Pro-inflammatory and pathogenic properties of Annexin-A1: The whole is greater than the sum of its parts

Biochemical Pharmacology

Volumn 85, Issue 9, 2013, Pages 1213-1218

  D'Acquisto, Fulvio ^a   Piras, Giuseppa ^a   Rattazzi, Lorenza ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Annexin A1; Autoimmunity; Cancer; Formyl peptide agonist; Inflammation

Indexed keywords

INTERSTITIAL COLLAGENASE; LIPOCORTIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE A2; PHOSPHOLIPASE D;

ANTIINFLAMMATORY ACTIVITY; AUTOIMMUNITY; BREAST CANCER; CYSTIC FIBROSIS; DESENSITIZATION; FIBROSING ALVEOLITIS; HAIRY CELL LEUKEMIA; HUMAN; LIVER SINUSOID; LYMPHOPROLIFERATIVE DISEASE; MELANOMA; NONHUMAN; PANCYTOPENIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN HOMEOSTASIS; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SPLENOMEGALY; SQUAMOUS CELL CARCINOMA; SYSTEMIC LUPUS ERYTHEMATOSUS; ULCERATIVE COLITIS;

EID: 84875699579     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2013.02.011     Document Type: Note

References (78)

1. G.J. Blackwell, R. Carnuccio, M. Di Rosa, R.J. Flower, L. Parente, and P. Persico Macrocortin: a polypeptide causing the anti-phospholipase effect of glucocorticoids Nature 287 1980 147 149
2. G.J. Blackwell, R. Carnuccio, M. Di Rosa, R.J. Flower, C.S. Langham, and L. Parente Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat Br J Pharmacol 76 1982 185 194
3. J.R. Vane Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs Nat: New Biol 231 1971 232 235
4. G.J. Blackwell, and R.J. Flower Glucocorticoids, lungs and prostaglandins Bull Eur Physiopathol Respir 17 1981 595 607
5. V. Gerke, and S.E. Moss Annexins: from structure to function Physiol Rev 82 2002 331 371
6. U. Rescher, and V. Gerke Annexins - unique membrane binding proteins with diverse functions J Cell Sci 117 2004 2631 2639
7. M.V. Dorovkov, and A.G. Ryazanov Phosphorylation of annexin I by TRPM7 channel-kinase J Biol Chem 279 2004 50643 50646
8. F. Goulet, K.G. Moore, and A.C. Sartorelli Glycosylation of annexin I and annexin II Biochem Biophys Res Commun 188 1992 554 558
9. P. Bist, S.C. Leow, Q.H. Phua, S. Shu, Q. Zhuang, and W.T. Loh Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappaB: implication in breast cancer metastasis Oncogene 30 2011 3174 3185
10. P.O. Cover, F. Baanah-Jones, C.D. John, and J.C. Buckingham Annexin 1 (lipocortin 1) mimics inhibitory effects of glucocorticoids on testosterone secretion and enhances effects of interleukin-1beta Endocrine 18 2002 33 39
11. M.D. Black, F. Carey, A.R. Crossman, J.K. Relton, and N.J. Rothwell Lipocortin-1 inhibits NMDA receptor-mediated neuronal damage in the striatum of the rat Brain Res 585 1992 135 140
12. M. Perretti, S.J. Getting, E. Solito, P.M. Murphy, and J.L. Gao Involvement of the receptor for formylated peptides in the in vivo anti-migratory actions of annexin 1 and its mimetics Am J Pathol 158 2001 1969 1973
13. S. Ernst, C. Lange, A. Wilbers, V. Goebeler, V. Gerke, and U. Rescher An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family J Immunol 172 2004 7669 7676
14. C. Lange, D.J. Starrett, J. Goetsch, V. Gerke, and U. Rescher Transcriptional profiling of human monocytes reveals complex changes in the expression pattern of inflammation-related genes in response to the annexin A1-derived peptide Ac1-25 J Leukoc Biol 82 2007 1592 1604
15. R.P. Hayhoe, A.M. Kamal, E. Solito, R.J. Flower, D. Cooper, and M. Perretti Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement Blood 107 2006 2123 2130
16. A.M. Kamal, R.P. Hayhoe, A. Paramasivam, D. Cooper, R.J. Flower, and E. Solito Antiflammin-2 activates the human formyl-peptide receptor like 1 Sci World J 6 2006 1375 1384
17. J.J. Moreno Antiflammin-2 prevents HL-60 adhesion to endothelial cells and prostanoid production induced by lipopolysaccharides J Pharmacol Exp Ther 296 2001 884 889
18. A. Walther, K. Riehemann, and V. Gerke A novel ligand of the formyl peptide receptor: annexin I regulates neutrophil extravasation by interacting with the FPR Mol Cell 5 2000 831 840
19. M. Perretti, N. Chiang, M. La, I.M. Fierro, S. Marullo, and S.J. Getting Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor Nat Med 8 2002 1296 1302
20. Y. Le, J.M. Wang, X. Liu, Y. Kong, X. Hou, and L. Ruan Biologically active peptides interacting with the G protein-coupled formylpeptide receptor Protein Pept Lett 14 2007 846 853
21. R. Hannon, J.D. Croxtall, S.J. Getting, F. Roviezzo, S. Yona, and M.J. Paul-Clark Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse FASEB J 17 2003 253 255
22. M. Perretti, and F. D'Acquisto Annexin A1 and glucocorticoids as effectors of the resolution of inflammation Nat Rev Immunol 9 2009 62 70
23. A.S. Damazo, S. Yona, F. D'Acquisto, R.J. Flower, S.M. Oliani, and M. Perretti Critical protective role for annexin 1 gene expression in the endotoxemic murine microcirculation Am J Pathol 166 2005 1607 1617
24. T.S. Gastardelo, A.S. Damazo, J. Dalli, R.J. Flower, M. Perretti, and S.M. Oliani Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation Am J Pathol 174 2009 177 183
25. A.S. Damazo, S. Yona, R.J. Flower, M. Perretti, and S.M. Oliani Spatial and temporal profiles for anti-inflammatory gene expression in leukocytes during a resolving model of peritonitis J Immunol 176 2006 4410 4418
26. F. Zhu, C. Xu, Z. Jiang, M. Jin, L. Wang, and S. Zeng Nuclear localization of annexin A1 correlates with advanced disease and peritoneal dissemination in patients with gastric carcinoma Anat Rec (Hoboken) 293 2010 1310 1314
27. Z. Zhang, L. Huang, W. Zhao, and B. Rigas Annexin 1 induced by anti-inflammatory drugs binds to NF-kappaB and inhibits its activation: anticancer effects in vitro and in vivo Cancer Res 70 2010 2379 2388
28. N. Chiang, C.N. Serhan, S.E. Dahlen, J.M. Drazen, D.W. Hay, and G.E. Rovati The lipoxin receptor ALX: potent ligand-specific and stereoselective actions in vivo Pharmacol Rev 58 2006 463 487
29. R.D. Ye, F. Boulay, J.M. Wang, C. Dahlgren, C. Gerard, and M. Parmentier International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family Pharmacol Rev 61 2009 119 161
30. P. Hofman Molecular regulation of neutrophil apoptosis and potential targets for therapeutic strategy against the inflammatory process Curr Drug Targets Inflamm Allergy 3 2004 1 9
31. G. Gorelik, and B. Richardson Key role of ERK pathway signaling in lupus Autoimmunity 43 2010 17 22
32. A.J. Whitmarsh, and R.J. Davis Analyzing mitogen-activated protein kinase (MAPK) activities in T cells Curr Protoc Immunol 2004 [Chapter 11, Unit 11.8]
33. E. Solito, A. Kamal, F. Russo-Marie, J.C. Buckingham, S. Marullo, and M. Perretti A novel calcium-dependent proapoptotic effect of annexin 1 on human neutrophils FASEB J 17 2003 1544 1546
34. P. Maderna, S. Yona, M. Perretti, and C. Godson Modulation of phagocytosis of apoptotic neutrophils by supernatant from dexamethasone-treated macrophages and annexin-derived peptide Ac(2-26) J Immunol 174 2005 3727 3733
35. K.E. Blume, S. Soeroes, H. Keppeler, S. Stevanovic, D. Kretschmer, and M. Rautenberg Cleavage of annexin A1 by ADAM10 during secondary necrosis generates a monocytic "find-me" signal J Immunol 188 2012 135 145
36. K.E. Blume, S. Soeroes, M. Waibel, H. Keppeler, S. Wesselborg, and M. Herrmann Cell surface externalization of annexin A1 as a failsafe mechanism preventing inflammatory responses during secondary necrosis J Immunol 183 2009 8138 8147
37. J.F. Swisher, N. Burton, S.M. Bacot, S.N. Vogel, and G.M. Feldman Annexin A2 tetramer activates human and murine macrophages through TLR4 Blood 115 2010 549 558
38. L.Y. Chen, and Z.K. Pan Synergistic activation of leukocytes by bacterial chemoattractants: potential drug targets Endocr Metab Immune Disord Drug Targets 9 2009 361 370
39. F. D'Acquisto On the adaptive nature of annexin-A1 Curr Opin Pharmacol 9 2009 521 528
40. F. D'Acquisto, N. Paschalidis, A.L. Sampaio, A. Merghani, R.J. Flower, and M. Perretti T cell activation and increased Th2 lineage commitment in Annexin-1-deficient T cells Eur J Immunol 37 2007 3131 3142
41. F. D'Acquisto, A. Merghani, E. Lecona, G. Rosignoli, K. Raza, and C.D. Buckley Annexin-1 modulates T-cell activation and differentiation Blood 109 2007 1095 1102
42. N. Paschalidis, A. Huggins, N.J. Rowbotham, A.L. Furmanski, T. Crompton, and R.J. Flower Role of endogenous annexin-A1 in the regulation of thymocyte positive and negative selection Cell Cycle 9 2010 784 793
43. K. Hess, Y. Yang, S. Golech, A. Sharov, K.G. Becker, and N.P. Weng Kinetic assessment of general gene expression changes during human naive CD4+ T cell activation Int Immunol 16 2004 1711 1721
44. K. Liu, Y. Li, V. Prabhu, L. Young, K.G. Becker, and P.J. Munson Augmentation in expression of activation-induced genes differentiates memory from naive CD4+ T cells and is a molecular mechanism for enhanced cellular response of memory CD4+ T cells J Immunol 166 2001 7335 7344
45. A. Huggins, N. Paschalidis, R.J. Flower, M. Perretti, and F. D'Acquisto Annexin-1-deficient dendritic cells acquire a mature phenotype during differentiation FASEB J 23 2009 985 996
46. C.E. Tagoe, N. Marjanovic, J.Y. Park, E.S. Chan, A.M. Abeles, and M. Attur Annexin-1 mediates TNF-alpha-stimulated matrix metalloproteinase secretion from rheumatoid arthritis synovial fibroblasts J Immunol 181 2008 2813 2820
47. S.L. Williams, I.R. Milne, C.J. Bagley, J.R. Gamble, M.A. Vadas, and S.M. Pitson A proinflammatory role for proteolytically cleaved annexin A1 in neutrophil transendothelial migration J Immunol 185 2010 3057 3063
48. J.H. Kwon, J.H. Lee, K.S. Kim, Y.W. Chung, and I.Y. Kim Regulation of cytosolic phospholipase A2 phosphorylation by proteolytic cleavage of annexin A1 in activated mast cells J Immunol 188 2012 5665 5673
49. Y.W. Chung, H.Y. Oh, J.Y. Kim, J.H. Kim, and I.Y. Kim Allergen-induced proteolytic cleavage of annexin-1 and activation of cytosolic phospholipase A2 in the lungs of a mouse model of asthma Proteomics 4 2004 3328 3334
50. F.H. Tsao, K.C. Meyer, X. Chen, N.S. Rosenthal, and J. Hu Degradation of annexin I in bronchoalveolar lavage fluid from patients with cystic fibrosis Am J Respir Cell Mol Biol 18 1998 120 128
51. F.H. Tsao, Z. Xiang, A. Abbasi, and K.C. Meyer Neutrophil necrosis and annexin 1 degradation associated with airway inflammation in lung transplant recipients with cystic fibrosis BMC Pulm Med 12 2012 44
52. J. Dalli, G. Rosignoli, R.P. Hayhoe, A. Edelman, and M. Perretti CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway Am J Pathol 177 2010 176 186
53. N. Bensalem, A.P. Ventura, B. Vallee, J. Lipecka, D. Tondelier, and N. Davezac Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients Mol Cell Proteomics 4 2005 1591 1601
54. N. Vergnolle, P. Pages, R. Guimbaud, S. Chaussade, L. Bueno, and J. Escourrou Annexin 1 is secreted in situ during ulcerative colitis in humans Inflamm Bowel Dis 10 2004 584 592
55. T.R. Stevens, S.F. Smith, and D.S. Rampton Antibodies to human recombinant lipocortin-I in inflammatory bowel disease Clin Sci (Lond) 84 1993 381 386
56. K. Kurosu, Y. Takiguchi, O. Okada, N. Yumoto, S. Sakao, and Y. Tada Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis J Immunol 181 2008 756 767
57. N.J. Goulding, M.R. Podgorski, N.D. Hall, R.J. Flower, J.L. Browning, and R.B. Pepinsky Autoantibodies to recombinant lipocortin-1 in rheumatoid arthritis and systemic lupus erythematosus Ann Rheum Dis 48 1989 843 850
58. W. Pruzanski, N.J. Goulding, R.J. Flower, D.D. Gladman, M.B. Urowitz, and P.J. Goodman Circulating group II phospholipase A2 activity and antilipocortin antibodies in systemic lupus erythematosus. Correlative study with disease activity J Rheumatol 21 1994 252 257
59. C.C. Kretz, M. Norpo, L. Abeler-Dorner, B. Linke, M. Haust, and L. Edler Anti-annexin 1 antibodies: a new diagnostic marker in the serum of patients with discoid lupus erythematosus Exp Dermatol 19 2010 919 921
60. C. Bagnato, J. Thumar, V. Mayya, S.I. Hwang, H. Zebroski, and K.P. Claffey Proteomics analysis of human coronary atherosclerotic plaque: a feasibility study of direct tissue proteomics by liquid chromatography and tandem mass spectrometry Mol Cell Proteomics 6 2007 1088 1102
61. B.L. Cheuk, and S.W. Cheng Annexin A1 expression in atherosclerotic carotid plaques and its relationship with plaque characteristics Eur J Vasc Endovasc Surg 41 2011 364 371
62. L.E. Viiri, L.E. Full, T.J. Navin, S. Begum, A. Didangelos, and N. Astola Smooth muscle cells in human atherosclerosis: proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease J Mol Cell Cardiol 2012
63. B. Falini, E. Tiacci, A. Liso, K. Basso, E. Sabattini, and R. Pacini Simple diagnostic assay for hairy cell leukaemia by immunocytochemical detection of annexin A1 (ANXA1) Lancet 363 2004 1869 1870
64. K. Johrens, H. Stein, and I. Anagnostopoulos T-bet transcription factor detection facilitates the diagnosis of minimal hairy cell leukemia infiltrates in bone marrow trephines Am J Surg Pathol 31 2007 1181 1185
65. L. Spurr, S. Nadkarni, M. Pederzoli-Ribeil, N.J. Goulding, M. Perretti, and F. D'Acquisto Comparative analysis of Annexin A1-formyl peptide receptor 2/ALX expression in human leukocyte subsets Int Immunopharmacol 11 2011 55 66
66. C. Protzel, M. Richter, M. Poetsch, C. Kakies, U. Zimmermann, and C. Woenckhaus The role of annexins I, II and IV in tumor development, progression and metastasis of human penile squamous cell carcinomas World J Urol 29 2011 393 398
67. C.K. Yom, W. Han, S.W. Kim, H.S. Kim, H.C. Shin, and J.N. Chang Clinical significance of annexin A1 expression in breast cancer J Breast Cancer 14 2011 262 268
68. X.F. Bai, X.G. Ni, P. Zhao, S.M. Liu, H.X. Wang, and B. Guo Overexpression of annexin 1 in pancreatic cancer and its clinical significance World J Gastroenterol 10 2004 1466 1470
69. J.S. Kang, B.F. Calvo, S.J. Maygarden, L.S. Caskey, J.L. Mohler, and D.K. Ornstein Dysregulation of annexin I protein expression in high-grade prostatic intraepithelial neoplasia and prostate cancer Clin Cancer Res 8 2002 117 123
70. H. Kang, J. Ko, and S.W. Jang The role of annexin A1 in expression of matrix metalloproteinase-9 and invasion of breast cancer cells Biochem Biophys Res Commun 423 2012 188 194
71. M. de Graauw, M.H. van Miltenburg, M.K. Schmidt, C. Pont, R. Lalai, and J. Kartopawiro Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells Proc Natl Acad Sci U S A 107 2010 6340 6345
72. M. Yi, and J.E. Schnitzer Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice Proc Natl Acad Sci U S A 106 2009 17886 17891
73. M. Pederzoli-Ribeil, F. Maione, D. Cooper, A. Al-Kashi, J. Dalli, and M. Perretti Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature Blood 116 2010 4288 4296
74. H.S. Euzger, R.J. Flower, N.J. Goulding, and M. Perretti Differential modulation of annexin I binding sites on monocytes and neutrophils Mediators Inflamm 8 1999 53 62
75. Y. Sogawa, T. Ohyama, H. Maeda, and K. Hirahara Inhibition of neutrophil migration in mice by mouse formyl peptide receptors 1 and 2 dual agonist: indication of cross-desensitization in vivo Immunology 132 2011 441 450
76. C.D. Dinardo, A. Ogdie, E.O. Hexner, N.V. Frey, A.W. Loren, and S.M. Luger Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease Leuk Lymphoma 2012
77. X. Liu, J. Ji, A. Forsti, K. Sundquist, J. Sundquist, and K. Hemminki Autoimmune diseases and subsequent urological cancers J Urol 2012
78. P. Maddison, and B. Lang Paraneoplastic neurological autoimmunity and survival in small-cell lung cancer J Neuroimmunol 201-202 2008 159 162