Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 42, 2009, Pages 17886-17891

  Yi, Ming ^a   Schnitzer, Jan E ^a  

^a SIDNEY KIMMEL CANCER CENTER   (United States)

Author keywords

Cancer targets; Systems biology; Tumor microenvironment; Tumor vasculature

Indexed keywords

LIPOCORTIN 1;

ADENOVIRUS; ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; ENDOTHELIUM CELL; GENE CONTROL; GENE EXPRESSION; METASTASIS; MICROENVIRONMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; SYSTEM ANALYSIS; TISSUE REPAIR; TUMOR GROWTH; TUMOR NECROSIS; TUMOR VASCULARIZATION; VASCULAR RING; VIRUS EXPRESSION; WOUND HEALING;

ANIMALS; ANNEXIN A1; CARCINOMA, LEWIS LUNG; CELL LINE, TUMOR; FEMALE; GENE EXPRESSION PROFILING; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM METASTASIS; NEOPLASMS, EXPERIMENTAL; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; SYSTEMS BIOLOGY; WOUND HEALING;

MUS; RODENTIA;

EID: 70449601776     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0901324106     Document Type: Article

References (32)

1. Di Rosa M, Flower RJ, Hirata F, Parente L, Russo-Marie F (1984) Anti-phospholipase proteins. Prostaglandins 28:441-442.
2. Wallner BP, et al. (1986) Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity. Nature 320:77-81.
3. Lim LH, Pervaiz S (2007) Annexin 1: the new face of an old molecule. FASEB J 21:968-975.
4. Hannon R, et al. (2003) Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J 17:253-255.
5. Oh P, et al. (2004) Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature 429:629-635. (Pubitemid 38812308)
6. Nicosia RF, Zhu WH, Fogel E, Howson KM, Aplin AC (2005) A new ex vivo model to study venous angiogenesis and arterio-venous anastomosis formation. J Vasc Res 42:111-119. (Pubitemid 41201976)
7. Baker AH, Edwards DR, Murphy G (2002) Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J Cell Sci 115:3719-3727. (Pubitemid 35203598)
8. Seo DW, et al. (2003) TIMP-2 mediated inhibition of angiogenesis: an MMP-independent mechanism. Cell 114:171-180.
9. Saunders WB, et al. (2006) Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol 175:179-191.
10. Lee MJ, et al. (1999) Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate. Cell 99:301-312.
11. Oyama O, et al. (2008) The lysophospholipid mediator sphingosine-1- phosphate promotes angiogenesis in vivo in ischaemic hindlimbs of mice. Cardiovasc Res 78:301-307. (Pubitemid 351556099)
12. Schwalm S, et al. (2008) Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells. Biochem Biophys Res Commun 368:1020-1025.
13. Vadas M, Xia P, McCaughan G, Gamble J (2008) The role of sphingosine kinase 1 in cancer: oncogene or non-oncogene addiction? Biochim Biophys Acta 1781:442-447.
14. Shweiki D, Itin A, Soffer D, Keshet E (1992) Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359:843-845.
15. Heldin CH, Usuki K, Miyazono K (1991) Platelet-derived endothelial cell growth factor. J Cell Biochem 47:208-210. (Pubitemid 121006995)
16. Akiyama S, et al. (2004) The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression. Cancer Sci 95:851-857. (Pubitemid 40045518)
17. Lu ZH, Wright JD, Belt B, Cardiff RD, Arbeit JM (2007) Hypoxia-inducible factor-1 facilitates cervical cancer progression in human papillomavirus type 16 transgenic mice. Am J Pathol 171:667-681. (Pubitemid 47344698)
18. Granata R, et al. (2007) Insulin-like growth factor binding protein-3 induces angiogenesis through IGF-I- and SphK1-dependent mechanisms. J Thromb Haemost 5:835-845. (Pubitemid 46563585)
19. Achen MG, Williams RA, Baldwin ME, Lai P, Roufail S, et al. (2002) The angiogenic and lymphangiogenic factor vascular endothelial growth factor-D exhibits a paracrine mode of action in cancer. Growth Factors 20:99-107. (Pubitemid 34823457)
20. Orlandini M, Marconcini L, Ferruzzi R, Oliviero S (1996) Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family. Proc Natl Acad Sci USA 93:11675-11680. (Pubitemid 26347181)
21. Mi H, Guo N, Kejariwal A, Thomas PD (2007) PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways. Nucleic Acids Res 35:D247-D252. (Pubitemid 46056208)
22. Thomas PD, et al. (2003) PANTHER: a library of protein families and subfamilies indexed by function. Genome Res 13:2129-2141.
23. Gavins FN, Dalli J, Flower RJ, Granger DN, Perretti M (2007) Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation. FASEB J 21:1751-1758. (Pubitemid 46855621)
24. Kuwano M, et al. (2003) The basic and clinical implications of ABC transporters, Y-box-binding protein-1 (YB-1) and angiogenesis-related factors in human malignancies. Cancer Sci 94:9-14. (Pubitemid 36575851)
25. Fukumura D, et al. (2001) Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci USA 98:2604-2609. (Pubitemid 32209529)
26. Williams TM, et al. (2005) Caveolin-1 promotes tumor progression in an autochthonous mouse model of prostate cancer: genetic ablation of Cav-1 delays advanced prostate tumor development in tramp mice. J Biol Chem 280:25134-25145.
27. Ferrara N, et al. (1996) Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380:439-442. (Pubitemid 26102720)
28. Fong GH, Rossant J, Gertsenstein M, Breitman ML (1995) Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376:66-70.
29. Shalaby F, et al. (1995) Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 376:62-66.
30. Jones N, et al. (2001) Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function. EMBO Rep 2:438-445. (Pubitemid 32509961)
31. Xia X, McClelland M, Wang Y (2005) WebArray: an online platform for microarray data analysis. BMC Bioinformatics 6:306. (Pubitemid 43046091)
32. Ashburner M, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25:25-29.