Nanosuspension for parenteral delivery of a p-terphenyl derivative: Preparation, characteristics and pharmacokinetic studies

Colloids and Surfaces B: Biointerfaces

Volumn 108, Issue , 2013, Pages 29-33

  Tian, Xiaona ^a   Li, Han ^a   Zhang, Dianrui ^a   Liu, Guangpu ^a   Jia, Lejiao ^a   Zheng, Dandan ^a   Shen, Jingyi ^a   Shen, Yuemao ^a   Zhang, Qiang ^b  

^a SHANDONG UNIVERSITY   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Dissolution; Mircrofluidization; Nanosuspension; P Terphenyl derivative; Pharmacokinetics; Precipitation

Indexed keywords

DRUG DELIVERY SYSTEM; MIRCROFLUIDIZATION; NANO-SUSPENSIONS; P-TERPHENYL; PHARMACOKINETIC STUDIES; POORLY SOLUBLE DRUGS; PRECIPITATION METHODS; SATURATION SOLUBILITY;

CRYSTALLINE MATERIALS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY; PHARMACOKINETICS; PRECIPITATION (CHEMICAL); SOLUBILITY; X RAY POWDER DIFFRACTION; ZETA POTENTIAL;

DISSOLUTION;

TERPHENYL DERIVATIVE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; DRY POWDER; FLUIDIZATION; FREEZE DRYING; MEAN RESIDENCE TIME; MICROFLUIDIZATION; NANOSUSPENSION; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRECIPITATION; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SUSPENSION; X RAY POWDER DIFFRACTION; ZETA POTENTIAL;

ANIMALS; ANTINEOPLASTIC AGENTS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DRUG CARRIERS; DRUG STABILITY; FREEZE DRYING; INFUSIONS, PARENTERAL; NANOPARTICLES; PARTICLE SIZE; RATS; RATS, WISTAR; SUSPENSIONS; TERPHENYL COMPOUNDS;

RATTUS;

EID: 84875581938     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2013.02.038     Document Type: Article

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