, A.M. Rossi, S.J. Steyn, L. Wagner, S.M. Winter, and S.K. Bhattacharya Cancer Res. 67 2007 9887
- (2007) Cancer Res. , vol.67 , pp. 9887
- Jani, J.P.¹ Finn, R.S.² Campbell, M.³ Coleman, K.G.⁴ Connell, R.D.⁵ Currier, N.⁶ Emerson, E.O.⁷ Floyd, E.⁸ Harriman, S.⁹ Kath, J.C.¹⁰ Morris, J.¹¹ Moyer, J.D.¹² Pustilnik, L.R.¹³ Rafidi, K.¹⁴ Ralston, S.¹⁵ Rossi, A.M.¹⁶ Steyn, S.J.¹⁷ Wagner, L.¹⁸ Winter, S.M.¹⁹ Bhattacharya, S.K.²⁰ more..

21
- 23044509202
- D.H.B. Ripin, D.E. Bourassa, T. Brandt, M.J. Castaldi, H.N. Frost, J. Hawkins, P.J. Johnson, S.S. Massett, K. Neumann, J. Phillips, J.W. Raggon, P.R. Rose, J.L. Rutherford, B. Sitter, A.M. Stewart III, M.G. Vetelino, and L. Wei Org. Process Res. Dev. 9 2005 440
- (2005) Org. Process Res. Dev. , vol.9 , pp. 440
- Ripin, D.H.B.¹ Bourassa, D.E.² Brandt, T.³ Castaldi, M.J.⁴ Frost, H.N.⁵ Hawkins, J.⁶ Johnson, P.J.⁷ Massett, S.S.⁸ Neumann, K.⁹ Phillips, J.¹⁰ Raggon, J.W.¹¹ Rose, P.R.¹² Rutherford, J.L.¹³ Sitter, B.¹⁴ Stewart Iii, A.M.¹⁵ Vetelino, M.G.¹⁶ Wei, L.¹⁷

22
- 34248176943
- B. Lippa, G.S. Kauffman, J. Arcari, T. Kwan, J. Chen, W. Hungerford, S. Bhattacharya, X. Zhao, C. Williams, J. Xiao, L. Pustilnik, C. Su, J.D. Moyer, L. Ma, M. Campbell, and S. Steyn Bioorg. Med. Chem. Lett. 17 2007 3081
- (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 3081
- Lippa, B.¹ Kauffman, G.S.² Arcari, J.³ Kwan, T.⁴ Chen, J.⁵ Hungerford, W.⁶ Bhattacharya, S.⁷ Zhao, X.⁸ Williams, C.⁹ Xiao, J.¹⁰ Pustilnik, L.¹¹ Su, C.¹² Moyer, J.D.¹³ Ma, L.¹⁴ Campbell, M.¹⁵ Steyn, S.¹⁶

23
- 82555187407
- T. Ishikawa, M. Seto, H. Banno, Y. Kawakita, M. Oorui, T. Taniguchi, Y. Ohta, T. Tamura, A. Nakayama, H. Miki, H. Kamiguchi, T. Tanaka, N. Habuka, S. Sogabe, K. Aertgeerts, and K. Kamiyama J. Med. Chem. 54 2011 8030
- (2011) J. Med. Chem. , vol.54 , pp. 8030
- Ishikawa, T.¹ Seto, M.² Banno, H.³ Kawakita, Y.⁴ Oorui, M.⁵ Taniguchi, T.⁶ Ohta, Y.⁷ Tamura, T.⁸ Nakayama, A.⁹ Miki, H.¹⁰ Kamiguchi, H.¹¹ Tanaka, T.¹² Habuka, N.¹³ Sogabe, S.¹⁴ Aertgeerts, K.¹⁵ Kamiyama, K.¹⁶

24
- 84860292953
- T. Doi, H. Takiuchi, A. Ohtsu, N. Fuse, M. Goto, M. Yoshida, N. Dote, Y. Kuze, F. Jinno, M. Fujimoto, T. Takubo, N. Nakayama, and R. Tsutsumi Br. J. Can. 106 2012 1
- (2012) Br. J. Can. , vol.106 , pp. 1
- Doi, T.¹ Takiuchi, H.² Ohtsu, A.³ Fuse, N.⁴ Goto, M.⁵ Yoshida, M.⁶ Dote, N.⁷ Kuze, Y.⁸ Jinno, F.⁹ Fujimoto, M.¹⁰ Takubo, T.¹¹ Nakayama, N.¹² Tsutsumi, R.¹³

25
- 79956310563
- K. Aertgeerts, R. Skene, J. Yano, B. Sang, H. Zou, G. Snell, A. Jennings, K. Iwamoto, N. Habuka, A. Hirokawa, T. Ishikawa, T. Tanaka, H. Miki, Y. Ohta, and S. Sogabe J. Biol. Chem. 21 2011 18756
- (2011) J. Biol. Chem. , vol.21 , pp. 18756
- Aertgeerts, K.¹ Skene, R.² Yano, J.³ Sang, B.⁴ Zou, H.⁵ Snell, G.⁶ Jennings, A.⁷ Iwamoto, K.⁸ Habuka, N.⁹ Hirokawa, A.¹⁰ Ishikawa, T.¹¹ Tanaka, T.¹² Miki, H.¹³ Ohta, Y.¹⁴ Sogabe, S.¹⁵

26
- 8844265387
- T. Ikemoto, T. Ito, A. Nishiguchi, and K. Tomimatsu Tetrahedron 60 2004 10851 10857
- (2004) Tetrahedron , vol.60 , pp. 10851-10857
- Ikemoto, T.¹ Ito, T.² Nishiguchi, A.³ Tomimatsu, K.⁴

27
- 8844253030
- T. Ikemoto, T. Ito, A. Nishiguchi, and K. Tomimatsu Tetrahedron Lett. 45 2004 9335 9339
- (2004) Tetrahedron Lett. , vol.45 , pp. 9335-9339
- Ikemoto, T.¹ Ito, T.² Nishiguchi, A.³ Tomimatsu, K.⁴

28
- 10444259767
- M. Seto, N. Miyamoto, K. Aikawa, Y. Aramaki, N. Kanzaki, Y. Iizawa, M. Baba, and M. Shiraishi Bioorg. Med. Chem. 13 2005 363 386
- (2005) Bioorg. Med. Chem. , vol.13 , pp. 363-386
- Seto, M.¹ Miyamoto, N.² Aikawa, K.³ Aramaki, Y.⁴ Kanzaki, N.⁵ Iizawa, Y.⁶ Baba, M.⁷ Shiraishi, M.⁸

29
- 37049112611
- J. Clark, B. Parvizi, and W.I. Southon J. Chem. Soc., Perkin Trans. 1 2 1976 125
- (1976) J. Chem. Soc., Perkin Trans. 1 , vol.2 , pp. 125
- Clark, J.¹ Parvizi, B.² Southon, W.I.³

30
- 84860305840
- Y. Kawakita, H. Banno, T. Ohashi, T. Tamura, T. Yusa, A. Nakayama, H. Miki, H. Iwata, H. Kamiguchi, T. Tanaka, N. Habuka, S. Sogabe, Y. Ohta, and T. Ishikawa J. Med. Chem. 55 2012 3975
- (2012) J. Med. Chem. , vol.55 , pp. 3975
- Kawakita, Y.¹ Banno, H.² Ohashi, T.³ Tamura, T.⁴ Yusa, T.⁵ Nakayama, A.⁶ Miki, H.⁷ Iwata, H.⁸ Kamiguchi, H.⁹ Tanaka, T.¹⁰ Habuka, N.¹¹ Sogabe, S.¹² Ohta, Y.¹³ Ishikawa, T.¹⁴

31
- 79952096135
- H. Iwata, S. Imamura, A. Hori, M.S. Hixon, H. Kimura, and H. Miki Biochemistry 50 2011 738
- (2011) Biochemistry , vol.50 , pp. 738
- Iwata, H.¹ Imamura, S.² Hori, A.³ Hixon, M.S.⁴ Kimura, H.⁵ Miki, H.⁶

32
- 0031059866
- Z. Otwinowski, and W. Minor Methods Enzymol. 276 1997 307
- (1997) Methods Enzymol. , vol.276 , pp. 307
- Otwinowski, Z.¹ Minor, W.²

33
- 0000560808
- A. Vagin, and A. Teplyakov J. Appl. Crystallogr. 30 1997 1022
- (1997) J. Appl. Crystallogr. , vol.30 , pp. 1022
- Vagin, A.¹ Teplyakov, A.²

34
- 0000625192
- S. Bailey Acta Crystallogr. D50 1994 760
- (1994) Acta Crystallogr. , vol.50 D , pp. 760
- Bailey, S.¹

35
- 77949535720
- P. Emsley, B. Lohkamp, W.G. Scott, and K. Cowtan Acta Crystallogr. D66 2010 486
- (2010) Acta Crystallogr. , vol.66 D , pp. 486
- Emsley, P.¹ Lohkamp, B.² Scott, W.G.³ Cowtan, K.⁴

36
- 0030924992
- G.N. Murshudov, A.A. Vagin, and E.J. Dodson Acta Crystallogr. D53 1997 240
- (1997) Acta Crystallogr. , vol.53 D , pp. 240
- Murshudov, G.N.¹ Vagin, A.A.² Dodson, E.J.³

37
- 74549178560
- V.B. Chen, W.B. Arendall 3rd, J.J. Headd, D.A. Keedy, R.M. Immormino, G.J. Kapral, L.W. Murray, J.S. Richardson, and D.C. Richardson Acta Crystallogr. D66 2010 12
- (2010) Acta Crystallogr. , vol.66 D , pp. 12
- Chen, V.B.¹ Arendall III, W.B.² Headd, J.J.³ Keedy, D.A.⁴ Immormino, R.M.⁵ Kapral, G.J.⁶ Murray, L.W.⁷ Richardson, J.S.⁸ Richardson, D.C.⁹

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