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Volumn 40, Issue 4, 2013, Pages 514-523

68Ga-DOTA-TOC uptake in neuroendocrine tumour and healthy tissue: Differentiation of physiological uptake and pathological processes in PET/CT

Author keywords

68Ga DOTA TOC; Neuroendocrine tumours; SUVmax

Indexed keywords

1,4,7,10 TETRAAZACYCLO DODECANE N,N',N'',N''' TETRAACETICACID DEXTRO PHENYLALANINE TYROSINE3 OCTREOTIDE GA 68; 1,4,7,10 TETRAAZACYCLO DODECANE N,N',N'',N''' TETRAACETICACID DEXTRO PHENYLALANINE TYROSINE3 OCTREOTIDE Y 90; ANTINEOPLASTIC AGENT; DOTA TATE LU 177; IOMEPROL; MIBG I 131; RADIOPHARMACEUTICAL AGENT; SOMATOSTATIN RECEPTOR; TRACER; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; DRUG DERIVATIVE; GA(III) DOTATOC; GA(III)-DOTATOC; OCTREOTIDE; ORGANOMETALLIC COMPOUND;

EID: 84875711877     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-012-2309-3     Document Type: Article
Times cited : (92)

References (29)
  • 1
    • 0034924612 scopus 로고    scopus 로고
    • Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands
    • 11504080 10.1007/s002590100541 1:CAS:528:DC%2BD3MXkvVWltL0%3D
    • Reubi JC, Waser B, Schaer JC, Laissue JA. Somatostatin receptor sst1-sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands. Eur J Nucl Med. 2001;28:836-46.
    • (2001) Eur J Nucl Med. , vol.28 , pp. 836-846
    • Reubi, J.C.1    Waser, B.2    Schaer, J.C.3    Laissue, J.A.4
  • 2
    • 0034033495 scopus 로고    scopus 로고
    • Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use
    • 10774879 10.1007/s002590050034 1:CAS:528:DC%2BD3cXhsVWns7w%3D
    • Reubi JC, Schaer JC, Waser B, Wenger S, Heppeler A, Schmitt JS, et al. Affinity profiles for human somatostatin receptor subtypes SST1-SST5 of somatostatin radiotracers selected for scintigraphic and radiotherapeutic use. Eur J Nucl Med. 2000;27:273-82.
    • (2000) Eur J Nucl Med , vol.27 , pp. 273-282
    • Reubi, J.C.1    Schaer, J.C.2    Waser, B.3    Wenger, S.4    Heppeler, A.5    Schmitt, J.S.6
  • 3
    • 25144507525 scopus 로고    scopus 로고
    • Value of 111In-DOTA-lanreotide and 111In-DOTA-DPhe1-Tyr3-octreotide in differentiated thyroid cancer: Results of in vitro binding studies and in vivo comparison with 18F-FDG PET
    • 15909194 10.1007/s00259-005-1820-1 1:CAS:528:DC%2BD2MXhtVent7%2FF
    • Rodrigues M, Traub-Weidinger T, Leimer M, Li S, Andreae F, Angelberger P, et al. Value of 111In-DOTA-lanreotide and 111In-DOTA-DPhe1-Tyr3-octreotide in differentiated thyroid cancer: results of in vitro binding studies and in vivo comparison with 18F-FDG PET. Eur J Nucl Med Mol Imaging. 2005;32:1144-51.
    • (2005) Eur J Nucl Med Mol Imaging , vol.32 , pp. 1144-1151
    • Rodrigues, M.1    Traub-Weidinger, T.2    Leimer, M.3    Li, S.4    Andreae, F.5    Angelberger, P.6
  • 4
    • 0032587874 scopus 로고    scopus 로고
    • Comparison of 111In-DOTA-Tyr3-octreotide and 111In-DTPA-octreotide in the same patients: Biodistribution, kinetics, organ and tumor uptake
    • 10319747 1:CAS:528:DyaK1MXjsVamurw%3D
    • Kwekkeboom DJ, Kooij PP, Bakker WH, Mäcke HR, Krenning EP. Comparison of 111In-DOTA-Tyr3-octreotide and 111In-DTPA-octreotide in the same patients: biodistribution, kinetics, organ and tumor uptake. J Nucl Med. 1999;40:762-7.
    • (1999) J Nucl Med , vol.40 , pp. 762-767
    • Kwekkeboom, D.J.1    Kooij, P.P.2    Bakker, W.H.3    Mäcke, H.R.4    Krenning, E.P.5
  • 5
    • 38449118147 scopus 로고    scopus 로고
    • Receptor PET/CT imaging of neuroendocrine tumors
    • 18019630 10.1007/978-3-540-31203-1-18 1:STN:280:DC%2BD2snos1KgtA%3D%3D
    • Baum RP, Prasad V, Hommann M, Hörsch D. Receptor PET/CT imaging of neuroendocrine tumors. Recent Results Cancer Res. 2008;170:225-42.
    • (2008) Recent Results Cancer Res. , vol.170 , pp. 225-242
    • Baum, R.P.1    Prasad, V.2    Hommann, M.3    Hörsch, D.4
  • 6
    • 34248529824 scopus 로고    scopus 로고
    • 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: Comparison with somatostatin receptor scintigraphy and CT
    • 17401086 10.2967/jnumed.106.035667 1:CAS:528:DC%2BD2sXhtVert7jF
    • Gabriel M, Decristoforo C, Kendler D, Dobrozemsky G, Heute D, Uprimny C, et al. 68Ga-DOTA-Tyr3-octreotide PET in neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and CT. J Nucl Med. 2007;48:508-18.
    • (2007) J Nucl Med , vol.48 , pp. 508-518
    • Gabriel, M.1    Decristoforo, C.2    Kendler, D.3    Dobrozemsky, G.4    Heute, D.5    Uprimny, C.6
  • 7
    • 68249154749 scopus 로고    scopus 로고
    • Bone metastases in patients with neuroendocrine tumor: 68Ga-DOTA-Tyr3-octreotide PET in comparison to CT and bone scintigraphy
    • 19617343 10.2967/jnumed.108.060236
    • Putzer D, Gabriel M, Henninger B, Kendler D, Uprimny C, Dobrozemsky G, et al. Bone metastases in patients with neuroendocrine tumor: 68Ga-DOTA-Tyr3- octreotide PET in comparison to CT and bone scintigraphy. J Nucl Med. 2009;50:1214-21.
    • (2009) J Nucl Med , vol.50 , pp. 1214-1221
    • Putzer, D.1    Gabriel, M.2    Henninger, B.3    Kendler, D.4    Uprimny, C.5    Dobrozemsky, G.6
  • 8
    • 79958046632 scopus 로고    scopus 로고
    • 68Ga-DOTATOC PET/CT and somatostatin receptor (sst1-sst5) expression in normal human tissue: Correlation of sst2 mRNA and SUVmax
    • 21369945 10.1007/s00259-011-1760-x 1:CAS:528:DC%2BC3MXmvVais70%3D
    • Boy C, Heusner TA, Poeppel TD, Redmann-Bischofs A, Unger N, Jentzen W, et al. 68Ga-DOTATOC PET/CT and somatostatin receptor (sst1-sst5) expression in normal human tissue: correlation of sst2 mRNA and SUVmax. Eur J Nucl Med Mol Imaging. 2011;38:1224-36.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 1224-1236
    • Boy, C.1    Heusner, T.A.2    Poeppel, T.D.3    Redmann-Bischofs, A.4    Unger, N.5    Jentzen, W.6
  • 9
    • 34848920415 scopus 로고    scopus 로고
    • A fully automated synthesis for the preparation of 68Ga-labelled peptides
    • 17901771 10.1097/MNM.0b013e3282f1753d 1:CAS:528:DC%2BD2sXhtFSnt7rL
    • Decristoforo C, Knopp R, von Guggenberg E, Rupprich M, Dreger T, Hess A, et al. A fully automated synthesis for the preparation of 68Ga-labelled peptides. Nucl Med Commun. 2007;28:870-5.
    • (2007) Nucl Med Commun , vol.28 , pp. 870-875
    • Decristoforo, C.1    Knopp, R.2    Von Guggenberg, E.3    Rupprich, M.4    Dreger, T.5    Hess, A.6
  • 10
    • 77952503305 scopus 로고    scopus 로고
    • Biodistribution of the Ga-68 labeled somatostatin analogue DOTA-NOC in patients with neuroendocrine tumors: Characterization of uptake in normal organs and tumor lesions
    • 20168287 1:STN:280:DC%2BC3c7hvVKrtw%3D%3D
    • Prasad V, Baum RP. Biodistribution of the Ga-68 labeled somatostatin analogue DOTA-NOC in patients with neuroendocrine tumors: characterization of uptake in normal organs and tumor lesions. Q J Nucl Med Mol Imaging. 2010;54:61-7.
    • (2010) Q J Nucl Med Mol Imaging , vol.54 , pp. 61-67
    • Prasad, V.1    Baum, R.P.2
  • 11
    • 83755171298 scopus 로고    scopus 로고
    • 68Ga-DOTATOC versus 68Ga-DOTATATE PET/CT in functional imaging of neuroendocrine tumors
    • 22072704 10.2967/jnumed.111.091165 1:CAS:528:DC%2BC38Xht1Skur4%3D
    • Poeppel TD, Binse I, Petersenn S, Lahner H, Schott M, Antoch G, et al. 68Ga-DOTATOC versus 68Ga-DOTATATE PET/CT in functional imaging of neuroendocrine tumors. J Nucl Med. 2011;52:1864-70.
    • (2011) J Nucl Med , vol.52 , pp. 1864-1870
    • Poeppel, T.D.1    Binse, I.2    Petersenn, S.3    Lahner, H.4    Schott, M.5    Antoch, G.6
  • 12
    • 0027517429 scopus 로고
    • Somatostatin receptor scintigraphy with [111In-DTPA-D-Phe1]- and [123I-Tyr3]-octreotide: The Rotterdam experience with more than 1000 patients
    • 8404961 10.1007/BF00181765 1:STN:280:DyaK2c%2FgvFWjug%3D%3D
    • Krenning EP, Kwekkeboom DJ, Bakker WH, Breeman WA, Kooij PP, Oei HY, et al. Somatostatin receptor scintigraphy with [111In-DTPA-D-Phe1]- and [123I-Tyr3]-octreotide: the Rotterdam experience with more than 1000 patients. Eur J Nucl Med. 1993;20:716-31.
    • (1993) Eur J Nucl Med , vol.20 , pp. 716-731
    • Krenning, E.P.1    Kwekkeboom, D.J.2    Bakker, W.H.3    Breeman, W.A.4    Kooij, P.P.5    Oei, H.Y.6
  • 13
    • 0036301683 scopus 로고    scopus 로고
    • Detection of neuroendocrine tumors: 99mTc-P829 scintigraphy compared with 111In-pentetreotide scintigraphy
    • 12097458 1:CAS:528:DC%2BD38XlvVKgsbY%3D
    • Lebtahi R, Le Cloirec J, Houzard C, Daou D, Sobhani I, Sassolas G, et al. Detection of neuroendocrine tumors: 99mTc-P829 scintigraphy compared with 111In-pentetreotide scintigraphy. J Nucl Med. 2002;43:889-95.
    • (2002) J Nucl Med , vol.43 , pp. 889-895
    • Lebtahi, R.1    Le Cloirec, J.2    Houzard, C.3    Daou, D.4    Sobhani, I.5    Sassolas, G.6
  • 14
    • 0031910371 scopus 로고    scopus 로고
    • Limited value of fluorine-18 fluorodeoxyglucose positron emission tomography for the imaging of neuroendocrine tumours
    • 9396878 10.1007/s002590050197 1:CAS:528:DyaK2sXnvVGru7o%3D
    • Adams S, Baum R, Rink T, Schumm-Dräger PM, Usadel KH, Hör G. Limited value of fluorine-18 fluorodeoxyglucose positron emission tomography for the imaging of neuroendocrine tumours. Eur J Nucl Med. 1998;25:79-83.
    • (1998) Eur J Nucl Med , vol.25 , pp. 79-83
    • Adams, S.1    Baum, R.2    Rink, T.3    Schumm-Dräger, P.M.4    Usadel, K.H.5    Hör, G.6
  • 15
    • 77952519078 scopus 로고    scopus 로고
    • Comparison of (68)Ga-DOTA-Tyr(3)-octreotide and (18)F-fluoro-L- dihydroxyphenylalanine positron emission tomography in neuroendocrine tumor patients
    • 20168288 1:STN:280:DC%2BC3c7hvVKrtA%3D%3D
    • Putzer D, Gabriel M, Kendler D, Henninger B, Knoflach M, Kroiss A, et al. Comparison of (68)Ga-DOTA-Tyr(3)-octreotide and (18)F-fluoro-L- dihydroxyphenylalanine positron emission tomography in neuroendocrine tumor patients. Q J Nucl Med Mol Imaging. 2010;54:68-75.
    • (2010) Q J Nucl Med Mol Imaging , vol.54 , pp. 68-75
    • Putzer, D.1    Gabriel, M.2    Kendler, D.3    Henninger, B.4    Knoflach, M.5    Kroiss, A.6
  • 16
    • 77952508806 scopus 로고    scopus 로고
    • Comparison of positron emission tomography with [(18)F]FDG and [(68)Ga]DOTATOC in recurrent differentiated thyroid cancer: Preliminary data
    • 20168289 1:STN:280:DC%2BC3c7hvVKrtQ%3D%3D
    • Middendorp M, Selkinski I, Happel C, Kranert WT, Grünwald F. Comparison of positron emission tomography with [(18)F]FDG and [(68)Ga]DOTATOC in recurrent differentiated thyroid cancer: preliminary data. Q J Nucl Med Mol Imaging. 2010;54:76-83.
    • (2010) Q J Nucl Med Mol Imaging , vol.54 , pp. 76-83
    • Middendorp, M.1    Selkinski, I.2    Happel, C.3    Kranert, W.T.4    Grünwald, F.5
  • 17
    • 79953717721 scopus 로고    scopus 로고
    • Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr 3-octreotide positron emission tomography and 123I- metaiodobenzylguanidine
    • 21279352 10.1007/s00259-010-1720-x 1:CAS:528:DC%2BC3MXkt1WrsL0%3D
    • Kroiss A, Putzer D, Uprimny C, Decristoforo C, Gabriel M, Santner W, et al. Functional imaging in phaeochromocytoma and neuroblastoma with 68Ga-DOTA-Tyr 3-octreotide positron emission tomography and 123I-metaiodobenzylguanidine. Eur J Nucl Med Mol Imaging. 2011;38:865-73.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 865-873
    • Kroiss, A.1    Putzer, D.2    Uprimny, C.3    Decristoforo, C.4    Gabriel, M.5    Santner, W.6
  • 18
    • 80255138228 scopus 로고    scopus 로고
    • Focal uptake of 68Ga-DOTATOC in the pancreas: Pathological or physiological correlate in patients with neuroendocrine tumours?
    • 21792572 10.1007/s00259-011-1875-0 1:CAS:528:DC%2BC3MXht12js73M
    • Al-Ibraheem A, Bundschuh RA, Notni J, Buck A, Winter A, Wester HJ, et al. Focal uptake of 68Ga-DOTATOC in the pancreas: pathological or physiological correlate in patients with neuroendocrine tumours? Eur J Nucl Med Mol Imaging. 2011;38:2005-13.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 2005-2013
    • Al-Ibraheem, A.1    Bundschuh, R.A.2    Notni, J.3    Buck, A.4    Winter, A.5    Wester, H.J.6
  • 19
    • 84858114170 scopus 로고    scopus 로고
    • Normal uptake of 68Ga-DOTA-TOC by the pancreas uncinate process mimicking malignancy at somatostatin receptor PET
    • 22391705 10.1097/RLU.0b013e3182485110
    • Jacobsson H, Larsson P, Jonsson C, Jussing E, Grybäck P. Normal uptake of 68Ga-DOTA-TOC by the pancreas uncinate process mimicking malignancy at somatostatin receptor PET. Clin Nucl Med. 2012;37:362-5.
    • (2012) Clin Nucl Med , vol.37 , pp. 362-365
    • Jacobsson, H.1    Larsson, P.2    Jonsson, C.3    Jussing, E.4    Grybäck, P.5
  • 20
    • 57249095880 scopus 로고    scopus 로고
    • Correlation of immunohistopathological expression of somatostatin receptor 2 with standardised uptake values in 68Ga-DOTATOC PET/CT
    • 18807033 10.1007/s00259-008-0944-5 1:CAS:528:DC%2BD1cXhsVGqurzJ
    • Miederer M, Seidl S, Buck A, Scheidhauer K, Wester HJ, Schwaiger M, et al. Correlation of immunohistopathological expression of somatostatin receptor 2 with standardised uptake values in 68Ga-DOTATOC PET/CT. Eur J Nucl Med Mol Imaging. 2009;36:48-52.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 48-52
    • Miederer, M.1    Seidl, S.2    Buck, A.3    Scheidhauer, K.4    Wester, H.J.5    Schwaiger, M.6
  • 21
    • 84865471278 scopus 로고    scopus 로고
    • Comparison of (68)Ga-DOTATATE and (68)Ga-DOTANOC PET/CT imaging in the same patient group with neuroendocrine tumours
    • 22526963 10.1007/s00259-012-2123-y
    • Kabasakal L, Demirci E, Ocak M, Decristoforo C, Araman A, Ozsoy Y, et al. Comparison of (68)Ga-DOTATATE and (68)Ga-DOTANOC PET/CT imaging in the same patient group with neuroendocrine tumours. Eur J Nucl Med Mol Imaging. 2012;39:1271-7.
    • (2012) Eur J Nucl Med Mol Imaging , vol.39 , pp. 1271-1277
    • Kabasakal, L.1    Demirci, E.2    Ocak, M.3    Decristoforo, C.4    Araman, A.5    Ozsoy, Y.6
  • 22
    • 6944235697 scopus 로고    scopus 로고
    • Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: A simulation study
    • 15347719
    • Boellaard R, Krak NC, Hoekstra OS, Lammertsma AA. Effects of noise, image resolution, and ROI definition on the accuracy of standard uptake values: a simulation study. J Nucl Med. 2004;45:1519-27.
    • (2004) J Nucl Med , vol.45 , pp. 1519-1527
    • Boellaard, R.1    Krak, N.C.2    Hoekstra, O.S.3    Lammertsma, A.A.4
  • 23
    • 17844376249 scopus 로고    scopus 로고
    • Influence of reconstruction iterations on 18F-FDG PET/CT standardized uptake values
    • 15750154
    • Jaskowiak CJ, Bianco JA, Perlman SB, Fine JP. Influence of reconstruction iterations on 18F-FDG PET/CT standardized uptake values. J Nucl Med. 2005;46:424-8.
    • (2005) J Nucl Med , vol.46 , pp. 424-428
    • Jaskowiak, C.J.1    Bianco, J.A.2    Perlman, S.B.3    Fine, J.P.4
  • 24
    • 79952792137 scopus 로고    scopus 로고
    • Improvement in lesion detection with whole-body oncologic time-of-flight PET
    • 21321265 10.2967/jnumed.110.080382
    • El Fakhri G, Surti S, Trott CM, Scheuermann J, Karp JS. Improvement in lesion detection with whole-body oncologic time-of-flight PET. J Nucl Med. 2011;52:347-53.
    • (2011) J Nucl Med , vol.52 , pp. 347-353
    • El Fakhri, G.1    Surti, S.2    Trott, C.M.3    Scheuermann, J.4    Karp, J.S.5
  • 25
    • 75749085816 scopus 로고    scopus 로고
    • An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging
    • 20080882 10.2967/jnumed.109.068098
    • Lois C, Jakoby BW, Long MJ, Hubner KF, Barker DW, Casey ME, et al. An assessment of the impact of incorporating time-of-flight information into clinical PET/CT imaging. J Nucl Med. 2010;51:237-45.
    • (2010) J Nucl Med , vol.51 , pp. 237-245
    • Lois, C.1    Jakoby, B.W.2    Long, M.J.3    Hubner, K.F.4    Barker, D.W.5    Casey, M.E.6
  • 26
    • 77950297123 scopus 로고    scopus 로고
    • In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours - Impact of peptide mass
    • 20346866 10.1016/j.nucmedbio.2009.11.008 1:CAS:528:DC%2BC3cXjvFKkt7s%3D
    • Velikyan I, Sundin A, Eriksson B, Lundqvist H, Sörensen J, Bergström M, et al. In vivo binding of [68Ga]-DOTATOC to somatostatin receptors in neuroendocrine tumours - impact of peptide mass. Nucl Med Biol. 2010;37:265-75.
    • (2010) Nucl Med Biol , vol.37 , pp. 265-275
    • Velikyan, I.1    Sundin, A.2    Eriksson, B.3    Lundqvist, H.4    Sörensen, J.5    Bergström, M.6
  • 27
    • 77957096107 scopus 로고    scopus 로고
    • 68Ga-DOTATATE PET/CT for the early prediction of response to somatostatin receptor-mediated radionuclide therapy in patients with well-differentiated neuroendocrine tumors
    • 20720050 10.2967/jnumed.110.075002 1:CAS:528:DC%2BC3cXht1ejsLrJ
    • Haug AR, Auernhammer CJ, Wängler B, Schmidt GP, Uebleis C, Göke B, et al. 68Ga-DOTATATE PET/CT for the early prediction of response to somatostatin receptor-mediated radionuclide therapy in patients with well-differentiated neuroendocrine tumors. J Nucl Med. 2010;51:1349-56.
    • (2010) J Nucl Med , vol.51 , pp. 1349-1356
    • Haug, A.R.1    Auernhammer, C.J.2    Wängler, B.3    Schmidt, G.P.4    Uebleis, C.5    Göke, B.6
  • 28
    • 77950576566 scopus 로고    scopus 로고
    • Experimental investigation of factors affecting the absolute recovery coefficients in iodine-124 PET lesion imaging
    • 20360631 10.1088/0031-9155/55/8/016
    • Jentzen W. Experimental investigation of factors affecting the absolute recovery coefficients in iodine-124 PET lesion imaging. Phys Med Biol. 2010;55:2365-98.
    • (2010) Phys Med Biol , vol.55 , pp. 2365-2398
    • Jentzen, W.1
  • 29
    • 84858737611 scopus 로고    scopus 로고
    • The tumour sink effect on the biodistribution of 68Ga-DOTA-octreotate: Implications for peptide receptor radionuclide therapy
    • 21932117 10.1007/s00259-011-1937-3 1:CAS:528:DC%2BC3MXhsFOgt7nF
    • Beauregard JM, Hofman MS, Kong G, Hicks RJ. The tumour sink effect on the biodistribution of 68Ga-DOTA-octreotate: implications for peptide receptor radionuclide therapy. Eur J Nucl Med Mol Imaging. 2012;39:50-6.
    • (2012) Eur J Nucl Med Mol Imaging , vol.39 , pp. 50-56
    • Beauregard, J.M.1    Hofman, M.S.2    Kong, G.3    Hicks, R.J.4


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