A highly sensitive and selective method for the determination of leukotriene B4 (LTB4) in ex vivo stimulated human plasma by ultra fast liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 925, Issue , 2013, Pages 54-62

  Lin, Weisheng ^a   Huang, Mike Qingtao ^b   Xue, Xiaohua ^c   Bertelsen, Kirk ^d   Chen, Guiyan ^a   Zhao, Harry ^a   Lin, Zhongping ^a   Fourie, Anne ^c   de Jong, Jan ^c   Weng, Naidong ^b  

^a Frontage Laboratories Inc   (United States)

^b JOHNSON AND JOHNSON   (United States)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Bioanalysis; Leukotriene B4 (LTB4); PD biomarker; Ultra fast liquid chromatography tandem mass spectrometry (UFLC MS MS)

Indexed keywords

ACCURACY AND PRECISION; BIOANALYSIS; BIOANALYTICAL METHODS; CHROMATOGRAPHIC SEPARATIONS; HUMAN PLASMA SAMPLES; LEUKOTRIENE B4 (LTB4); LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; METHYL TERTIARY BUTYL ETHER;

ASSAYS; CHROMATOGRAPHY; DIGITAL STORAGE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMERS; MASS SPECTROMETRY; PLASMA (HUMAN);

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

LEUKOTRIENE B4;

ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; DRUG STORAGE; ENZYME LINKED IMMUNOSORBENT ASSAY; EX VIVO STUDY; FREEZE THAWING; HUMAN; LIMIT OF QUANTITATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROOM TEMPERATURE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; HUMANS; LEUKOTRIENE B4; LINEAR MODELS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84875632396     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.02.038     Document Type: Article

References (25)

1. Zagryagskaya A.N., Aleksandrov D.A., Pushkareva M.A., Galkina S.I., Grishina Z.V., Sud'ina G.F. J. Immunotoxicol. 2008, 5:347-352.
2. Denis D., Riendeau D. Eur. Pharmacol. J. 1999, 367:343-350.
3. Pettersson A., Sabirsh A., Bristulf J., Kidd-Ljunggren K., Ljungberg B., Owman C., Karlsson U. J. Leukoc. Biol. 2005, 77:1018-1025.
4. Huang L., Zhao A., Wong F., Ayala J.M., Struthers M., Ujjainwalla F., Wright S.D., Springer M.S., Evans J., Cui J. Arterioscler. Thromb. Vasc. Biol. 2004, 24:1783-1788.
5. Serezani C.H., Lewis C., Jancar S., Peters-Golden M. J. Clin. Invest. 2011, 121:671-682.
6. Finney-Hayward T.K., Bahra P., Li S., Poll C.T., Nicholson A.G., Russell R.E., Ford P.A., Westwick J., Fenwick P.S., Barnes P.J., Donnelly L.E. Eur. Respir. J. 2009, 33:1105-1112.
7. Salmon J.A., Simmons P.M., Palmer R.M. Prostaglandins 1982, 24:225-235.
8. Salmon J.A. Adv. Prostaglandin Thromboxane Leukot. Res. 1985, 15:25-28.
9. Mathews W.R., Bundy G.L., Wynalda M.A., Guido D.M., Schneider W.P., Fitzpatrick F.A. Anal. Chem. 1988, 60:349-353.
10. Hughes H., Mitchell J.R., Gaskell S.J. Anal. Biochem. 1989, 179:304-308.
11. Takamoto M., Yano T., Shintani T., Hiraku S. J. Pharm. Biomed. Anal. 1995, 13:1465-1472.
12. Doyle M.J., Eichhold T.H., Hynd B.A., Weisman S.M. J. Pharm. Biomed. Anal. 1990, 8:137-142.
13. Mathews W.R. Methods Enzymol. 1990, 187:76-81.
14. Antoine C., Lellouche J.P., Maclouf J., Pradelles P. Biochim. Biophys. Acta 1991, 1075:162-168.
15. Mathews W.R., Rokach J., Murphy R.C. Anal. Biochem. 1981, 118:96-101.
16. Celardo A., Dell'Elba G., Eltantawy Z.M., Evangelista V., Cerletti C. J. Chromatogr. B: Biomed. Appl. 1994, 658:261-269.
17. Yamaguchi M., Takehiro O., Ishida J., Nakamura M. Chem. Pharm. Bull. (Tokyo) 1989, 37:2846-2848.
18. Herrmann T., Steinhilber D., Roth H.J. J. Chromatogr. 1987, 416:170-175.
19. Shak S. Methods Enzymol. 1987, 141:355-371.
20. Huwyler J., Gut J. Anal. Biochem. 1990, 188:374-382.
21. Panchaud A., Avois L., Roulet M., Pilet M., Hug C., Saugy M., Decosterd L.A. Anal. Biochem. 2005, 341:58-68.
22. Dawson M., McGee C.M., Brooks P.M., Vine J.H., Watson T.R. Biomed. Environ. Mass Spectrom. 1988, 17:205-211.
23. Tsikas D., Fauler J., Frolich J.C. Eicosanoids 1992, 5(Suppl.):S7-S9.
24. Tsikas D., Fauler J., Velasquez R.D., Gutzki F.M., Frolich J.C. Anal. Biochem. 1996, 236:175-178.
25. Chappell G.P., Xiao X., Pica-Mendez A., Varnell T., Green S., Tanaka W.K., Laterza O. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2011, 879:277-284.