Diagnostic cancer genome sequencing and the contribution of germline variants

Science

Volumn 340, Issue 6127, 2013, Pages 1559-1562

  Kilpivaara, O ^a   Aaltonen, L A ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; DNA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE EPSILON; PROTEIN P53; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE GAMMA; POLD1 PROTEIN, HUMAN; POLE PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; TUMOR SUPPRESSOR PROTEIN;

CANCER; COST-BENEFIT ANALYSIS; GENOME; RESEARCH WORK;

CANCER DIAGNOSIS; CANCER SUSCEPTIBILITY; COLON CANCER; GENE MUTATION; GENE SEQUENCE; HUMAN; PENETRANCE; PREDICTION; PRIORITY JOURNAL; REVIEW; WHOLE GENOME SEQUENCING; GENETIC PREDISPOSITION; GENETICS; HUMAN GENOME; METHODOLOGY; MUTATION; NEOPLASM; NUCLEOTIDE SEQUENCE;

CELL CYCLE PROTEINS; DNA MUTATIONAL ANALYSIS; DNA POLYMERASE II; DNA POLYMERASE III; DNA-BINDING PROTEINS; GENETIC PREDISPOSITION TO DISEASE; GENOME, HUMAN; GERM-LINE MUTATION; HUMANS; NEOPLASMS; PENETRANCE; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

MLCS; MLOWN;

EID: 84875552595     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1233899     Document Type: Review

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