Minor cognitive impairments in cancer patients magnify the effect of caregiver preferences on end-of-life care

Journal of Pain and Symptom Management

Volumn 45, Issue 4, 2013, Pages 650-659

  Gao, Xin ^a,b   Prigerson, Holly G ^a,b,c   Diamond, Eli L ^d   Zhang, Baohui ^a   Wright, Alexi A ^a,b   Meyer, Fremonta ^b,c   Maciejewski, Paul K ^a,b,c  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cancer; caregiver; cognitive impairment; end of life; terminal illness; treatment preferences

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; CANCER PATIENT; CANCER SURVIVAL; CAREGIVER; COGNITION; COGNITIVE DEFECT; ETHNIC GROUP; FEMALE; HUMAN; INTENSIVE CARE; INTERVIEW; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH; POSTHUMOUS CARE; SHORT PORTABLE MENTAL STATUS QUESTIONNAIRE; TERMINAL CARE;

AGE DISTRIBUTION; ATTITUDE TO HEALTH; BOSTON; CAREGIVERS; DECISION MAKING; EDUCATIONAL STATUS; FEMALE; HUMANS; MALE; MARITAL STATUS; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NEOPLASMS; PALLIATIVE CARE; PREVALENCE; RISK FACTORS; SEX DISTRIBUTION; SURVIVAL ANALYSIS; SURVIVAL RATE; TERMINAL CARE;

EID: 84875713684     PISSN: 08853924     EISSN: 18736513     Source Type: Journal    
DOI: 10.1016/j.jpainsymman.2012.03.003     Document Type: Article

References (35)

1. M.J. Massie, J. Holland, and E. Glass Delirium in terminally ill cancer patients Am J Psychiatry 140 1983 1048 1050 (Pubitemid 13028678)
2. P.G. Lawlor, B. Gagnon, and I.L. Mancini Occurrence, causes, and outcome of delirium in patients with advanced cancer: a prospective study Arch Intern Med 160 2000 786 794 (Pubitemid 30165239)
3. J. Pereira, J. Hanson, and E. Bruera The frequency and clinical course of cognitive impairment in patients with terminal cancer Cancer 79 1997 835 842 (Pubitemid 27076350)
4. C. Centeno, A. Sanz, and E. Bruera Delirium in advanced cancer patients Palliat Med 18 2004 184 194 (Pubitemid 38771658)
5. M. Klein, T.J. Postma, and M.J. Taphoorn The prognostic value of cognitive functioning in the survival of patients with high-grade glioma Neurology 61 2003 1796 1798 (Pubitemid 38020834)
6. C. Robb, D. Boulware, J. Overcash, and M. Extermann Patterns of care and survival in cancer patients with cognitive impairment Crit Rev Oncol Hematol 74 2010 218 224
7. E.J. Emanuel, and L.L. Emanuel Proxy decision making for incompetent patients. An ethical and empirical analysis JAMA 267 1992 2067 2071
8. D. Potkins, S. Bradley, and J. Shrimanker End of life treatment decisions in people with dementia: carers' views and the factors which influence them Int J Geriatr Psychiatry 15 2000 1005 1008
9. G. Livingston, G. Leavey, and M. Manela Making decisions for people with dementia who lack capacity: qualitative study of family carers in UK BMJ 341 2010 c4184
10. J. Chodosh, D.B. Petitti, and M. Elliott Physician recognition of cognitive impairment: evaluating the need for improvement J Am Geriatr Soc 52 2004 1051 1059 (Pubitemid 38869062)
11. L.C. Hanson, M. Danis, E. Mutran, and N.L. Keenan Impact of patient incompetence on decisions to use or withhold life-sustaining treatment Am J Med 97 1994 235 241
12. A.A. Wright, J.W. Mack, and P.A. Kritek Influence of patients' preferences and treatment site on cancer patients' end-of-life care Cancer 116 2010 4656 4663
13. J.C. Weeks, E.F. Cook, and S.J. O'Day Relationship between cancer patients' predictions of prognosis and their treatment preferences JAMA 279 1998 1709 1714 (Pubitemid 28247301)
14. M. Danis, E. Mutran, and J.M. Garrett A pro-spective study of the impact of patient preferences on life-sustaining treatment and hospital cost Crit Care Med 24 1996 1811 1817 (Pubitemid 26382923)
15. J.W. Mack, M.E. Paulk, K. Viswanath, and H.G. Prigerson Racial disparities in the outcomes of communication on medical care received near death Arch Intern Med 170 2010 1533 1540
16. J.T. Berger, E.G. DeRenzo, and J. Schwartz Surrogate decision making: reconciling ethical theory and clinical practice Ann Intern Med 149 2008 48 53
17. A.A. Wright, B. Zhang, and A. Ray Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment JAMA 300 2008 1665 1673
18. D.A. Karnofsky Determining the extent of the cancer and clinical planning for cure Cancer 22 1968 730 734
19. M.E. Charlson, P. Pompei, K.L. Ales, and C.R. MacKenzie A new method of classifying prognostic comorbidity in longitudinal studies: development and validation J Chronic Dis 40 1987 373 383 (Pubitemid 17055592)
20. E. Pfeiffer A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients J Am Geriatr Soc 23 1975 433 441
21. R.S. Allen, W.E. Haley, B.J. Small, and S.C. McMillan Pain reports by older hospice cancer patients and family caregivers: the role of cognitive functioning Gerontologist 42 2002 507 514 (Pubitemid 34847627)
22. C. D'Angelo, A. Mirijello, and L. Leggio State and trait anxiety and depression in patients with primary brain tumors before and after surgery: 1-year longitudinal study J Neurosurg 108 2008 281 286 (Pubitemid 351213291)
23. T.R. Fried, E.H. Bradley, and V.R. Towle Assessment of patient preferences: integrating treatments and outcomes J Gerontol B Psychol Sci Soc Sci 57 2002 S348 S354
24. The SUPPORT Principal Investigators A controlled trial to improve care for seriously ill hospitalized patients. The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT) JAMA 274 1995 1591 1598
25. E.W. Mebane, R.F. Oman, L.T. Kroonen, and M.K. Goldstein The influence of physician race, age, and gender on physician attitudes toward advance care directives and preferences for end-of-life decision-making J Am Geriatr Soc 47 1999 579 591 (Pubitemid 29215587)
26. C.C. Earle, B.A. Neville, and M.B. Landrum Trends in the aggressiveness of cancer care near the end of life J Clin Oncol 22 2004 315 321 (Pubitemid 41095097)
27. S.M. Moorman, R.M. Hauser, and D. Carr Do older adults know their spouses' end-of-life treatment preferences? Res Aging 31 2009 463 491
28. P.M. Layde, C.A. Beam, and S.K. Broste Surrogates' predictions of seriously ill patients' resuscitation preferences Arch Fam Med 4 1995 518 523
29. A. Fagerlin, P.H. Ditto, J.H. Danks, R.M. Houts, and W.D. Smucker Projection in surrogate decisions about life-sustaining medical treatments Health Psychol 20 2001 166 175 (Pubitemid 32507353)
30. M.A. Marks, and H.R. Arkes Patient and surrogate disagreement in end-of-life decisions: can surrogates accurately predict patients' preferences? Med Decis Making 28 2008 524 531 (Pubitemid 351990001)
31. J.A. Cosgriff, M. Pisani, E.H. Bradley, J.R. O'Leary, and T.R. Fried The association between treatment preferences and trajectories of care at the end-of-life J Gen Intern Med 22 2007 1566 1571 (Pubitemid 47568692)
32. D.I. Shalowitz, E. Garrett-Mayer, and D. Wendler The accuracy of surrogate decision makers: a systematic review Arch Intern Med 166 2006 493 497
33. J. Moye, M.J. Karel, R.J. Gurrera, and A.R. Azar Neuropsychological predictors of decision-making capacity over 9 months in mild-to-moderate dementia J Gen Intern Med 21 2006 78 83
34. O.C. Okonkwo, H.R. Griffith, and J.N. Copeland Medical decision-making capacity in mild cognitive impairment: a 3-year longitudinal study Neurology 71 2008 1474 1480
35. T.R. Fried, P.H. Van Ness, and A.L. Byers Changes in preferences for life-sustaining treatment among older persons with advanced illness J Gen Intern Med 22 2007 495 501 (Pubitemid 46941205)