Extremely high levels of alkaline phosphatase in adult patients as a manifestation of bacteremia

Hepato-Gastroenterology

Volumn 52, Issue 65, 2005, Pages 1347-1350

  Tung, Chun Bin ^a   Tung, Chun Fang ^b,d   Yang, Dar Yu ^b,c   Hu, Wei Hsiung ^b   Hung, Dong Zong ^b   Peng, Yen Chun ^b,d   Chang, Chi Sen ^b,c  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Alkaline phosphatase; Bacteremia; Malignancy

Indexed keywords

ALBUMIN; ALKALINE PHOSPHATASE; BILIRUBIN; CALCIUM;

ADULT; AGED; ALKALINE PHOSPHATASE BLOOD LEVEL; BACTEREMIA; BACTERIUM IDENTIFICATION; BILE DUCT OBSTRUCTION; BILIRUBIN BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL FEATURE; COMORBIDITY; CONTROLLED STUDY; DIABETES MELLITUS; ESCHERICHIA COLI; EVALUATION; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; LIVER DYSFUNCTION; MALE; MALIGNANT BILIARY OBSTRUCTION; MEDICAL RECORD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; RISK FACTOR; TAIWAN;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALKALINE PHOSPHATASE; BACTEREMIA; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; BONE NEOPLASMS; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; CHOLESTASIS; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 25844451632     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (20)

1. Van Hoof VO, De Broe ME: Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns. Crit Rev Clin Lab Sci 1994; 31:197-293.
2. Calvo MS, Eyre DR, Gundberg CM: Molecular basis and clinical application of biological markers of bone turnover. Endocr Rev 1996; 17:333-368.
3. Roberts WM: Variations of the phosphatase activity in the blood in disease. Br J Exp Pathol 1930; 11:90-95.
4. Neuschwander Tetri BA: Common blood tests for liver disease. Which ones are most useful? Postgrad Med 1995; 98:49-56, 59, 63.
5. Zimmerman HJ, Fang M, Utili R, et al: Jaundice due to bacterial infection. Gastroenterology 1979; 77:362-374.
6. Franson TR, Hierholzer WJ Jr, LaBrecque DR: Frequency and characteristics of hyperbilirubinemia associated with bacteremia. Rev Infect Dis 1985; 7:1-9.
7. Sikuler E, Guetta V, Keynan A, et al: Abnormalities in bilirubin and liver enzyme levels in adult patients with bacteremia: a prospective study. Arch Intern Med 1989; 149:2246-2248.
8. Brooks GS, Zimbler AG, Bodenheimer HC Jr, et al: Patterns of liver test abnormalities in patients with surgical sepsis. Am Surg 1991; 57:656-662.
9. Hamilton JR, Sass-Kortsak A: Jaundice associated with severe bacterial infection in young infants. J Pediatr 1963; 63:121-132.
10. Rooney JC, Hill DJ, Danks DM: Jaundice associated with bacterial infection in the newborn. Am J Dis Child 1971; 122:39-41.
11. Fang MH, Ginsberg AL, Dobbins WO III: Marked elevation in serum alkaline phosphatase activity as a manifestation of systemic infection. Gastroenterology 1980; 78:592-597.
12. Maldonado O, Demasi R, Maldonado Y, et al: Extremely high levels of alkaline phosphatase in hospitalized patients. J Clin Gastroenterol 1998; 27:342-345.
13. Lieberman D, Phillips D: "Isolated" elevation of alkaline phosphatase: significance in hospitalized patients. J Clin Gastroenterol 1990; 12:415-419.
14. Kaplan MM: Serum alkaline phosphatase-another piece is added to the puzzle. Hepatology 1986; 6:526-528.
15. Gordon T: Factors associated with serum alkaline phosphatase level. Arch Pathol Lab Med 1993; 117:187-190.
16. Reichling JJ, Kaplan MM: Clinical use of serum enzymes in liver disease. Dig Dis Sci 1988; 33:1601-1614.
17. Vermillion SE, Gregg JA, Baggenstoss AH, et al: Jaundice associated with bacteremia. Arch Intern Med 1969; 124:611-618.
18. Miller DJ, Keeton GR, Webber BL, et al: Jaundice in severe bacterial infection. Gastroenterology 1976; 71:94-97.
19. Utili R, Abernathy CO, Zimmerman HJ: Inhibition of Na+, K+-adenosinetriphosphatase by endotoxin: a possible mechanism for endotoxin-induced cholestasis. J Infect Dis 1977; 136:583-587.
20. Gimson AES: Hepatic dysfunction during bacterial sepsis. Intensive Care Med 1987; 13:162-166.