메뉴 건너뛰기




Volumn 28, Issue 4, 2013, Pages 671-677

Des-gamma-carboxy prothrombin identified by P-11 and P-16 antibodies reflects prognosis for patients with hepatocellular carcinoma

Author keywords

AFP L3; Alpha fetoprotein; DCP; Hepatocellular carcinoma; NX PVKA; Prognosis

Indexed keywords

ALPHA FETOPROTEIN; ANTIBODY; DECARBOXYPROTHROMBIN; P 11 ANTIBODY; P 16 ANTIBODY; UNCLASSIFIED DRUG;

EID: 84875618289     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12076     Document Type: Article
Times cited : (11)

References (33)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag HM, Lenhard RK. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-2576.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.M.1    Lenhard, R.K.2
  • 3
    • 0021273094 scopus 로고
    • Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma
    • Liebman HA, Furie BC, Tong MJ etal. Des-gamma-carboxy (abnormal) prothrombin as a serum marker of primary hepatocellular carcinoma. N. Engl. J. Med. 1984; 310: 1427-1431.
    • (1984) N. Engl. J. Med. , vol.310 , pp. 1427-1431
    • Liebman, H.A.1    Furie, B.C.2    Tong, M.J.3
  • 4
    • 0033557988 scopus 로고    scopus 로고
    • Measurement of serum levels of des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma by a revised enzyme immunoassay kit with increased sensitivity
    • Okuda H, Nakanishi T, Takatsu K etal. Measurement of serum levels of des-gamma-carboxy prothrombin in patients with hepatocellular carcinoma by a revised enzyme immunoassay kit with increased sensitivity. Cancer 1999; 85: 812-818.
    • (1999) Cancer , vol.85 , pp. 812-818
    • Okuda, H.1    Nakanishi, T.2    Takatsu, K.3
  • 5
    • 0019958515 scopus 로고
    • Decarboxylation of gamma-carboxyglutamic acid residues in human prothrombin
    • Bajaj SP, Price PA, Russell WA. Decarboxylation of gamma-carboxyglutamic acid residues in human prothrombin. J. Biol. Chem. 1982; 257: 3726-3731.
    • (1982) J. Biol. Chem. , vol.257 , pp. 3726-3731
    • Bajaj, S.P.1    Price, P.A.2    Russell, W.A.3
  • 6
    • 0037165762 scopus 로고    scopus 로고
    • γ-Carboxyglutamic acid content of hepatocellular carcinoma-associated des-γ-carboxy prothrombin
    • Naraki T, Kohno N, Saito H etal. γ-Carboxyglutamic acid content of hepatocellular carcinoma-associated des-γ-carboxy prothrombin. Biochim. Biophys. Acta 2002; 1586: 287-298.
    • (2002) Biochim. Biophys. Acta , vol.1586 , pp. 287-298
    • Naraki, T.1    Kohno, N.2    Saito, H.3
  • 7
    • 84860249731 scopus 로고    scopus 로고
    • Novel method to measure serum levels of des-gamma-carboxy prothrombin for hepatocellular carcinoma in patients taking warfarin: a preliminary report
    • Toyoda H, Kumda T, Osaki Y etal. Novel method to measure serum levels of des-gamma-carboxy prothrombin for hepatocellular carcinoma in patients taking warfarin: a preliminary report. Cancer Sci. 2012; 103: 921-925.
    • (2012) Cancer Sci. , vol.103 , pp. 921-925
    • Toyoda, H.1    Kumda, T.2    Osaki, Y.3
  • 8
    • 0022352697 scopus 로고
    • Fucosylated alpha-fetoprotein as marker of early hepatocellular carcinoma
    • Aoyagi Y, Isemura M, Suzuki Y etal. Fucosylated alpha-fetoprotein as marker of early hepatocellular carcinoma. Lancet 1985; 326: 1353-1354.
    • (1985) Lancet , vol.326 , pp. 1353-1354
    • Aoyagi, Y.1    Isemura, M.2    Suzuki, Y.3
  • 9
    • 0027154890 scopus 로고
    • Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein
    • Sato Y, Nakata K, Kato Y etal. Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein. N. Engl. J. Med. 1993; 328: 1802-1806.
    • (1993) N. Engl. J. Med. , vol.328 , pp. 1802-1806
    • Sato, Y.1    Nakata, K.2    Kato, Y.3
  • 10
    • 0021859365 scopus 로고
    • Effect of vitamin K administration on acarboxyprothrombin (PIVKA-II) levels in newborns
    • Motohara K, Endo F, Matsuda I. Effect of vitamin K administration on acarboxyprothrombin (PIVKA-II) levels in newborns. Lancet 1985; 326: 242-244.
    • (1985) Lancet , vol.326 , pp. 242-244
    • Motohara, K.1    Endo, F.2    Matsuda, I.3
  • 11
    • 0021964966 scopus 로고
    • Detection of vitamin deficiency by use of an enzyme-linked immunosorbent assay for circulating for circulating abnormal prothrombin
    • Motohara K, Kuroki Y, Kan HK etal. Detection of vitamin deficiency by use of an enzyme-linked immunosorbent assay for circulating for circulating abnormal prothrombin. Pediatr. Res. 1985; 19: 354-357.
    • (1985) Pediatr. Res. , vol.19 , pp. 354-357
    • Motohara, K.1    Kuroki, Y.2    Kan, H.K.3
  • 12
    • 0016355478 scopus 로고
    • A new look at statistical model identification
    • Akaike H. A new look at statistical model identification. IEEE Trans. Automat. Control 1974; 19: 716-723.
    • (1974) IEEE Trans. Automat. Control , vol.19 , pp. 716-723
    • Akaike, H.1
  • 13
    • 0028291568 scopus 로고
    • Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma
    • Suehiro T, Sugimachi K, Matsumata T, Itasaka H, Taketomi A, Maeda T. Protein induced by vitamin K absence or antagonist II as a prognostic marker in hepatocellular carcinoma. Cancer 1994; 73: 2464-2469.
    • (1994) Cancer , vol.73 , pp. 2464-2469
    • Suehiro, T.1    Sugimachi, K.2    Matsumata, T.3    Itasaka, H.4    Taketomi, A.5    Maeda, T.6
  • 14
    • 33947575209 scopus 로고    scopus 로고
    • Prognostic factors for portal venous invasion in patients with hepatocellular carcinoma
    • Hagiwara S, Kudo M, Kawasaki T etal. Prognostic factors for portal venous invasion in patients with hepatocellular carcinoma. J. Gastroenterol. 2006; 41: 1214-1219.
    • (2006) J. Gastroenterol. , vol.41 , pp. 1214-1219
    • Hagiwara, S.1    Kudo, M.2    Kawasaki, T.3
  • 15
    • 41149128806 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin as an important prognostic indicator in patients with small hepatocellular carcinoma
    • Hakamada K, Kimura N, Miura T etal. Des-gamma-carboxy prothrombin as an important prognostic indicator in patients with small hepatocellular carcinoma. World J. Gastroenterol. 2008; 14: 1370-1377.
    • (2008) World J. Gastroenterol. , vol.14 , pp. 1370-1377
    • Hakamada, K.1    Kimura, N.2    Miura, T.3
  • 16
    • 60049099362 scopus 로고    scopus 로고
    • High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma
    • Kobayashi M, Ikeda K, Kawamura Y etal. High serum des-gamma-carboxy prothrombin level predicts poor prognosis after radiofrequency ablation of hepatocellular carcinoma. Cancer 2009; 115: 571-580.
    • (2009) Cancer , vol.115 , pp. 571-580
    • Kobayashi, M.1    Ikeda, K.2    Kawamura, Y.3
  • 17
    • 84865116374 scopus 로고    scopus 로고
    • Predictors for microinvasion of small hepatocellular carcinoma <2cm
    • Yamashita Y, Tsuijita E, Takeishi K etal. Predictors for microinvasion of small hepatocellular carcinoma <2cm. Ann. Surg. Oncol. 2012; 19: 2027-2034.
    • (2012) Ann. Surg. Oncol. , vol.19 , pp. 2027-2034
    • Yamashita, Y.1    Tsuijita, E.2    Takeishi, K.3
  • 18
    • 80053605097 scopus 로고    scopus 로고
    • Protein induced by vitamin K absence or antagonist-II production is a strong predictive marker for extrahepatic metastases in early hepatocellular carcinoma: a prospective evaluation
    • Bae HM, Lee JH, Yoon JH, Kim YJ, Heo DS, Lee HS. Protein induced by vitamin K absence or antagonist-II production is a strong predictive marker for extrahepatic metastases in early hepatocellular carcinoma: a prospective evaluation. BMC Cancer 2011; 11: 435-445.
    • (2011) BMC Cancer , vol.11 , pp. 435-445
    • Bae, H.M.1    Lee, J.H.2    Yoon, J.H.3    Kim, Y.J.4    Heo, D.S.5    Lee, H.S.6
  • 19
    • 82355191984 scopus 로고    scopus 로고
    • Des-gamma-carboxyprothrombin in patients with hepatocellular carcinoma and liver cirrhosis
    • Inagaki Y, Xu HL, Hasegawa K etal. Des-gamma-carboxyprothrombin in patients with hepatocellular carcinoma and liver cirrhosis. J. Dig. Dis. 2011; 12: 481-488.
    • (2011) J. Dig. Dis. , vol.12 , pp. 481-488
    • Inagaki, Y.1    Xu, H.L.2    Hasegawa, K.3
  • 20
    • 0021135218 scopus 로고
    • Regression modeling strategies for improved prognostic prediction
    • Harrell FE Jr, Lee KL, Califf RM etal. Regression modeling strategies for improved prognostic prediction. Stat. Med. 1984; 3: 143-152.
    • (1984) Stat. Med. , vol.3 , pp. 143-152
    • Harrell Jr, F.E.1    Lee, K.L.2    Califf, R.M.3
  • 21
    • 34548628973 scopus 로고    scopus 로고
    • Fucosylated fraction of alpha-fetoprotein, L3, as a useful prognostic factor in patients with hepatocellular carcinoma with special reference to low concentrations of serum alpha-fetoprotein
    • Kobayashi M, Kuroiwa T, Suda T etal. Fucosylated fraction of alpha-fetoprotein, L3, as a useful prognostic factor in patients with hepatocellular carcinoma with special reference to low concentrations of serum alpha-fetoprotein. Hepatol. Res. 2007; 37: 914-922.
    • (2007) Hepatol. Res. , vol.37 , pp. 914-922
    • Kobayashi, M.1    Kuroiwa, T.2    Suda, T.3
  • 22
    • 79958824201 scopus 로고    scopus 로고
    • Prognostic importance of fucosylated alpha-fetoprotein in hepatocellular carcinoma patients with low alpha-fetoprotein
    • Nouso K, Kobayashi Y, Nakamura S etal. Prognostic importance of fucosylated alpha-fetoprotein in hepatocellular carcinoma patients with low alpha-fetoprotein. J. Gastroenterol. Hepatol. 2011; 26: 1195-1200.
    • (2011) J. Gastroenterol. Hepatol. , vol.26 , pp. 1195-1200
    • Nouso, K.1    Kobayashi, Y.2    Nakamura, S.3
  • 23
    • 78650088633 scopus 로고    scopus 로고
    • Clinical and molecular instates into the hepatocellular carcinoma tumour marker des-γ-carboxy prothrombin
    • Inagaki Y, Tang W, Makuuchi M, Hasegawa K, Sugawara Y, Kokudo N. Clinical and molecular instates into the hepatocellular carcinoma tumour marker des-γ-carboxy prothrombin. Liver Int. 2011; 31: 22-35.
    • (2011) Liver Int. , vol.31 , pp. 22-35
    • Inagaki, Y.1    Tang, W.2    Makuuchi, M.3    Hasegawa, K.4    Sugawara, Y.5    Kokudo, N.6
  • 24
    • 0041627705 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin in cancer and non-cancer liver tissue of patients with hepatocellular carcinoma
    • Tang W, Miki K, Kokudo N etal. Des-gamma-carboxy prothrombin in cancer and non-cancer liver tissue of patients with hepatocellular carcinoma. Int. J. Oncol. 2003; 22: 969-975.
    • (2003) Int. J. Oncol. , vol.22 , pp. 969-975
    • Tang, W.1    Miki, K.2    Kokudo, N.3
  • 25
    • 33644693140 scopus 로고    scopus 로고
    • Distribution of the heterogeneity of des-γ-carboxyprothrombin in patients with hepatocellular carcinoma
    • Uehara S, Gotoh K, Handa H etal. Distribution of the heterogeneity of des-γ-carboxyprothrombin in patients with hepatocellular carcinoma. J. Gastroenterol. Hepatol. 2005; 20: 1545-1552.
    • (2005) J. Gastroenterol. Hepatol. , vol.20 , pp. 1545-1552
    • Uehara, S.1    Gotoh, K.2    Handa, H.3
  • 26
    • 0024427178 scopus 로고
    • Molecular cloning and expression of human hepatocyte growth factor
    • Nakamura T, Nishizawa T, Hagiya M etal. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989; 342: 440-443.
    • (1989) Nature , vol.342 , pp. 440-443
    • Nakamura, T.1    Nishizawa, T.2    Hagiya, M.3
  • 27
    • 14844290900 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin is a potential autologous growth factor for hepatocellular carcinoma
    • Suzuki M, Shiraha H, Fujikawa T etal. Des-gamma-carboxy prothrombin is a potential autologous growth factor for hepatocellular carcinoma. J. Biol. Chem. 2005; 280: 6409-6415.
    • (2005) J. Biol. Chem. , vol.280 , pp. 6409-6415
    • Suzuki, M.1    Shiraha, H.2    Fujikawa, T.3
  • 28
    • 0035190894 scopus 로고    scopus 로고
    • Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection
    • Pohl A, Behling C, Oliver D etal. Serum aminotransferase levels and platelet counts as predictors of degree of fibrosis in chronic hepatitis C virus infection. Am. J. Gastroenterol. 2001; 96: 3142-3146.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 3142-3146
    • Pohl, A.1    Behling, C.2    Oliver, D.3
  • 29
    • 70349546276 scopus 로고    scopus 로고
    • Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease
    • Shah AG, Lydecker A, Murray K etal. Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease. Clin. Gastroenterol. Hepatol. 2009; 7: 1104-1112.
    • (2009) Clin. Gastroenterol. Hepatol. , vol.7 , pp. 1104-1112
    • Shah, A.G.1    Lydecker, A.2    Murray, K.3
  • 30
    • 0035253469 scopus 로고    scopus 로고
    • Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma
    • Koike Y, Shiratori Y, Sato S etal. Des-gamma-carboxy prothrombin as a useful predisposing factor for the development of portal venous invasion in patients with hepatocellular carcinoma. Cancer 2001; 91: 561-569.
    • (2001) Cancer , vol.91 , pp. 561-569
    • Koike, Y.1    Shiratori, Y.2    Sato, S.3
  • 31
    • 0031782818 scopus 로고    scopus 로고
    • The Cancer of the Liver Italian Program (CLIP) Investigators. A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients
    • The Cancer of the Liver Italian Program (CLIP) Investigators. A new prognostic system for hepatocellular carcinoma: a retrospective study of 435 patients. Hepatology 1998; 28: 751-755.
    • (1998) Hepatology , vol.28 , pp. 751-755
  • 32
    • 0032879468 scopus 로고    scopus 로고
    • Prognosis of hepatocellular carcinoma: the BCLC staging classification
    • Llovet JM, Bru C, Bruix J. Prognosis of hepatocellular carcinoma: the BCLC staging classification. Semin. Liver Dis. 1999; 19: 329-338.
    • (1999) Semin. Liver Dis. , vol.19 , pp. 329-338
    • Llovet, J.M.1    Bru, C.2    Bruix, J.3
  • 33
    • 20044364922 scopus 로고    scopus 로고
    • Proposal of a new prognostic model for hepatocellular carcinoma: an analysis of 403 patients
    • Tateishi R, Yoshiba H, Shiina S etal. Proposal of a new prognostic model for hepatocellular carcinoma: an analysis of 403 patients. Gut 2005; 54: 419-425.
    • (2005) Gut , vol.54 , pp. 419-425
    • Tateishi, R.1    Yoshiba, H.2    Shiina, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.