Developing better biomarkers for connective tissue disease-associated interstitial lung disease: Citrullinated hsp90 autoantibodies in rheumatoid arthritis

Arthritis and Rheumatism

Volumn 65, Issue 4, 2013, Pages 864-868

  Deane, Kevin D ^a   Nicolls, Mark R ^b,c  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ENOLASE; ARGININE; AUTOANTIBODY; BIOLOGICAL MARKER; CITRULLINE; FIBRIN ANTIBODY; HEAT SHOCK PROTEIN 90; INDOLEAMINE 2,3 DIOXYGENASE; INTERCELLULAR ADHESION MOLECULE 1; JO 1 ANTIBODY;

B LYMPHOCYTE; CELLULAR IMMUNITY; COMPUTER ASSISTED TOMOGRAPHY; CONNECTIVE TISSUE DISEASE; DENDRITIC CELL; DISEASE COURSE; HUMAN; IMMUNOLOGICAL TOLERANCE; IMMUNOPHENOTYPING; INTERSTITIAL LUNG DISEASE; LUNG INJURY; LUNG PARENCHYMA; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; RHEUMATOID ARTHRITIS; SENSITIVITY AND SPECIFICITY;

ARTHRITIS, RHEUMATOID; AUTOANTIGENS; CITRULLINE; FEMALE; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LUNG DISEASES, INTERSTITIAL; MALE; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84875691101     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.37878     Document Type: Review

References (35)

1. Fischer A, West SG, Swigris JJ, Brown KK, du Bois RM,. Connective tissue disease-associated interstitial lung disease: a call for clarification. Chest 2010; 138: 251-6.
2. + cells modulate pulmonary immune responses by production of indoleamine 2,3-dioxygenase. Am J Respir Cell Mol Biol 2004; 30: 311-8.
3. Schellekens GA, de Jong BA, van den Hoogen FH, van de Putte LB, van Venrooij WJ,. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies. J Clin Invest 1998; 101: 273-81.
4. Van Venrooij WJ, Pruijn GJ,. Citrullination: a small change for a protein with great consequences for rheumatoid arthritis. Arthritis Res 2000; 2: 249-51.
5. Rantapaa-Dahlqvist S, de Jong BA, Berglin E, Hallmans G, Wadell G, Stenlund H, et al. Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis. Arthritis Rheum 2003; 48: 2741-9.
6. Harlow L, Rosas IO, Gochuico BR, Mikuls TR, Dellaripa PF, Oddis CV, et al. Identification of citrullinated Hsp90 isoforms as novel autoantigens in rheumatoid arthritis-associated interstitial lung disease. Arthritis Rheum 2013; 65: 869-79.
7. Horton MR,. Rheumatoid arthritis associated interstitial lung disease. Crit Rev Comput Tomogr 2004; 45: 429-40.
8. Labirua A, Lundberg IE,. Interstitial lung disease and idiopathic inflammatory myopathies: progress and pitfalls. Curr Opin Rheumatol 2010; 22: 633-8.
9. Levine SM, Raben N, Xie D, Askin FB, Tuder R, Mullins M, et al. Novel conformation of histidyl-transfer RNA synthetase in the lung: the target tissue in Jo-1 autoantibody-associated myositis. Arthritis Rheum 2007; 56: 2729-39.
10. Fathi M, Vikgren J, Boijsen M, Tylen U, Jorfeldt L, Tornling G, et al. Interstitial lung disease in polymyositis and dermatomyositis: longitudinal evaluation by pulmonary function and radiology. Arthritis Rheum 2008; 59: 677-85.
11. Targoff IN,. Autoantibodies and their significance in myositis. Curr Rheumatol Rep 2008; 10: 333-40.
12. Vancsa A, Csipo I, Nemeth J, Devenyi K, Gergely L, Danko K,. Characteristics of interstitial lung disease in SS-A positive/Jo-1 positive inflammatory myopathy patients. Rheumatol Int 2009; 29: 989-94.
13. Sato S, Hirakata M, Kuwana M, Suwa A, Inada S, Mimori T, et al. Autoantibodies to a 140-kd polypeptide, CADM-140, in Japanese patients with clinically amyopathic dermatomyositis. Arthritis Rheum 2005; 52: 1571-6.
14. Sem M, Molberg O, Lund MB, Gran JT,. Rituximab treatment of the anti-synthetase syndrome: a retrospective case series. Rheumatology (Oxford) 2009; 48: 968-71.
15. Barbasso Helmers S, Englund P, Engstrom M, Ahlin E, Fathi M, Janciauskiene S, et al. Sera from anti-Jo-1-positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells. Arthritis Rheum 2009; 60: 2524-30.
16. Wegner N, Lundberg K, Kinloch A, Fisher B, Malmstrom V, Feldmann M, et al. Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis. Immunol Rev 2010; 233: 34-54.
17. Sokolove J, Bromberg R, Deane KD, Lahey LJ, Derber LA, Chandra PE, et al. Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis. PLoS One 2012; 7: e35296.
18. Van de Stadt LA, van der Horst AR, de Koning MH, Bos WH, Wolbink GJ, van de Stadt RJ, et al. The extent of the anti-citrullinated protein antibody repertoire is associated with arthritis development in patients with seropositive arthralgia. Ann Rheum Dis 2011; 70: 128-33.
19. Demoruelle MK, Deane K,. Antibodies to citrullinated protein antigens (ACPAs): clinical and pathophysiologic significance. Curr Rheumatol Rep 2011; 13: 421-30.
20. Zhao X, Okeke NL, Sharpe O, Batliwalla FM, Lee AT, Ho PP, et al. Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. Arthritis Res Ther 2008; 10: R94.
21. Lundberg K, Nijenhuis S, Vossenaar ER, Palmblad K, van Venrooij WJ, Klareskog L, et al. Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity. Arthritis Res Ther 2005; 7: R458-67.
22. Harre U, Georgess D, Bang H, Bozec A, Axmann R, Ossipova E, et al. Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. J Clin Invest 2012; 122: 1791-802.
23. Rangel-Moreno J, Hartson L, Navarro C, Gaxiola M, Selman M, Randall TD,. Inducible bronchus-associated lymphoid tissue (iBALT) in patients with pulmonary complications of rheumatoid arthritis. J Clin Invest 2006; 116: 3183-94.
24. Twigg HL III,. Humoral immune defense (antibodies): recent advances. Proc Am Thorac Soc 2005; 2: 417-21.
25. Klareskog L, Gregersen PK, Huizinga TW,. Prevention of autoimmune rheumatic disease: state of the art and future perspectives. Ann Rheum Dis 2010; 69: 2062-6.
26. Makrygiannakis D, Hermansson M, Ulfgren AK, Nicholas AP, Zendman AJ, Eklund A, et al. Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells. Ann Rheum Dis 2008; 67: 1488-92.
27. Saag KG, Kolluri S, Koehnke RK, Georgou TA, Rachow JW, Hunninghake GW, et al. Rheumatoid arthritis lung disease: determinants of radiographic and physiologic abnormalities. Arthritis Rheum 1996; 39: 1711-9.
28. Hacker S, Lambers C, Hoetzenecker K, Pollreisz A, Aigner C, Lichtenauer M, et al. Elevated HSP27, HSP70 and HSP90 α in chronic obstructive pulmonary disease: markers for immune activation and tissue destruction. Clin Lab 2009; 55: 31-40.
29. Botton E, Saraux A, Laselve H, Jousse S, Le Goff P,. Musculoskeletal manifestations in cystic fibrosis. Joint Bone Spine 2003; 70: 327-35.
30. Al-Shamma MR, McSharry C, McLeod K, McCruden EA, Stack BH,. Role of heat shock proteins in the pathogenesis of cystic fibrosis arthritis. Thorax 1997; 52: 1056-9.
31. Mori S, Koga Y, Sugimoto M,. Different risk factors between interstitial lung disease and airway disease in rheumatoid arthritis. Respir Med 2012; 106: 1591-9.
32. Gizinski AM, Mascolo M, Loucks JL, Kervitsky A, Meehan RT, Brown KK, et al. Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA. Clin Rheumatol 2009; 28: 611-3.
33. Demoruelle MK, Weisman MH, Simonian PL, Lynch DA, Sachs PB, Pedraza IF, et al. Airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity? Arthritis Rheum 2012; 64: 1756-61.
34. Fischer A, Solomon JJ, du Bois RM, Deane KD, Olson AL, Fernandez-Perez ER, et al. Lung disease with anti-CCP antibodies but not rheumatoid arthritis or connective tissue disease. Respir Med 2012; 106: 1040-7.
35. Brown KK,. Rheumatoid lung disease. Proc Am Thorac Soc 2007; 4: 443-8.