How are fragments optimized? A retrospective analysis of 145 fragment optimizations

Journal of Medicinal Chemistry

Volumn 56, Issue 6, 2013, Pages 2478-2486

  Ferenczy, György G ^a   Keseru, György M ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b GEDEON RICHTER LTD   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DETERMINATION; DRUG INDUSTRY; FRAGMENTATION REACTION; LIPOPHILICITY; NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; REACTION OPTIMIZATION; RETROSPECTIVE STUDY; UNIVERSITY; X RAY ANALYSIS;

DRUG DISCOVERY; HUMANS; LIGANDS; PHYSICOCHEMICAL PROCESSES; RETROSPECTIVE STUDIES;

EID: 84875727654     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm301851v     Document Type: Article

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