Systemic Causes of Cholestasis

Clinics in Liver Disease

Volumn 17, Issue 2, 2013, Pages 301-317

  deLemos, Andrew S ^a,b   Friedman, Lawrence S ^a,b,c,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NEWTON WELLESLEY HOSPITAL   (United States)

Author keywords

Amyloidosis; Cholestasis of sepsis; Congestive hepatopathy; Granulomatous hepatitis; Lymphoma; Sarcoidosis; Sickle cell disease; Total parenteral nutrition

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; ANTINEOPLASTIC AGENT; BILIRUBIN; DIPEPTIDYL CARBOXYPEPTIDASE; PENICILLIN DERIVATIVE; TETRACYCLINE; URSODEOXYCHOLIC ACID; VALGANCICLOVIR;

ACTINOMYCOSIS; ACUTE LIVER FAILURE; ALKALINE PHOSPHATASE BLOOD LEVEL; AMYLOIDOSIS; ANAPHYLACTOID PURPURA; ANTIBIOTIC THERAPY; BACTERIAL INFECTION; BILE DUCT DISEASE; BILIRUBIN BLOOD LEVEL; BRUCELLOSIS; CANCER RADIOTHERAPY; CANDIDIASIS; CHOLESTASIS; CYTOMEGALOVIRUS INFECTION; DIABETIC HEPATOSCLEROSIS; ENTERITIS; EPSTEIN BARR VIRUS; ESCHERICHIA COLI; GRAFT VERSUS HOST REACTION; HEMOPHAGOCYTIC SYNDROME; HEPATITIS; HEPATOSPLENOMEGALY; HODGKIN DISEASE; HUMAN; HYPERBILIRUBINEMIA; HYPOVOLEMIC SHOCK; JAUNDICE; LIVER BIOPSY; LIVER CANDIDIASIS; LYMPHADENOPATHY; NONHODGKIN LYMPHOMA; NONHUMAN; PARENTERAL NUTRITION; PHYSICAL EXAMINATION; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PROTEIN BLOOD LEVEL; REVIEW; SARCOIDOSIS; SCLEROSING CHOLANGITIS; SECONDARY HYPERPARATHYROIDISM; SEPSIS; SICKLE CELL ANEMIA; SJOEGREN SYNDROME; SYSTEMIC SCLEROSIS; THYROID DISEASE; TRANSTHORACIC ECHOCARDIOGRAPHY; VIRUS LOAD; WEIGHT REDUCTION;

AMYLOIDOSIS; ANEMIA, SICKLE CELL; AUTOIMMUNE DISEASES; CHOLESTASIS; ENDOCRINE SYSTEM DISEASES; HEART FAILURE; HEPATITIS; HUMANS; LIVER DISEASES; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; LYMPHOMA; MYCOSES; SARCOIDOSIS; SEPSIS;

EID: 84875592851     PISSN: 10893261     EISSN: 15578224     Source Type: Journal    
DOI: 10.1016/j.cld.2012.11.001     Document Type: Review

References (82)

1. Osler W. The principles and practice of medicine: designed for the use of practitioners and students of medicine 1892, D. Appleton, New York.
2. Moseley R.H. Sepsis and cholestasis. Clin Liver Dis 1999, 3:465-475.
3. Tung C.B., Tung C.F., Yang D.Y., et al. Extremely high levels of alkaline phosphatase in adult patients as a manifestation of bacteremia. Hepatogastroenterology 2005, 52:1347-1350.
4. Hamilton J.R., Sass-Kortsak A. Jaundice associated with severe bacterial infection in young infants. J Pediatr 1963, 63:121-132.
5. Franson T.R., Hierholzer W.J., LaBrecque D.R. Frequency and characteristics of hyperbilirubinemia associated with bacteremia. Rev Infect Dis 1985, 7:1-9.
6. Sikuler E., Guetta V., Keynan A., et al. Abnormalities in bilirubin and liver enzyme levels in adult patients with bacteremia. A prospective study. Arch Intern Med 1989, 149:2246-2248.
7. Whitehead M.W., Hainsworth I., Kingham J.G. The causes of obvious jaundice in South West Wales: perceptions versus reality. Gut 2001, 48:409-413.
8. Fuchs M., Sanyal A.J. Sepsis and cholestasis. Clin Liver Dis 2008, 12:151-172. ix.
9. Geier A., Fickert P., Trauner M. Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis. Nat Clin Pract Gastroenterol Hepatol 2006, 3:574-585.
10. Chand N., Sanyal A.J. Sepsis-induced cholestasis. Hepatology 2007, 45:230-241.
11. Wagner M., Zollner G., Trauner M. New molecular insights into the mechanisms of cholestasis. J Hepatol 2009, 51:565-580.
12. Zollner G., Fickert P., Zenz R., et al. Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases. Hepatology 2001, 33:633-646.
13. Fahrlaender H., Huber F., Gloor F. Intrahepatic retention of bile in severe bacterial infections. Gastroenterology 1964, 47:590-599.
14. Engler S., Elsing C., Flechtenmacher C., et al. Progressive sclerosing cholangitis after septic shock: a new variant of vanishing bile duct disorders. Gut 2003, 52:688-693.
15. Benninger J., Grobholz R., Oeztuerk Y., et al. Sclerosing cholangitis following severe trauma: description of a remarkable disease entity with emphasis on possible pathophysiologic mechanisms. World J Gastroenterol 2005, 11:4199-4205.
16. Schmitt M., Kolbel C.B., Muller M.K., et al. Z Gastroenterol 1997, 35:929-934. [in German].
17. Scheppach W., Druge G., Wittenberg G., et al. Sclerosing cholangitis and liver cirrhosis after extrabiliary infections: report on three cases. Crit Care Med 2001, 29:438-441.
18. Seeto R.K., Rockey D.C. Pyogenic liver abscess. Changes in etiology, management, and outcome. Medicine (Baltimore) 1996, 75:99-113.
19. Zhu X., Wang S., Jacob R., et al. A 10-year retrospective analysis of clinical profiles, laboratory characteristics and management of pyogenic liver abscesses in a Chinese hospital. Gut Liver 2011, 5:221-227.
20. Chou F.F., Sheen-Chen S.M., Chen Y.S., et al. Single and multiple pyogenic liver abscesses: clinical course, etiology, and results of treatment. World J Surg 1997, 21:384-388. [discussion: 388-9].
21. Cheng H.C., Chang W.L., Chen W.Y., et al. Long-term outcome of pyogenic liver abscess: factors related with abscess recurrence. J Clin Gastroenterol 2008, 42:1110-1115.
22. Joshi V., Koulaouzidis A., McGoldrick S., et al. Actinomycotic liver abscess: a rare complication of colonic diverticular disease. Ann Hepatol 2010, 9:96-98.
23. Sharma M., Briski L.E., Khatib R. Hepatic actinomycosis: an overview of salient features and outcome of therapy. Scand J Infect Dis 2002, 34:386-391.
24. Stern M.S., Gitnick G.L. Shigella hepatitis. JAMA 1976, 235:2628.
25. Saebo A., Lassen J. Acute and chronic liver disease associated with Yersinia enterocolitica infection: a Norwegian 10-year follow-up study of 458 hospitalized patients. J Intern Med 1992, 231:531-535.
26. Cervantes F., Bruguera M., Carbonell J., et al. Liver disease in brucellosis. A clinical and pathological study of 40 cases. Postgrad Med J 1982, 58:346-350.
27. Janbon F. Gastroenterol Clin Biol 1999, 23:431-432. [in French].
28. den Haan P.J., van Vliet A.C., Hazenberg B.P. Weil's disease as a cause of jaundice. Neth J Med 1993, 42:171-174.
29. Mullick C.J., Liappis A.P., Benator D.A., et al. Syphilitic hepatitis in HIV-infected patients: a report of 7 cases and review of the literature. Clin Infect Dis 2004, 39:e100-e105.
30. Johnson T.L., Barnett J.L., Appelman H.D., et al. Candida hepatitis. Histopathologic diagnosis. Am J Surg Pathol 1988, 12:716-720.
31. Bucuvalas J.C., Bove K.E., Kaufman R.A., et al. Cholangitis associated with Cryptococcus neoformans. Gastroenterology 1985, 88:1055-1059.
32. Zangerl B., Edel G., von Manitius J., et al. Med Klin (Munich) 1998, 93:170-173. [in German].
33. Kumar N., Jain S., Singh Z.N. Disseminated histoplasmosis with reactive hemophagocytosis: aspiration cytology findings in two cases. Diagn Cytopathol 2000, 23:422-424.
34. Chong V.H. Hepatobiliary tuberculosis: a review of presentations and outcomes. South Med J 2008, 101:356-361.
35. Chong V.H., Lim K.S. Hepatobiliary tuberculosis. Singapore Med J 2010, 51:744-751.
36. Young L.S. Mycobacterium avium complex infection. J Infect Dis 1988, 157:863-867.
37. Hinedi T.B., Koff R.S. Cholestatic hepatitis induced by Epstein-Barr virus infection in an adult. Dig Dis Sci 2003, 48:539-541.
38. Snover D.C., Horwitz C.A. Liver disease in cytomegalovirus mononucleosis: a light microscopical and immunoperoxidase study of six cases. Hepatology 1984, 4:408-412.
39. Finegold M.J., Carpenter R.J. Obliterative cholangitis due to cytomegalovirus: a possible precursor of paucity of intrahepatic bile ducts. Hum Pathol 1982, 13:662-665.
40. Hasosah M.Y., Kutbi S.Y., Al-Amri A.W., et al. Perinatal cytomegalovirus hepatitis in Saudi infants: a case series. Saudi J Gastroenterol 2012, 18:208-213.
41. Agarwal S.K., Kalra V., Dinda A., et al. Fibrosing cholestatic hepatitis in renal transplant recipient with CMV infection: a case report. Int Urol Nephrol 2004, 36:433-435.
42. Khatib R., Siddique M., Abbass M. Measles associated hepatobiliary disease: an overview. Infection 1993, 21:112-114.
43. Cremers J., Drent M., Driessen A., et al. Liver-test abnormalities in sarcoidosis. Eur J Gastroenterol Hepatol 2012, 24:17-24.
44. Devaney K., Goodman Z.D., Epstein M.S., et al. Hepatic sarcoidosis. Clinicopathologic features in 100 patients. Am J Surg Pathol 1993, 17:1272-1280.
45. Alam I., Levenson S.D., Ferrell L.D., et al. Diffuse intrahepatic biliary strictures in sarcoidosis resembling sclerosing cholangitis. Case report and review of the literature. Dig Dis Sci 1997, 42:1295-1301.
46. Nakanuma Y., Kouda W., Harada K., et al. Hepatic sarcoidosis with vanishing bile duct syndrome, cirrhosis, and portal phlebosclerosis. Report of an autopsy case. J Clin Gastroenterol 2001, 32:181-184.
47. Alenezi B., Lamoureux E., Alpert L., et al. Effect of ursodeoxycholic acid on granulomatous liver disease due to sarcoidosis. Dig Dis Sci 2005, 50:196-200.
48. Ishak K.G. Sarcoidosis of the liver and bile ducts. Mayo Clin Proc 1998, 73:467-472.
49. Park M.A., Mueller P.S., Kyle R.A., et al. Primary (AL) hepatic amyloidosis: clinical features and natural history in 98 patients. Medicine (Baltimore) 2003, 82:291-298.
50. Molleran Lee S., Villanueva J., Sumegi J., et al. Characterisation of diverse PRF1 mutations leading to decreased natural killer cell activity in North American families with haemophagocytic lymphohistiocytosis. J Med Genet 2004, 41:137-144.
51. de Kerguenec C., Hillaire S., Molinie V., et al. Hepatic manifestations of hemophagocytic syndrome: a study of 30 cases. Am J Gastroenterol 2001, 96:852-857.
52. Ebert E.C., Nagar M., Hagspiel K.D. Gastrointestinal and hepatic complications of sickle cell disease. Clin Gastroenterol Hepatol 2010, 8:483-489. [quiz: e70].
53. Schubert T.T. Hepatobiliary system in sickle cell disease. Gastroenterology 1986, 90:2013-2021.
54. Lacaille F., Lesage F., de Montalembert M. Acute hepatic crisis in children with sickle cell disease. J Pediatr Gastroenterol Nutr 2004, 39:200-202.
55. Brunetta D.M., Silva-Pinto A.C., do Carmo Favarin de Macedo M., et al. Intrahepatic cholestasis in sickle cell disease: a case report. Anemia 2011, 2011:975731.
56. Friedman L.S. Liver transplantation for sickle cell hepatopathy. Liver Transpl 2007, 13:483-485.
57. Birrer M.J., Young R.C. Differential diagnosis of jaundice in lymphoma patients. Semin Liver Dis 1987, 7:269-277.
58. Perera D.R., Greene M.L., Fenster L.F. Cholestasis associated with extrabiliary Hodgkin's disease. Report of three cases and review of four others. Gastroenterology 1974, 67:680-685.
59. Hubscher S.G., Lumley M.A., Elias E. Vanishing bile duct syndrome: a possible mechanism for intrahepatic cholestasis in Hodgkin's lymphoma. Hepatology 1993, 17:70-77.
60. Ballonoff A., Kavanagh B., Nash R., et al. Hodgkin lymphoma-related vanishing bile duct syndrome and idiopathic cholestasis: statistical analysis of all published cases and literature review. Acta Oncol 2008, 47:962-970.
61. Noronha V., Shafi N.Q., Obando J.A., et al. Primary non-Hodgkin's lymphoma of the liver. Crit Rev Oncol Hematol 2005, 53:199-207.
62. Jain A., Nalesnik M., Reyes J., et al. Posttransplant lymphoproliferative disorders in liver transplantation: a 20-year experience. Ann Surg 2002, 236:429-436. [discussion: 436-7].
63. Kotlyar D.S., Osterman M.T., Diamond R.H., et al. A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2011, 9:36-41.e1.
64. Morla D., Alazemi S., Lichtstein D. Stauffer's syndrome variant with cholestatic jaundice: a case report. J Gen Intern Med 2006, 21:C11-C13.
65. Tuncer H.H., Rana N., Milani C., et al. Gastrointestinal and hepatic complications of hematopoietic stem cell transplantation. World J Gastroenterol 2012, 18:1851-1860.
66. Przepiorka D., Weisdorf D., Martin P., et al. 1994 consensus conference on acute GVHD grading. Bone Marrow Transplant 1995, 15:825-828.
67. Tay J., Tinmouth A., Fergusson D., et al. Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2007, 13:206-217.
68. Huang M.J., Liaw Y.F. Clinical associations between thyroid and liver diseases. J Gastroenterol Hepatol 1995, 10:344-350.
69. Regelmann M.O., Miloh T., Arnon R., et al. Graves' disease presenting with severe cholestasis. Thyroid 2012, 22:437-439.
70. Abdel Khalek M., Abd ElMageed Z., Khan A., et al. Cholestatic hepatitis in a patient with Graves' disease resolved with total thyroidectomy. Trop Gastroenterol 2011, 32:328-330.
71. Harrison S.A., Brunt E.M., Goodman Z.D., et al. Diabetic hepatosclerosis: diabetic microangiopathy of the liver. Arch Pathol Lab Med 2006, 130:27-32.
72. Chen G., Brunt E.M. Diabetic hepatosclerosis: a 10-year autopsy series. Liver Int 2009, 29:1044-1050.
73. Giallourakis C.C., Rosenberg P.M., Friedman L.S. The liver in heart failure. Clin Liver Dis 2002, 6:947-967. viii-ix.
74. van Lingen R., Warshow U., Dalton H.R., et al. Jaundice as a presentation of heart failure. J R Soc Med 2005, 98:357-359.
75. Seeto R.K., Fenn B., Rockey D.C. Ischemic hepatitis: clinical presentation and pathogenesis. Am J Med 2000, 109:109-113.
76. McCrindle B.W., Wood R.A., Nussbaum A.R. Henoch-Schönlein syndrome. Unusual manifestations with hydrops of the gallbladder. Clin Pediatr (Phila) 1988, 27:254-256.
77. Viola S., Meyer M., Fabre M., et al. Ischemic necrosis of bile ducts complicating Schönlein-Henoch purpura. Gastroenterology 1999, 117:211-214.
78. Navaneethan U., Shen B. Hepatopancreatobiliary manifestations and complications associated with inflammatory bowel disease. Inflamm Bowel Dis 2010, 16:1598-1619.
79. Rubio-Tapia A., Murray J.A. The liver in celiac disease. Hepatology 2007, 46:1650-1658.
80. Kubota A., Yonekura T., Hoki M., et al. Total parenteral nutrition-associated intrahepatic cholestasis in infants: 25 years' experience. J Pediatr Surg 2000, 35:1049-1051.
81. Cohen C., Olsen M.M. Pediatric total parenteral nutrition. Liver histopathology. Arch Pathol Lab Med 1981, 105:152-156.
82. Cowles R.A., Ventura K.A., Martinez M., et al. Reversal of intestinal failure-associated liver disease in infants and children on parenteral nutrition: experience with 93 patients at a referral center for intestinal rehabilitation. J Pediatr Surg 2010, 45:84-87. [discussion: 87-8].