How to target MHC class II into the MIIC compartment

Molecular Immunology

Volumn 55, Issue 2, 2013, Pages 162-165

  Garstka, Malgorzata A ^a   Neefjes, Jacques ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

MHC class II; MIIC; Targeting; Ubiquitin

Indexed keywords

ADAPTOR PROTEIN; COAT PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MOLECULAR MOTOR; SCAFFOLD PROTEIN; SMALL INTERFERING RNA;

ANTIGEN BINDING; CD4+ T LYMPHOCYTE; GENETIC SCREENING; IMMUNE RESPONSE; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN TARGETING; REVIEW;

ANTIGEN PRESENTATION; CD4-POSITIVE T-LYMPHOCYTES; ENDOSOMES; GENOME-WIDE ASSOCIATION STUDY; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84875588183     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.10.022     Document Type: Review

References (22)

1. Babst M. MVB vesicle formation: ESCRT-dependent, ESCRT-independent and everything in between. Current Opinion in Cell Biology 2011, 23:452-457.
2. Capelluto D.G. Tollip: a multitasking protein in innate immunity and protein trafficking. Microbes and Infection 2012, 14:140-147.
3. Hoorn T., Paul P., Janssen L., Janssen H., Neefjes J. Dynamics within tetraspanin pairs affect MHC class II expression. Journal of Cell Science 2012, 125:328-339.
4. Hor S., Ziv T., Admon A., Lehner P.J. Stable isotope labeling by amino acids in cell culture and differential plasma membrane proteome quantitation identify new substrates for the MARCH9 transmembrane E3 ligase. Molecular and Cellular Proteomics 2009, 8:1959-1971.
5. Lapaque N., Jahnke M., Trowsdale J., Kelly A.P. The HLA-DRalpha chain is modified by polyubiquitination. Journal of Biological Chemistry 2009, 284:7007-7016.
6. Ma J.K., Platt M.Y., Eastham-Anderson J., Shin J.S., Mellman I. MHC class II distribution in dendritic cells and B cells is determined by ubiquitin chain length. Proceedings of the National Academy of Sciences of the United States of America 2012, 109:8820-8827.
7. McGehee A.M., Strijbis K., Guillen E., Eng T., Kirak O., Ploegh H.L. Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production. PLoS One 2011, 6:e18817.
8. Miaczynska M., Pelkmans L., Zerial M. Not just a sink: endosomes in control of signal transduction. Current Opinion in Cell Biology 2004, 16:400-406.
9. Neefjes J., Jongsma M.L., Paul P., Bakke O. Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nature Reviews Immunology 2011, 11:823-836.
10. Ohmura-Hoshino M., Matsuki Y., Aoki M., Goto E., Mito M., Uematsu M., Kakiuchi T., Hotta H., Ishido S. Inhibition of MHC class II expression and immune responses by c-MIR. Journal of Immunology 2006, 177:341-354.
11. Paul P., van den Hoorn T., Jongsma M.L., Bakker M.J., Hengeveld R., Janssen L., Cresswell P., Egan D.A., van Ham M., Ten Brinke A., Ovaa H., Beijersbergen R.L., Kuijl C., Neefjes J. A genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell 2011, 145:268-283.
12. Pierre P., Turley S.J., Gatti E., Hull M., Meltzer J., Mirza A., Inaba K., Steinman R.M., Mellman I. Developmental regulation of MHC class II transport in mouse dendritic cells. Nature 1997, 388:787-792.
13. Sanderson F., Kleijmeer M.J., Kelly A., Verwoerd D., Tulp A., Neefjes J.J., Geuze H.J., Trowsdale J. Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science 1994, 266:1566-1569.
14. Shin J.S., Ebersold M., Pypaert M., Delamarre L., Hartley A., Mellman I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature 2006, 444:115-118.
15. Thibodeau J., Bourgeois-Daigneault M.C., Huppe G., Tremblay J., Aumont A., Houde M., Bartee E., Brunet A., Gauvreau M.E., de Gassart A., Gatti E., Baril M., Cloutier M., Bontron S., Fruh K., Lamarre D., Steimle V. Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. European Journal of Immunology 2008, 38:1225-1230.
16. van Niel G., Wubbolts R., Ten Broeke T., Buschow S.I., Ossendorp F.A., Melief C.J., Raposo G., van Balkom B.W., Stoorvogel W. Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination. Immunity 2006, 25:885-894.
17. Walseng E., Bakke O., Roche P.A. Major histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathway. Journal of Biological Chemistry 2008, 283:14717-14727.
18. Walseng E., Furuta K., Bosch B., Weih K.A., Matsuki Y., Bakke O., Ishido S., Roche P.A. Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells. Proceedings of the National Academy of Sciences of the United States of America 2010, 107:20465-20470.
19. Watts C., West M.A., Zaru R. TLR signalling regulated antigen presentation in dendritic cells. Current Opinion in Immunology 2010, 22:124-130.
20. Wilson N.S., Villadangos J.A. Regulation of antigen presentation and cross-presentation in the dendritic cell network: facts, hypothesis, and immunological implications. Advances in Immunology 2005, 86:241-305.
21. Wright M.H., Berlin I., Nash P.D. Regulation of endocytic sorting by ESCRT-DUB-mediated deubiquitination. Cell Biochemistry and Biophysics 2011, 60:39-46.
22. Zwart W., Griekspoor A., Kuijl C., Marsman M., van Rheenen J., Janssen H., Calafat J., van Ham M., Janssen L., van Lith M., Jalink K., Neefjes J. Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape. Immunity 2005, 22:221-233.