HIV Tat Induces Expression of ICAM-1 in HUVECs: Implications for miR-221/-222 in HIV-Associated Cardiomyopathy

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Duan, Ming ^a,b   Yao, Honghong ^a   Hu, Guoku ^c   Chen, XianMing ^c   Lund, Amie K ^d   Buch, Shilpa ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b JILIN UNIVERSITY   (China)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MICRORNA 221; MICRORNA 222; MITOGEN ACTIVATED PROTEIN KINASE; NEUTRALIZING ANTIBODY; OLIGONUCLEOTIDE; TRANSACTIVATOR PROTEIN;

ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENDOTHELIUM CELL; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS ASSOCIATED CARDIOMYOPATHY; IN VITRO STUDY; IN VIVO STUDY; MONOCYTE; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CARDIOMYOPATHIES; CELL ADHESION; CELLS, CULTURED; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MICRORNAS; RATS; RATS, INBRED F344; RATS, TRANSGENIC; REAL-TIME POLYMERASE CHAIN REACTION; TAT GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

ANIMALIA; HUMAN IMMUNODEFICIENCY VIRUS 1; RATTUS;

EID: 84875536063     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060170     Document Type: Article

References (49)

1. Barbaro G, Lipshultz SE, (2001) Pathogenesis of HIV-associated cardiomyopathy. Ann N Y Acad Sci 946: 57-81.
2. Barbaro G, Di Lorenzo G, Grisorio B, Barbarini G, (1998) Incidence of dilated cardiomyopathy and detection of HIV in myocardial cells of HIV-positive patients. Gruppo Italiano per lo Studio Cardiologico dei Pazienti Affetti da AIDS. N Engl J Med 339: 1093-1099.
3. Starc TJ, Lipshultz SE, Kaplan S, Easley KA, Bricker JT, et al. (1999) Cardiac complications in children with human immunodeficiency virus infection. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection (P2C2 HIV) Study Group, National Heart, Lung, and Blood Institute. Pediatrics 104: e14.
4. Dhawan S, Puri RK, Kumar A, Duplan H, Masson JM, et al. (1997) Human immunodeficiency virus-1-tat protein induces the cell surface expression of endothelial leukocyte adhesion molecule-1, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 in human endothelial cells. Blood 90: 1535-1544.
5. Lafrenie RM, Wahl LM, Epstein JS, Hewlett IK, Yamada KM, et al. (1996) HIV-1-Tat protein promotes chemotaxis and invasive behavior by monocytes. J Immunol 157: 974-977.
6. Carlos TM, Harlan JM, (1994) Leukocyte-endothelial adhesion molecules. Blood 84: 2068-2101.
7. Meerschaert J, Furie MB, (1995) The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J Immunol 154: 4099-4112.
8. Zietz C, Hotz B, Sturzl M, Rauch E, Penning R, et al. (1996) Aortic endothelium in HIV-1 infection: chronic injury, activation, and increased leukocyte adherence. Am J Pathol 149: 1887-1898.
9. Dhawan S, Weeks BS, Soderland C, Schnaper HW, Toro LA, et al. (1995) HIV-1 infection alters monocyte interactions with human microvascular endothelial cells. J Immunol 154: 422-432.
10. Ambros V, (2004) The functions of animal microRNAs. Nature 431: 350-355.
11. Bartel DP, (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
12. Kloosterman WP, Plasterk RH, (2006) The diverse functions of microRNAs in animal development and disease. Dev Cell 11: 441-450.
13. Hu G, Gong AY, Liu J, Zhou R, Deng C, et al. (2010) miR-221 suppresses ICAM-1 translation and regulates interferon-gamma-induced ICAM-1 expression in human cholangiocytes. Am J Physiol Gastrointest Liver Physiol 298: G542-550.
14. Yao H, Yang Y, Kim KJ, Bethel-Brown C, Gong N, et al. (2010) Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood 115: 4951-4962.
15. Reid W, Sadowska M, Denaro F, Rao S, Foulke J Jr, et al. (2001) An HIV-1 transgenic rat that develops HIV-related pathology and immunologic dysfunction. Proc Natl Acad Sci U S A 98: 9271-9276.
16. Lin Z, Natesan V, Shi H, Hamik A, Kawanami D, et al. (2010) A novel role of CCN3 in regulating endothelial inflammation. J Cell Commun Signal 4: 141-153.
17. Lund AK, Lucero J, Lucas S, Madden MC, McDonald JD, et al. (2009) Vehicular emissions induce vascular MMP-9 expression and activity associated with endothelin-1-mediated pathways. Arterioscler Thromb Vasc Biol 29: 511-517.
18. Hu G, Zhou R, Liu J, Gong AY, Eischeid AN, et al. (2009) MicroRNA-98 and let-7 confer cholangiocyte expression of cytokine-inducible Src homology 2-containing protein in response to microbial challenge. J Immunol 183: 1617-1624.
19. Chen XM, Splinter PL, O'Hara SP, LaRusso NF, (2007) A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem 282: 28929-28938.
20. Yao H, Peng F, Dhillon N, Callen S, Bokhari S, et al. (2009) Involvement of TRPC channels in CCL2-mediated neuroprotection against tat toxicity. J Neurosci 29: 1657-1669.
21. Gendelman HE, Orenstein JM, Martin MA, Ferrua C, Mitra R, et al. (1988) Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes. J Exp Med 167: 1428-1441.
22. Yao H, Kim K, Duan M, Hayashi T, Guo M, et al. (2011) Cocaine hijacks sigma1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS. J Neurosci 31: 5942-5955.
23. Buckner CM, Calderon TM, Willams DW, Belbin TJ, Berman JW, (2011) Characterization of monocyte maturation/differentiation that facilitates their transmigration across the blood-brain barrier and infection by HIV: implications for NeuroAIDS. Cell Immunol 267: 109-123.
24. Westendorp MO, Frank R, Ochsenbauer C, Stricker K, Dhein J, et al. (1995) Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375: 497-500.
25. Andras IE, Pu H, Deli MA, Nath A, Hennig B, et al. (2003) HIV-1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells. J Neurosci Res 74: 255-265.
26. Hayashi K, Pu H, Andras IE, Eum SY, Yamauchi A, et al. (2006) HIV-TAT protein upregulates expression of multidrug resistance protein 1 in the blood-brain barrier. J Cereb Blood Flow Metab 26: 1052-1065.
27. Prendergast MA, Rogers DT, Mulholland PJ, Littleton JM, Wilkins LH Jr, et al. (2002) Neurotoxic effects of the human immunodeficiency virus type-1 transcription factor Tat require function of a polyamine sensitive-site on the N-methyl-D-aspartate receptor. Brain Res 954: 300-307.
28. Ho AW, Wong CK, Lam CW, (2008) Tumor necrosis factor-alpha up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways. Immunobiology 213: 533-544.
29. Huang WC, Chen JJ, Chen CC, (2003) c-Src-dependent tyrosine phosphorylation of IKKbeta is involved in tumor necrosis factor-alpha-induced intercellular adhesion molecule-1 expression. J Biol Chem 278: 9944-9952.
30. Lin FS, Lin CC, Chien CS, Luo SF, Yang CM, (2005) Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells. J Cell Physiol 202: 464-473.
31. Ueda R, Kohanbash G, Sasaki K, Fujita M, Zhu X, et al. (2009) Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1. Proc Natl Acad Sci U S A 106: 10746-10751.
32. Vittecoq D, Escaut L, Merad M, Teicher E, Monsuez JJ, et al. (2003) Coronary heart disease in HIV-infected individuals. Adv Cardiol 40: 151-162.
33. Yunis NA, Stone VE, (1998) Cardiac manifestations of HIV/AIDS: a review of disease spectrum and clinical management. J Acquir Immune Defic Syndr Hum Retrovirol 18: 145-154.
34. Conaldi PG, Serra C, Dolei A, Basolo F, Falcone V, et al. (1995) Productive HIV-1 infection of human vascular endothelial cells requires cell proliferation and is stimulated by combined treatment with interleukin-1 beta plus tumor necrosis factor-alpha. J Med Virol 47: 355-363.
35. Grinspoon S, Carr A, (2005) Cardiovascular risk and body-fat abnormalities in HIV-infected adults. N Engl J Med 352: 48-62.
36. Ren Z, Yao Q, Chen C, (2002) HIV-1 envelope glycoprotein 120 increases intercellular adhesion molecule-1 expression by human endothelial cells. Lab Invest 82: 245-255.
37. Fiala M, Popik W, Qiao JH, Lossinsky AS, Alce T, et al. (2004) HIV-1 induces cardiomyopathyby cardiomyocyte invasion and gp120, Tat, and cytokine apoptotic signaling. Cardiovasc Toxicol 4: 97-107.
38. Kline ER, Sutliff RL, (2008) The roles of HIV-1 proteins and antiretroviral drug therapy in HIV-1-associated endothelial dysfunction. J Investig Med 56: 752-769.
39. Krieglstein CF, Granger DN, (2001) Adhesion molecules and their role in vascular disease. Am J Hypertens 14: 44S-54S.
40. Hope SA, Meredith IT, (2003) Cellular adhesion molecules and cardiovascular disease. Part I. Their expression and role in atherogenesis. Intern Med J 33: 380-386.
41. Jang Y, Lincoff AM, Plow EF, Topol EJ, (1994) Cell adhesion molecules in coronary artery disease. J Am Coll Cardiol 24: 1591-1601.
42. Xia M, Ling W, Zhu H, Ma J, Wang Q, et al. (2009) Anthocyanin attenuates CD40-mediated endothelial cell activation and apoptosis by inhibiting CD40-induced MAPK activation. Atherosclerosis 202: 41-47.
43. Luo SF, Fang RY, Hsieh HL, Chi PL, Lin CC, et al. (2010) Involvement of MAPKs and NF-kappaB in tumor necrosis factor alpha-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts. Arthritis Rheum 62: 105-116.
44. Lund AK, Lucero J, Herbert L, Liu Y, Naik JS, (2011) Human immunodeficiency virus transgenic rats exhibit pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 301: L315-326.
45. Friis-Moller N, Sabin CA, Weber R, d'Arminio Monforte A, El-Sadr WM, et al. (2003) Combination antiretroviral therapy and the risk of myocardial infarction. N Engl J Med 349: 1993-2003.
46. Friis-Moller N, Reiss P, Sabin CA, Weber R, Monforte A, et al. (2007) Class of antiretroviral drugs and the risk of myocardial infarction. N Engl J Med 356: 1723-1735.
47. Currier JS, Kendall MA, Henry WK, Alston-Smith B, Torriani FJ, et al. (2007) Progression of carotid artery intima-media thickening in HIV-infected and uninfected adults. AIDS 21: 1137-1145.
48. Holmberg SD, Moorman AC, Williamson JM, Tong TC, Ward DJ, et al. (2002) Protease inhibitors and cardiovascular outcomes in patients with HIV-1. Lancet 360: 1747-1748.
49. Mondal D, Pradhan L, Ali M, Agrawal KC, (2004) HAART drugs induce oxidative stress in human endothelial cells and increase endothelial recruitment of mononuclear cells: exacerbation by inflammatory cytokines and amelioration by antioxidants. Cardiovasc Toxicol 4: 287-302.